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    Disease diagnosis support system
    33.
    发明授权
    Disease diagnosis support system 有权
    疾病诊断支持系统

    公开(公告)号：US08386192B2

    公开(公告)日：2013-02-26

    申请号：US11916892

    申请日：2006-06-08

    申请人： Shingo Kawasaki ,  Noriyoshi Ichikawa ,  Fumio Kawaguchi ,  Hideo Kawaguchi ,  Naoki Tanaka ,  Masahiko Mikuni ,  Masato Fukuda

    发明人： Shingo Kawasaki ,  Noriyoshi Ichikawa ,  Fumio Kawaguchi ,  Hideo Kawaguchi ,  Naoki Tanaka ,  Masahiko Mikuni ,  Masato Fukuda

    IPC分类号： G01N33/48

    CPC分类号： A61B5/145 ,  A61B5/14546 ,  A61B5/14553 ,  G06F19/00 ,  G16H50/70

    摘要： There is provided a system for supporting the assessment as to which disease group the subject to be examined falls in or what position in the whole disease group the subject is in. This support system comprises the data storage part which stores feature values of optical bio-measurement data of many subjects including patients in multiple disease groups, the analysis part which extracts plural kinds of feature values from the optical bio-measurement data and the display part which displays the results of analysis in the analysis part associated with the dictionary data, wherein the display part produces a scatter diagram on which features values of the dictionary data are plotted, with one of the two feature values being plotted along the axis of abscissa and the other along the axis of ordinate, and displays the positions of the subject to be assessed on the scatter diagram superimposed on the scatter diagram. With this scatter diagram, the relationship between the features of the subject and the feature of the disease group can be known in one glance.

    摘要翻译： 提供了一种系统，用于支持被检查对象的哪一个疾病组属于被检者所在的整个疾病组中的哪一个或多个位置。该支持系统包括存储光学生物学特征值的数据存储部分， 包括多个疾病组中的患者的许多受试者的测量数据，从光学生物测量数据中提取多种特征值的分析部分和显示与字典数据相关联的分析部分中的分析结果的显示部分，其中 显示部分产生一个散点图，绘制了字典数据的特征值，其中两个特征值中的一个沿着横坐标轴绘制，另一个是沿着纵坐标轴绘制，并将主体的位置显示为 在散点图上进行评估，叠加在散点图上。 利用该散点图，可以一目了然地了解该受试者的特征与疾病组特征之间的关系。

    Five-phase motor with improved stator structure
    34.
    发明授权
    Five-phase motor with improved stator structure 有权
    具有改进定子结构的五相电动机

    公开(公告)号：US08203246B2

    公开(公告)日：2012-06-19

    申请号：US12710114

    申请日：2010-02-22

    申请人： Masayuki Nashiki ,  Naoki Tanaka ,  Hiroyasu Kudo

    发明人： Masayuki Nashiki ,  Naoki Tanaka ,  Hiroyasu Kudo

    IPC分类号： H02K3/28

    CPC分类号： H02K3/28 ,  H02K21/12 ,  H02K21/14 ,  H02K29/03

    摘要： A five-phase motor includes a stator and a movable member movable relative to the stator in a preset direction. The stator includes a stator core provided with five slots within 360 electrical degrees thereof. The five slots are arranged in the preset direction at preset first pitches. The stator includes at least one set of five-phase stator windings. The five-phase stator windings are arranged in the five slots relative to each other such that each of the five-phase stator windings is wound at a preset second pitch. The second pitch substantially corresponds to two of the first pitches.

    摘要翻译： 五相电动机包括定子和可相对于定子在预定方向上移动的可动构件。 定子包括在其360度电度范围内设置有五个槽的定子芯。 五个插槽以预设的第一间距布置在预设方向。 定子包括至少一组五相定子绕组。 五相定子绕组相对于彼此布置在五个槽中，使得五相定子绕组中的每一个以预设的第二间距被卷绕。 第二间距基本上对应于两个第一间距。

    STACKED STRUCTURE AND METHOD OF MANUFACTURING THE SAME
    35.
    发明申请
    STACKED STRUCTURE AND METHOD OF MANUFACTURING THE SAME 审中-公开
    堆叠结构及其制造方法

    公开(公告)号：US20120085573A1

    公开(公告)日：2012-04-12

    申请号：US13377882

    申请日：2010-05-07

    申请人： Hitoshi Noguchi ,  Naoki Tanaka ,  Tatsuya Nakamura

    发明人： Hitoshi Noguchi ,  Naoki Tanaka ,  Tatsuya Nakamura

    IPC分类号： H05K1/16 ,  H05K3/10

    CPC分类号： H05K1/162 ,  H01G4/1209 ,  H01G4/30 ,  H01G4/33 ,  H05K2201/0195 ,  H05K2203/1355

    摘要： A problem to be solved is to suppress deterioration of insulating properties in a stacked structure with a dielectric film formed by powder spraying coating process, and in a method of manufacturing the stacked structure. In a stacked structure according to the present invention, a dielectric layer 3 is provided between a first conductive layer 1 and a second conductive layer 2. The dielectric layer 3 includes an underlying layer 31 formed by applying a dispersion solution containing dielectric particles onto the first conductive layer 1, and a dielectric film 32 formed on the underlying layer 31 by powder spraying coating process. A method of manufacturing the stacked structure according to the present invention includes a dielectric layer forming step of forming the dielectric layer 3 on the first conductive layer 1, and a conductive layer forming step of forming the second conductive layer 2 on the dielectric layer 3. The dielectric layer forming step includes an underlying layer forming step of forming the underlying layer 31 by applying a dispersion solution containing dielectric particles onto the first conductive layer 1, and a dielectric film forming step of forming the dielectric film 32 on the underlying layer 31 by powder spraying coating process.

    摘要翻译： 要解决的问题是通过用粉末喷涂法形成的电介质膜来抑制层叠结构中的绝缘性的劣化，以及制造层叠结构的方法。 在根据本发明的堆叠结构中，电介质层3设置在第一导电层1和第二导电层2之间。电介质层3包括通过将包含电介质颗粒的分散溶液施加到第一导电层1上而形成的下层31 导电层1和通过粉末喷涂法在下层31上形成的电介质膜32。 根据本发明的制造叠层结构的方法包括在第一导电层1上形成电介质层3的介电层形成步骤和在电介质层3上形成第二导电层2的导电层形成步骤。 电介质层形成步骤包括通过将含有电介质颗粒的分散溶液施加到第一导电层1上形成下层31的下层形成步骤，以及电介质膜形成步骤，通过在第一导电层1上形成介电膜32在下层31上 粉末喷涂工艺。

    Optical measurement apparatus for living body
    36.
    发明授权
    Optical measurement apparatus for living body 有权
    生物体光学测量装置

    公开(公告)号：US08019399B2

    公开(公告)日：2011-09-13

    申请号：US10578725

    申请日：2004-11-01

    申请人： Shingo Kawasaki ,  Noriyoshi Ichikawa ,  Naoki Tanaka

    发明人： Shingo Kawasaki ,  Noriyoshi Ichikawa ,  Naoki Tanaka

    IPC分类号： A61B5/1455

    CPC分类号： G06K9/0051 ,  A61B5/0261 ,  A61B5/4064 ,  A61B5/7203 ,  G06T5/002

    摘要： A principal component analysis or an independent component analysis is conducted on the living body signals, e.g., local cerebral blood amount change signals obtained by the living body optical measurement to extract and display multiple component signals thereof. Signals other than the component signals containing noise are selected from these component signals automatically or manually, and the local cerebral blood amount change signals are reconstructed by using selected signals. The reconstructed signals is displayed and further subjected to the component analysis or the reconstruction as appropriate, and used for the profiling of information necessary for the diagnosis. Consequently, high-precision target signals can be obtained by completely removing external noise included in the living body signals, particularly the noise which cannot be adequately removed by the moving average and the filtering processings.

    摘要翻译： 对生物体信号进行主成分分析或独立成分分析，例如通过生物体光学测定得到的局部脑血量变化信号，提取并显示多个成分信号。 从包含噪声的分量信号以外的信号自动地或手动地从这些分量信号中选择，并且通过使用所选择的信号重建局部脑血量变化信号。 显示重建的信号，并进一步进行成分分析或重建，并用于诊断所需信息的分析。 因此，通过完全去除包括在生物体信号中的外部噪声，特别是通过移动平均和过滤处理不能充分消除的噪声，可以获得高精度目标信号。

    CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP
    38.
    发明申请
    CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP 审中-公开
    具有取代的烷基的环胺衍生物

    公开(公告)号：US20090306059A1

    公开(公告)日：2009-12-10

    申请号：US11915522

    申请日：2006-05-26

    申请人： Tomio Kimura ,  Naoki Tanaka ,  Hiroyuki Kobayashi ,  Atsuhiro Sugidachi

    发明人： Tomio Kimura ,  Naoki Tanaka ,  Hiroyuki Kobayashi ,  Atsuhiro Sugidachi

    IPC分类号： A61K31/541 ,  C07D413/06 ,  A61K31/5377 ,  C07D417/06 ,  C07D401/06 ,  A61K31/4545 ,  A61P7/02

    CPC分类号： F16D3/2233 ,  F16D2003/22309 ,  Y10T403/32655

    摘要： A compound having the general formula (I), pharmacologically acceptable salts thereof or prodrugs thereof: [wherein R1 represents a hydrogen atom, a C1-C6 alkyl group which may be substituted, a C3-C6 cycloalkyl group which may be substituted, a C1-C6 alkoxy group which may be substituted or a C6-C10 aryl group which may be substituted; R2 represents a hydrogen atom, a halogen atom, a carboxy group, a C2-C7 alkoxycarbonyl group, a carbamoyl group, a cyano group, a C1-C6 alkyl group, a halogeno C1-C6 alkyl group, a C1-C6 alkyl group substituted by a heteroaryl group, a C1-C6 alkoxy group, a halogeno C1-C6 alkoxy group, a hydroxy C1-C6 alkyl group, a C2-C12 alkoxyalkyl group, a formyl group, a C2-C7 alkanoyl group, a C4-C7 cycloalkylcarbonyl group, a C2-C7 alkylcarbamoyl group, a di(C1-C6 alkyl)carbamoyl group, a group of formula R4—CO—CR5R6—(CH2)m—, a group of formula R7—CO—(CH2)l—N(R8)— or a sulfamoyl C1-C6 alkyl group; R3 represents a substituted C1-C6 alkyl group, a heterocyclyl group or a heterocyclyl group substituted with 1 to 5 substituents; X1, X2, X3, X4 and X5 each independently represents a hydrogen atom, a halogen atom, an amino group, a carboxy group, a carbamoyl group, a cyano group, a nitro group, a C1-C6 alkyl group, a halogeno C1-C6 alkyl group, a C1-C6 alkoxy group, or a halogeno C1-C6 alkoxy group; and n represents an integer of 0 to 2].

    摘要翻译： 具有通式（I）的化合物，其药学上可接受的盐或其前药：其中R1表示氢原子，可被取代的C1-C6烷基，可被取代的C3-C6环烷基，C1 可被取代的-C6烷氧基或可被取代的C6-C10芳基; R2表示氢原子，卤素原子，羧基，C2-C7烷氧基羰基，氨基甲酰基，氰基，C1-C6烷基，卤代C1-C6烷基，C1-C6烷基 被杂芳基，C 1 -C 6烷氧基，卤代C 1 -C 6烷氧基，羟基C 1 -C 6烷基，C 2 -C 12烷氧基烷基，甲酰基，C 2 -C 7烷酰基， C7环烷基羰基，C2-C7烷基氨基甲酰基，二（C1-C6烷基）氨基甲酰基，式R4-CO-CR5R6-（CH2）m-的基团，式R7-CO-（CH2） （R8） - 或氨磺酰基C1-C6烷基; R 3表示取代的C 1 -C 6烷基，杂环基或被1至5个取代基取代的杂环基; X1，X2，X3，X4和X5各自独立地表示氢原子，卤素原子，氨基，羧基，氨基甲酰基，氰基，硝基，C1-C6烷基，卤代C1 C 1-6烷基，C 1 -C 6烷氧基或卤代C 1 -C 6烷氧基; n表示0〜2的整数]。

    BIOLOGICAL PHOTOMETRIC DEVICE
    39.
    发明申请
    BIOLOGICAL PHOTOMETRIC DEVICE 有权
    生物光学设备

    公开(公告)号：US20090054885A1

    公开(公告)日：2009-02-26

    申请号：US11816452

    申请日：2006-02-02

    申请人： Shingo Kawasaki ,  Naoki Tanaka

    发明人： Shingo Kawasaki ,  Naoki Tanaka

    IPC分类号： A61B18/18

    CPC分类号： A61B5/0059 ,  A61B5/14546 ,  A61B5/14553 ,  G01N21/4795

    摘要： A biological photometric device includes a light irradiating unit for irradiating an object to be examined with light having a predetermined wavelength and sympathizing with oxygenated hemoglobin and deoxygenated hemoglobin through an optical fiber, a light detecting unit for detecting and amplifying light passing through a detecting optical fiber and the object as detected signals, a signal processing unit adapted for computing hemoglobin time change information based on oxygenated hemoglobin, deoxygenated hemoglobin and total hemoglobin in the object from the detected signals light detecting unit, and including a noise detector for arithmetically processing the detected signals and determining/detecting whether the time change information is noise attributed to the presence of obstacles to passing of light between the object and the end face of the optical fiber or noise attributed to the damage to the light irradiating unit, and a display unit for displaying the noise signals.

    摘要翻译： 一种生物测光装置，其特征在于，包括：光照射单元，用于通过光纤对具有预定波长的光进行照射并与氧合血红蛋白和脱氧血红蛋白同步的光进行照射，光检测单元，用于检测和放大通过检测光纤的光 所述物体作为检测信号，信号处理单元适于根据来自检测信号光检测单元的所述物体中的氧合血红蛋白，脱氧血红蛋白和总血红蛋白计算血红蛋白时间变化信息，并且包括用于对检测信号进行算术处理的噪声检测器 以及确定/检测时间变化信息是否归因于在光纤的物体和端面之间的光通过的障碍物的存在或归因于对光照射单元的损坏的噪声的噪声;以及显示单元，用于显示 噪声信号。

    Living body photometric device
    40.
    发明申请
    Living body photometric device 有权
    生命体测光装置

    公开(公告)号：US20060206017A1

    公开(公告)日：2006-09-14

    申请号：US10526893

    申请日：2003-09-05

    申请人： Shingo Kawasaki ,  Naoki Tanaka

    发明人： Shingo Kawasaki ,  Naoki Tanaka

    IPC分类号： A61B5/00

    CPC分类号： A61B5/1455

    摘要： By making use of a set of loading of stimulation and no loading, variation signals in time of hemoglobin density at a plurality of measurement points of a subject attached of an optical measurement probe and corresponding to a plurality of channels are detected, and for the respective detected hemoglobin variation signals principal component analysis is performed as well as a representative signal having a higher contribution rate is extracted and the extracted representative signal is displayed on a monitor. A correlation between the representative signal and a task reference and response waveform representing a response pattern of a living body in response to a stimulation task is calculated, and a representative signal having the highest correlation value as calculated is displayed in a discriminable manner from the other signals as a task related signal which responds most to the stimulation given to the subject. From weights of the respective channels for the representative signal displayed as the task related signal, an optical measurement point or region, which responds most to the task is identified and displayed in discriminable manner.

    摘要翻译： 通过利用一组刺激负荷和无载荷，检测在光学测量探针附着并对应于多个通道的受试者的多个测量点处的血红蛋白密度的变化信号，并且对于相应的 检测出的血红蛋白变化信号进行主成分分析，并提取具有较高贡献率的代表信号，并将提取的代表信号显示在监视器上。 计算代表信号和表示响应于刺激任务的生物体的响应模式的任务参考和响应波形之间的相关性，并且以可计算的方式从其他方式显示具有计算的相关值最高的代表信号 信号作为对给予对象的刺激最响应的任务相关信号。 从显示为任务相关信号的代表信号的相应通道的权重中，以可区分的方式识别和显示对该任务最响应的光学测量点或区域。