Microfluidic Check Valves With Enhanced Cracking Pressures and Methods of Making the Same
    31.
    发明申请
    Microfluidic Check Valves With Enhanced Cracking Pressures and Methods of Making the Same 审中-公开
    具有增强裂纹压力的微流控止回阀及其制作方法

    公开(公告)号:US20120241017A1

    公开(公告)日:2012-09-27

    申请号:US13427282

    申请日:2012-03-22

    IPC分类号: F16K21/04 F16K51/00

    摘要: Microfluidic normally closed check valves and methods of making and using the same are provided. The check valves include an orifice, an occluding portion, and one or more attachment members which urge the occluding portion into a position occluding the orifice. In various embodiments, the attachment member or members are pre-stressed by thermal annealing to introduce tensile stress of at least 800 PSI therewithin, thereby increasing the cracking pressure of the valve

    摘要翻译: 提供微流体常闭止回阀及其制作及使用方法。 止回阀包括孔口,闭塞部分和一个或多个附着构件,其将阻塞部分推入封闭孔口的位置。 在各种实施例中,通过热退火对附接构件进行预应力,以在其中引入至少800PSI的拉伸应力,从而增加阀的开启压力

    Integrated capacitive microfluidic sensors method and apparatus
    34.
    发明授权
    Integrated capacitive microfluidic sensors method and apparatus 有权
    集成电容微流体传感器的方法和装置

    公开(公告)号:US07796371B2

    公开(公告)日:2010-09-14

    申请号:US11830581

    申请日:2007-07-30

    IPC分类号: H01G7/00

    摘要: A micro fluidic device and method for capacitive sensing. The device includes a fluid channel including an inlet at a first end and an outlet at a second end, a cavity region coupled to the fluid channel, and a polymer based membrane coupled between the fluid channel and the cavity region. Additionally, the device includes a first capacitor electrode coupled to the membrane, a second capacitor electrode coupled to the cavity region and physically separated from the first capacitor electrode by at least the cavity region, and an electrical power source coupled between the first capacitor electrode and the second capacitor electrode and causing an electric field at least within the cavity region. The polymer based membrane includes a polymer.

    摘要翻译: 一种用于电容式感测的微流体装置和方法。 该装置包括流体通道,其包括在第一端处的入口和在第二端处的出口,耦合到流体通道的空腔区域以及耦合在流体通道和腔区域之间的基于聚合物的膜。 另外,该器件包括耦合到膜的第一电容器电极,耦合到空腔区域的第二电容器电极,并且至少通过腔区域与第一电容器电极物理分离;以及电源,耦合在第一电容器电极和 所述第二电容器电极至少在所述腔区域内引起电场。 基于聚合物的膜包括聚合物。

    MICROFLUIDIC VALVE HAVING FREE-FLOATING MEMBER AND METHOD OF FABRICATION
    36.
    发明申请
    MICROFLUIDIC VALVE HAVING FREE-FLOATING MEMBER AND METHOD OF FABRICATION 有权
    具有自由浮动构件的微流控阀和制造方法

    公开(公告)号:US20100025613A1

    公开(公告)日:2010-02-04

    申请号:US12565636

    申请日:2009-09-23

    IPC分类号: F16K17/02 B21D53/10

    摘要: Micro check valves having a free-floating member for controlling flow of fluid in microfluidic and biomedical applications and methods of fabrication. A micro check valve includes a valve seat, a valve cap that contacts the valve seat and an untethered floating member that can move between the valve seat and the valve cap. Certain micro check valves have zero cracking pressure and no reverse leakage. Certain other valves may be configured to permit flow of fluid within a pressure range. The floating member can be solid or define an orifice, and the valve seat can have one or two levels. Valves can be configured to allow fluid to flow when the floating member is pushed by fluid against the valve cap or against the valve seat. The valve seat may be silicon or another material that is compatible with micromachining processes, and the valve cap and the floating member may be a polymer such as Parylene.

    摘要翻译: 微型止回阀具有用于控制微流体和生物医学应用中的流体流动的自由浮动部件和制造方法。 微型止回阀包括阀座,接触阀座的阀盖和可在阀座与阀盖之间移动的无阻力浮动件。 某些微型止回阀具有零开裂压力,无反向泄漏。 某些其它阀可以被配置为允许流体在压力范围内流动。 浮动构件可以是固定的或限定孔口,并且阀座可以具有一个或两个水平面。 阀可以被配置为当浮动构件被流体压靠在阀盖或阀座上时流体流动。 阀座可以是硅或与微加工过程相容的另一种材料,阀帽和浮动元件可以是聚合物,例如聚对二甲苯。

    Resonance-induced sensitivity enhancement method for conductivity sensors
    38.
    发明授权
    Resonance-induced sensitivity enhancement method for conductivity sensors 失效
    电导率传感器的共振诱导灵敏度增强方法

    公开(公告)号:US07629797B2

    公开(公告)日:2009-12-08

    申请号:US11697060

    申请日:2007-04-05

    IPC分类号: G01R27/26

    摘要: Methods and systems for improving the sensitivity of a variety of conductivity sensing devices, in particular capacitively-coupled contactless conductivity detectors. A parallel inductor is added to the conductivity sensor. The sensor with the parallel inductor is operated at a resonant frequency of the equivalent circuit model. At the resonant frequency, parasitic capacitances that are either in series or in parallel with the conductance (and possibly a series resistance) is substantially removed from the equivalent circuit, leaving a purely resistive impedance. An appreciably higher sensor sensitivity results. Experimental verification shows that sensitivity improvements of the order of 10,000-fold are possible. Examples of detecting particulates with high precision by application of the apparatus and methods of operation are described.

    摘要翻译: 用于提高各种电导率传感装置的灵敏度的方法和系统,特别是电容耦合的非接触电导检测器。 并联电感器被添加到电导率传感器。 具有并联电感器的传感器以等效电路模型的谐振频率工作。 在谐振频率下,与电导串联或并联的寄生电容(和可能的串联电阻)基本上从等效电路中去除,留下纯电阻阻抗。 传感器敏感度会更高。 实验验证表明灵敏度提高可达10,000倍。 描述了通过应用该装置和操作方法检测高精度的微粒的实例。

    Integrated surface-machined micro flow controller method and apparatus
    40.
    发明申请
    Integrated surface-machined micro flow controller method and apparatus 审中-公开
    综合表面加工微流量控制器的方法和装置

    公开(公告)号:US20080210306A1

    公开(公告)日:2008-09-04

    申请号:US11515794

    申请日:2006-09-06

    摘要: A surface-micromachined mass flow controller (MFC) comprises an electrostatically actuated microvalve integrated with a thermal flow sensor. The microvalve comprises a normally-open diaphragm defining an aperture allowing fluid communication between first and second flow channels. The diaphragm includes a second electrode actuable toward a valve seat including a first electrode. Fabricated utilizing a multilayer Parylene process, the active microvalve and the flow sensor are integrated onto a single chip to perform closed-loop flow control. For flow control, both Pulse Width Modulation (PWM) and actuation voltage adjustment are demonstrated.

    摘要翻译: 表面微加工质量流量控制器(MFC)包括与热流传感器集成的静电致动微型阀。 微型阀包括限定允许第一和第二流动通道之间流体连通的孔的常开的隔膜。 隔膜包括能够朝向包括第一电极的阀座致动的第二电极。 采用多层Parylene工艺制造,将活性微型阀和流量传感器集成到单个芯片上,以执行闭环流量控制。 对于流量控制,展示了脉宽调制(PWM)和启动电压调节。