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    READER DEVICE FOR LUMINESCENT IMMUNOASSAYS
    32.
    发明申请
    READER DEVICE FOR LUMINESCENT IMMUNOASSAYS 审中-公开
    用于发光免疫测定的读取装置

    公开(公告)号：US20140154792A1

    公开(公告)日：2014-06-05

    申请号：US14234136

    申请日：2012-07-20

    Applicant: BIOSENSIA PATENTS LIMITED

    Inventor： Shane Moynihan ,  Diarmuid Flavin

    IPC: G01N21/64 ,  G01N33/53

    CPC classification number: G01N21/6486 ,  G01N21/278 ,  G01N21/645 ,  G01N21/6452 ,  G01N33/5302 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6441 ,  G01N2021/6471 ,  G01N2201/0624 ,  G01N2201/0627 ,  G01N2201/0648 ,  G01N2201/0693

    Abstract: The present disclosure, among other things, describes a reader system for analyzing one or more analytes in a fluid sample, comprising a casing (204) with at least one port (201) leading to a holster (301) which is configured to receive a cartridge (107) comprising a vertically oriented immunoassay device for analyzing one or more analytes in a fluid sample, an optical system (121) with excitation optics comprising a light source (302) and an excitation lens (305) configured to transmit light from the light source (302) and thereby excite a region of the vertically oriented immunoassay device when a cartridge (107) is placed in the holster (301), and collection optics comprising a photosensor (306) and a collection lens (307) configured to collect emitted light from the vertically oriented immunoassay device when a cartridge (107) is placed in the holster (301), an electromechanical motor system (106) configured to move the holster (301) in a vertical direction with respect to the optical system (121) so that the optical system (121) can interrogate different regions of the vertically oriented immunoassay device when a cartridge (107) is placed in the holster (301), and one or more digital processors (104a, 104b) and associated electronics configured to receive data from and control the optical system (121) and to control the electromechanical motor system (106).

    Abstract translation: 本公开尤其描述了用于分析流体样品中的一种或多种分析物的读取器系统，其包括具有至少一个通向皮套（301）的端口（201）的壳体（204），所述壳体被配置为接收 盒（107）包括用于分析流体样品中的一种或多种分析物的垂直取向的免疫测定装置，具有激发光学元件的光学系统（121），其包括光源（302）和激发透镜（305），所述光学系统被配置为透射来自 并且由此当盒（107）被放置在机架（301）中时激发垂直取向的免疫测定装置的区域，并且收集光学器件包括光电传感器（306）和收集透镜（307），其被配置为收集 当盒（107）被放置在机架（301）中时，来自垂直取向的免疫测定装置的光发射;机构电动机系统（106），被配置成相对于所述光学装置在垂直方向上移动所述机架 cal系统（121），使得当盒（107）被放置在机架（301）中时，光学系统（121）可以询问垂直定向的免疫测定装置的不同区域，以及一个或多个数字处理器（104a，104b）和 配置为从光学系统（121）接收数据和控制光学系统（121）并控制机电马达系统（106）的相关电子设备。

    LED spotlight
    34.
    发明授权
    LED spotlight 有权
    LED射灯

    公开(公告)号：US07798667B2

    公开(公告)日：2010-09-21

    申请号：US12003008

    申请日：2007-12-19

    Applicant: Donald L. Klipstein

    Inventor： Donald L. Klipstein

    IPC: F21V33/00 ,  F21V7/00 ,  G02B1/00

    CPC classification number: F21V29/74 ,  B60Q1/0483 ,  B60Q1/245 ,  F21L4/005 ,  F21L4/027 ,  F21L4/06 ,  F21S45/47 ,  F21V7/0008 ,  F21V23/0414 ,  F21V27/00 ,  F21V27/02 ,  F21V29/89 ,  F21Y2113/13 ,  F21Y2115/10 ,  G01N21/643 ,  G01N21/8806 ,  G01N2201/0221 ,  G01N2201/0693 ,  H05B33/0803 ,  H05B33/0818

    Abstract: LED lamp has LEDs aimed rearwards with either a concave mirror to the rear of each LED, or one concave mirror to the rear of two or more LEDs, collecting the light from the LEDs to form a forward projecting beam. LEDs may be high power types that require heatsinking. LED lamp may have a lens forward of each LED to collimate the radiation produced by the LEDs into a beam, where at least one lens has at least one aspheric curved surface. LED lamp may have a transparent reflective optic to collimate the radiation produced by each LED into a beam. LEDs mounted to heatsink mount with spokes and ring to support LEDs in place above mirror and conduct away heat.

    Abstract translation: LED灯具有朝向后方的LED，其中每个LED的后部具有凹面镜，或者到两个或更多个LED的后面的一个凹面镜，收集来自LED的光以形成向前突出的光束。 LED可能是需要散热的高功率类型。 LED灯可以具有每个LED前方的透镜，以将由LED产生的辐射准直成束，其中至少一个透镜具有至少一个非球面曲面。 LED灯可以具有透明反射光学器件，以将由每个LED产生的辐射准直成束。 LED安装在散热片安装件上，带有辐条和环，以便将镜子上的LED保持在适当的位置，并散热。

    LED inspection lamp and LED spot light
    35.
    发明授权
    LED inspection lamp and LED spot light 有权
    LED检测灯和LED射灯

    公开(公告)号：US07568816B2

    公开(公告)日：2009-08-04

    申请号：US11695894

    申请日：2007-04-03

    Applicant: Jack Brass ,  Richard J. Doran ,  Donald L. Klipstein ,  Thomas M. Lemons ,  Bjarki Hallgrimson ,  Sarah Dobbin

    Inventor： Jack Brass ,  Richard J. Doran ,  Donald L. Klipstein ,  Thomas M. Lemons ,  Bjarki Hallgrimson ,  Sarah Dobbin

    IPC: F21L4/02

    CPC classification number: G01N21/6428 ,  G01N21/31 ,  G01N21/6402 ,  G01N21/6447 ,  G01N21/8803 ,  G01N2201/0221 ,  G01N2201/0612 ,  G01N2201/0621 ,  G01N2201/0627 ,  G01N2201/0638 ,  G01N2201/0693 ,  Y10S362/80

    Abstract: An LED inspection lamp has plurality of LED sources for emitting electromagnetic radiation at different peak wavelengths for causing visible fluorescence in different leak detection dyes. A lens is associated with each LED. Radiation passing through lenses is superimposed in target area at target distance. Another LED inspection lamp has plurality of LEDs emitting electromagnetic radiation at a peak wavelength. A lens adaptor has lens housing for attachment to LED inspection lamp with a single LED for causing visible fluorescence, and a lens. Substantially all of the radiation from the LED passes through the lens and is focused in a target area at a target distance from the lenses. LED spot lights have a similar configuration. The LEDs may produce white light from distinct LEDs or from white LEDs. The light may be a flashlight or fixed spot light.

    Abstract translation: LED检查灯具有多个LED源，用于发射不同峰值波长的电磁辐射，以在不同的泄漏检测染料中引起可见荧光。 镜头与每个LED相关联。 通过透镜的辐射以目标距离叠加在目标区域中。 另一个LED检查灯具有发射峰值波长的电磁辐射的多个LED。 镜头适配器具有透镜壳体，用于附接到具有用于引起可见荧光的单个LED的LED检查灯和透镜。 基本上来自LED的所有辐射通过透镜并聚焦在与透镜目标距离处的目标区域中。 LED射灯具有相似的配置。 LED可能产生来自不同LED或白色LED的白光。 灯可能是手电筒或固定点灯。

    Calibrator for fluorosensor
    36.
    发明授权
    Calibrator for fluorosensor 有权
    氟传感器校准器

    公开(公告)号：US07416701B2

    公开(公告)日：2008-08-26

    申请号：US11299784

    申请日：2005-12-13

    Applicant: Eugene Tokhtuev ,  Anatoly Skirda ,  Viktor Slobodyan ,  Christopher Owen

    Inventor： Eugene Tokhtuev ,  Anatoly Skirda ,  Viktor Slobodyan ,  Christopher Owen

    IPC: G01N21/64 ,  G01N21/66 ,  G01N15/06 ,  G01N33/00 ,  C12Q1/68

    CPC classification number: G01N21/645 ,  G01N21/15 ,  G01N21/276 ,  G01N21/278 ,  G01N21/6486 ,  G01N21/8507 ,  G01N33/1826 ,  G01N2021/6417 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6478 ,  G01N2201/0218 ,  G01N2201/024 ,  G01N2201/0627 ,  G01N2201/0693 ,  Y10T29/49 ,  Y10T29/49002 ,  Y10T436/108331

    Abstract: A multichannel fluorosensor includes an optical module and an electronic module combined in a watertight housing with an underwater connector. The fluorosensor has an integral calibrator for periodical sensitivity validation of the fluorosensor. The optical module has one or several excitation channels and one or several emission channels that use a mutual focusing system. To increase efficiency, the excitation and emission channels each have a micro-collimator made with one or more ball lenses. Each excitation channel has a light emitting diode and an optical filter. Each emission channel has a photodiode with a preamplifier and an optical filter. The electronic module connects directly to the optical module and includes a lock-in amplifier, a power supply and a controller with an A/D converter and a connector. The calibrator provides a response proportional to the excitation intensity, and matches with spectral parameter of fluorescence for the analyzed fluorescent substance.

    Abstract translation: 多通道氟传感器包括光学模块和组合在具有水下连接器的防水壳体中的电子模块。 氟传感器具有用于氟传感器周期灵敏度验证的积分校准器。 光学模块具有一个或多个激发通道和使用相互聚焦系统的一个或多个发射通道。 为了提高效率，激发和发射通道各自具有由一个或多个球透镜制成的微型准直器。 每个激励通道都有一个发光二极管和一个滤光器。 每个发射通道具有带有前置放大器和光学滤波器的光电二极管。 电子模块直接连接到光模块，包括锁定放大器，电源和带有A / D转换器和连接器的控制器。 校准器提供与激发强度成比例的响应，并与分析的荧光物质的荧光光谱参数相匹配。

    Automated process monitoring
    39.
    发明授权
    Automated process monitoring 失效
    自动过程监控

    公开(公告)号：US4938602A

    公开(公告)日：1990-07-03

    申请号：US329293

    申请日：1989-03-27

    Applicant: Joe T. May ,  Edward A. Casacia

    Inventor： Joe T. May ,  Edward A. Casacia

    IPC: G01J1/16 ,  G01N21/01 ,  G01N21/09 ,  G01N21/25 ,  G01N21/85 ,  G03F7/30

    CPC classification number: G01N21/251 ,  G01N21/8507 ,  G03F7/30 ,  G01J1/1626 ,  G01J2001/161 ,  G01J2001/1636 ,  G01N2021/0162 ,  G01N21/09 ,  G01N2201/0693 ,  G01N2201/12761

    Abstract: Instrumentation for measuring the amount of material dissolved in a liquid solution which utilizes electro-optic technology based on the Beer-Lambert Law is implemented either as a portable, battery powered model or integrated in an automated process monitoring system. In the portable, battery powered model, a sample probe (14) is inserted into a solution to be measured. The results of the measurement are displayed on a display (22). The displayed results are frozen for a predetermined period of time at the expiration of which, the power is turned off to conserve battery power. In the automated process monitoring model, a solution loading analyzer (100) is supplied with a sample of solution to be analyzed. A probe (14) positioned in a measurement well (200) is used to determine the ratio of incident light to light transmitted through the sample. A spray nozzle (212) is used for cleaning the probe head (16).

    Abstract translation: 用于测量溶解在基于Beer-Lambert法的电光技术的液体溶液中的材料的量的仪器可以作为便携式，电池供电型或者集成在自动化过程监控系统中来实现。 在便携式电池供电的模型中，将样品探针（14）插入待测量的溶液中。 测量结果显示在显示器（22）上。 显示的结果被冻结预定的时间段，在此期间电源被关闭以节省电池电力。 在自动化过程监控模型中，向溶液负载分析仪（100）提供待分析的溶液样品。 位于测量井（200）中的探头（14）用于确定入射光与穿过样品的光的比例。 喷嘴（212）用于清洁探头（16）。

    IMPLANTABLE APPARATUS FOR SENSING BIOLOGIC SIGNALS
    40.
    发明公开
    IMPLANTABLE APPARATUS FOR SENSING BIOLOGIC SIGNALS 审中-公开

    公开(公告)号：US20240130684A1

    公开(公告)日：2024-04-25

    申请号：US18399914

    申请日：2023-12-29

    Applicant: EFFERENT LABS, INC.

    Inventor： Marek Kowarz ,  Spencer Rosero

    IPC: A61B5/00 ,  A61B10/02 ,  G01N21/64

    CPC classification number: A61B5/6865 ,  A61B10/02 ,  G01N21/64 ,  A61B2560/0219 ,  A61B2562/0233 ,  G01N2201/062 ,  G01N2201/0693

    Abstract: An implantable apparatus for physiological measurement in a host organism has an implantable sample chamber having a measurement port and live cells that are treated to fluoresce in response to light having an excitation wavelength. An optical sensor housing implanted within the host organism has a window to convey excitation light output and receive fluorescent light; a coupling that couples the measurement port of the sample chamber to the window; an optical chamber partitioned into an excitation sub-chamber and a detection sub-chamber, wherein both sub-chambers are in optical communication with the window; an excitation source energizable to direct excitation light through the excitation sub-chamber and to the window; and a detector in the path of fluorescent light received from the live cells. A signal processing apparatus is energizable to acquire and process a detector signal and to transmit a processed signal that is indicative of fluorescent light energy.

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