-
公开(公告)号:US11713450B2
公开(公告)日:2023-08-01
申请号:US17328687
申请日:2021-05-24
发明人: Martin Lock , Mauricio Alvira
IPC分类号: C12N7/02 , B01J20/281 , B01D15/08 , C12N7/00 , B01J41/13 , C12N15/86 , B01J47/022 , B01D15/38 , C12N15/864 , G01N21/33 , B01J41/05 , B01D15/16 , B01D15/36 , B01J41/20
CPC分类号: C12N7/02 , B01D15/08 , B01D15/3804 , B01J20/281 , B01J41/13 , B01J47/022 , C12N7/00 , C12N15/86 , C12N15/8645 , G01N21/33 , B01D15/166 , B01D15/363 , B01J41/05 , B01J41/20 , C12N2750/14143 , C12N2750/14151 , B01D15/3804 , B01D15/363
摘要: A two-step chromatography purification scheme is described which selectively captures and isolates the genome-containing rAAV vector particles from the clarified, concentrated supernatant of a rAAV production cell culture. The process utilizes an affinity capture method performed at a high salt concentration followed by an anion exchange resin method performed at high pH to provide rAAV vector particles which are substantially free of rAAV intermediates.
-
公开(公告)号:US11658322B2
公开(公告)日:2023-05-23
申请号:US17088519
申请日:2020-11-03
发明人: Timothy Manning Swager , Jeffrey C. Grossman , Sibo Lin , Yoonseob Kim , Yanming Wang , Arthur France-Lanord , You-Chi Wu , Yifan Li , Yichong Wang
IPC分类号: H01M8/10 , B01J47/12 , B01J41/07 , C08J5/22 , B01J41/13 , H01M8/1032 , H01M8/1027
CPC分类号: H01M8/1032 , B01J41/07 , B01J41/13 , B01J47/12 , C08J5/2287 , H01M8/1027 , H01M2008/1095
摘要: A major challenge in the development of anion exchange membranes for fuel cells is the design and synthesis of highly stable (chemically and mechanically) and conducting membranes. Membranes that can endure highly alkaline environments while rapidly transporting hydroxides are desired. A design for using cross-linked polymer membranes is disclosed to produce ionic highways along charge delocalized pyrazolium and homoconjugated triptycenes. The ionic highway membranes show improved performance in key parameters. Specifically, a conductivity of 111.6 mS cm−1 at 80° C. was obtained with a low 7.9% water uptake and 0.91 mmol g−1 ion exchange capacity. In contrast to existing materials, these systems have higher conductivities at reduced hydration and ionic exchange capacities, emphasizing the role of the highway. The membranes retain more than 75% of initial conductivity after 30 days of alkaline stability test. This effective water management through ionic highways is confirmed by density functional theory and Monte Carlo studies. A single cell with platinum group metal catalysts at 80° C. showed a high peak density of 0.73 W cm−2 (0.45 W cm−2 from silver-based cathode) and stable performance during 400 h tests.
-
公开(公告)号:US11542181B2
公开(公告)日:2023-01-03
申请号:US15779990
申请日:2016-11-30
IPC分类号: C02F1/42 , B01D15/36 , B01D63/06 , B01D65/02 , B01J39/04 , B01J39/19 , B01J39/26 , B01J41/04 , B01J41/12 , B01J41/13 , B01J47/127 , C02F1/44 , C02F101/10 , C02F101/20 , C02F101/30
摘要: In one aspect, separation media are described herein operable for removing one or more water contaminants including NOM and derivatives thereof. Briefly, a separation medium includes a nanoparticle support and an oligomeric stationary phase forming a film on individual nanoparticles of the support, the film having thickness of 1 to 100 nm. In some embodiments, oligomeric chains of the stationary phase are covalently bonded to the individual nanoparticles.
-
公开(公告)号:US11504707B2
公开(公告)日:2022-11-22
申请号:US15804868
申请日:2017-11-06
申请人: DIONEX CORPORATION
发明人: Christopher A. Pohl
IPC分类号: B01J41/13 , B01D15/36 , B01J41/20 , B01J41/04 , G01N30/96 , G01N30/00 , B01J41/05 , B01J41/07
摘要: Ion exchange stationary phases are prepared with diprimary diamines for applications such as separating samples that contain polyvalent anions. The ion exchange stationary phase includes a series of condensation polymer reaction products bound to a substrate. The condensation polymer products are formed with diprimary diamines and polyepoxide compounds. The ion exchange stationary phases described herein are capable of separating monovalent and highly polyvalent anions relatively quickly with relatively low eluent concentrations in one chromatographic run.
-
公开(公告)号:US20220339618A1
公开(公告)日:2022-10-27
申请号:US17809054
申请日:2022-06-27
申请人: DIONEX CORPORATION
发明人: Christopher A Pohl
摘要: Ion exchange stationary phases are prepared with diprimary diamines for applications such as separating samples that contain polyvalent anions. The ion exchange stationary phase includes a series of condensation polymer reaction products bound to a substrate. The condensation polymer products are formed with diprimary diamines and polyepoxide compounds. The ion exchange stationary phases described herein are capable of separating monovalent and highly polyvalent anions relatively quickly with relatively low eluent concentrations in one chromatographic run.
-
公开(公告)号:US20220184596A1
公开(公告)日:2022-06-16
申请号:US17442573
申请日:2020-03-10
发明人: Yu FUJIMURA , Takahiro KAWAKATSU , Yoichi TANAKA
IPC分类号: B01J47/014 , B01J41/14 , B01J41/13 , B01J47/127 , B01D15/36
摘要: An organic solvent treatment method for removing particulates from an organic solvent used in a manufacturing step of electronic components is characterized by comprising a step of bringing the organic solvent into contact with a treatment material that has a positive or negative electric charge in water and has a moisture content of 3% by mass or more. An organic solvent treatment material, which is to be used in the manufacturing step of electronic components and which is for removing particulates from an organic solvent by coming into contact with the organic solvent used in the manufacturing step of electronic components, has a positive or negative electric charge in water.
-
公开(公告)号:US20220033571A1
公开(公告)日:2022-02-03
申请号:US17389593
申请日:2021-07-30
IPC分类号: C08G61/02 , H01M8/1004 , C08G61/12 , B01J41/13 , H01M50/414
摘要: Embodiments in accordance with the present invention encompass a variety of polymers derived from polycyclic olefin monomers, such as hydrocarbon functionalized norbomenes. The polymers so formed function as ionomers and are suitable as anion exchange membrane for fabricating a variety of electrochemical devices, among others. More specifically, the ionomeric polymers used herein are derived from a variety of quaternized amino functionalized norbornene monomers and are lightly crosslinked (less than ten mol %). The membranes made therefrom exhibit very high ionic conductivity of up to 198 mS/cm at 80° C. This invention also relates to using an anion conducting solid polymer electrolyte as the ion conducting medium between the two electrodes and the ion conducting medium within the electrodes acting as the ionic conduit between electroactive material and electrolyte. The electrochemical devices made in accordance of this invention are useful as fuel cells, gas separators, and the like.
-
公开(公告)号:US11154852B2
公开(公告)日:2021-10-26
申请号:US16547473
申请日:2019-08-21
发明人: Kenji Miyatake , Junpei Miyake , Naoki Yokota , Katsuya Nagase , Aoi Takano , Takeshi Kato , Koichiro Asazawa
IPC分类号: B01J41/13 , H01M8/10 , B01J41/07 , B01J47/12 , C08G61/12 , H01M4/86 , H01M8/1023 , H01M8/1039 , H01M8/1018
摘要: Provided are an anion exchange resin being capable of producing an electrolyte membrane and the like, which have improved chemical properties (durability). For example, used is an anion exchange resin comprising a hydrophobic unit being composed of a plurality of divalent hydrophobic groups repeated via carbon-carbon bond, the divalent hydrophobic group having a plurality of aromatic rings which are connected to each other via a divalent fluorine-containing group; and a hydrophilic unit being composed of a plurality of hydrophilic groups repeated via carbon-carbon bond, the hydrophilic groups being composed of a plurality of aromatic rings which are connected to each other via a divalent hydrocarbon group and/or carbon-carbon bond, and the hydrophilic groups containing an anion exchange group-containing group including a quaternary ammonium salt having a piperidine ring, and wherein the hydrophobic unit and the hydrophilic unit are connected via carbon-carbon bond.
-
公开(公告)号:US20210320315A1
公开(公告)日:2021-10-14
申请号:US16789346
申请日:2020-02-12
申请人: Xergy Inc
发明人: Bamdad Bahar , Taoli Gu
IPC分类号: H01M8/1023 , H01M8/22 , H01M8/1053 , H01M8/1058 , H01M8/1051 , C08G61/10 , B01J41/13
摘要: An anion exchange polymer includes aryl ether linkage free polyarylenes having aromatic/polyaromatic rings in polymer backbone and a tethered alkyl quaternary ammonium hydroxide side groups. This anion exchange polymer may be utilized in an anion exchange process and may be made into a thin anion transfer membrane. An ion transfer membrane may be mechanically reinforced having one or more layers of functional polymer based on a terphenyl backbone with quaternary ammonium functional groups and an inert porous scaffold material for reinforcement. An anion exchange membrane may have multilayers of anion exchange polymers which each containing varying types of backbones, varying degrees of functionalization, or varying functional groups to reduce ammonia crossover through the membrane.
-
公开(公告)号:US11118274B2
公开(公告)日:2021-09-14
申请号:US16741038
申请日:2020-01-13
发明人: Tyler S. Matthews , Steven J. Hamrock , Marina M. Kaplun , Krzysztof A. Lewinski , Sean M. Luopa
摘要: Described herein is a process for the reduction of carbon dioxide comprising: providing an electrochemical device comprising an anode, a cathode, and a polymeric anion exchange membrane therebetween, wherein the polymeric anion exchange membrane comprises an anion exchange polymer, wherein the anion exchange polymer comprises at least one positively charged group selected from a guanidinium, a guanidinium derivative, an N-alkyl conjugated heterocyclic cation, or combinations thereof; introducing a composition comprising carbon dioxide to the cathode; and applying electrical energy to the electrochemical device to effect electrochemical reduction of the carbon dioxide.
-
-
-
-
-
-
-
-
-