公开(公告)号：US20250025869A1

公开(公告)日：2025-01-23

申请号：US18713695

申请日：2022-09-14

Applicant: KURITA WATER INDUSTRIES LTD.

Inventor： Takahiro KAWAKATSU ,  Yu FUJIMURA ,  Takaaki CHUUMAN

IPC: B01J41/14 ,  B01J39/07 ,  B01J41/07 ,  B01J47/014

Abstract: Provided is a material for removing impurities in an organic solvent having a water content of 1,000 ppm or less, the material comprising a porous ion exchange resin. It is preferred that the porous ion exchange resin has, as an ion exchange group, at least one functional group selected from the group consisting of a primary amino group, a secondary amino group, a tertiary amino group and a quaternary ammonium group. Also provided is a method for removing impurities in an organic solvent, the method comprising bringing the material for removing impurities in an organic solvent into contact with an organic solvent having a water content of 1,000 ppm or less.

公开(公告)号：US20240216843A1

公开(公告)日：2024-07-04

申请号：US18606529

申请日：2024-03-15

Applicant: FUJIFILM Corporation

Inventor： Tetsuya KAMIMURA ,  Masahiro YOSHIDOME ,  Yukihisa KAWADA

IPC: B01D37/04 ,  B01D19/04 ,  B01D27/00 ,  B01D39/16 ,  B01D53/46 ,  B01J31/00 ,  B01J31/06 ,  B01J47/014

CPC classification number: B01D37/04 ,  B01D19/0404 ,  B01D27/00 ,  B01D39/1676 ,  B01D53/46 ,  B01J31/00 ,  B01J31/063 ,  B01J47/014 ,  B01D2257/60

Abstract: An object of the present invention is to provide a chemical liquid purification method which makes it possible to obtain a chemical liquid having excellent defect inhibition performance. Another object of the present invention is to provide a chemical liquid. The chemical liquid purification method according to an embodiment of the present invention is a chemical liquid purification method including obtaining a chemical liquid by purifying a substance to be purified containing an organic solvent, in which a content of the stabilizer in the substance to be purified with respect to the total mass of the substance to be purified is equal to or greater than 0.1 mass ppm and less than 100 mass ppm.

公开(公告)号：US11896969B2

公开(公告)日：2024-02-13

申请号：US17012108

申请日：2020-09-04

Applicant: BIO-RAD LABORATORIES, INC.

Inventor： Christopher Belisle ,  Xuemei He ,  Hong Chen ,  Yueping Xu ,  Jiali Liao

IPC: B01J41/07 ,  B01J47/02 ,  C07K1/18 ,  C12N9/88 ,  B01J47/014 ,  B01J41/14

CPC classification number: B01J41/14 ,  B01J41/07 ,  B01J47/014 ,  B01J47/02 ,  C07K1/18 ,  C12N9/88 ,  C12Y402/01045 ,  B01J2220/52

Abstract: Chromatography resins having anionic exchange-hydrophobic mixed mode ligands and methods of using such resins are provided.

公开(公告)号：US20230158483A1

公开(公告)日：2023-05-25

申请号：US17920135

申请日：2021-04-23

Applicant: TOYOBO CO., LTD.

Inventor： Ayano Higaki ,  Hirofumi Hakuba

IPC: B01J41/16 ,  B01J41/04 ,  C08J5/22 ,  B01D69/02 ,  B01J47/014

CPC classification number: B01J41/16 ,  B01J41/04 ,  C08J5/2212 ,  B01D69/02 ,  B01J47/014 ,  B01D2325/02833 ,  B01D2325/02834 ,  B01D2325/022 ,  B01D2325/04 ,  B01D2325/16 ,  B01D2325/42 ,  C08J2301/08

Abstract: An object of the present invention is to provide an ion-exchange membrane for simply and inexpensively separating and purifying exosomes present in a biological sample such as serum. The invention relates to a cellulose-based ion-exchange membrane containing a cellulose-based polymer having at least one hydroxyl group or acetyl group at the 2-, 3-, or 6-position being replaced with a positively charged compound. The invention also relates to a method for purifying exosomes, including subjecting a sample containing exosomes to membrane permeation by using the cellulose-based ion-exchange membrane to allow for adsorption of the exosomes, bringing the membrane into contact with a washing liquid to remove impurities, and bringing the membrane into contact with an eluent to allow for desorption of the exosomes.

公开(公告)号：US20230002579A1

公开(公告)日：2023-01-05

申请号：US17822995

申请日：2022-08-29

Applicant: Trajan Scientific Australia Pty Ltd

Inventor： Hans-Jurgen WIRTH ,  Wei Boon HON

IPC: C08J9/28 ,  B01J47/014 ,  G01N1/40 ,  B01D15/32 ,  G01N1/10 ,  B01J20/285 ,  C08J9/36 ,  B01J20/32 ,  B01J41/14 ,  B01D15/36 ,  B01J20/26 ,  B01D15/38 ,  B01J39/20

Abstract: A porous polymer monolith comprises a polymer body having macroporous through-pores that facilitate fluid flow through the body and an array of mesopores adapted to bind from the fluid flow molecules of a predetermined range of sizes, wherein the surface area of the monolith is predominantly provided by the mesopores. Also disclosed is a method of making a porous polymer monolith. The method includes forming a polymer body by phase separation out of a solution containing at least a monomer, a crosslinker and a primary porogen, whereby the body contains multiple macroporous through-pores, wherein the solution further contains a secondary porogen comprising oligomers inert with respect to the monomer and cross-linker but chemically compatible with the monomer so as to form mesostructures within the polymer body during said phase separation, and washing the mesostructures from the body to provide an array of mesopores such that the surface area of the monolith is predominantly provided by the mesopores.

公开(公告)号：US11459437B1

公开(公告)日：2022-10-04

申请号：US15779241

申请日：2016-11-28

Applicant: Trajan Scientific Australia Pty Ltd

Inventor： Hans-Jurgen Wirth ,  Wei Boon Hon

IPC: C08J9/28 ,  G01N1/40 ,  C08J9/36 ,  B01J39/20 ,  B01J41/14 ,  G01N1/10 ,  B01J20/26 ,  B01J20/285 ,  B01J20/32 ,  B01D15/38 ,  B01D15/36 ,  B01D15/32 ,  B01J47/014

Abstract: A porous polymer monolith comprises a polymer body having macroporous through-pores that facilitate fluid flow through the body and an array of mesopores adapted to bind from the fluid flow molecules of a predetermined range of sizes, wherein the surface area of the monolith is predominantly provided by the mesopores. Also disclosed is a method of making a porous polymer monolith. The method includes forming a polymer body by phase separation out of a solution containing at least a monomer, a crosslinker and a primary porogen, whereby the body contains multiple macroporous through-pores, wherein the solution further contains a secondary porogen comprising oligomers inert with respect to the monomer and cross-linker but chemically compatible with the monomer so as to form mesostructures within the polymer body during said phase separation, and washing the mesostructures from the body to provide an array of mesopores such that the surface area of the monolith is predominantly provided by the mesopores.

公开(公告)号：US11305271B2

公开(公告)日：2022-04-19

申请号：US15677526

申请日：2017-08-15

Applicant: EMD Millipore Corporation

Inventor： David Yavorsky ,  John Amara ,  Joaquin Umana ,  William Cataldo ,  Mikhail Kozlov ,  Matthew Stone

IPC: B01D15/36 ,  B01J20/28 ,  B01J47/12 ,  B01J39/26 ,  C12N7/02 ,  B01J47/014 ,  B01J47/127 ,  B01D15/38 ,  C07K1/18 ,  B01J41/20 ,  B01D15/32 ,  B01J20/285 ,  B01J20/287 ,  B01J20/32 ,  C07K16/00 ,  C12N7/00 ,  G01N30/52

Abstract: Adsorptive media for chromatography, particularly ion-exchange chromatography, derived from a shaped fiber. In certain embodiments, the functionalized shaped fiber presents a fibrillated or ridged structure which greatly increases the surface area of the fibers when compared to ordinary fibers. Also disclosed herein is a method to add surface pendant functional groups that provides cation-exchange or anion-exchange functionality to the high surface area fibers. This pendant functionality is useful for the ion-exchange chromatographic purification of biomolecules, such as monoclonal antibodies (mAbs).

公开(公告)号：US11266934B2

公开(公告)日：2022-03-08

申请号：US16615426

申请日：2018-06-27

Applicant: Daikin Industries, LTD.

Inventor： Shouji Itakura ,  Ryou Hatayama ,  Mihoko Ohashi ,  Michinobu Koizumi

IPC: B01D37/02 ,  B01J47/014 ,  B01D61/02 ,  B01D61/04 ,  B01D61/14 ,  B01D61/16 ,  B01J20/14 ,  B01J20/20 ,  B01J20/28 ,  B01J41/12 ,  B01J47/02 ,  C02F9/00 ,  C08F20/04 ,  B01J39/07 ,  B01J20/10 ,  C02F1/28 ,  C02F1/42 ,  C02F1/44 ,  B01J41/05 ,  B01J39/05 ,  C02F101/30 ,  C02F103/38

Abstract: A method for treating an aqueous fluid resulting from a fluorine-containing polymer production step, the method comprising: separating the aqueous fluid into a solid component and a filtrate using a filter aid.

公开(公告)号：US20200155996A1

公开(公告)日：2020-05-21

申请号：US16635360

申请日：2018-10-16

Applicant: Mitsubishi Heavy Industries Engineering, Ltd.

Inventor： Shinichi Okamoto ,  Shinji Nakamura ,  Takuya Hirata

IPC: B01D53/14 ,  B01D53/18 ,  B01D15/38 ,  B01D15/20 ,  B01J45/00 ,  B01J47/014 ,  B01J49/50 ,  G01N1/20

Abstract: A method for recovering an acidic gas, includes: a step of bringing a gas to be treated that contains an acidic gas into gas-liquid into contact with an amine absorbing solution, allowing the amine absorbing solution to absorb the acidic gas, thereby removing the acidic gas from the gas to be treated; a step of allowing the amine absorbing solution that has absorbed the acidic gas to release the acidic gas, thereby regenerating the amine absorbing solution, and at the same time, recovering the released acidic gas; and an analysis step of calculating concentrations of iron ions and/or heavy metal ions in the amine absorbing solution.

公开(公告)号：US20190291095A1

公开(公告)日：2019-09-26

申请号：US16435515

申请日：2019-06-09

Applicant: CHONGQING BOLANYING (BLY) BIOTECHNOLOGY CO., LTD.

Inventor： Fei LIAO ,  Gaobo LONG ,  Yanling XIE ,  Mingtong HUANG ,  Wanjun XIE

IPC: B01J43/00 ,  C12N15/10 ,  C07K1/18 ,  G01N1/40 ,  C12Q1/6806 ,  B01J47/014 ,  G01N21/80

Abstract: An amphoteric dissociation ion exchange separation medium, the surface of which is an amphoteric dissociation covalently-modified layer. When an environmental pH value is lower than the isoelectric point, pIm, of the covalently-modified layer, the type of net charges on the surface of the covalently-modified layer is positive and the separation medium has the properties of an anion exchanger; when the environmental pH value is higher than the pIm, the type of net charges on the covalently-modified layer surface is negative and the separation medium has the properties of a cation exchanger. The separation medium has the properties of an anion exchanger and a cation exchanger at both sides of the pIm, respectively. The pH of an eluent can be adjusted to allow the separation medium surface and the target substance to have the same type of net charges, so that the target substance can be released by electrostatic repulsion.