公开(公告)号：US20110111429A1

公开(公告)日：2011-05-12

申请号：US12613770

申请日：2009-11-06

Applicant: Ta-Chau Chang ,  Chih-Chien Cho ,  Cheng-Chung Chang ,  Chi-Chih Kang ,  Zi-Fu Wang

Inventor： Ta-Chau Chang ,  Chih-Chien Cho ,  Cheng-Chung Chang ,  Chi-Chih Kang ,  Zi-Fu Wang

IPC: G01N33/53 ,  C07D211/68

CPC classification number: C07D401/14 ,  C09K11/06 ,  C09K2211/1029

Abstract: A compound of formula (I): in which R1-R8, A, B, X, Y, m, and n are as defined herein. Also disclosed is a method for detecting a cancer cell using a compound of formula I.

Abstract translation: 式（I）化合物：其中R 1 -R 8，A，B，X，Y，m和n如本文所定义。 还公开了使用式I化合物检测癌细胞的方法。

公开(公告)号：US07923007B2

公开(公告)日：2011-04-12

申请号：US11462426

申请日：2006-08-04

Applicant: Hung Li ,  Woei-Cherng Shyu ,  Dah-Ching Ding ,  Shin-Zong Lin

Inventor： Hung Li ,  Woei-Cherng Shyu ,  Dah-Ching Ding ,  Shin-Zong Lin

IPC: A01N63/00 ,  A01N65/00 ,  A61K48/00 ,  C12N5/071

CPC classification number: C12N5/0605 ,  A61K35/12

Abstract: A cultured pluripotent animal cell that is CD13+, CD90+, and CD117−. Also disclosed are methods for making the cell and methods of treating a brain tissue damage and increasing the expression level of a neuraltrophic factor in a subject.

Abstract translation: 培养的多能动物细胞，CD13 +，CD90 +和CD117-。 还公开了用于制备细胞的方法和治疗脑组织损伤并增加受试者中神经营养因子的表达水平的方法。

公开(公告)号：US20110010797A1

公开(公告)日：2011-01-13

申请号：US12832234

申请日：2010-07-08

Applicant: Yi-Fang Tsay ,  Shu-Chun Fan ,  Hui-Yu Chen

Inventor： Yi-Fang Tsay ,  Shu-Chun Fan ,  Hui-Yu Chen

IPC: A01H5/00 ,  C12N15/82 ,  C07K14/415 ,  C07H21/04

CPC classification number: C12N15/8243 ,  C07K14/415 ,  C12N15/8261 ,  Y02A40/146

Abstract: The present invention provides a method for changing nitrogen utilization efficiency in a plant comprises regulating the expression of Arabidopsis NRT 1.7 or an orthologue thereof so that the nitrate remobilization from older leaves to young leaves in the plant is regulated, thereby the nitrogen utilization efficiency is changed. The present invention also provides a transgenic plant obtainable by transforming a plant with an expression construct with a high or low level of expression of NRT 1.7. On the other hand, the present invention yet provides a chimera nitrate transporter, a DNA molecule coding for this chimera transporter and an expression vector thereof.

Abstract translation: 本发明提供一种改变植物氮利用效率的方法，包括调节拟南芥NRT 1.7或其直向同源物的表达，从而调节植物中从老叶到幼叶的硝酸盐再生，从而改变氮利用效率 。 本发明还提供了通过用具有高或低水平的NRT1.7表达的表达构建体转化植物可获得的转基因植物。 另一方面，本发明还提供了嵌合体硝酸盐转运蛋白，编码该嵌合体转运蛋白的DNA分子及其表达载体。

公开(公告)号：US20100323506A1

公开(公告)日：2010-12-23

申请号：US12489688

申请日：2009-06-23

Applicant: Yuh-Jen Cheng ,  Ming-Hua Lo ,  Hao-Chung Kuo

Inventor： Yuh-Jen Cheng ,  Ming-Hua Lo ,  Hao-Chung Kuo

IPC: H01L21/205

CPC classification number: H01L21/0242 ,  H01L21/02458 ,  H01L21/0254 ,  H01L21/02551 ,  H01L21/02658 ,  H01L33/007

Abstract: A method for fabricating a semiconductor layer comprising: a) growing a semiconductor layer on a foreign substrate; b) forming at least one opening on the semiconductor layer, wherein the opening exposes the interface between the semiconductor layer and the foreign substrate; and c) removing at least part of the semiconductor solid state material along the interface between the semiconductor layer and the foreign substrate. The removing step c) is preferably achieved by selective interfacial chemical etching. The semiconductor layer may be utilized as a substrate for fabrication of a wide variety of electronic and opto-electronic devices and integrated circuitry products.

Abstract translation: 一种制造半导体层的方法，包括：a）在异质衬底上生长半导体层; b）在所述半导体层上形成至少一个开口，其中所述开口暴露所述半导体层和所述异质衬底之间的界面; 以及c）沿着所述半导体层和所述异质衬底之间的界面去除所述半导体固态材料的至少一部分。 去除步骤c）优选通过选择性界面化学蚀刻来实现。 半导体层可以用作用于制造各种电子和光电子器件和集成电路产品的衬底。

公开(公告)号：US20100317603A1

公开(公告)日：2010-12-16

申请号：US12485461

申请日：2009-06-16

Applicant: Lie-Fen Shyur ,  Chia-Chung Hou ,  Jyh-Horng Wu ,  Yi-Ping Chen ,  Sheng-Yang Wang ,  Chi-Chang Huang ,  Ning-Sun Yang

Inventor： Lie-Fen Shyur ,  Chia-Chung Hou ,  Jyh-Horng Wu ,  Yi-Ping Chen ,  Sheng-Yang Wang ,  Chi-Chang Huang ,  Ning-Sun Yang

IPC: A61K31/7028 ,  A61P35/00 ,  A61P29/00

CPC classification number: A61K36/41

Abstract: Disclosed are extracts, compositions, and methods for treating cancer and inflammatory disorders. Also disclosed are methods for preparing extracts or compounds for treating the disorders.

Abstract translation: 公开了用于治疗癌症和炎性疾病的提取物，组合物和方法。 还公开了制备用于治疗疾病的提取物或化合物的方法。

公开(公告)号：US20100275986A1

公开(公告)日：2010-11-04

申请号：US12508574

申请日：2009-07-24

Applicant: Jiann Tsuen Lin ,  Yung-Sheng Yen ,  Ying-Chan Hsu ,  Ming-Chang Yeh ,  Pin-Cheng Chen

Inventor： Jiann Tsuen Lin ,  Yung-Sheng Yen ,  Ying-Chan Hsu ,  Ming-Chang Yeh ,  Pin-Cheng Chen

IPC: H01L31/0216 ,  C07D307/54

CPC classification number: H01G9/2059 ,  C07D307/54 ,  C09B57/00 ,  C09B57/008 ,  H01G9/2031 ,  H01L51/006 ,  H01L51/0061 ,  H01L51/0065 ,  H01L51/0068 ,  Y02E10/542 ,  Y02E10/549

Abstract: An organic dye used in a dye-sensitized solar cell is described, having general formula (1): wherein Ar1 represents a substituted or unsubstituted arylene group, Ar2 and Ar3 each independently represent a substituted or unsubstituted aryl group, Sp1 represent a single bond or a spacer group allowing conjugation between Ar1 and the furan moiety, Sp2 represent a single bond or a spacer group allowing conjugation between the furan moiety and Ac, Ac represents an acceptor group, and Y represents an anchoring group.

Abstract translation: 描述了用于染料敏化太阳能电池的有机染料，具有通式（1）：其中Ar 1表示取代或未取代的亚芳基，Ar 2和Ar 3各自独立地表示取代或未取代的芳基，Sp 1表示单键或 间隔基允许Ar1与呋喃部分结合，Sp2表示单键或间隔基，允许呋喃部分与Ac，Ac表示受体基团之间缀合，Y表示锚定基团。

公开(公告)号：US20100255906A1

公开(公告)日：2010-10-07

申请号：US12568782

申请日：2009-09-29

Applicant: Sheng-Wei Chen

Inventor： Sheng-Wei Chen

IPC: A63F13/00 ,  A63F9/24

CPC classification number: A63F13/63 ,  A63F13/10 ,  A63F2300/6018 ,  A63F2300/61 ,  A63F2300/634

Abstract: Some general aspects of the invention relate to approaches for generating a graphical representation of players' gaming experience. Gaming information representing player activity is first collected. The gaming information includes, for example, data obtained from a game log file characterizing a set of game events, and a set of images (e.g., comicshots associated with the game events) for use in generating the graphical representation. Images are associated with significance scores determined from at least the collected gaming information. Based on the significance scores, a set of images is selected for use in the graphical representation, and partitioned into subsets of images each subset to be presented in a respective one of one or more successive presentation units of the graphical representation. In some examples, the graphical representation can be enhanced by introducing textual annotations and/or sound effects to the images.

Abstract translation: 本发明的一些一般方面涉及用于生成玩家游戏体验的图形表示的方法。 首先收集代表玩家活动的游戏信息。 游戏信息包括例如从表征一组游戏事件的游戏日志文件获得的数据，以及用于生成图形表示的一组图像（例如与游戏事件相关联的漫画）。 图像与至少从所收集的游戏信息确定的显着性得分相关联。 基于重要性分数，选择一组图像以用于图形表示，并将其划分为图像的子集，每个子​​集将被呈现在图形表示的一个或多个连续呈现单元中的相应一个中。 在一些示例中，可以通过向图像中引入文本注释和/或声音效果来增强图形表示。

公开(公告)号：US20100247571A1

公开(公告)日：2010-09-30

申请号：US12748265

申请日：2010-03-26

Applicant: Chi-Huey Wong ,  Che Ma ,  Cheng-Chi Wang ,  Juine-Ruey CHEN

Inventor： Chi-Huey Wong ,  Che Ma ,  Cheng-Chi Wang ,  Juine-Ruey CHEN

IPC: A61K39/145 ,  C07K14/11 ,  C07K14/135 ,  C07K14/18 ,  C07K14/155 ,  A61K39/155 ,  A61K39/12 ,  A61K39/29 ,  A61K39/21 ,  C12P21/02 ,  A61P31/12 ,  A61P31/16 ,  A61P31/14 ,  A61P31/18

CPC classification number: A61K39/145 ,  A61K39/12 ,  A61K2039/55505 ,  C07K16/1018 ,  C07K2317/76 ,  C12N7/00 ,  C12N2740/11034 ,  C12N2740/16034 ,  C12N2760/16122 ,  C12N2760/16134 ,  C12N2760/16171 ,  C12N2770/24134 ,  Y02A50/386

Abstract: Immunogenic compositions comprising partially glycosylated viral glycoproteins for use as vaccines against viruses are provided. Vaccines formulated using mono-, di-, or tri-glycosylated viral surface glycoproteins and polypeptides provide potent and broad protection against viruses, even across strains. Pharmaceutical compositions comprising monoglycosylated hemagglutinin polypeptides and vaccines generated therefrom and methods of their use for prophylaxis or treatment of viral infections are disclosed. Methods and compositions are disclosed for influenza virus HA, NA and M2, RSV proteins F, G and SH, Dengue virus glycoproteins M or E, hepatitis C virus glycoprotein E1 or E2 and HIV glycoproteins gp120 and gp41.

Abstract translation: 提供了包含部分糖基化的病毒糖蛋白的免疫原性组合物，其用作抗病毒疫苗。 使用单糖，二糖或三糖基化的病毒表面糖蛋白和多肽配制的疫苗甚至可以跨毒株提供有效和广泛的防病毒保护。 公开了包含单糖基化血凝素多肽和由其产生的疫苗的药物组合物及其用于预防或治疗病毒感染的方法。 公开了用于流感病毒HA，NA和M2，RSV蛋白F，G和SH，登革病毒糖蛋白M或E，丙型肝炎病毒糖蛋白E1或E2和HIV糖蛋白gp120和gp41的方法和组合物。

公开(公告)号：US20100203582A1

公开(公告)日：2010-08-12

申请号：US12370118

申请日：2009-02-12

Applicant: Po-Huang Liang ,  Chih-Jung Kuo ,  Yan-Ping Shih

Inventor： Po-Huang Liang ,  Chih-Jung Kuo ,  Yan-Ping Shih

IPC: C12P21/00 ,  C12N9/48 ,  C12N15/74 ,  C07H21/04

CPC classification number: C12P21/06 ,  C12N9/506

Abstract: A mutated severe acute respiratory syndrome-associated coronavirus 3C-like protease and use thereof for cleaving a protein that includes a cleavage site recognizable by the mutated protease to yield a polypeptide fragment of interest.

Abstract translation: 突变的严重急性呼吸综合征相关冠状病毒3C样蛋白酶及其用于切割蛋白质的用途，所述蛋白质包括可被突变蛋白酶识别的切割位点以产生感兴趣的多肽片段。

公开(公告)号：US20100184617A1

公开(公告)日：2010-07-22

申请号：US12687044

申请日：2010-01-13

Applicant: Chung-Hsuan CHEN ,  Chen-Ren HSIAO

Inventor： Chung-Hsuan CHEN ,  Chen-Ren HSIAO

IPC: C40B30/04 ,  C40B40/00 ,  C40B40/06

CPC classification number: C40B30/04 ,  G01N33/587

Abstract: Methods for determining the quality of a biomolecular microarray to determine suitability of the microarray for performing specific binding reactions, such as hybridization, are provided. Methods are based on staining a microarray with a solution of detectable nanoparticles that reversibly stain the biomolecules through an electrostatic interaction to select microarrays that meet quality standards for hybridization reactions. A gold nanoparticle solution based staining method for DNA microarrays is provided. Destaining methods allowing multiple rounds of hybridization of nanogold stained microarrays are provided. Microarrays selected by methods of the invention are provided.

Abstract translation: 提供了用于确定生物分子微阵列的质量以确定用于进行特异性结合反应（例如杂交）的微阵列适合性的方法。 方法是基于用可检测纳米颗粒的溶液染色微阵列，其通过静电相互作用可逆地染色生物分子，以选择满足杂交反应质量标准的微阵列。 提供了一种基于金纳米颗粒溶液的DNA微阵列染色方法。 提供了允许纳米金染色的微阵列进行多轮杂交的脱色方法。 提供了通过本发明的方法选择的微阵列。