Abstract:
A self healing high energy glass capacitor is provided. The capacitor can have a glass layer with a top surface and a bottom surface. A top sacrificial layer can extend across the top surface and a bottom sacrificial layer can extend across the bottom surface. In addition, a top electrode can extend across the top sacrificial layer and a bottom electrode can extend across the bottom sacrificial layer. In some instances the glass capacitor has an energy breakdown of at least 6 joules per cubic centimeter.
Abstract:
Generally described, the present disclosure relates to footwear. More specifically, this disclosure relates to a shoelace protector and methods thereof. In one illustrative embodiment, the shoelace protector can include a fastening member, enclosure and upper section. The fastening member can be inserted into to an eyelet of a shoe to properly support the shoelace protector. The shoelace can be strung into the fastening member and through the enclosure. The enclosure can surround the shoe lace on an exterior portion of the shoe. The shoelace can then be placed through the upper section. The upper section can provide a narrow slit such that the shoelace can be fit therethrough. One or more shoelace protectors can be fitted into the eyelets of the shoe. The protectors can be positioned on the lower eyelets such that the bend created by the eyelet on the shoelace can be protected during use.
Abstract:
This disclosure relates to a shoelace protector and methods thereof. In one shoelace protector, as disclosed herein, enclosure can be coupled to the eyelet and the upper section of the shoe. Instead, of using the fastening member to secure those components, eyelets can be incorporated with those features. The eyelets having the additional appendages can be incorporated when the shoe is manufactured or during use. The shoelace can be strung into the eyelet and through the bottom portion of the protector connecting with the eyelet. A top portion of the protector can surround the shoe lace on an exterior portion of the shoe. The shoelace can then be placed through the protector. In another embodiment, the protector does not have to be attached to the eyelet, but can be coupled to the vamp sections of the shoes removing the need for the fastening member.
Abstract:
Disclosed herein are carbonyl compounds of Formula: (I) as described herein. Compounds as modulators of his-tone deacetylase (HDAC), pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
Abstract:
The present invention relates to a compound of the following formula: or a pharmaceutically acceptable salt thereof. Also disclosed are compositions containing the compound and methods of preparing and using the compounds. The compounds of the invention are useful in treating αLβ2 adhesion mediated conditions in a mammal.
Abstract translation:本发明涉及下式的化合物或其药学上可接受的盐。 还公开了含有该化合物的组合物和制备和使用该化合物的方法。 本发明的化合物可用于治疗哺乳动物中的α2 L 2β2/2粘附介导的病症。
Abstract:
Pyrrole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, bipolar disorder and panic, as well as in the treatment of pain, circadian rhythm disorders, and other diseases.
Abstract:
In accordance with the present invention, there is provided a novel class of heterocyclic compounds. Compounds of the invention contain a substituted, unsaturated five, six or seven membered heterocyclic ring that includes at least one nitrogen atom and at least one carbon atom. The ring additionally includes three, four or five atoms independently selected from carbon, nitrogen, sulfur and oxygen atoms. The heterocyclic ring has at least one substituent located at a ring position adjacent to a ring nitrogen atom. This mandatory substituent of the ring includes a moiety (B), linked to the heterocyclic ring via a carbon-carbon double bond, a carbon-carbon triple bond or an azo group. The mandatory substituent is positioned adjacent to the ring nitrogen atom. Invention compounds are capable of a wide variety of uses. For example heterocyclic compounds can act to modulate physiological processes by functioning as agonists and antagonists of receptors in the nervous system. Invention compounds may also act as insecticides, and as fungicides. Pharmaceutical compositions containing invention compounds also have wide utility.
Abstract:
The present invention relates to a device for delivering a supply of gases to a patient. The device includes a patient interface and connecting member. The connecting member is preferably a L-shaped swivelled connector that is capable of being fixed into one of two positions, a first position where the connector is freely rotatable within the patient interface, and a second position where an interference between the interface and connector prevents the free rotation of the connector within the patient interface. The present invention further relates to a connector that has outlet means, which includes at least one outlet vent and a funnel, which in use directs and passes a substantial portion gases expired from the patient through the outlet vent or vents.
Abstract:
The present invention relates to small molecules according to formula (I) that are potent inhibitors of &agr;L&bgr;2 mediated cell adhesion and which could be useful for the treatment of inflammatory diseases:
Abstract:
A filter assembly for collecting material that is entrained in a gas stream includes a housing having inlet and outlet ports for the gas that is to be filtered. The housing includes an end cap in which at least one of the ports is provided, and a body section in which a tubular filter can be located arranged for the gas stream to flow through its wall provided by a filter medium, the end cap and the body section being separable to allow access to the inside of the housing. A tubular member, which might be a filter element or a conduit for directing a flow of gas to a filter element, can be sealingly connected to the end cap in fluid communication with one of the ports therein. The tubular member includes a tang which can be received in a recess in the housing when the tubular member and the housing end cap are properly assembled.