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322 条记录 (耗时 0.043 秒)

    Chalcone compound
    41.
    发明授权
    Chalcone compound 失效
    查耳酮化合物

    公开(公告)号：US07361774B2

    公开(公告)日：2008-04-22

    申请号：US10529859

    申请日：2003-09-29

    申请人： Hiromu Ohnogi ,  Katsumi Sugiyama ,  Nobuko Muraki ,  Tatsuji Enoki ,  Hiroaki Sagawa ,  Ikunoshin Kato

    发明人： Hiromu Ohnogi ,  Katsumi Sugiyama ,  Nobuko Muraki ,  Tatsuji Enoki ,  Hiroaki Sagawa ,  Ikunoshin Kato

    IPC分类号： C07D311/82 ,  C07D311/00 ,  A01N43/16

    CPC分类号： C07D311/80 ,  A23K20/121 ,  A23L33/10 ,  C07D311/58

    摘要： The present invention relates to a chalcone compound represented by the following general formula: wherein R1 and R2 are taken together with the carbon atom to which they are bound, respectively, to form a hydroxydimethyl hexane ring, or where R1 is a hydroxyl group, R2 is an isohexenyl group, a derivative thereof, or a salt thereof. Also, the present invention relates to a therapeutic agent or prophylactic agent for a disease requiring neuronal protection, suppression for nitrogen monoxide (NO) production, inhibition for aldose reductase or suppression for interleukin production, and a food, beverage or feed for treatment or prevention of the above-mentioned disease, characterized in that each comprises the above-mentioned compound as an effective ingredient.

    摘要翻译： 本发明涉及由下列通式表示的查尔酮化合物：其中R 1和R 2分别与它们所连接的碳原子一起取代， 形成羟基二甲基己烷环，或其中R 1是羟基，R 2是异己烯基，其衍生物或其盐。 此外，本发明涉及需要神经元保护，抑制一氧化氮（NO）产生，抑制醛糖还原酶或抑制白介素产生的疾病的治疗剂或预防剂，以及用于治疗或预防的食品，饮料或饲料 的上述疾病，其特征在于，每种都包含上述化合物作为有效成分。

    Isothermal chimeric primer nucleic acid amplification methods using blocking oglionucleotide
    45.
    发明授权
    Isothermal chimeric primer nucleic acid amplification methods using blocking oglionucleotide 失效
    等温嵌合引物核酸扩增方法使用阻断寡核苷酸

    公开(公告)号：US07056671B2

    公开(公告)日：2006-06-06

    申请号：US10486645

    申请日：2002-08-20

    申请人： Tatsuji Enoki ,  Hiroaki Sagawa ,  Ikunoshin Kato

    发明人： Tatsuji Enoki ,  Hiroaki Sagawa ,  Ikunoshin Kato

    IPC分类号： C12Q1/68 ,  C12P19/34

    CPC分类号： C12Q1/6844 ,  C12Q1/6853 ,  C12Q2600/156 ,  C12Q2525/186 ,  C12Q2521/301 ,  C12Q2531/119 ,  C12Q2525/117 ,  C12Q2525/113

    摘要： Methods of amplifying a target nucleic acid whereby the target nucleic acid is amplified in the presence of a deoxyribonucleotide triphosphate, a DNA polymerase having strand displacement activity, at least one chimeric oligonucleotide primer, at least one upstream block oligonucleotide and a RNase H; wherein the chimeric oligonucleotide primer contains a ribonucleotide positioned at the 3′-terminus; wherein the upstream block oligonucleotide is capable of annealing to a region 3′ to a portion in the nucleic acid as the template to which the chimeric oligonucleotide primer anneals; and compositions and kits thereof.

    摘要翻译： 在脱氧核糖核苷酸三磷酸，具有链置换活性的DNA聚合酶，至少一种嵌合寡核苷酸引物，至少一个上游嵌段寡核苷酸和RNase H的存在下扩增靶核酸的扩增靶核酸的方法; 其中所述嵌合寡核苷酸引物含有位于3'末端的核糖核苷酸; 其中所述上游嵌段寡核苷酸能够退火至所述核酸的部分区域3'作为所述嵌合寡核苷酸引物退火的模板; 及其组合物和试剂盒。

    Remedy
    46.
    发明申请
    Remedy 审中-公开
    补救

    公开(公告)号：US20060034949A1

    公开(公告)日：2006-02-16

    申请号：US10524015

    申请日：2003-08-06

    申请人： Tatsuji Enoki ,  Kinuko Ogawa ,  Hiromu Ohnogi ,  Katsumi Sugiyama ,  Nobuko Muraki ,  Hiroaki Sagawa ,  Ikunoshin Kato

    发明人： Tatsuji Enoki ,  Kinuko Ogawa ,  Hiromu Ohnogi ,  Katsumi Sugiyama ,  Nobuko Muraki ,  Hiroaki Sagawa ,  Ikunoshin Kato

    IPC分类号： A61K36/232

    CPC分类号： A61K36/232 ,  A23L2/52 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/328 ,  A23V2250/21

    摘要： The present invention relates to a therapeutic agent or prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an insulin-mimetic action agent, a food, beverage, or feed for treating or preventing a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for enhancement of glucose uptake into a cell, and an agent for induction of an adipocyte differentiation, each comprising as an effective ingredient a processed product derived from a plant belonging to Umbelliferae.

    摘要翻译： 本发明涉及一种伴随胰岛素或胰岛素反应量异常的疾病的治疗剂或预防剂，用于治疗或预防伴随异常的疾病的胰岛素模拟作用剂，食品，饮料或饲料 一定量的胰岛素或胰岛素反应，用于增强葡萄糖摄入细胞的药剂和用于诱导脂肪细胞分化的药剂，其各自包含衍生自属于伞形属植物的植物的加工产品作为有效成分。