公开(公告)号：US20100233240A1

公开(公告)日：2010-09-16

申请号：US12161433

申请日：2007-01-18

申请人： Noriko Koizumi ,  Shigeru Kinoshita ,  Yuji Sakamoto

发明人： Noriko Koizumi ,  Shigeru Kinoshita ,  Yuji Sakamoto

IPC分类号： A61F2/14 ,  A61K35/44 ,  A61P27/02

CPC分类号： A61L27/3839 ,  A61L27/24 ,  A61L27/3808 ,  A61L2430/16

摘要： The present invention provides a graft more suitable for the transplantation of corneal endothelial cells and an application method thereof. Specifically, the present invention provides a corneal endothelial preparation capable of cell proliferation in vivo, which contains a substrate and a corneal endothelial cell layer cultured on the substrate, and a treatment method of a disease selected from the group consisting of bullous keratopathy, corneal edema, corneal leukoma and corneal endothelial inflammation, which includes a step of transplanting the preparation to patients. As the substrate, collagen is used.

摘要翻译： 本发明提供了更适合于角膜内皮细胞移植的移植物及其应用方法。 具体地说，本发明提供能够在体内进行细胞增殖的角膜内皮制剂，该角膜内皮制剂含有在底物上培养的底物和角膜内皮细胞层，以及选自下组的疾病的治疗方法：大疱性角膜病，角膜水肿 ，角膜白血病和角膜内皮炎症，其中包括将制剂移植到患者中的步骤。 作为底物，使用胶原。

公开(公告)号：US20080240474A1

公开(公告)日：2008-10-02

申请号：US10593745

申请日：2005-03-09

申请人： Yuji Sakamoto ,  Kenji Morita ,  Yoshiya Nonaka

发明人： Yuji Sakamoto ,  Kenji Morita ,  Yoshiya Nonaka

IPC分类号： H04R5/02

CPC分类号： H04R5/02 ,  H04R2205/024 ,  H04S7/302

摘要： The present invention provides an audio output apparatus, an audio signal output adjusting method, an audio signal output adjusting process program, and the like capable of preventing the user (listener) from making a complicated sound field setting even in the case where the position of a center speaker is changed.An audio output apparatus having: at least one first speaker changeably installed in a predetermined position and outputting an audio signal; and a plurality of second speakers fixedly installed in positions different from the position of the first speaker and different from each other, and outputting audio signals, the apparatus generating a sound field according to position relations among the install position of the first speaker and the install positions of the plurality of second speakers when the position of the user is used as a reference, wherein the apparatus comprises: a plurality of audio signal detecting means provided in or near the install positions of the second speakers and detecting audio signals output from the first speaker; speaker position calculating means for obtaining the audio signals detected by the audio signal detecting means, detecting that the install position of the first speaker has been changed on the basis of the obtained audio signals, and calculating the changed install position; and audio signal output adjusting means, on the basis of the changed install position of the first speaker and the install positions of the plurality of second speakers, that adjusts output of the audio signal from at least one of the first speaker whose install position has been changed and the plurality of second speakers so that a sound field according to the position relations before the install position of the first speaker was changed is maintained.

摘要翻译： 本发明提供一种能够防止使用者（听众）在复杂的声场设定的情况下即使在以下情况下也能够进行复杂的声场设定的音频输出装置，音频信号输出调整方法，音频信号输出调整处理程序等 中心扬声器已更改。 一种音频输出设备，具有：至少一个第一扬声器，其可变地安装在预定位置并输出音频信号; 以及多个固定地安装在与第一扬声器的位置不同的位置并彼此不同的位置的第二扬声器，并且输出音频信号，该装置根据第一扬声器的安装位置和安装之间的位置关系产生声场 当用户的位置用作参考时，多个第二扬声器的位置，其中该装置包括：多个音频信号检测装置，设置在第二扬声器的安装位置中或附近，并且检测从第一扬声器输出的音频信号 扬声器; 扬声器位置计算装置，用于获取由音频信号检测装置检测到的音频信号，根据获得的音频信号检测第一扬声器的安装位置是否已经改变，并且计算改变的安装位置; 以及音频信号输出调节装置，其基于第一扬声器的改变的安装位置和多个第二扬声器的安装位置，其调整来自安装位置的第一扬声器中的至少一个的音频信号的输出 改变了多个第二扬声器，从而保持了根据第一扬声器的安装位置之前的位置关系改变的声场。

公开(公告)号：US20050251618A1

公开(公告)日：2005-11-10

申请号：US11108833

申请日：2005-04-19

申请人： Yoshiya Nonaka ,  Nobuo Tarui ,  Akihiro Denda ,  Yuji Sakamoto ,  Noritaka Nii

发明人： Yoshiya Nonaka ,  Nobuo Tarui ,  Akihiro Denda ,  Yuji Sakamoto ,  Noritaka Nii

IPC分类号： G11C16/02 ,  G06F12/00 ,  G06F12/02

CPC分类号： G06F11/1441 ,  G06F12/0246 ,  G11C16/06

摘要： Data is stored in a non-volatile memory such as a flash memory. The non-volatile memory has two memory areas. When power of a device is turned on, data in the two memory areas are compared to determine which memory area includes old data, and the old data is erased. When the power is turned off, a control setting of the device used immediately before the power is turned off is stored as new data in the memory area from which the old data is erased. When the power is applied again, the new data is read, and the control setting is restored in the device.

摘要翻译： 数据存储在诸如闪存之类的非易失性存储器中。 非易失性存储器具有两个存储区域。 当打开设备的电源时，比较两个存储区域中的数据以确定哪个存储器区域包括旧数据，并且旧的数据被擦除。 当电源关闭时，在电源关闭之前使用的设备的控制设置作为新数据被存储在旧数据被擦除的存储区域中。 再次施加电源时，读取新数据，并在设备中恢复控制设置。

公开(公告)号：US20050237418A1

公开(公告)日：2005-10-27

申请号：US10519779

申请日：2003-06-27

申请人： Yuji Sakamoto

发明人： Yuji Sakamoto

IPC分类号： G02B7/02 ,  H04N5/225

CPC分类号： G02B7/026 ,  H01L2224/48091 ,  H04N5/2254 ,  H01L2924/00014

摘要： An image sensor module (X1) includes a housing (1), a lens retainer (2), an image sensor chip (4), a substrate (5) and a lens unit (A, B). The housing (1) is formed with a step portion (1a) for fixing the lens unit (A, B). The lens retainer (2) is fixed to the housing (1) and held in contact with the upper face of the lens unit (A, B). The lens unit (A, B) is pressed against the step portion (1a) of the housing (1) by a biasing force of the lens retainer (2).

摘要翻译： 图像传感器模块（X 1）包括壳体（1），透镜保持器（2），图像传感器芯片（4），基板（5）和透镜单元（A，B）。 壳体（1）形成有用于固定透镜单元（A，B）的台阶部分（1a）。 透镜保持架（2）固定在壳体（1）上并保持与透镜单元（A，B）的上表面接触。 透镜单元（A，B）通过透镜保持器（2）的偏压力被压靠在壳体（1）的台阶部分（1a）上。

公开(公告)号：US5221641A

公开(公告)日：1993-06-22

申请号：US888509

申请日：1992-05-27

申请人： Yoshio Kurita ,  Yuji Sakamoto ,  Atsushi Imai

发明人： Yoshio Kurita ,  Yuji Sakamoto ,  Atsushi Imai

IPC分类号： H01L33/52 ,  H01L33/62

CPC分类号： H01L33/62 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2924/01078 ,  H01L2924/12041 ,  H01L33/52

摘要： A process is provided for making light emitting diodes by using wire segments each plated with a glossy metal. The process comprises the steps of bending each wire segment generally into a U-shape to have a pair of legs connected together by an integral connecting web, deforming the free end of one leg by transverse compression to provide a cup end, mounting a semiconductor chip in the cup end, connecting the semiconductor chip to the free end of the other leg through a wire, forming a transparent or semitransparent resin package to enclose the respective free ends of the paired legs, and cutting the connecting web off the wire segment.

公开(公告)号：US4933122A

公开(公告)日：1990-06-12

申请号：US155248

申请日：1988-02-12

申请人： Akira Suzuki ,  Yuji Sakamoto

发明人： Akira Suzuki ,  Yuji Sakamoto

IPC分类号： A01C1/00 ,  B01J2/08 ,  C12M1/00 ,  C12M1/40 ,  C12N11/04 ,  C12N11/10

CPC分类号： B01J2/08 ,  C12N11/04

摘要： Bead producing process and an apparatus in which sol having enzymes, plant tissues, etc. dispersed therein is dropped into a solidifying liquid through a perforated plate. The sol is fed from a sol supply tank to a position near of the outer periphery of the planet gear of a planetary gear mechanism which is disposed on the perforated plate. At this moment, the sol supply tank is raised at a given rate in proportion to a decrease in the liquid level thereof so that the liquid level of the sol in the sol supply tank may be kept constant with respect to the perforated plate.

摘要翻译： 珠生产方法和其中分散有酶，植物组织等的溶胶通过多孔板滴入凝固液中的装置。 溶胶从溶胶供应罐供给到设置在多孔板上的行星齿轮机构的行星齿轮的外周附近的位置。 此时，溶胶供给罐以与其液面的降低成比例的给定速率升高，使得溶胶供应罐中的溶胶的液面可以相对于多孔板保持恒定。

公开(公告)号：US08895508B2

公开(公告)日：2014-11-25

申请号：US13386844

申请日：2009-07-24

申请人： Yasuhiko Tabata ,  Shigeru Kinoshita ,  Noriko Koizumi ,  Yuji Sakamoto ,  Naoki Okumura ,  Hiroaki Takahashi

发明人： Yasuhiko Tabata ,  Shigeru Kinoshita ,  Noriko Koizumi ,  Yuji Sakamoto ,  Naoki Okumura ,  Hiroaki Takahashi

IPC分类号： A61K38/18 ,  A61K9/00 ,  A61K9/06 ,  A61K47/42

CPC分类号： A61K38/1825 ,  A61K9/0048 ,  A61K9/06 ,  A61K47/42

摘要： The present invention aims to provide a corneal endothelium cell proliferation accelerator and a therapeutic agent for a disease relating to corneal endothelium damage, which are administered into the anterior chamber. bFGF is released in a sustained manner by forming bFGF sustained-release gelatin hydrogel particles wherein bFGF is carried on gelatin hydrogel. Therefore, the proliferation of corneal endothelium cells can be accelerated persistently by administration of a preparation containing the bFGF sustained-release gelatin hydrogel particles into the anterior chamber, and diseases relating to corneal endothelium damage can be treated.

摘要翻译： 本发明的目的在于提供角膜内皮细胞增殖促进剂和与角膜内皮损伤相关的疾病的治疗剂，其被施用于前房。 通过形成bFGF缓释明胶水凝胶颗粒，其中bFGF携带在明胶水凝胶上，以持续的方式释放bFGF。 因此，可以通过将含有bFGF缓释明胶水凝胶颗粒的制剂给予前房来持续加速角膜内皮细胞的增殖，并且可以治疗与角膜内皮损伤有关的疾病。

公开(公告)号：US08343043B2

公开(公告)日：2013-01-01

申请号：US13084055

申请日：2011-04-11

申请人： Seigo Kase ,  Yasuhito Kura ,  Yuji Sakamoto

发明人： Seigo Kase ,  Yasuhito Kura ,  Yuji Sakamoto

IPC分类号： A61B1/06

CPC分类号： A61B1/00181 ,  A61B1/00045 ,  A61B1/00096 ,  A61B1/00114 ,  A61B1/00117 ,  A61B1/00177 ,  A61B1/0052 ,  A61B1/015 ,  A61B1/04 ,  A61B1/0615 ,  A61B1/0623 ,  A61B1/0676 ,  A61B1/07 ,  A61B1/126

摘要： An endoscope includes: a distal end portion provided at a distal end of an insertion portion; a front-view observation window for observing an insertion direction of the distal end portion, which is provided facing toward the insertion direction; a lateral-view observation window for observing a circumferential direction of the distal end portion, which is formed along the outer circumferential lateral surface and has a lateral observation field of view; a light-emitting member having an emission end surface for emitting light in a distal end direction of the distal end portion; a groove portion formed on the outer circumferential lateral surface of the distal end portion so as to be longer than the emission end surface of the light-emitting member along the circumferential direction of the outer circumferential lateral surface of the distal end portion and opposed to the emission end surface, on a proximal end side with respect to the lateral-view observation window; a plurality of particles for scattering light arranged in the groove portion; and a transparent infill filled between the plurality of particles.

公开(公告)号：US20110208000A1

公开(公告)日：2011-08-25

申请号：US12899697

申请日：2010-10-07

申请人： Kazuki Honda ,  Wataru Matsuura ,  Yasuhito Kura ,  Yuji Sakamoto

发明人： Kazuki Honda ,  Wataru Matsuura ,  Yasuhito Kura ,  Yuji Sakamoto

IPC分类号： A61B1/00

CPC分类号： A61B1/0052 ,  A61B1/00016 ,  A61B1/00039 ,  A61B1/00154 ,  A61B1/0016 ,  A61B18/1492 ,  A61B34/20 ,  A61B2090/064

摘要： A medical system includes: a first operation apparatus used when a first doctor operates a medical instrument; a second operation apparatus that outputs a control instruction signal for controlling a motion of the medical instrument, and is operated by a second doctor; at least one medical action information detection section that detects medical action information based on the motion of the medical instrument when the first doctor operates the medical instrument using the first operation apparatus; a storage apparatus that stores reference information set by the second doctor according to the first doctor for comparing with the medical action information detected by the medical action information detection section; a switching signal generation apparatus that is connected to the second operation apparatus, and switches an output destination of the control instruction signal based on the medical action information detected by the medical action information detection section and the reference information stored in the storage apparatus; and a medical instrument control apparatus that controls the medical instrument according to the control instruction signal of the second operation apparatus outputted from the switching signal generation apparatus.

摘要翻译： 医疗系统包括：当第一医生操作医疗器械时使用的第一操作装置; 输出用于控制医疗器具的运动的控制指示信号并由第二医生操作的第二操作装置; 至少一个医疗动作信息检测部，其在所述第一医生使用所述第一操作装置操作所述医疗器械时，基于所述医疗器械的运动来检测医疗动作信息; 存储装置，存储由第一医生根据第一医生设定的参考信息，与医疗动作信息检测部检测出的医疗动作信息进行比较; 切换信号生成装置，其与第二运算装置连接，根据由医疗动作信息检测部检测出的医疗动作信息和存储在存储装置中的参考信息，切换控制指示信号的输出目的地; 以及医疗仪器控制装置，其根据从切换信号生成装置输出的第二运算装置的控制指示信号来控制医疗器械。

公开(公告)号：US07516283B2

公开(公告)日：2009-04-07

申请号：US11108833

申请日：2005-04-19

申请人： Yoshiya Nonaka ,  Nobuo Tarui ,  Akihiro Denda ,  Yuji Sakamoto ,  Noritaka Nii

发明人： Yoshiya Nonaka ,  Nobuo Tarui ,  Akihiro Denda ,  Yuji Sakamoto ,  Noritaka Nii

IPC分类号： G06F12/00

CPC分类号： G06F11/1441 ,  G06F12/0246 ,  G11C16/06

摘要： Data is stored in a non-volatile memory such as a flash memory. The non-volatile memory has two memory areas. When power of a device is turned on, data in the two memory areas are compared to determine which memory area includes old data, and the old data is erased. When the power is turned off, a control setting of the device used immediately before the power is turned off is stored as new data in the memory area from which the old data is erased. When the power is applied again, the new data is read, and the control setting is restored in the device.

摘要翻译： 数据存储在诸如闪存之类的非易失性存储器中。 非易失性存储器具有两个存储区域。 当打开设备的电源时，比较两个存储区域中的数据以确定哪个存储器区域包括旧数据，并且旧的数据被擦除。 当电源关闭时，在电源关闭之前使用的设备的控制设置作为新数据被存储在旧数据被擦除的存储区域中。 再次施加电源时，读取新数据，并在设备中恢复控制设置。