公开(公告)号：US3719183A

公开(公告)日：1973-03-06

申请号：US3719183D

申请日：1970-03-05

申请人： SCHWARTZ H

发明人： SCHWARTZ H

IPC分类号： A61B5/00 ,  A61B5/07 ,  A61F2/02

CPC分类号： A61B5/0031 ,  A61B5/073 ,  A61B5/425 ,  A61F2250/0002

摘要： A process for determining internal blockage to pancreatic enzyme flow in which an electronic capsule transponder has an insulative coating of material dissolvable by the action of predetermined enzyme secretions. When the coating is dissolved, the transponder is coated with the enzyme flow. The transponder may be swallowed and a stimulant may be applied to the body to selectively increase enzyme secretions.

摘要翻译： 用于确定胰酶的内部阻塞的方法，其中电子胶囊转发器具有可通过预定的酶分泌物的作用而溶解的材料的绝缘涂层。 当涂层溶解时，应答器用酶流包被。 应答器可能被吞咽，并且兴奋剂可以施用于身体以选择性地增加酶分泌。

公开(公告)号：US12121339B2

公开(公告)日：2024-10-22

申请号：US15747202

申请日：2016-06-09

申请人： Northeastern University

发明人： Codi Gharagouzloo ,  Srinivas Sridhar

IPC分类号： A61B5/055 ,  A61B5/00 ,  G01R33/48 ,  G01R33/56 ,  G01R33/563

CPC分类号： A61B5/055 ,  A61B5/4064 ,  G01R33/4816 ,  G01R33/5601 ,  G01R33/5635 ,  G01R33/56366 ,  A61B5/4088 ,  A61B5/4244 ,  A61B5/425 ,  A61B5/4866 ,  A61B2576/026

摘要： A quantitative, ultrashort time to echo, contrast-enhanced magnetic resonance imaging technique is provided. The technique can be used to accurately measure contrast agent concentration in the blood, to provide clear, high-definition angiograms, and to measure absolute quantities of cerebral blood volume on a voxel-by-voxel basis.

公开(公告)号：US12106473B2

公开(公告)日：2024-10-01

申请号：US17507949

申请日：2021-10-22

申请人： National Taiwan University

发明人： Wei-Chung Wang ,  Wei-Chih Liao ,  Kao-Lang Liu ,  Po-Ting Chen ,  Po-Chuan Wang ,  Da-Wei Chang

IPC分类号： G06T7/00 ,  A61B5/00 ,  G06N3/08 ,  G06T7/70 ,  G06T7/73 ,  G06V10/774 ,  G06V10/776 ,  G06V10/82 ,  G16H30/20

CPC分类号： G06T7/0012 ,  A61B5/425 ,  A61B5/4887 ,  A61B5/726 ,  A61B5/7267 ,  G06N3/08 ,  G06T7/70 ,  G06T7/73 ,  G06V10/774 ,  G06V10/776 ,  G06V10/82 ,  G16H30/20 ,  G06T2207/20016 ,  G06T2207/20064 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30096 ,  G06T2207/30204 ,  G06V2201/031

摘要： A medical image analyzing system and a medical image analyzing method are provided and include inputting at least one patient image into a first model of a neural network module to obtain a result having determined positions and ranges of an organ and a tumor of the patient image; inputting the result into a second model of a first analysis module and a third model of a second analysis module, respectively, to obtain at least one first prediction value and at least one second prediction value corresponding to the patient image; and outputting a determined result based on the first prediction value and the second prediction value. Further, processes between the first model, the second model and the third model can be automated, thereby improving identification rate of pancreatic cancer.

公开(公告)号：US11967084B2

公开(公告)日：2024-04-23

申请号：US17195908

申请日：2021-03-09

申请人： Ping An Technology (Shenzhen) Co., Ltd.

发明人： Ling Zhang

IPC分类号： G06T7/174 ,  A61B5/00 ,  G06T7/11 ,  G16H30/40

CPC分类号： G06T7/174 ,  A61B5/425 ,  G06T7/11 ,  G16H30/40 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/20081 ,  G06T2207/20221 ,  G06T2207/30096

摘要： A Pancreatic Ductal Adenocarcinoma (PDAC) image segmentation method, an electronic device, and a storage medium are provided. In the PDAC image segmentation method, a first model is trained using a first data set; and a second model is trained using a second data set. A third data set is obtained by annotating a to-be-annotated data set using the first model and the second model and a third model is trained using a fourth data set. A training set is obtained by modifying the first data set and the third data set using the third model and a segmentation model is obtained by training an nnUNet using the training set. A to-be-segmented PDAC image is input into the segmentation model, and a segmentation result is obtained. By utilizing the PDAC image segmentation method, a more accurate PDAC image segmentation is achieved.

公开(公告)号：US09962113B2

公开(公告)日：2018-05-08

申请号：US13521724

申请日：2011-01-12

申请人： Jochen Lang ,  Bogdan Catargi ,  Sylvie Renaud ,  Matthieu Raoux ,  Gilles Charpentier

发明人： Jochen Lang ,  Bogdan Catargi ,  Sylvie Renaud ,  Matthieu Raoux ,  Gilles Charpentier

IPC分类号： A61B5/04 ,  A61M5/172 ,  A61B5/145 ,  A61B5/00 ,  A61M5/142

CPC分类号： A61B5/14532 ,  A61B5/425 ,  A61B5/6848 ,  A61B5/685 ,  A61B2562/0209 ,  A61B2562/028 ,  A61B2562/125 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2005/1726 ,  A61M2230/201

摘要： The invention relates to a sensor (2) including: a microelectrode assembly (21); and β-pancreatic cells (23) or islets (230) of Langerhans in culture on the microelectrode assembly (21); characterized in that the microelectrode assembly (21) is designed to measure dynamically, continuously and in real time, electrical signals (V) produced by the β-pancreatic cells (23) or the islets of Langerhans (230) upon physiological activation. The invention also relates to the field of devices that can be implantable in the body of a patient, and including an insulin dispenser for dispensing an amount of insulin. The invention also relates to a method for manufacturing such a sensor and to such a device and a use of such a sensor.

公开(公告)号：US20180055408A1

公开(公告)日：2018-03-01

申请号：US15691119

申请日：2017-08-30

申请人： Washington University

发明人： Sheng-Kwei Song ,  Zezhong Ye ,  William Spees ,  Tsen-Hsuan Lin

IPC分类号： A61B5/055 ,  G01R33/563 ,  G01R33/56 ,  A61B5/00 ,  A61B10/02 ,  A61B5/20 ,  A61B10/00 ,  G06T7/00

CPC分类号： A61B5/055 ,  A61B5/0042 ,  A61B5/0044 ,  A61B5/201 ,  A61B5/202 ,  A61B5/4041 ,  A61B5/425 ,  A61B5/4312 ,  A61B5/4331 ,  A61B5/4381 ,  A61B5/7267 ,  A61B10/0041 ,  A61B10/0241 ,  A61B2010/045 ,  A61B2576/023 ,  A61B2576/026 ,  G01R33/5602 ,  G01R33/5608 ,  G01R33/56341 ,  G06K9/00127 ,  G06K9/00147 ,  G06K9/00201 ,  G06K9/6256 ,  G06T7/0012 ,  G06T2207/10088 ,  G06T2207/10092 ,  G06T2207/20081 ,  G06T2207/30016 ,  G06T2207/30024 ,  G06T2207/30048 ,  G06T2207/30081 ,  G06T2207/30096

摘要： D-Histo, a non-invasive diagnostic method, renovated from diffusion basis spectrum imaging (DBSI) is provided for quantitatively detecting and distinguishing inflammation from solid tumors, heart and nerve injury. For example, the D-Histo methods disclosed herein provide an accurate diagnosis of prostate cancer, distinguishing it from prostatitis and BPH that missed by currently available methods of diagnosing prostate cancer (multiparameter MRI, needle biopsy). The disclosed D-Histo method also provides metrics to reflect reversible vs. irreversible damages in heart and central/peripheral nerves. For central and peripheral nerves, D-Histo also provides metrics to assess nerve functionality. The at least one D-Histo biomarker obtained using diffusion weighted MRI has excellent test-retest stability, high sensitivity to disease progression and close correlation with currently available techniques.

公开(公告)号：US20170239484A1

公开(公告)日：2017-08-24

申请号：US15438976

申请日：2017-02-22

申请人： Verily Life Sciences LLC

发明人： ANIL KUMAR RAM RAKHYANI ,  Peng Cong ,  Stephen O'Driscoll ,  Sean Korhummel ,  Travis Deyle

IPC分类号： A61N1/372 ,  A61N1/378 ,  A61N1/05 ,  A61N1/36

CPC分类号： A61N1/37205 ,  A61B5/04001 ,  A61B5/14532 ,  A61B5/4227 ,  A61B5/4244 ,  A61B5/425 ,  A61B5/4255 ,  A61N1/0551 ,  A61N1/0556 ,  A61N1/36007 ,  A61N1/3606 ,  A61N1/36139 ,  A61N1/37217 ,  A61N1/37223 ,  A61N1/37288 ,  A61N1/3787

摘要： Systems and methods are provided for neuro stimulation. In one implementation, a system is provided that includes a stimulator introduced into tissue at a target location and a central controller that communicates wirelessly with the stimulator. The stimulator includes a power system that receives wireless energy transmission, and an electrode system that transmits an electrical pulse for stimulating the target location. The central controller includes a power system that wirelessly delivers power to the stimulator, a communication system that wirelessly communicates with the stimulator, and a processing system that controls the power system and the communication system. The central controller may instruct the stimulator to transmit one or more electrical pulses to the target location to affect an endocrine function (e.g., affect the glucose level of a patient).

公开(公告)号：US09700637B2

公开(公告)日：2017-07-11

申请号：US14783456

申请日：2014-04-28

申请人： Massachusetts Institute of Technology

发明人： Robert J. Radford ,  Stephen J. Lippard ,  Wen Chyan

IPC分类号： A61K49/00 ,  C07D405/14 ,  G01N33/58 ,  A61B5/00 ,  A61B5/145 ,  C07D311/16 ,  C07D493/10 ,  C07F9/54 ,  C07F3/06 ,  G01N33/84 ,  A61B5/1455

CPC分类号： A61K49/0039 ,  A61B5/0071 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4041 ,  A61B5/4064 ,  A61B5/425 ,  A61B5/4381 ,  C07D311/16 ,  C07D405/14 ,  C07D493/10 ,  C07F3/06 ,  C07F9/5442 ,  G01N33/582 ,  G01N33/84

摘要： Disclosed are compounds and methods useful in the detection of e.g., Zn2+, in vitro and in vivo. The compounds include amino acids and peptides functionalized with a moiety that binds, e.g., Zn2+. Importantly, the compounds do not exhibit substantial fluorescence in the absence of zinc.

公开(公告)号：US20170172450A1

公开(公告)日：2017-06-22

申请号：US15123867

申请日：2015-03-06

申请人： STC.UNM ,  Board of Regents, The University of Texas System ,  The Methodist Hospital

发明人： Eugene KOAY ,  Vittorio CRISTINI ,  Jason FLEMING ,  Priya BHOSALE ,  Christopher CRANE ,  Haifa SHEN ,  Mauro FERRARI

IPC分类号： A61B5/055 ,  A61B6/03 ,  A61B6/00 ,  A61B5/00

CPC分类号： A61B5/055 ,  A61B5/4233 ,  A61B5/425 ,  A61B5/4842 ,  A61B5/4848 ,  A61B6/032 ,  A61B6/12 ,  A61B6/481 ,  A61B6/5217 ,  A61B2576/00 ,  A61K49/0002 ,  G01R33/5601 ,  G06T7/0016 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/30096

摘要： Disclosed are method of detecting or characterizing a tumor by quantitatively measuring and comparing changes in mass transfer into the tumor and normal tissue over time using computed tomography or magnetic resonance imaging. The methods can be used to predict therapeutic response to treatment and to develop treatment plans.

公开(公告)号：US20170016883A1

公开(公告)日：2017-01-19

申请号：US15278933

申请日：2016-09-28

申请人： BioCrine AB

发明人： Per-Olof Berggren

IPC分类号： G01N33/50 ,  A61B3/13 ,  A61B5/00 ,  A61K49/00

CPC分类号： G01N33/5026 ,  A61B3/10 ,  A61B3/13 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/4227 ,  A61B5/425 ,  A61B5/4842 ,  A61B5/4848 ,  A61K49/0004 ,  A61K49/0008 ,  A61K49/0041 ,  A61K49/0054 ,  A61K49/0097 ,  G01N33/5088 ,  G01N2800/042

摘要： The present invention provides method for monitoring physiological status of an organ in a subject by monitoring morphological changes over time in transplanted tissue on an eye of the subject.

摘要翻译： 本发明提供了通过监测受试者的眼睛上的移植组织中随时间的形态学变化来监测受试者的器官的生理状态的方法。