Abstract:
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein R1, R2 and R3 are defined herein.
Abstract:
An Integrated Circuit Design tool incorporating a Stochastic Analysis Process (“SAP”) is described. The SAP can be applied on many levels of circuit components including transistor devices, logic gate devices, and System-on-Chip or chip designs. The SAP replaces a large number of traditional Monte Carlo simulations with operations using a small number of sampling points or corners. The SAP is a hierarchical approach using a model fitting process to generate a model that can be used with any number of performance memos to generate performance variation predictions along with corresponding statistical information (e.g., mean, three-sigma probability, etc.). The SAP provides an efficient way of modeling the circuit or system variation due to global parameters such as device dimensions, interconnect wiring variations, economic variations, and manufacturing variations.
Abstract:
An automobile exhaust system includes a catalytic converter and a modified NOx trap wit improved sulfur tolerance. Sulfur oxide has a deleterious effect on the performance of nitrogen oxide traps. In the modified NOx trap, a sulfur oxide trap is integrated with a nitrogen oxide trap by coating the catalyst contained within a nitrogen oxide trap with a mixed oxide layer of calcium oxide and magnesium oxide. The NOx trap is regenerated by heating at elevated temperature for a short time period.
Abstract:
A power saving apparatus (20) is interposed between a power supply unit (10) and an electronic device (30). The power saving apparatus includes a switching component (210), a controlling circuit (230) controllable by the electronic device, and a switching circuit (220) controllable by the controlling circuit and the switching component. The controlling circuit receives an “idle” signal from the electronic device and controls the switching circuit to cut off the power supply to the electronic device according to the “idle” signal. The switching component produces an “awakening” signal to control the switching circuit to resume the power supply to the electronic device. A related power saving method is also introduced.
Abstract:
A catalyst system for use with an internal combustion engine to provide emissions reductions under lean and stoichiometric operating conditions. The catalyst system comprises a first catalyst comprised of a newly developed Perovskite-based formulation having an ABO3 crystal structure designed to bring the precious metal and NOx trapping elements close together. The first catalyst acts primarily to maximize the reduction of emissions under lean operating conditions. The catalyst system also comprises a second catalyst comprised of precious metals which acts primarily to maximize the reduction of emissions under stoichiometric conditions.
Abstract:
Heat sink structures employing carbon nanotube or nanowire arrays to reduce the thermal interface resistance between an integrated circuit chip and the heat sink are disclosed. Carbon nanotube arrays are combined with a thermally conductive metal filler disposed between the nanotubes. This structure produces a thermal interface with high axial and lateral thermal conductivities.
Abstract:
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme (e.g., cathespin K). The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
Abstract:
Method and system for fabricating an electrical interconnect capable of supporting very high current densities (106–1010 Amps/cm2), using an array of one or more carbon nanotubes (CNTs). The CNT array is grown in a selected spaced apart pattern, preferably with multi-wall CNTs, and a selected insulating material, such as SiOw or SiuNv, is deposited using CVD to encapsulate each CNT in the array. An exposed surface of the insulating material is planarized to provide one or more exposed electrical contacts for one or more CNTs.
Abstract translation:用于制造能够支持非常高的电流密度(10 -6至10 10 Amps / cm 2)的电互连的方法和系统,使用 一个或多个碳纳米管(CNT)的阵列。 CNT阵列以选择的间隔开的图案生长,优选地使用多壁CNT,并且选择的绝缘材料,例如SiO 2或Si N 使用CVD沉积每个CNT以阵列中的每一个CNT。 绝缘材料的暴露表面被平坦化以为一个或多个CNT提供一个或多个暴露的电接触。
Abstract:
A wireless telephony communications system includes at least one macro cell for communicating both voice and data with a mobile communications device across a first wireless link and at least one micro cell for communicating data with the mobile communications device across a second wireless communication link. Each micro cell communicates signaling information through the macro cell via a wireless link to a control element that manages the micro cells. Using a wireless link to communicate signaling between each micro cell and the control element in the UMTS system eliminates the need for a wired back haul link, thereby reducing access costs.
Abstract:
The present invention is a method of applying Lotus Effect materials as a (superhydrophobicity) protective coating for external electrical insulation system applications, as well as the method of fabricating/preparing Lotus Effect coatings. Selected inorganic or polymeric materials are applied on the insulating material surface, and stable superhydrophobic coatings can be fabricated. Various UV stabilizers and UV absorbers can be incorporated into the coating system to enhance the coating's UV stability.