公开(公告)号：US08334027B2

公开(公告)日：2012-12-18

申请号：US11833679

申请日：2007-08-03

Applicant: Wook-Seong Lee ,  Young-Joon Baik ,  Jeung-Hyun Jeong ,  Ki-Woong Chae

Inventor： Wook-Seong Lee ,  Young-Joon Baik ,  Jeung-Hyun Jeong ,  Ki-Woong Chae

IPC: H05H1/24

CPC classification number: C23C16/503 ,  C23C16/272 ,  Y10T428/268

Abstract: In the method for depositing a material in the absence of a positive column, a discharge is generated between a cathode and an anode disposed to face each other in a reaction chamber by applying a DC voltage therebetween, and introducing reaction gas into the reaction chamber, thereby depositing a material on a substrate mounted on the anode and serving as a part of the anode, wherein the deposition of the material on the substrate is performed under a state that a cathode glow and an anode glow exist in a form of thin layers coating respectively the surfaces of the cathode and the substrate, while a positive column does not exist or is so small as to be negligible.

Abstract translation: 在不存在正极柱时沉积材料的方法中，通过在反应室中施加直流电压，在反应室内彼此面对的阴极和阳极之间产生放电，并将反应气体引入反应室， 从而将材料沉积在安装在阳极上并用作阳极的一部分的衬底上，其中材料在衬底上的沉积在阴极辉光和阳极辉光以薄层涂层形式存在的状态下进行 分别是阴极和衬底的表面，而正柱不存在或太小以致可以忽略。

公开(公告)号：US08318268B2

公开(公告)日：2012-11-27

申请号：US13316634

申请日：2011-12-12

Applicant: Jae-Kap Lee ,  So-Hyung Lee ,  Seung-Cheol Lee ,  Jae-Pyoung Ahn ,  Jeon-Kook Lee ,  Wook-Seong Lee

Inventor： Jae-Kap Lee ,  So-Hyung Lee ,  Seung-Cheol Lee ,  Jae-Pyoung Ahn ,  Jeon-Kook Lee ,  Wook-Seong Lee

IPC: C23C16/00

CPC classification number: B01J3/006 ,  B01J19/088 ,  B01J2219/0809 ,  B01J2219/0879 ,  B01J2219/0894 ,  C01B32/20 ,  C01B32/25 ,  C01B32/28 ,  C30B29/04 ,  C30B33/02 ,  Y10T428/30

Abstract: There is provided a fabrication method for an AA stacked graphene-diamond hybrid material by converting, through a high temperature treatment on diamond, a diamond surface into graphene. According to the present invention, if various types of diamond are maintained at a certain temperature having a stable graphene phase (approximately greater than 1200° C.) in a hydrogen gas atmosphere, two diamond {111} lattice planes are converted into one graphene plate (2:1 conversion), whereby the diamond surface is converted into graphene in a certain thickness, thus to fabricate the AA stacked graphene-diamond hybrid material.

Abstract translation: 通过将金刚石上的高温处理，金刚石表面转化成石墨烯，提供了一种用于AA堆叠的石墨烯 - 金刚石混合材料的制造方法。 根据本发明，如果各种类型的金刚石在氢气气氛中保持在稳定的石墨烯相（大约大于1200℃）的一定温度下，则将两个菱形{111}晶格面转换为一个石墨烯板 （2:1转化），由此将金刚石表面转化成一定厚度的石墨烯，从而制造AA堆叠的石墨烯 - 金刚石混合材料。

公开(公告)号：US20120295107A1

公开(公告)日：2012-11-22

申请号：US13475110

申请日：2012-05-18

Applicant: Jae Kap LEE

Inventor： Jae Kap LEE

IPC: C01B31/04 ,  B32B9/00 ,  B82Y40/00 ,  B82Y30/00

CPC classification number: B32B9/00 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/19 ,  C01B32/194 ,  C01B32/20 ,  Y10T428/2918

Abstract: The present invention relates to a method of fabricating a carbon material and, more particularly, to a method for fabricating graphite having a nano-ribbon shape (hereinafter, referred to as a ‘graphene-controlled nano-graphite’) through a heat treatment of graphene nano-powders, and a graphene-controlled nano-graphite fabricated through the method. The method for fabricating graphene-controlled nano-graphite includes a preparation step of preparing graphene powders and a fabrication step of fabricating graphene-controlled nano-graphite through heat treatment of the graphene powders. The graphene powder may be fabricated by disintegrating crystalline graphite.

Abstract translation: 本发明涉及一种制造碳材料的方法，更具体地说，涉及通过石墨烯纳米管的热处理制造具有纳米带状的石墨的方法（以下称为石墨烯控制的纳米石墨） 粉末和通过该方法制造的石墨烯控制的纳米石墨。 制造石墨烯控制的纳米石墨的方法包括制备石墨烯粉末的制备步骤和通过石墨烯粉末的热处理来制造石墨烯控制的纳米石墨的制造步骤。 石墨烯粉末可以通过分解结晶石墨来制造。

公开(公告)号：US08313744B2

公开(公告)日：2012-11-20

申请号：US12851137

申请日：2010-08-05

Applicant: Eunji Cheong ,  Hee-Sup Shin ,  Yihong Zheng ,  Kyoobin Lee ,  Jungryun Lee ,  Seongwook Kim ,  Maryam Sanati ,  Sukyung Lee ,  Yeon-Soo Kim ,  Sukchan Lee

Inventor： Eunji Cheong ,  Hee-Sup Shin ,  Yihong Zheng ,  Kyoobin Lee ,  Jungryun Lee ,  Seongwook Kim ,  Maryam Sanati ,  Sukyung Lee ,  Yeon-Soo Kim ,  Sukchan Lee

IPC: A61K38/48 ,  A61K31/21 ,  A61K31/12 ,  A61K31/045 ,  A61K31/015 ,  A01N37/00 ,  A01N35/00 ,  A01N31/00 ,  A01N27/00

CPC classification number: A61K31/215 ,  A61K31/23 ,  A61K31/357 ,  A61K31/365 ,  A61K31/37 ,  A61K31/404 ,  A61K31/41 ,  A61K31/575 ,  A61K38/4833

Abstract: The present invention relates to a composition comprising PKC agonist as an active ingredient. More precisely, the present inventors confirmed that absence seizure specific SWD was reduced by administrating PKC agonist into an animal model. Therefore, the composition of the present invention comprising PKC agonist as an active ingredient can be effectively used for the prevention and treatment of absence seizure and for the production of health improving functional food.

Abstract translation: 本发明涉及包含PKC激动剂作为活性成分的组合物。 更准确地说，本发明人证实，通过将PKC激动剂施用到动物模型中，不存在发作特异性SWD被降低。 因此，包含PKC激动剂作为活性成分的本发明的组合物可以有效地用于预防和治疗不发作和用于生产健康改善功能性食物。

公开(公告)号：US20120276651A1

公开(公告)日：2012-11-01

申请号：US13362183

申请日：2012-01-31

Applicant: Sehoon KIM ,  Ick Chan Kwon ,  Jai Kyeong Kim ,  Chang-Keun Lim ,  Jeongyun Heo

Inventor： Sehoon KIM ,  Ick Chan Kwon ,  Jai Kyeong Kim ,  Chang-Keun Lim ,  Jeongyun Heo

IPC: G01N21/64 ,  C07C65/05 ,  C07C255/53 ,  C07C309/73 ,  C07C69/732 ,  C07C49/248 ,  C07C49/573 ,  C07D403/10 ,  C07C69/88 ,  C07C255/57

CPC classification number: C07D239/60 ,  C07C39/373 ,  C07C47/565 ,  C07C49/248 ,  C07C49/747 ,  C07C69/732 ,  C07C69/94 ,  C07C255/36 ,  C07C255/40 ,  C07C255/41 ,  C07C309/73 ,  C07C317/46 ,  C07C2602/08 ,  C07D403/10 ,  Y10T436/206664

Abstract: The present disclosure relates to a sulfonated benzene compound emitting fluorescence by reaction with hydrogen peroxide, aqueous-dispersed fluorescent nanoprobes applicable for real-time detection of hydrogen peroxide, and a fluorescent nanoprobe fabrication method. The fluorescent nanoprobe contains the following sulfonated benzene compound and water.

Abstract translation: 本公开内容涉及通过与过氧化氢反应发射荧光的磺化苯化合物，适用于过氧化氢的实时检测的水分散荧光纳米探针和荧光纳米探针制造方法。 荧光纳米探针含有以下磺化苯化合物和水。

公开(公告)号：US08298495B2

公开(公告)日：2012-10-30

申请号：US13334113

申请日：2011-12-22

Applicant: Kyeong Seok Lee ,  Won Mok Kim ,  Taek Sung Lee

Inventor： Kyeong Seok Lee ,  Won Mok Kim ,  Taek Sung Lee

IPC: G01N33/52 ,  G01N21/00

CPC classification number: G01N21/554 ,  B82Y15/00 ,  B82Y20/00 ,  G01N21/648 ,  G01N21/658

Abstract: The present invention relates to a high sensitivity localized surface plasmon resonance sensor and to a sensor system using same, the sensor comprising: a first metal layer including a first metal; a second metal layer arranged parallel to the first metal layer and including a second metal; and a conductive cross-linking layer disposed between the first metal layer and the second metal layer, and made of a third metal with a corrosion response that is different than that of the first metal and of the second metal.

Abstract translation: 本发明涉及高灵敏度局部表面等离子体共振传感器和涉及使用它的传感器系统，该传感器包括：第一金属层，包括第一金属; 第二金属层，其平行于第一金属层布置并包括第二金属; 以及设置在第一金属层和第二金属层之间的导电交联层，并且由具有不同于第一金属和第二金属的腐蚀响应的第三金属制成。

公开(公告)号：US20120271048A1

公开(公告)日：2012-10-25

申请号：US13504355

申请日：2010-10-20

Applicant: Tae Bo Sim ,  Young Jin Ham ,  Kyung Ho Yoo ,  Chang Hyun Oh ,  Jung Mi Hah ,  Hwan Geun Choi ,  Hwan Kim ,  Eun Jin Jun

Inventor： Tae Bo Sim ,  Young Jin Ham ,  Kyung Ho Yoo ,  Chang Hyun Oh ,  Jung Mi Hah ,  Hwan Geun Choi ,  Hwan Kim ,  Eun Jin Jun

IPC: C07D403/04 ,  C07D487/04 ,  C07D413/14

CPC classification number: C07D403/04 ,  A61K31/404 ,  C07D403/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07D417/14 ,  C07D487/04

Abstract: Disclosed are a 1,6-substituted indole compound having a protein kinase inhibition activity, a pharmaceutically acceptable salt, and a pharmaceutical composition for prevention and treatment of cancers caused by abnormal cell growth comprising the compound as an effective ingredient.Since the novel indole compound exhibits superior inhibition activity against various protein kinases involved in growth factor signal transduction, it is useful as an agent for preventing or treating cancers caused by abnormal cell growth.

Abstract translation: 公开了具有蛋白激酶抑制活性的1,6-取代的吲哚化合物，药学上可接受的盐，以及用于预防和治疗由包含该化合物作为有效成分的异常细胞生长引起的癌症的药物组合物。 由于新型吲哚化合物对参与生长因子信号转导的各种蛋白激酶具有优异的抑制活性，因此可用作预防或治疗由异常细胞生长引起的癌症的药剂。

公开(公告)号：US20120270234A1

公开(公告)日：2012-10-25

申请号：US12987863

申请日：2011-01-10

Applicant: Beom-Seok YANG ,  Sung-Dae Park

Inventor： Beom-Seok YANG ,  Sung-Dae Park

IPC: C12N9/12 ,  C12Q1/48 ,  G01N21/76 ,  C12N15/866

CPC classification number: C07K14/705 ,  C07K2319/00 ,  C07K2319/21 ,  C07K2319/23 ,  C07K2319/35 ,  C12N9/1205

Abstract: The present invention relates to a protein containing a modified DDR (Discoidin Domain Receptor) 2 cytosolic tyrosine kinase domain having an increased autophosphorylation and tyrosine kinase activity; a method for preparing a large amount of a protein containing DDR2 cytosolic tyrosine kinase domain, having an increased autophosphorylation and tyrosine kinase activity by inducing phosphorylations of tyrosines by a co-expression with Src or Src related proteins in host cells, or by H2O2 processing of host cells, or a site directed mutation modifying at least one of tyrosines to other amino acid; and a use thereof as a target material in developing medical drugs for treating a disease caused by an excessively activated DDR2 autophosphorylation and tyrosine kinase activity.

Abstract translation: 本发明涉及含有增加的自磷酸化和酪氨酸激酶活性的修饰的DDR（盘带蛋白结构域受体）2胞质酪氨酸激酶结构域的蛋白质; 通过与宿主细胞中的Src或Src相关蛋白的共表达，或通过H 2 O 2处理，通过诱导酪氨酸的磷酸化，具有增加的自磷酸化和酪氨酸激酶活性的DDR2胞质酪氨酸激酶结构域的蛋白质的制备方法 宿主细胞或将至少一种酪氨酸修饰至其它氨基酸的位点定向突变; 以及其用作开发用于治疗由过度活化的DDR2自磷酸化和酪氨酸激酶活性引起的疾病的药物的目标材料。

公开(公告)号：US08293138B2

公开(公告)日：2012-10-23

申请号：US12004274

申请日：2007-12-19

Applicant: Hyoung-Juhn Kim ,  Jeung Woo Lee ,  Tae-Hoon Lim ,  Suk Woo Nam ,  Seong-Ahn Hong ,  In-Hwan Oh ,  Hyung Chul Ham ,  Sang-Yeop Lee

Inventor： Hyoung-Juhn Kim ,  Jeung Woo Lee ,  Tae-Hoon Lim ,  Suk Woo Nam ,  Seong-Ahn Hong ,  In-Hwan Oh ,  Hyung Chul Ham ,  Sang-Yeop Lee

IPC: H01B1/12 ,  C08G73/06

CPC classification number: C08J5/2256 ,  C08G73/18 ,  C08J2379/04 ,  H01M8/103 ,  H01M8/1048 ,  H01M8/1072 ,  H01M2300/0082 ,  Y02P70/56

Abstract: A partially sulfonated polybenzimidazole based polymer for fuel cell membrane is prepared by copolymerizing monomers of 3,3′-diaminobenzidine, isophthalic acid and 5-sulfoisophthalic acid to obtain a partially sulfonated polybenzimidazole, and doping the partially sulfonated polybenzimidazole with inorganic acid.

Abstract translation: 通过共聚3,3'-二氨基联苯胺，间苯二甲酸和5-磺基间苯二甲酸的单体制备用于燃料电池膜的部分磺化的聚苯并咪唑基聚合物，以获得部分磺化的聚苯并咪唑，并用无机酸掺杂部分磺化的聚苯并咪唑。

公开(公告)号：US20120232127A1

公开(公告)日：2012-09-13

申请号：US13418486

申请日：2012-03-13

Applicant: Justin Changjoon LEE ,  Dong-Ho Woo ,  Hyung-Ju Park ,  Hye-Kyung Park

Inventor： Justin Changjoon LEE ,  Dong-Ho Woo ,  Hyung-Ju Park ,  Hye-Kyung Park

IPC: A61K31/7088 ,  A61K31/26 ,  A61K31/196 ,  A61P25/00 ,  A61K31/44

CPC classification number: C12N15/1138 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53

Abstract: A novel use of anion channels, preferably Ca2+-activated anion channels (CAACs), in regulating release of neurotransmitters from neurons and/or astrocytes is provided. More specifically, CAAC activity regulators, agents for regulating neurotransmitter release comprising such CAAC activity regulators, and methods of screening agents for regulating neurotransmitter release using CAAC as a target.

Abstract translation: 提供阴离子通道，优选Ca2 +活化阴离子通道（CAAC）在调节神经元和/或星形胶质细胞释放神经递质中的新用途。 更具体地，CAAC活性调节剂，用于调节包含这种CAAC活性调节剂的神经递质释放剂，以及使用CAAC作为靶标调节神经递质释放调节剂的方法。