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85 条记录 (耗时 0.045 秒)

    Method and apparatus for termination of tachyarrhythmias
    51.
    发明授权
    Method and apparatus for termination of tachyarrhythmias 失效
    用于终止快速性心律失常的方法和装置

    公开(公告)号：US5849031A

    公开(公告)日：1998-12-15

    申请号：US991838

    申请日：1997-12-16

    申请人： Gonzalo Martinez ,  David Lipson ,  Timothy G. Laske

    发明人： Gonzalo Martinez ,  David Lipson ,  Timothy G. Laske

    IPC分类号： A61N1/05 ,  A61N1/39

    CPC分类号： A61N1/3918 ,  A61N1/0563 ,  Y10S977/952

    摘要： An implantable medical lead for use with an implantable cardioverter defibrillator, a method of manufacture and a system employing the lead and cardioverter/defibrillator in combination. The lead is provided with an elongated insulative lead body carrying a cardioversion/defibrillation electrode, which includes a first portion displaying essentially equal attenuation of positive and negative voltage pulses and a second portion displaying differential attenuation of positive and negative voltage pulses. The cardioveter/defibrillator provides a biphasic pulse in which a higher amplitude phase of the pulse is differentially attenuated by the electrode. The electrode is fabricated in whole or in part of a valve metal such as tantalum, anodized and annealed to provide a thick, durable oxide coating.

    摘要翻译： 一种用于植入式心律转复除颤器的可植入医用引线，一种制造方法，以及组合使用引线和心律转复除颤器的系统。 引线设置有承载心电复律/除颤电极的细长绝缘引线体，其包括显示正负电压脉冲基本上相等的衰减的第一部分和显示正和负电压脉冲的差分衰减的第二部分。 心脏除颤器/除颤器提供双相脉冲，其中脉冲的较高振幅相位被电极差分衰减。 电极全部或部分地由诸如钽的阀金属制成，经过阳极氧化和退火，以提供厚实耐用的氧化物涂层。

    Conductor cable for biomedical lead
    52.
    发明授权
    Conductor cable for biomedical lead 失效
    用于生物医学铅的导线

    公开(公告)号：US5760341A

    公开(公告)日：1998-06-02

    申请号：US711829

    申请日：1996-09-10

    申请人： Timothy G. Laske ,  David W. Mayer

    发明人： Timothy G. Laske ,  David W. Mayer

    IPC分类号： H01B7/00 ,  H01B7/04 ,  H01B5/08

    CPC分类号： H01B7/0009 ,  H01B7/048

    摘要： A biomedical lead conductor cable formed of a core wire strand and a plurality of perimeter wire strands wrapped in a helical pattern around the core wire strand, wherein the core wire strand is formed of M wires and the perimeter wire strands are formed of N wires. The core wire strand is formed of a first core wire and M-1 first peripheral wires helically wrapped about the first core wire in a non-overlapping manner, the first core wire having a mechanical strength exceeding the mechanical strength of each first peripheral wire and an electrical conductivity lower than the electrical conductivity of each first peripheral wire. Each perimeter wire strand is formed of a second core wire and N-1 second peripheral wires helically wrapped about the second core wire in a non-overlapping manner, the second core wire conductor having a mechanical strength exceeding the mechanical strength of each second peripheral wire and an electrical conductivity lower than the electrical conductivity of each second peripheral wire. In a preferred embodiment M=N, and the first core wire is formed of a solid metal or metal alloy, whereas first peripheral wires are formed of a composite conductor wire having a core of high conductivity material surrounded by a cladding of lower conductivity material. The second core wire is also preferably formed of a composite conductor wire. The diameters of the first and second core wires exceed the diameters of the first and second peripheral wires, respectively to provide a spacing between adjacent peripheral wires wound helically about the core wires. Moreover, preferably, the diameter of the core wire strand exceeds the diameter of the perimeter wire strands to provide a spacing between the adjacent perimeter wire strands wound about the core wire strand.

    摘要翻译： 一种生物医学引线导体电缆，其由芯线股线和围绕芯线股卷绕成螺旋形图案的多个周边线股形成，其中，芯线股线由M根线形成，并且周边线股由N根线形成。 芯线由第一芯线和以不重叠的方式围绕第一芯线螺旋缠绕的M-1个第一外围线形成，第一芯线的机械强度超过每个第一外围线的机械强度， 导电率低于每个第一外围导线的导电性。 每个周边线束由第二芯线和以非重叠方式围绕第二芯线螺旋缠绕的N-1个第二外围线形成，第二芯线导体的机械强度超过每个第二周边线的机械强度 并且电导率低于每个第二外围导线的电导率。 在优选实施例中，M = N，第一芯线由固体金属或金属合金形成，而第一外围线由具有由较低导电性材料的包层围绕的具有高导电性材料的芯的复合导线形成。 第二芯线也优选由复合导线形成。 第一和第二芯线的直径分别超过第一外围线和第二外围线的直径，以在围绕芯线螺旋形缠绕的相邻外围线之间提供间隔。 此外，优选地，芯线股线的直径超过周边线股的直径，以在围绕芯线股线缠绕的相邻周边线股之间提供间隔。

    Delivery Systems and Methods of Implantation for Prosthetic Heart Valves
    57.
    发明申请
    Delivery Systems and Methods of Implantation for Prosthetic Heart Valves 有权
    假体心脏瓣膜植入系统和方法

    公开(公告)号：US20090198316A1

    公开(公告)日：2009-08-06

    申请号：US12357980

    申请日：2009-01-22

    申请人： Timothy G. Laske ,  Timothy R. Ryan ,  Carolyn C. Majkrzak ,  Eliot Bloom ,  Charles Tabor

    发明人： Timothy G. Laske ,  Timothy R. Ryan ,  Carolyn C. Majkrzak ,  Eliot Bloom ,  Charles Tabor

    IPC分类号： A61F2/06 ,  A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2403 ,  A61F2/2412 ,  A61F2/243 ,  A61F2/2436 ,  A61F2/82 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2250/0098

    摘要： A method of deploying an implantable stented device in an anatomical location of a patient, including the steps of providing a delivery system with first and second stent engagement structures at its distal end, attaching a first structural element of the stented device to the first stent engagement structure and attaching a second structural element of the stented device to the second stent engagement structure, advancing the stented device to an implantation site, and sequentially disengaging the first structural element of the stented device from the first stent engagement structure of the delivery system and then disengaging the second structural element of the stented device from the second stent engagement structure.

    摘要翻译： 一种将可植入支架装置部署在患者的解剖位置的方法，包括以下步骤：在其远端处提供具有第一和第二支架接合结构的输送系统，将支架装置的第一结构元件附接到第一支架接合 结构并将支架装置的第二结构元件附接到第二支架接合结构，将支架装置推进到植入部位，并且将支架装置的第一结构元件与递送系统的第一支架接合结构顺序地分离，然后 将支架装置的第二结构元件与第二支架接合结构分离。

    ELECTRONIC AND BIOLOGICAL PACEMAKER SYSTEMS
    58.
    发明申请
    ELECTRONIC AND BIOLOGICAL PACEMAKER SYSTEMS 有权
    电子与生物学系统

    公开(公告)号：US20080103537A1

    公开(公告)日：2008-05-01

    申请号：US11554770

    申请日：2006-10-31

    申请人： Daniel C. Sigg ,  Timothy G. Laske ,  Vinod Sharma ,  Orhan Soykan

    发明人： Daniel C. Sigg ,  Timothy G. Laske ,  Vinod Sharma ,  Orhan Soykan

    IPC分类号： A61N1/00

    CPC分类号： A61N1/362 ,  A61N1/3627

    摘要： Heart pacing systems include at least one electronic or biological pacemaker as a primary pacemaker, and at least one electronic or biological pacemaker as a backup pacemaker. When implanted, the primary pacemaker(s) produce primary pacing stimuli that modulate cardiac function. The backup pacemaker(s) provide backup pacing stimuli when the electronic pacemaker is unable to modulate cardiac function at the predetermined pacing rate. The heart pacing systems are implemented by implantation in regions where they can provide pacing stimuli to cardiac tissue.

    摘要翻译： 心脏起搏系统包括至少一个电子或生物起搏器作为主要起搏器，以及至少一个电子或生物起搏器作为备用起搏器。 当植入时，主起搏器产生调节心脏功能的主要起搏刺激。 当电子起搏器不能以预定起搏速度调节心脏功能时，备用起搏器提供备用起搏刺激。 心脏起搏系统通过植入在可以为心脏组织提供起搏刺激的区域中实现。

    Means for increasing implantable medical device electrode surface area
    60.
    发明授权
    Means for increasing implantable medical device electrode surface area 有权
    增加植入式医疗器械电极表面积的手段

    公开(公告)号：US07191009B2

    公开(公告)日：2007-03-13

    申请号：US10914303

    申请日：2004-08-09

    申请人： Timothy G. Laske ,  Gonzalo Martinez ,  Lea A. Nygren

    发明人： Timothy G. Laske ,  Gonzalo Martinez ,  Lea A. Nygren

    IPC分类号： A61N1/00

    CPC分类号： A61N1/375 ,  A61N1/3756

    摘要： A surface area of an IMD electrode is increased by forming a conductive layer over an external portion of a sidewall of an IMD connector header and electrically coupling the conductive layer of the connector header to a conductive mounting surface of a hermetically sealed IMD housing; wherein the conductive mounting surface is an extension of an external conductive surface of the IMD, which external conductive surface forms the IMD electrode that is increased in surface area by the conductive layer formed over the connector header.

    摘要翻译： 通过在IMD连接器集管的侧壁的外部部分上形成导电层并将连接器集管的导电层电耦合到密封的IMD壳体的导电安装表面来增加IMD电极的表面积; 其中所述导电安装表面是所述IMD的外部导电表面的延伸部，所述外部导电表面形成所述IMD电极，所述IMD电极通过形成在所述连接器插头上的导电层而在表面积上增加。