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51.发明授权公开(公告)号：US07371549B2
公开(公告)日：2008-05-13
申请号：US11362915
申请日：2006-02-28
摘要： The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for producing optically active monatin, and aldolase used for these methods. As such, the present invention enables the synthesis of 4-(Indole-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid with high optical purity, which is useful as an intermediate in the synthesis of optically active monatin, from indole pyruvic acid and pyruvic acid (or oxaloacetic acid).
摘要翻译： 本发明涉及一种用于制备光学活性的IHOG的方法，其可以用于制备莫纳甜。 本发明还涉及用于制备光学活性莫纳甜的方法和用于这些方法的醛缩酶。 因此，本发明能够合成具有高光学纯度的4-（吲哚-3-基甲基）-4-羟基-2-氧代戊二酸，其可用作在光学活性莫纳甜的合成中的吲哚丙酮酸的中间体 酸和丙酮酸（或草酰乙酸）。
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公开(公告)号：US07351571B2
公开(公告)日：2008-04-01
申请号：US11198242
申请日：2005-08-08
CPC分类号： C12P13/04 , C12P41/006 , C12R1/01
摘要： The present invention relates to a Variovorax sp. which produces an acylase having an asymmetric hydrolysis activity on an N-acetyl β-amino acid to selectively produce an R-β-amino acid, and a Burkholderia sp. which produces both an acylase having an asymmetric hydrolysis activity on an N-acetyl β-amino acid to selectively produce an S-β-amino acid and an acylase having an asymmetric hydrolysis activity of an N-acetyl β-amino acid to selectively produce an R-β-amino acid, and a process for the selective production of an S-, or R-β-amino acid using the above strains.
摘要翻译： 本发明涉及一种Variovorax sp。 其产生对N-乙酰基β-氨基酸具有不对称水解活性以选择性地产生R-β-氨基酸的酰基转移酶和伯克霍尔德氏菌属（Burkholderia sp。 其产生对N-乙酰基β-氨基酸具有不对称水解活性的酰基转移酶以选择性地产生具有N-乙酰基β-氨基酸的不对称水解活性的S-β-氨基酸和酰基转移酶，以选择性地产生 R-β-氨基酸，以及使用上述菌株选择性生产S-或R-β-氨基酸的方法。
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公开(公告)号：US20070292916A1
公开(公告)日：2007-12-20
申请号：US11765926
申请日：2007-06-20
申请人： Isao ABE , Rie Takeshita , Seiichi Hara , Sonoko Suzuki , Kenzo Yokozeki , Masakazu Sugiyama , Shunichi Suzuki , Kunihiko Watanabe , Nobuhisa Shimba , Takefumi Nakamura , Uno Tagami , Yuya Kodama , Hiromi Onoye , Reiko Yuuji , Eiichiro Suzuki , Tatsuki Kashiwagi , Ningchun Xu , Yuko Kai
发明人： Isao ABE , Rie Takeshita , Seiichi Hara , Sonoko Suzuki , Kenzo Yokozeki , Masakazu Sugiyama , Shunichi Suzuki , Kunihiko Watanabe , Nobuhisa Shimba , Takefumi Nakamura , Uno Tagami , Yuya Kodama , Hiromi Onoye , Reiko Yuuji , Eiichiro Suzuki , Tatsuki Kashiwagi , Ningchun Xu , Yuko Kai
CPC分类号： C07K14/00 , C07K14/195 , C12N9/93
摘要： The present invention aims at providing an excellent peptide-synthesizing protein and a method for efficiently producing a peptide. The peptide is synthesized by reacting an amine component and a carboxy component in the presence of at least one of proteins shown in the following (I) and (II). (I) The mutant protein having an amino acid sequence comprising one or more mutations from any of the mutations 1 to 68, and the mutations 239 to 290 and 324 to 377 in an amino acid sequence of SEQ ID NO:2. (II) The mutant protein having an amino acid sequence comprising one or more mutations from any of the mutations L1 to L335 and M1 to M642 in an amino acid sequence of SEQ ID NO:208
摘要翻译： 本发明的目的在于提供优异的肽合成蛋白质和有效生产肽的方法。 在下列（I）和（II）所示的至少一种蛋白质存在下，使胺组分和羧基组分反应合成肽。 （I）具有包含SEQ ID NO：2的氨基酸序列中的任何突变1至68和突变239至290和324至377的一个或多个突变的氨基酸序列的突变蛋白。 （II）具有包含SEQ ID NO：208的氨基酸序列中的任何突变L1至L335和M1至M642的一个或多个突变的氨基酸序列的突变蛋白
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54.发明授权公开(公告)号：US07241599B2
公开(公告)日：2007-07-10
申请号：US11146093
申请日：2005-06-07
摘要： The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for producing optically active monatin, and aldolase used for these methods. As such, the present invention enables the synthesis of 4-(Indole-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid with high optical purity, which is useful as an intermediate in the synthesis of optically active monatin, from indole pyruvic acid and pyruvic acid (or oxaloacetic acid).
摘要翻译： 本发明涉及一种用于制备光学活性的IHOG的方法，其可以用于制备莫纳甜。 本发明还涉及用于制备光学活性莫纳甜的方法和用于这些方法的醛缩酶。 因此，本发明能够合成具有高光学纯度的4-（吲哚-3-基甲基）-4-羟基-2-氧代戊二酸，其可用作在光学活性莫纳甜的合成中的吲哚丙酮酸的中间体 酸和丙酮酸（或草酰乙酸）。
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公开(公告)号：US20050214912A1
公开(公告)日：2005-09-29
申请号：US11091892
申请日：2005-03-29
申请人： Hiroyuki Nozaki , Kunihiko Watanabe
发明人： Hiroyuki Nozaki , Kunihiko Watanabe
CPC分类号： C12P13/225
摘要： A method for producing an optically active amino acid comprising contacting a 5-substituted hydantoin with a group of enzymes including both a hydantoinase and a carbamoylase, wherein the method is carried out in an aqueous solution with a dissolved oxygen concentration of 1.5 ppm or less. Optically active amino acids such as D-tyrosine may be produced with high efficiency.
摘要翻译： 一种光学活性氨基酸的制造方法，其特征在于，将5-取代的乙内酰脲与包括乙内酰脲酶和氨甲酰基酶的酶组合，其中所述方法在溶解氧浓度为1.5ppm以下的水溶液中进行。 可以高效率地生产D-酪氨酸等光活性氨基酸。
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公开(公告)号：US20050195338A1
公开(公告)日：2005-09-08
申请号：US11066237
申请日：2005-02-25
IPC分类号： G02F1/1345 , G02F1/1333 , G02F1/1368 , G09F9/30
CPC分类号： H01L27/124 , G02F1/13452 , G02F1/136204 , G02F1/136259 , G02F2001/136272 , H01L27/0296 , H01L2224/05553
摘要： An active matrix type display device includes inter-pad short-circuiting lines which are connected with signal lines, terminal portions which transmit signals from an IC chip to the signal lines, and a plurality of short-circuiting lines which are arranged outside the terminal portions and inside an end surface of a substrate and are connected with a plurality of inter-pad short-circuiting lines, wherein cut regions of the inter-pad short-circuiting lines are arranged outside the terminal portions and inside the short-circuiting lines. Since repair lines and signal-line lead line do not cross each other, it is possible to perform the highly reliable repair in respective manufacturing steps.
摘要翻译： 有源矩阵型显示装置包括与信号线连接的衬垫间短路线，从IC芯片向信号线发送信号的端子部以及设置在端子部外侧的多条短路线 并且在基板的端面内部并且与多个垫间短路线连接，其中，垫间短路线的切割区域布置在端子部分的外部和短路线内部。 由于维修线和信号线引线彼此不相交，因此可以在各个制造步骤中执行高度可靠的修理。
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公开(公告)号：US6140105A
公开(公告)日：2000-10-31
申请号：US359812
申请日：1999-07-23
申请人： Kunihiko Watanabe , Hiroshi Takemura , Mari Tabuchi , Naoki Tahara , Hiroshi Toyosaki , Yasushi Morinaga , Takayasu Tsuchida , Hisato Yano , Fumihiro Yoshinaga
发明人： Kunihiko Watanabe , Hiroshi Takemura , Mari Tabuchi , Naoki Tahara , Hiroshi Toyosaki , Yasushi Morinaga , Takayasu Tsuchida , Hisato Yano , Fumihiro Yoshinaga
CPC分类号： C12R1/02 , C12P19/04 , C12R1/01 , Y10S435/823
摘要： Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6.times.10.sup.4 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.
摘要翻译： 新型的纤维素生成菌，包括能够生产聚苯乙烯换算重量平均聚合度为1.6×10 4以上的细菌纤维素的纤维素生成菌，能够生产含少量低分子量的细菌纤维素的细菌纤维素 聚合，一种生产宾汉多糖作为副产物，一种生产少量水溶性多糖; 一种生产细菌纤维素的方法，包括培养这些纤维素生产菌; 和由此获得的细菌纤维素。
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公开(公告)号：US5917307A
公开(公告)日：1999-06-29
申请号：US911355
申请日：1997-08-07
申请人： Kunihiko Watanabe , Heiji Kuki , Shuji Arisaka , Toshiro Shimada
发明人： Kunihiko Watanabe , Heiji Kuki , Shuji Arisaka , Toshiro Shimada
CPC分类号： H01F38/14
摘要： In a magnetic coupling device for charging an electric vehicle which is used for charging a power storage device of the electric vehicle by means of a charging power source, a primary coil unit is inserted into a receiving unit which is on an electric vehicle and in which a secondary coil unit is disposed. In the device, junction faces of primary and secondary cores are formed in the insertion direction of the primary coil unit, and primary and secondary coils are disposed at positions where, when the primary coil unit 30 is inserted, the primary and secondary coils do not interfere with each other. Wiping members which wipe the junction faces are disposed. The insertion direction of the primary coil unit is in parallel with the longitudinal direction of the unit.
摘要翻译： 在用于通过充电电源对用于对电动车辆的蓄电装置充电的电动车辆的磁耦合装置中，将初级线圈单元插入到电动车辆上的接收单元中，其中 设置次级线圈单元。 在初级线圈单元的插入方向上形成初级和次级型芯的接合面，一级线圈和次级线圈设置在初级线圈单元30插入时，初级线圈单元和次级线圈不会 互相干扰 设置擦拭接合面的擦拭构件。 初级线圈单元的插入方向与单元的纵向方向平行。
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公开(公告)号：US5909099A
公开(公告)日：1999-06-01
申请号：US907000
申请日：1997-08-06
申请人： Kunihiko Watanabe , Heiji Kuki , Shuji Arisaka , Toshiro Shimada
发明人： Kunihiko Watanabe , Heiji Kuki , Shuji Arisaka , Toshiro Shimada
IPC分类号： A61K31/726 , A61K31/728 , H01F38/14 , H02J7/02 , H01M10/46
CPC分类号： H01F38/14 , A61K31/726 , A61K31/728 , B60L11/1818 , B60L11/182 , B60L11/1825 , H02J7/025 , B60L2210/30 , B60L2230/12 , B60L2230/14 , B60L2240/36 , Y02T10/7005 , Y02T10/7088 , Y02T10/7241 , Y02T90/121 , Y02T90/122 , Y02T90/127 , Y02T90/128 , Y02T90/14 , Y02T90/16
摘要： A charging system for use with an electric vehicle in that a primary coil 32 is structured in such a manner that a conductive pipe 34 is wound around a primary core 33. Cooling water is allowed to circulate through the conductive pipe 34, while the cooling water is cooled by a radiator device provided on the charging unit side. To the two ends of the conductive pipe 34, there are connected the core wires of a charging power cable 40 through energizing terminals 37, so that the primary coil 32 can be excited.
摘要翻译： 一种用于电动车辆的充电系统，其中初级线圈32被构造成使得导电管34缠绕在主芯33上。冷却水允许通过导电管34循环，同时冷却水 被设置在充电单元侧的散热器装置冷却。 在导电管34的两端，通过激励端子37连接充电电力电缆40的芯线，使得初级线圈32能够被激励。
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公开(公告)号：US5907231A
公开(公告)日：1999-05-25
申请号：US882149
申请日：1997-06-25
申请人： Kunihiko Watanabe , Heiji Kuki , Shuji Arisaka , Toshiro Shimada
发明人： Kunihiko Watanabe , Heiji Kuki , Shuji Arisaka , Toshiro Shimada
CPC分类号： H01F38/14
摘要： A magnetic coupling device for charging an electric vehicle includes: a primary unit having a primary core and a primary coil wound on the primary core; and a secondary unit having a secondary core and a secondary coil wound on the secondary core, the secondary unit disposed on the electric vehicle and coupled with the primary unit, so that the primary and secondary cores constitute a closed loop-like magnetic circuit; each of the primary and secondary cores having a junction face which contacts with each other under the coupling, wherein the junction faces of the primary and secondary cores have a mutually opposing relationship in which the junction faces intersect with an attaching direction of the primary unit.
摘要翻译： 一种用于对电动车辆进行充电的磁耦合装置包括：主单元，其具有缠绕在主芯上的初级芯和初级线圈; 以及次级单元，其具有卷绕在次级芯上的次级线圈和次级线圈，所述次级单元设置在所述电动车辆上并与所述主单元耦合，使得所述主芯和次铁芯构成闭环状磁路; 所述主芯和次芯中的每一个具有在耦合下彼此接触的接合面，其中所述主芯和次芯的接合面具有相互相对的关系，其中所述接合面与所述主单元的附接方向相交。
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