公开(公告)号：US20150150843A1

公开(公告)日：2015-06-04

申请号：US14402512

申请日：2013-05-16

申请人： Randall T. Peterson ,  Yan Liu

发明人： Randall T. Peterson ,  Yan Liu

IPC分类号： A61K31/352 ,  A61K49/00

CPC分类号： A61K31/352 ,  A61K31/17 ,  A61K31/37 ,  A61K31/496 ,  A61K31/704 ,  A61K49/0008 ,  A61K2300/00

摘要： The invention provides a method of reducing anthracycline-induced cardiotoxicity by administering a toxicity-reducing compound, such as a compound of Formulas (I), (II) or (III) or a combination thereof, and/or diphenyl urea (DPU), dexrazoxane (DEX), to a patient receiving an anthracycline. The invention also provides a method of identifying toxicity-reducing compounds.

摘要翻译： 本发明提供了通过施用毒性降低化合物，例如式（I），（II）或（III）的化合物或其组合和/或二苯基脲（DPU），降低蒽环类诱导的心脏毒性的方法， 右美沙芬（DEX）给予接受蒽环类抗生素的患者。 本发明还提供鉴定毒性降低化合物的方法。

公开(公告)号：US08895302B2

公开(公告)日：2014-11-25

申请号：US13207202

申请日：2011-08-10

申请人： Su-Chun Zhang ,  Yan Liu ,  Lixiang Ma

发明人： Su-Chun Zhang ,  Yan Liu ,  Lixiang Ma

IPC分类号： C12N5/02 ,  C12N5/0793 ,  G01N33/50

CPC分类号： C12N5/0619 ,  C12N2501/01 ,  C12N2501/105 ,  C12N2501/115 ,  C12N2501/13 ,  C12N2501/15 ,  C12N2501/155 ,  C12N2501/392 ,  C12N2501/41 ,  C12N2502/086 ,  C12N2506/02 ,  C12N2506/45 ,  C12N2533/52 ,  G01N33/5058 ,  G01N2500/10

摘要： Methods of efficiently converting primate pluripotent stem cells to GABA neurons or cholinergic neurons, as well as applications thereof, are disclosed.

摘要翻译： 公开了将灵长类多能干细胞有效转化为GABA神经元或胆碱能神经元的方法及其应用。

公开(公告)号：US08879233B2

公开(公告)日：2014-11-04

申请号：US13266657

申请日：2010-05-13

申请人： Richard A. Cooke ,  Nate Richard ,  Steven Donnell ,  Mark Vose ,  Yan Liu

发明人： Richard A. Cooke ,  Nate Richard ,  Steven Donnell ,  Mark Vose ,  Yan Liu

IPC分类号： H01T23/00 ,  H01L21/683 ,  H01L21/687

CPC分类号： H01L21/6831 ,  H01L21/6875

摘要： In accordance with an embodiment of the invention, there is provided an electrostatic chuck. The electrostatic chuck comprises a surface layer activated by a voltage in an electrode to form an electric charge to electrostatically clamp a substrate to the electrostatic chuck. The surface layer includes a plurality of polymer protrusions and a charge control layer to which the plurality of polymer protrusions adhere, the plurality of polymer protrusions extending to a height above portions of the charge control layer surrounding the plurality of polymer protrusions to support the substrate upon the plurality of polymer protrusions during electrostatic clamping of the substrate.

摘要翻译： 根据本发明的实施例，提供了一种静电卡盘。 静电卡盘包括由电极中的电压激活的表面层，以形成电荷以将基板静电夹持到静电卡盘。 表面层包括多个聚合物突起和电荷控制层，多个聚合物突起粘附在该电荷控制层上，多个聚合物突起延伸到围绕多个聚合物突起的电荷控制层的部分上方的高度，以将基底支撑在 在基板的静电夹持期间的多个聚合物突起。

公开(公告)号：US20140252316A1

公开(公告)日：2014-09-11

申请号：US14238775

申请日：2012-10-03

申请人： Hao Yan ,  Zhengtao Deng ,  Yan Liu

发明人： Hao Yan ,  Zhengtao Deng ,  Yan Liu

IPC分类号： H01L29/06 ,  H01L29/775 ,  H01L29/66

CPC分类号： C09K11/883 ,  B82Y5/00 ,  B82Y10/00 ,  B82Y15/00 ,  B82Y30/00 ,  B82Y40/00 ,  C01B19/002 ,  C01B19/007 ,  C01G9/08 ,  C01G19/00 ,  C01P2002/72 ,  C01P2002/84 ,  C01P2002/85 ,  C01P2004/04 ,  C01P2004/16 ,  C01P2004/17 ,  C01P2004/64 ,  C01P2004/86 ,  C01P2004/88 ,  C09K11/02 ,  C09K11/08 ,  C09K11/0811 ,  C09K11/54 ,  C09K11/565 ,  C09K11/574 ,  C09K11/661 ,  G01N33/588 ,  H01B1/02 ,  H01L29/0669 ,  H01L29/122 ,  H01L29/127 ,  H01L29/22 ,  H01L29/66977 ,  H01L29/775 ,  Y10T428/12431 ,  Y10T428/294

摘要： Described are ZnxCd1-xSySe1-y/ZnSzSe1-z core/shell nanocrystals, CdTe/CdS/ZnS core/shell/shell nanocrystals, optionally ally doped Zn(S,Se,Te) nano- and quantum wires, and SnS quantum sheets or ribbons, methods for making the same, and their use in biomedical and photonic applications, such as sensors for analytes in cells and preparation of field effect transistors.

摘要翻译： 描述了ZnxCd1-xSySe1-y / ZnSzSe1-z核/壳纳米晶体，CdTe / CdS / ZnS核/壳/壳纳米晶体，任选地掺杂Zn（S，Se，Te）纳米和量子线，以及SnS量子片或 丝带，制造方法，以及它们在生物医学和光子应用中的应用，如细胞中分析物的传感器和场效应晶体管的制备。

公开(公告)号：US08738361B2

公开(公告)日：2014-05-27

申请号：US12496252

申请日：2009-07-01

申请人： Wojciech Gryc ,  Richard Lawrence ,  Yan Liu

发明人： Wojciech Gryc ,  Richard Lawrence ,  Yan Liu

IPC分类号： G06F17/27

CPC分类号： G06F17/27 ,  G06F17/2745

摘要： A computing system receives input data having both graph and unstructured data and computes a current log likelihood of the input data. The computing system compares the current log likelihood with a previous log likelihood of the input data. If the current log likelihood is larger than the previous log likelihood, the computing system update topic modeling parameters, community modeling parameters, and the link generation parameter until the computing system obtains a maximal value of the log likelihood of the input data. Then, the computing system creates a graph indicating topic similarity between the input data based on the topic modeling parameters, creates another graph indicating community similarity between entities associated with the input data based on the community modeling parameters, and predicts a link existence between input data or entities based on the link generation parameter, the topic modeling parameter and the community modeling parameter.

摘要翻译： 计算系统接收具有图形和非结构化数据的输入数据，并计算输入数据的当前对数似然性。 计算系统将当前对数似然率与输入数据的先前对数似然比较。 如果当前对数似然度大于先前的对数似然度，则计算系统更新主题建模参数，社区建模参数和链路生成参数，直到计算系统获得输入数据的对数似然性的最大值。 然后，计算系统基于主题建模参数创建指示输入数据之间的主题相似性的图形，基于社区建模参数创建指示与输入数据相关联的实体之间的社区相似性的另一图形，并且预测输入数据之间的链接存在 或基于链接生成参数，主题建模参数和社区建模参数的实体。

公开(公告)号：US20140036462A1

公开(公告)日：2014-02-06

申请号：US13564730

申请日：2012-08-02

申请人： Ruonan Wang ,  Yan Liu ,  Song He ,  Tingting Wang

发明人： Ruonan Wang ,  Yan Liu ,  Song He ,  Tingting Wang

IPC分类号： H05K1/16 ,  H05K3/42

CPC分类号： H01L23/49822 ,  H01L23/147 ,  H01L23/49816 ,  H01L23/49827 ,  H01L23/642 ,  H01L23/645 ,  H01L25/16 ,  H01L27/016 ,  H01L27/0694 ,  H01L28/10 ,  H01L2223/6677 ,  H01L2224/0401 ,  H01L2224/04042 ,  H01L2224/05554 ,  H01L2224/05568 ,  H01L2224/0557 ,  H01L2224/16145 ,  H01L2224/16225 ,  H01L2224/48227 ,  H01L2924/00014 ,  H01L2924/15311 ,  H01L2924/19041 ,  H01L2924/19042 ,  H01L2924/19104 ,  H01L2924/19105 ,  H01L2924/30107 ,  Y10T29/49165 ,  H01L2924/00 ,  H01L2224/05552

摘要： The present invention relates to a device with portions of the device on plural substrate surfaces. The device includes a low resistivity substrate having first and second surfaces with a first electrically-conductive device component disposed over a first surface. An intermediate electrically-insulating layer may be disposed between the electrically-conductive component and the low resistivity substrate. A second electrically-conductive component is disposed over the second surface of the low resistivity substrate. A cavity formed in the low resistivity substrate is at least partially filled with a high resistivity material. One or more electrically-conducting pathways are formed in the high resistivity material electrically connecting the first electrically conductive component and the second electrically-conductive component to form a device. Exemplary devices include inductors, capacitors, antennas and active or passive devices incorporating such devices. Vertically integrated device systems can be formed using the device.

摘要翻译： 本发明涉及一种在多个基板表面上具有该装置的部分的装置。 该器件包括具有第一和第二表面的低电阻率衬底，其具有设置在第一表面上的第一导电器件部件。 中间电绝缘层可以设置在导电部件和低电阻率基板之间。 第二导电部件设置在低电阻率基板的第二表面上。 形成在低电阻率衬底中的空腔至少部分地被高电阻率材料填充。 在高电阻率材料中形成一个或多个导电通路，电连接第一导电部件和第二导电部件以形成器件。 示例性器件包括电感器，电容器，天线以及并入这种器件的有源或无源器件。 可以使用该装置形成垂直集成的装置系统。

公开(公告)号：US20130346928A1

公开(公告)日：2013-12-26

申请号：US13977205

申请日：2011-06-25

申请人： Kenli Li ,  Zhimin Zhang ,  Yan Liu ,  Zhuo Tang ,  Yun-chuan Qin ,  Degui Xiao

发明人： Kenli Li ,  Zhimin Zhang ,  Yan Liu ,  Zhuo Tang ,  Yun-chuan Qin ,  Degui Xiao

IPC分类号： G06F17/50

CPC分类号： G06F17/5045 ,  G06F21/75

摘要： A method for protecting Register Transfer Level (RTL) Intellectual Property (IP) core is provided, which converts an original RTL IP core to a target RTL IP core embedded with protection measures. The method includes: Step S1, constructing a state machine whose mode is controllable against the original RTL IP core, the state machine has a normal mode appeared corresponding to the normal function of the IP core after the entry of a correct preset secret key value and a fuzzy mode appeared corresponding to the abnormal function of the IP core after the entry of wrong secret key value; Step S2, revise the data flow of the RTL code in the original RTL IP core to obtain the fuzzy RTL code of the IP core; and Step S3: combine the state machine and the fuzzy RTL code into the targeted RTL IP core. By combining the secret key control and fuzzy data flow, the being embezzled and reverse-engineered of RTL IP core can be effectively prevented.

摘要翻译： 提供了一种保护注册转移级别（RTL）知识产权（IP）核心的方法，将原始RTL IP内核转换为嵌入有保护措施的目标RTL IP内核。 该方法包括：步骤S1，构建模式对原始RTL IP核可控制的状态机，在输入正确的预设密钥值后，状态机具有对应于IP核的正常功能的正常模式， 在输入错误的密钥值后，对应于IP核的异常功能出现模糊模式; 步骤S2，修改原始RTL IP核中的RTL码的数据流，得到IP核的模糊RTL码; 步骤S3：将状态机和模糊RTL代码组合到目标RTL IP内核中。 通过组合秘密密钥控制和模糊数据流，可以有效防止RTL IP内核被贪污和反向设计。

公开(公告)号：US20130329320A1

公开(公告)日：2013-12-12

申请号：US13548586

申请日：2012-07-13

申请人： Zhao yu Teng ,  Chong Xi Song ,  Yun Zhang ,  Yan Liu

发明人： Zhao yu Teng ,  Chong Xi Song ,  Yun Zhang ,  Yan Liu

IPC分类号： G11B5/48

CPC分类号： H05K1/0248 ,  G11B5/484 ,  G11B5/4853 ,  G11B5/486 ,  H05K1/0245 ,  H05K2201/09245 ,  H05K2201/097

摘要： A suspension includes a positive write trace and a negative write trace. The positive write trace is separated into at least two positive write trace sections located at two different layers respectively, and the negative write trace is separated into at least two negative write trace sections located at two different layers respectively. Each positive write trace section and each negative write trace section are alternately arranged along a longitudinal direction on two different layers, and the positive write trace sections at different layers are connected together via conductive crossovers, and the negative write trace sections are connected together via conductive crossovers. The present invention can obtain balanced propagation time in the stacked trace structure to reduce signal distortion, and obtain widened frequency bandwidth.

摘要翻译： 暂停包括正写入跟踪和负写入跟踪。 正写入迹线分成至少两个位于两个不同层的正写入跟踪部分，负写入跟踪分别分成位于两个不同层的至少两个负写入跟踪部分。 每个正写入跟踪部分和每个负写入跟踪部分沿着两个不同层的纵向方向交替布置，并且不同层的正写入跟踪部分经由导电交叉连接在一起，并且负写入跟踪部分通过导电连接在一起 交叉 本发明可以在堆叠轨迹结构中获得平衡的传播时间，以减少信号失真，并获得扩大的频带宽度。

公开(公告)号：US08521745B2

公开(公告)日：2013-08-27

申请号：US13158678

申请日：2011-06-13

申请人： Katharina Probst ,  Rayid Ghani ,  Andrew E. Fano ,  Marko Krema ,  Yan Liu

发明人： Katharina Probst ,  Rayid Ghani ,  Andrew E. Fano ,  Marko Krema ,  Yan Liu

IPC分类号： G06F17/30

CPC分类号： G06F17/2715 ,  G06F17/241 ,  G06F17/30616

摘要： One or more classification algorithms are applied to at least one natural language document in order to extract both attributes and values of a given product. Supervised classification algorithms, semi-supervised classification algorithms, unsupervised classification algorithms or combinations of such classification algorithms may be employed for this purpose. The at least one natural language document may be obtained via a public communication network. Two or more attributes (or two or more values) thus identified may be merged to form one or more attribute phrases or value phrases. Once attributes and values have been extracted in this manner, association or linking operations may be performed to establish attribute-value pairs that are descriptive of the product. In a presently preferred embodiment, an (unsupervised) algorithm is used to generate seed attributes and values which can then support a supervised or semi-supervised classification algorithm.

摘要翻译： 一个或多个分类算法被应用于至少一个自然语言文档，以便提取给定产品的属性和值。 为此，可以采用监督分类算法，半监督分类算法，无监督分类算法或这种分类算法的组合。 可以经由公共通信网络获得至少一个自然语言文档。 如此识别的两个或多个属性（或两个或多个值）可以被合并以形成一个或多个属性短语或值短语。 一旦以这种方式提取了属性和值，就可以执行关联或链接操作来建立描述产品的属性值对。 在当前优选的实施例中，（无监督）算法用于生成种子属性和值，然后可以支持受监督或半监督分类算法。

公开(公告)号：US08505047B2

公开(公告)日：2013-08-06

申请号：US12951014

申请日：2010-11-20

申请人： Yan Liu ,  Bhavan Ghandhi ,  Srinivasa C. Samudrala ,  Kabe Vanderbaan ,  Jing Zhang

发明人： Yan Liu ,  Bhavan Ghandhi ,  Srinivasa C. Samudrala ,  Kabe Vanderbaan ,  Jing Zhang

IPC分类号： H04N7/10 ,  H04N7/025

CPC分类号： H04N21/47202 ,  H04N21/2541 ,  H04N21/274 ,  H04N21/8355

摘要： A content provider broadcasts content to subscribers through a content distribution system. The content distribution system operator can capture broadcast content in accordance with policies established by the content provider and make the content available subsequent to the original broadcast in accordance with applicable business policies. Business policies are created by the content provider by modifying template information models which have associated rules. The content distributor stores the business policies and evaluates rules indicated by the business policies against attributes of a content asset to determine availability of the content asset.

摘要翻译： 内容提供者通过内容分发系统向用户广播内容。 内容分发系统运营商可以根据内容提供商建立的策略捕获广播内容，并根据适用的业务策略使原始广播之后的内容可用。 业务策略由内容提供商通过修改具有关联规则的模板信息模型来创建。 内容分发者存储业务策略并根据业务策略指示的规则对内容资产的属性进行评估，以确定内容资产的可用性。