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公开(公告)号：US20230312490A1
公开(公告)日：2023-10-05
申请号：US18181336
申请日：2023-03-09
Applicant: Gilead Sciences, Inc.
Inventor： Hang Chu , Juan A. Guerrero , Anna E. Hurtley , Tae H. Hwang , Lan Jiang , Darryl Kato , Tetsuya Kobayashi , John E. Knox , Scott E. Lazerwith , Xiaofen Li , David W. Lin , Jonathan W. Medley , Michael L. Mitchell , Devan Naduthambi , Zachary Newby , Neil H. Squires , Vickie H. Tsui , Chandrasekar Venkataramani , William J. Watkins , Hong Yang
IPC: C07D267/20 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D498/04
CPC classification number: C07D267/20 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D498/04 , A61K45/06
Abstract: The present disclosure generally relates to compounds and pharmaceutical compositions that may be used in methods of treating cancer.
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公开(公告)号：US20230248753A1
公开(公告)日：2023-08-10
申请号：US18304270
申请日：2023-04-20
Applicant: Gilead Sciences, Inc.
Inventor： Scott E. Lazerwith , Jonathan William Medley , Philip A. Morganelli , Thomas P. Stratton , Peiyuan Wang
IPC: A61K31/685
CPC classification number: A61K31/685
Abstract: Compounds and methods of using said compounds, alone or in combination with additional agents, and pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号：US11661431B2
公开(公告)日：2023-05-30
申请号：US17721636
申请日：2022-04-15
Applicant: Gilead Sciences, Inc.
Inventor： Stephen E. Ammann , Eda Y. Canales , Weng K. Chang , Henok H. Kinfe , Scott E. Lazerwith , Michael L. Mitchell , Yasamin Moazami , Scott D. Schroeder , Daniel G. Shore , Christopher J. Swank
IPC: C07D519/00 , C07D495/04 , A61P29/00
CPC classification number: C07D519/00 , C07D495/04
Abstract: The present disclosure relates generally to certain compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of an autoimmune disease and/or inflammatory condition, including systemic lupus erythematosus and cutaneous lupus erythematosus.
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公开(公告)号：US11643400B2
公开(公告)日：2023-05-09
申请号：US17171201
申请日：2021-02-09
Applicant: Gilead Sciences, Inc.
Inventor： Hang Chu , Juan A. Guerrero , Anna E. Hurtley , Tae H. Hwang , Lan Jiang , Darryl Kato , Tetsuya Kobayashi , John E. Knox , Scott E. Lazerwith , Xiaofen Li , David W. Lin , Jonathan W. Medley , Michael L. Mitchell , Devan Naduthambi , Zachary Newby , Neil H. Squires , Vickie H. Tsui , Chandrasekar Venkataramani , William J. Watkins , Hong Yang
IPC: C07D513/08 , A61K31/553 , C07D267/20 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D498/04 , A61K45/06
CPC classification number: C07D267/20 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D498/04 , A61K45/06
Abstract: The present disclosure generally relates to compounds and pharmaceutical compositions that may be used in methods of treating cancer.
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公开(公告)号：US10988451B2
公开(公告)日：2021-04-27
申请号：US16857021
申请日：2020-04-23
Applicant: Gilead Sciences, Inc.
Inventor： Hang Chu , Juan A. Guerrero , Anna E. Hurtley , Tae H. Hwang , Lan Jiang , Darryl Kato , Tetsuya Kobayashi , John E. Knox , Scott E. Lazerwith , Xiaofen Li , David W. Lin , Jonathan W. Medley , Michael L. Mitchell , Devan Naduthambi , Zachary Newby , Neil H. Squires , Vickie H. Tsui , Chandrasekar Venkataramani , William J. Watkins , Hong Yang
IPC: C07D513/08 , A61K31/553 , C07D267/20 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D498/04 , A61K45/06
Abstract: The present disclosure generally relates to compounds and pharmaceutical compositions that may be used in methods of treating cancer.
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Patent Agency Ranking
公开(公告)号：US20210015816A1
公开(公告)日：2021-01-21
申请号：US16832230
申请日：2020-03-27
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Zhenhong R. Cai , Jeromy J. Cottell , Mingzhe Ji , Haolun Jin , Scott E. Lazerwith , Philip Anthony Morganelli , Hyung-Jung Pyun
IPC: A61K31/4985 , C07D471/04 , C07D491/147 , C07D491/20 , A61K45/06
Abstract: Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (Ia): including stereoisomers and pharmaceutically acceptable salts thereof, wherein A′, R1, R2 and R3 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
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![Substituted 3,4,5,6,8,10,14,14a-octahydro-2h-2,6-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazocines and methods for treating viral infections](/abs-image/US/2020/06/23/US10689399B2/abs.jpg.150x150.jpg)
公开(公告)号：US10689399B2
公开(公告)日：2020-06-23
申请号：US16017371
申请日：2018-06-25
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Zhenhong R. Cai , Xiaowu Chen , Jeromy J. Cottell , Manoj C. Desai , Mingzhe Ji , Haolun Jin , Scott E. Lazerwith , Michael R. Mish , Philip Anthony Morganelli , Hyung-Jung Pyun , James G. Taylor , Teresa Alejandra Trejo Martin
IPC: A61K31/4985 , C07D413/14 , C07D498/14 , A61K31/537 , C07D471/22 , A61K31/529 , A61K31/551 , A61K31/498 , C07D471/18 , A61K45/06 , C07D498/18 , C07D487/14 , A61K31/553
Abstract: Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, X, W, Y1, Y2, Z1, and Z4 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
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公开(公告)号：US20200061024A1
公开(公告)日：2020-02-27
申请号：US16403247
申请日：2019-05-03
Applicant: GILEAD SCIENCES, INC.
Inventor： Jinfa Du , Joshua A. Kaplan , Thorsten A. Kirschberg , Tetsuya Kobayashi , Scott E. Lazerwith , Rick Andrew Lee , Jonathan William Medley , Michael L. Mitchell , Philip Anthony Morganelli , Hyung-Jung Pyun , Sophia L. Shevick , Neil H. Squires , William J. Watkins
IPC: A61K31/403 , A61K31/4192 , A61K31/38 , A61K31/16 , A61K31/03 , A61P31/20 , C07D519/00 , C07D487/04
Abstract: This application relates generally to certain substituted pyrrolizine compounds, and pharmaceutical compositions which inhibit HBV replication, and methods of making and using them.
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公开(公告)号：US20180273508A1
公开(公告)日：2018-09-27
申请号：US15910083
申请日：2018-03-02
Applicant: Gilead Sciences, Inc.
Inventor： Gediminas Brizgys , Eda Canales , Chien-Hung Chou , Michael Graupe , Randall L. Halcomb , Yunfeng Eric Hu , Scott E. Lazerwith , John O. Link , Qi Liu , Yafan Lu , Roland D. Saito , Scott D. Schroeder , John R. Somoza , Winston C. Tse , Jennifer R. Zhang
IPC: C07D401/12 , C07D487/04 , A61K31/517 , A61K31/496 , A61K31/4725 , C07D491/052 , A61K31/4439 , A61K31/437 , A61K45/06 , A61K31/444 , A61K31/5377 , C07D401/14 , C07D403/14 , C07D471/04 , C07D401/04 , C07D417/14 , C07D413/14 , A61K31/506
CPC classification number: C07D401/12 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4725 , A61K31/496 , A61K31/506 , A61K31/517 , A61K31/5377 , A61K45/06 , C07D401/04 , C07D401/14 , C07D403/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D491/052
Abstract: Compounds of formula (I) or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.
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公开(公告)号：US09951043B2
公开(公告)日：2018-04-24
申请号：US14771779
申请日：2014-02-28
Applicant: Gilead Sciences, Inc.
Inventor： Gediminas Brizgys , Eda Canales , Chien-hung Chou , Michael Graupe , Randall L. Halcomb , Yunfeng Eric Hu , Scott E. Lazerwith , John O. Link , Qi Liu , Yafan Lu , Roland D. Saito , Scott D. Schroeder , John R. Somoza , Winston C. Tse , Jennifer R. Zhang
IPC: C07D401/12 , C07D401/04 , C07D487/04 , C07D413/14 , C07D491/052 , C07D417/14 , C07D401/14 , C07D471/04 , C07D403/14 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4725 , A61K31/496 , A61K31/506 , A61K31/517 , A61K31/5377 , A61K45/06
CPC classification number: C07D401/12 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4725 , A61K31/496 , A61K31/506 , A61K31/517 , A61K31/5377 , A61K45/06 , C07D401/04 , C07D401/14 , C07D403/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D491/052
Abstract: Compounds of formula (I) or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.
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