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公开(公告)号:US20060167070A1
公开(公告)日:2006-07-27
申请号:US11282119
申请日:2005-11-17
申请人: Weiwen Ying , David James , Shijie Zhang , Teresa Przewloka , Junghyun Chae , Dinesh Chimmanamada , Chi-Wan Lee , Elena Kostik , Howard Ng , Kevin Foley , Zhenjian Du , James Barsoum
发明人: Weiwen Ying , David James , Shijie Zhang , Teresa Przewloka , Junghyun Chae , Dinesh Chimmanamada , Chi-Wan Lee , Elena Kostik , Howard Ng , Kevin Foley , Zhenjian Du , James Barsoum
IPC分类号: A61K31/4196 , C07D403/02 , C07D249/12 , C07D249/08
CPC分类号: C07D249/08 , A61K31/4196 , C07D249/12 , C07D401/04 , C07D403/04 , C07D403/10 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D473/00 , C07D473/34
摘要: The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
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公开(公告)号:US20050268020A1
公开(公告)日:2005-12-01
申请号:US10856897
申请日:2004-05-27
申请人: David James
发明人: David James
CPC分类号: G06F13/387 , G06F13/409
摘要: A data transfer system has a bus having a plurality of bus lines, with the bus lines including at least a first and a second group of signal lines and at least a first and a second clock line. A host device is coupled to the plurality of bus lines. A first connector generates and outputs a first source synchronous signal on the first clock line and a first plurality of data signals on the first group and a second connector generates and outputs a second source synchronous signal on the second clock line and a second plurality of data signals on the second group. The host device is operable to respond to the first and second source synchronous signals and the first and second plurality of data signals to latch the first plurality of data signals with the first source synchronous signal and to latch the second plurality of data signals with the second source synchronous signal.
摘要翻译: 数据传输系统具有总线,其具有多条总线,其中总线包括至少第一和第二组信号线以及至少第一和第二时钟线。 主机设备耦合到多条总线。 第一连接器在第一时钟线上产生并输出第一源同步信号,并且在第一组上产生第一多个数据信号,而第二连接器产生并在第二时钟线上输出第二源同步信号,并输出第二多个数据 信号在第二组。 所述主机设备可操作以响应于所述第一和第二源同步信号以及所述第一和第二多个数据信号以用所述第一源同步信号锁存所述第一多个数据信号,并且用所述第二源同步信号锁存所述第二多个数据信号 源同步信号。
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公开(公告)号:US20050020082A1
公开(公告)日:2005-01-27
申请号:US10922715
申请日:2004-08-20
申请人: Arun Vishwanathan , David James , Lee Cook , Peter Burke , David Shidner
发明人: Arun Vishwanathan , David James , Lee Cook , Peter Burke , David Shidner
IPC分类号: B24B37/04 , B24D3/28 , B24D13/14 , B24B49/00 , B24B51/00 , H01L21/302 , H01L21/461
CPC分类号: B24B37/26 , B24B37/042 , B24D3/28
摘要: An improved pad and process for polishing metal damascene structures on a semiconductor wafer. The process includes the steps of pressing the wafer against the surface of a polymer sheet in combination with an aqueous-based liquid that optionally contains sub-micron particles and providing a means for relative motion of wafer and polishing pad under pressure so that the moving pressurized contact results in planar removal of the surface of said wafer, wherein the polishing pad has a low elastic recovery when said load is removed, so that the mechanical response of the sheet is largely anelastic. The improved pad is characterized by a high energy dissipation coupled with a high pad stiffness. The pad exhibits a stable morphology that can be reproduced easily and consistently. The pad surface resists glazing, thereby requiring less frequent and less aggressive conditioning. The benefits of such a polishing pad are low dishing of metal features, low oxide erosion, reduced pad conditioning, longer pad life, high metal removal rates, good planarization, and lower defectivity (scratches and Light Point Defects).
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公开(公告)号:US06784144B2
公开(公告)日:2004-08-31
申请号:US10068365
申请日:2002-02-05
申请人: David James
发明人: David James
IPC分类号: A61K700
摘要: The invention describes a silicone oil emulsion stabilized with soap. The soap is formed in situ from one or more fatty acids and a cation of a base during the emulsification process. The invention also provides a method of forming a soap stabilized oil-in-water emulsion including the steps of forming a first mixture comprising a silicone oil, a base, and initial water, combining the first mixture with a fatty acid component and emulsifying the resultant combination.
摘要翻译: 本发明描述了用肥皂稳定的硅油乳液。 肥皂在乳化过程中由一种或多种脂肪酸和碱的阳离子原位形成。本发明还提供一种形成皂稳定的水包油乳液的方法,包括以下步骤:形成第一混合物,其包含 硅油,碱和初始水,将第一混合物与脂肪酸组分组合并将所得组合物乳化。
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公开(公告)号:US06743919B2
公开(公告)日:2004-06-01
申请号:US10233371
申请日:2002-08-29
申请人: Keizo Koya , Lijun Sun , Mitsunori Ono , David James , Weiwen Ying , Shoujun Chen
发明人: Keizo Koya , Lijun Sun , Mitsunori Ono , David James , Weiwen Ying , Shoujun Chen
IPC分类号: C07D47102
CPC分类号: C07D231/12 , C07D233/56 , C07D249/08 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/14 , C07D471/04
摘要: Disclosed is a compound represented by Structural Formula (I): R1 is a substituted or unsubstituted 2-imidazolyl group which is optionally fused to a substituted or unsubstituted aryl group. Z1 is ═O, ═S, ═NOR11, or ═NR11. R is represented by a Structural Formula selected from (II)-(VII): The variables in Structural Formulas (II)-(VII) are described below.
摘要翻译: 公开了由结构式(I)表示的化合物:R1是任选地与取代或未取代的芳基稠合的取代或未取代的2-咪唑基.Z1 = O,= S,= NOR11或= NR11.R 由选自(II) - (VII)的结构式表示:结构式(II) - (VII)中的变量如下所述。
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公开(公告)号:US06358898B1
公开(公告)日:2002-03-19
申请号:US09581578
申请日:2000-07-25
申请人: David James
发明人: David James
IPC分类号: A61K750
摘要: The invention describes a silicone oil emulsion stabilized with soap. The soap is formed in situ from one or more fatty acids and a cation of a base during the emulsification process. The invention also provides a method of forming a soap stabilized oil-in-water emulsion including the steps of forming a first mixture comprising a silicone oil, a base, and initial water, combining the first mixture with a fatty acid component and emulsifying the resultant combination.
摘要翻译: 本发明描述了用肥皂稳定的硅油乳液。 肥皂在乳化过程中由一种或多种脂肪酸和碱的阳离子原位形成。本发明还提供一种形成皂稳定的水包油乳液的方法,包括以下步骤:形成第一混合物,其包含 硅油,碱和初始水,将第一混合物与脂肪酸组分组合并将所得组合物乳化。
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公开(公告)号:US10126803B1
公开(公告)日:2018-11-13
申请号:US13079538
申请日:2011-04-04
申请人: Ryan Cairns , Sameer Nanda , Benson Leung , David James
发明人: Ryan Cairns , Sameer Nanda , Benson Leung , David James
IPC分类号: G06F1/32
摘要: Methods and apparatus for scheduling and controlling power management activities are disclosed. An example method includes detecting, by a computing device, playback of video content at a frame rate that is greater than a predetermined threshold frame rate. The example method further includes, in response to the detection of the playback of video content at the frame rate greater than the threshold frame rate, overriding a screen dimming operation of the computing device.
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公开(公告)号:US08648071B2
公开(公告)日:2014-02-11
申请号:US13001255
申请日:2009-06-26
IPC分类号: A61K31/5375 , A61K31/5377 , A61K31/445 , A61K31/357 , C07D413/00 , C07D413/02 , C07D295/00 , C07D211/00 , C07D317/46
CPC分类号: C07C257/22 , C07D213/74 , C07D317/58 , C07D317/66
摘要: The present invention relates to substituted hydrazonamide compounds. The invention further relates to methods of inhibiting the activity of Hsρ90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted hydrazonamide compound of the invention, or a pharmaceutical composition comprising such a compound.
摘要翻译: 本发明涉及取代的酰胺化合物。 本发明还涉及在有需要的受试者中抑制Hshoho90活性的方法和在有需要的受试者中治疗过度增殖性疾病如癌症的方法,其包括向受试者施用本发明的取代的酰胺化合物或 包含这种化合物的药物组合物。
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公开(公告)号:US08554889B2
公开(公告)日:2013-10-08
申请号:US10926686
申请日:2004-08-26
申请人: Eric Holtz , David James , Michael Healy
发明人: Eric Holtz , David James , Michael Healy
IPC分类号: G06F15/173 , G06F15/16
CPC分类号: H04L41/12
摘要: Embodiments of the present invention provide the ability to accurately match a particular computing device within a networked computing environment with an identity of that computing device. According to one aspect, a method for identifying a client computing device in a networked computing environment is provided. The method receives a discovery data record that includes a hardware identification and a logical identification, and in response, queries a plurality of client records for a matching client record. If a matching client record is identified by the query it is compared with the received discovery data record to identify the client computing device.
摘要翻译: 本发明的实施例提供将网络计算环境中的特定计算设备与该计算设备的身份精确匹配的能力。 根据一个方面,提供了一种用于在网络计算环境中识别客户端计算设备的方法。 该方法接收包括硬件标识和逻辑标识的发现数据记录,作为响应,查询多个客户记录以获得匹配的客户端记录。 如果由查询识别匹配的客户端记录,则将其与接收到的发现数据记录进行比较以识别客户端计算设备。
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公开(公告)号:US20130142831A1
公开(公告)日:2013-06-06
申请号:US13652878
申请日:2012-10-16
申请人: Shoujun Chen , Jun Jiang , Hao Li , David James , Dinesh Chimmanamada , Christopher Borella , Lijun Sun , Yu Xie , Mats Holmqvist , Jerome Mahiou , Zhiqiang Xia
发明人: Shoujun Chen , Jun Jiang , Hao Li , David James , Dinesh Chimmanamada , Christopher Borella , Lijun Sun , Yu Xie , Mats Holmqvist , Jerome Mahiou , Zhiqiang Xia
IPC分类号: A61K31/437
CPC分类号: A61K31/437 , A61K31/403 , A61K31/4184 , A61K31/4439 , A61K31/444 , A61K31/537 , C07D235/06 , C07D235/08 , C07D235/10 , C07D235/24 , C07D235/28 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/04 , C07D413/14 , C07D417/12 , C07D471/04 , Y02A50/422
摘要: The invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof wherein X, Y, A, Z, L and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions and immune disorders.
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