POLYPEPTIDE POROUS BODY AND METHOD FOR PRODUCING SAME
    68.
    发明申请
    POLYPEPTIDE POROUS BODY AND METHOD FOR PRODUCING SAME 审中-公开
    多肽多孔体及其生产方法

    公开(公告)号:US20150361144A1

    公开(公告)日:2015-12-17

    申请号:US14764463

    申请日:2014-04-18

    Applicant: SPIBER INC.

    Abstract: A polypeptide porous body of the present invention is a porous body of a polypeptide derived from spider silk proteins. The polypeptide includes a water-insoluble polypeptide. The polypeptide porous body has an apparent density of 0.1 g/cm3 or less. A method for producing the polypeptide porous body includes: a solution production step in which the polypeptide is dissolved in at least one solvent selected from DMSO, DMF, and these with an inorganic salt, so as to obtain a solution of the polypeptide; a step in which the solution produced in the solution production step is substituted with a water-soluble solvent so as to obtain a polypeptide gel; and a step in which the polypeptide gel is dried. Thereby, the present invention provides a polypeptide porous body having excellent water absorbability and a polypeptide porous body suitable for application to a living body, and a method for producing the same.

    Abstract translation: 本发明的多肽多孔体是衍生自蜘蛛丝蛋白的多肽的多孔体。 多肽包括水不溶性多肽。 多孔多孔体的表观密度为0.1g / cm 3以下。 制备多孔多孔体的方法包括:溶液制备步骤,其中将多肽溶解在至少一种选自DMSO,DMF的溶剂中,并用无机盐溶解,得到多肽的溶液; 在溶液制备工序中产生的溶液用水溶性溶剂代替以获得多肽凝胶的步骤; 以及其中多肽凝胶被干燥的步骤。 因此,本发明提供了具有优异的吸水性的多孔多孔体和适用于生物体的多孔多孔体及其制造方法。

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