摘要:
An optical scanning device for scanning a dual-layer optical record carrier. The device includes a spherical aberration compensation optical subsystem having a switchable liquid crystal cell (10) for altering a wavefront deviation generated in a folding mirror (32) including a non-periodic phase structure (NPS) located behind a polarization-selective reflective layer.
摘要:
A device for scanning a first and second type of optical record carriers (2, 40) generators a first and a second radiation beam for scanning the first and second type of record carriers, respectively. The information layers (4, 42) of the first and second type of record carriers is scanned through transparent layers (3, 41) of different thickness. The first radiation beam (17) has a first wavelength and a first numerical aperture NA−1. The second radiation beam (46) has a different, second wavelength and an effective second numerical aperture NA2 smaller NA1. The rays of the second radiation beam having an NA smaller than NA2 form a central sub-beam (48), the rays having a larger NA form an outer sub-beam (49). The device includes a non-periodic phase structure that does not affect the first radiation beam. The phase structure introduces an amount of spherical aberration in the central sub-beam (48). The phase structure is transparent for the central and outer sub-beam (48, 49). The introduced spherical aberration compensates the difference in spherical aberration caused by the difference in thickness of the transparent layer (3, 41) of the first and second type of record carriers (2, 40). To reduce the amount of stray light falling on the detection system (25) from rays in the outer sub-beam (49), the phase structure introduces an amount of defocus in the second radiation beam (17). The defocus displaces the focus of the central sub-beam with respect to the focus of the outer sub-beam, causing the intensity distribution of the central and outer sub-beam split in two separate distributions. If the position and size of the detection system are properly chosen, the detection system will capture mainly rays from the central sub-beam and not from the outer sub-beam. Hence, the displacement of the foci allows spatial filtering in the plane of the detection system (25) of the desired and undesired rays of the second radiation beam.
摘要:
Skin monitoring device for application near the skin includes a processing circuit and at least one photosensor configured to detect at least one approximate wavelength of light reflected and/or emitted by the skin. A signal receiving circuit receives signals from the photosensor.
摘要:
A needle device includes a hollow shaft, an elongated insert and an operating lever. The hollow shaft has a first distal end portion with a bevel, the elongated insert has a second distal end portion and is movably arranged within the hollow shaft, and the operating lever is shiftable between a first condition and a second condition. Furthermore, the operating lever is interconnected with the elongated insert such that the second distal end portion is located within the hollow shaft and proximally to the bevel when the operating lever is in the first condition, and that the second distal end portion is located outside the hollow shaft and distally to the bevel when the operating lever is in the second condition.
摘要:
A system for providing integrated guidance for positioning a needle in a body has two levels of guidance: a coarse guidance and a fine guidance. The system includes a non-invasive tracking system for tracing the biopsy device in the body, for providing the coarse guidance. Furthermore, the system includes an optical detector mounted on the needle for obtaining optical information discriminating tissue in the body, for providing the fine guidance.
摘要:
The invention relates an optical probe (1) suitable for non-linear optics such as two-photon imaging for medical purposes. The probe has an optical guide (2) and a lens system (6) positioned rigidly at an end portion (2a) of the optical guide. Additionally, a housing (3) with a cavity for the optical guide (2) and the lens system (6), the housing having at its distal end a transparent window (4), is comprised in the probe. The optical guide (2) with the lens system (6) is displaceably mounted within the housing, preferably in a transverse direction. Also, the housing (3) has an auxiliary, peripheral optical guide (5) optically connected to the transparent window (4). The invention is advantageous for obtaining an optical probe with a significantly larger collection efficiency. The optical probe may advantageous be applied in connection with two-photon spectroscopy where both ballisitic photons and diffusing fluorescence photons can be used in the detection of an event.
摘要:
An infrared radiant heating system for raising or maintaining a uniform core temperature of the body of a patient during surgery, substantially without affecting the temperature of the area surrounding the patient's body, includes an infrared radiant heater located near the patient to provide radiant heat to the entire body or one or more parts of the body of the patient. The system further includes a controller in communication with the heater for controlling the intensity level and distribution of intensity of the radiant heat on the patient's body such that the skin temperature of the patient's body is raised or maintained within a predetermined range resulting in the uniform core body temperature, substantially without affecting the temperature of the area surrounding the patient's body.
摘要:
The invention discloses an optical microscopy system (10) for stimulated emission depletion (STED) of an object (O). An optical element (6) is applied for focusing a first excitation (1) and a second depletion (2) beam on the object thereby defining a common optical path (OP) for both the first and the second beam. A phase modifying member (5) is inserted in the common optical path (OP), and the phase modifying member is optically arranged for leaving the wavefront of the first beam substantially unchanged, and for changing the wavefront of the second beam (2′) so as to create an undepleted region of interest (ROI) in the object. The first beam and the second beam have a common optical path because the phase modifying member adapts the wavefront or phase in such a way that it has no effect on the first beam, while on the second beam it gives rise to a wavefront, or phase change, resulting in a depleted region in the object (e.g. to the donut shaped spot) at the focal plane. The invention facilitates smaller and/or improved optical designs for STED microscopy; this is particularly relevant for medical in-vivo imaging, e.g. endoscopes and catheters.
摘要:
The invention relates to a property determination apparatus (1) for determining a property of an object (3). Optical sensing data being indicative of an optical property of the object and ultrasound sensing data being indicative of an ultrasound property of the object are generated, and a property determination unit (75) determines a property of the object based on at least one of the optical sensing data and the ultrasound sensing data. Since light and ultrasound have generally different penetration depths and scattering properties with respect to the object, a property of the object can be determined with good quality, even if the quality of one of the optical sensing data and the ultrasound sensing data is reduced by, for example, a relatively small penetration depth, or if one of the optical sensing data and the ultrasound sensing data is less suitable for determining a desired property of the object.
摘要:
A system (40) for diagnosis and staging of early stages of cancer in the tissue of a patient is provided. The system—is configured to combine information from a Polarized Light Scattering Spectroscopy measurement (70) having a first probe depth, and a Differential Path Length Spectroscopy measurement (60) having a second probe depth, wherein the second probe depth is set larger than' the first probe depth. By comparing the results of the Polarized Light Scattering Spectroscopy and Differential Path Length Spectroscopy measurements early stages of cancer, such as dysplasia may be detected. Also hyperplasia, carcinoma in situ, and carcinoma may be detected. A computer-readable medium, method and use are also provided.