Optical scanning device
    71.
    发明授权
    Optical scanning device 失效
    光学扫描装置

    公开(公告)号:US07126900B2

    公开(公告)日:2006-10-24

    申请号:US10497343

    申请日:2002-12-05

    IPC分类号: G11B7/00

    摘要: An optical scanning device for scanning a dual-layer optical record carrier. The device includes a spherical aberration compensation optical subsystem having a switchable liquid crystal cell (10) for altering a wavefront deviation generated in a folding mirror (32) including a non-periodic phase structure (NPS) located behind a polarization-selective reflective layer.

    摘要翻译: 一种用于扫描双层光学记录载体的光学扫描装置。 该装置包括球面像差补偿光学子系统,其具有用于改变在包括位于偏振选择反射层之后的非周期相位结构(NPS)的折叠镜(32)中产生的波前偏差的可切换液晶单元(10)。

    Compensating for sherical aberration induced when reading from optical record carriers with transparent layers of different thickness

    公开(公告)号:US06928043B2

    公开(公告)日:2005-08-09

    申请号:US10008196

    申请日:2001-11-08

    IPC分类号: G02B5/18 G11B7/00 G11B7/135

    摘要: A device for scanning a first and second type of optical record carriers (2, 40) generators a first and a second radiation beam for scanning the first and second type of record carriers, respectively. The information layers (4, 42) of the first and second type of record carriers is scanned through transparent layers (3, 41) of different thickness. The first radiation beam (17) has a first wavelength and a first numerical aperture NA−1. The second radiation beam (46) has a different, second wavelength and an effective second numerical aperture NA2 smaller NA1. The rays of the second radiation beam having an NA smaller than NA2 form a central sub-beam (48), the rays having a larger NA form an outer sub-beam (49). The device includes a non-periodic phase structure that does not affect the first radiation beam. The phase structure introduces an amount of spherical aberration in the central sub-beam (48). The phase structure is transparent for the central and outer sub-beam (48, 49). The introduced spherical aberration compensates the difference in spherical aberration caused by the difference in thickness of the transparent layer (3, 41) of the first and second type of record carriers (2, 40). To reduce the amount of stray light falling on the detection system (25) from rays in the outer sub-beam (49), the phase structure introduces an amount of defocus in the second radiation beam (17). The defocus displaces the focus of the central sub-beam with respect to the focus of the outer sub-beam, causing the intensity distribution of the central and outer sub-beam split in two separate distributions. If the position and size of the detection system are properly chosen, the detection system will capture mainly rays from the central sub-beam and not from the outer sub-beam. Hence, the displacement of the foci allows spatial filtering in the plane of the detection system (25) of the desired and undesired rays of the second radiation beam.

    Optical probe
    76.
    发明授权
    Optical probe 有权
    光探头

    公开(公告)号:US09131845B2

    公开(公告)日:2015-09-15

    申请号:US12810872

    申请日:2008-12-19

    摘要: The invention relates an optical probe (1) suitable for non-linear optics such as two-photon imaging for medical purposes. The probe has an optical guide (2) and a lens system (6) positioned rigidly at an end portion (2a) of the optical guide. Additionally, a housing (3) with a cavity for the optical guide (2) and the lens system (6), the housing having at its distal end a transparent window (4), is comprised in the probe. The optical guide (2) with the lens system (6) is displaceably mounted within the housing, preferably in a transverse direction. Also, the housing (3) has an auxiliary, peripheral optical guide (5) optically connected to the transparent window (4). The invention is advantageous for obtaining an optical probe with a significantly larger collection efficiency. The optical probe may advantageous be applied in connection with two-photon spectroscopy where both ballisitic photons and diffusing fluorescence photons can be used in the detection of an event.

    摘要翻译: 本发明涉及适用于非线性光学的光学探针(1),例如用于医疗目的的双光子成像。 探针具有光导件(2)和刚性地定位在光导的端部(2a)处的透镜系统(6)。 此外,具有用于光导(2)和透镜系统(6)的空腔的壳体(3),其外壳在其远端处具有透明窗口(4),其包括在探针中。 具有透镜系统(6)的光导(2)优选地在横向方向上可移动地安装在壳体内。 另外,壳体(3)具有与透明窗(4)光学连接的辅助外周光导(5)。 本发明有利于获得具有显着更大收集效率的光学探针。 结合双光子光谱可以有利地应用光探针,其中可以使用Ballisitic光子和扩散荧光光子来检测事件。

    Temperature control of patients during surgery
    77.
    发明授权
    Temperature control of patients during surgery 有权
    手术期间患者的温度控制

    公开(公告)号:US08812132B2

    公开(公告)日:2014-08-19

    申请号:US12440071

    申请日:2007-09-20

    IPC分类号: A61F7/00

    摘要: An infrared radiant heating system for raising or maintaining a uniform core temperature of the body of a patient during surgery, substantially without affecting the temperature of the area surrounding the patient's body, includes an infrared radiant heater located near the patient to provide radiant heat to the entire body or one or more parts of the body of the patient. The system further includes a controller in communication with the heater for controlling the intensity level and distribution of intensity of the radiant heat on the patient's body such that the skin temperature of the patient's body is raised or maintained within a predetermined range resulting in the uniform core body temperature, substantially without affecting the temperature of the area surrounding the patient's body.

    摘要翻译: 用于在手术期间升高或保持患者身体的均匀核心温度的红外辐射加热系统基本上不影响患者身体周围区域的温度,包括位于患者附近的红外辐射加热器,以向患者提供辐射热 整个身体或患者身体的一个或多个部分。 该系统还包括与加热器连通的控制器,用于控制患者身体上的辐射强度的强度水平和分布,使得患者身体的皮肤温度升高或维持在预定范围内,导致均匀的芯 体温,基本上不影响患者身体周围区域的温度。

    STIMULATED EMISSION DEPLETION (STED) MICROSCOPY SYSTEM
    78.
    发明申请
    STIMULATED EMISSION DEPLETION (STED) MICROSCOPY SYSTEM 审中-公开
    刺激排泄(STED)微观系统

    公开(公告)号:US20140145093A1

    公开(公告)日:2014-05-29

    申请号:US13522038

    申请日:2011-01-13

    IPC分类号: G02B21/00 G01N21/64

    摘要: The invention discloses an optical microscopy system (10) for stimulated emission depletion (STED) of an object (O). An optical element (6) is applied for focusing a first excitation (1) and a second depletion (2) beam on the object thereby defining a common optical path (OP) for both the first and the second beam. A phase modifying member (5) is inserted in the common optical path (OP), and the phase modifying member is optically arranged for leaving the wavefront of the first beam substantially unchanged, and for changing the wavefront of the second beam (2′) so as to create an undepleted region of interest (ROI) in the object. The first beam and the second beam have a common optical path because the phase modifying member adapts the wavefront or phase in such a way that it has no effect on the first beam, while on the second beam it gives rise to a wavefront, or phase change, resulting in a depleted region in the object (e.g. to the donut shaped spot) at the focal plane. The invention facilitates smaller and/or improved optical designs for STED microscopy; this is particularly relevant for medical in-vivo imaging, e.g. endoscopes and catheters.

    摘要翻译: 本发明公开了一种用于对象(O)的受激发射耗尽(STED)的光学显微镜系统(10)。 应用光学元件(6)用于将第一激励(1)和第二耗尽(2)光束聚焦在物体上,从而为第一和第二光束定义公共光路(OP)。 相位调整构件(5)被插入到公共光路(OP)中,并且相位修改构件被光学地布置成使第一光束的波前基本上不变,并且用于改变第二光束(2')的波前, 以便在对象中创建未被删除的兴趣区域(ROI)。 第一光束和第二光束具有共同的光路,因为相位修改构件以这样的方式适配波前或相位,使得其对第一光束没有影响,而在第二光束上,其产生波前或相位 改变,导致焦平面上的物体(例如,环形斑点)中的耗尽区域。 本发明有助于STED显微镜的更小和/或改进的光学设计; 这对于医学体内成像尤其重要,例如, 内窥镜和导管。