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公开(公告)号:US11680957B2
公开(公告)日:2023-06-20
申请号:US16772390
申请日:2018-02-12
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Alexander N. Govyadinov , Pavel Kornilovich , Diane R. Hammerstad
IPC: G05D7/06 , G01P5/20 , B01L3/00 , G01F1/7082 , G01F1/7084 , G01F1/7086
CPC classification number: G01P5/20 , B01L3/502715 , G01F1/7082 , G05D7/0676 , B01L2300/0627 , G01F1/7084 , G01F1/7086
Abstract: A microfluidic flow sensor may include a substrate having a microfluidic channel, an inert particle source to supply a fluid carrying an inert particle to the microfluidic channel and a sensor element along the microfluidic channel and spaced from the inert particle source. The sensor element outputs a signal based upon a sensed passage of the inert particle with respect to the sensor element. Portions of the microfluidic channel proximate the sensor element have a first size and wherein the inert particle provided by the inert particle source is to have a second size greater than one half the first size.
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公开(公告)号:US11325380B2
公开(公告)日:2022-05-10
申请号:US16605255
申请日:2018-07-17
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Pavel Kornilovich , Alexander Govyadinov , John Lahmann , Paul J. Benning
Abstract: An example device includes a first droplet ejector including a first nozzle to eject droplets of a first fluid, and a first target medium positioned relative to the first droplet ejector to receive the droplets of the first fluid from the first droplet ejector. The example device further includes a second droplet ejector in fluid communication with the first target medium to receive a second fluid from the first target medium. The second droplet ejector includes a second nozzle to eject droplets of the second fluid.
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公开(公告)号:US20210331468A1
公开(公告)日:2021-10-28
申请号:US16605255
申请日:2018-07-17
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Pavel Kornilovich , Alexander Govyadinov , John Lahmann , Paul J. Benning
Abstract: An example device includes a first droplet ejector including a first nozzle to eject droplets of a first fluid, and a first target medium positioned relative to the first droplet ejector to receive the droplets of the first fluid from the first droplet ejector. The example device further includes a second droplet ejector in fluid communication with the first target medium to receive a second fluid from the first target medium. The second droplet ejector includes a second nozzle to eject droplets of the second fluid.
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公开(公告)号:US20210138467A1
公开(公告)日:2021-05-13
申请号:US16605162
申请日:2018-01-24
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Viktor Shkolnikov , Alexander N. Govyadinov , Pavel Kornilovich
Abstract: An object focuser may include a substrate, a sample fluid passage supported by the substrate, a first inertial pump supported by the substrate to pump a sample fluid entraining an object through the sample fluid passage, a first sheath fluid passage, a second inertial pump supported by the substrate to pump a first sheath fluid through the first sheath fluid passage, a second sheath fluid passage and a second inertial pump supported by the substrate to pump a second sheath fluid through the second sheath fluid passage. The first sheath fluid passage and the second sheath fluid passage are connected to the sample fluid passage at a convergence on opposite sides of the sample fluid passage.
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公开(公告)号:US20210031192A1
公开(公告)日:2021-02-04
申请号:US16768857
申请日:2018-03-12
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Pavel Kornilovich , Ross Warner , Alexander Govyadinov
IPC: B01L3/00
Abstract: A microfluidic device may include a die package. The die package may include at least on fluidic die and an overmold material overmolding the fluidic die. The microfluidic device may also include a mesofluidic plate coupled to the die package. The mesofluidic plate includes at least one mesofluidic channel formed therein to fluidically couple the fluidic die.
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公开(公告)号:US10688772B2
公开(公告)日:2020-06-23
申请号:US15110753
申请日:2014-03-31
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Alejandro Manuel De Pena , Pavel Kornilovich , David H. Donovan
IPC: B29C67/00 , B33Y50/02 , B33Y30/00 , B29C64/40 , B29C64/00 , B29C64/165 , B29C64/386 , B33Y10/00 , B29K105/00
Abstract: A three-dimensional object may be generated. Coalescing agent may be selectively delivered on a portion of a first layer of build material on a support member or previous layer. Energy may be applied to the first layer to cause the portion of the first layer to coalesce and solidify. A second layer of the build material may be provided on the first layer. While the second layer does not have coalescing agent delivered thereon, energy may be applied to the second layer such that energy may propagate through the second layer to the first layer to cause the portion of the first layer to coalesce and further solidify.
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公开(公告)号:US10272691B2
公开(公告)日:2019-04-30
申请号:US15205900
申请日:2016-07-08
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Pavel Kornilovich , Alexander Govyadinov , David P. Markel , Erik D. Torniainen
Abstract: A network of microfluidic channels may include at least three loops interconnected at a junction. Each of the loops may include a fluid channel having a length extending from the junction to a second end; and a fluid actuator along the fluid channel and located at a first distance from junction along the length of the fluid channel and at a second distance less than the first distance from the second end. Activation of the fluid actuator of selected ones of the at least three loops may selectively produce net fluid flow in different directions about the loops. In one implementation, a fluid channel having a fluid actuator may have a bridging portion that extends over another fluid channel.
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公开(公告)号:US20190048309A1
公开(公告)日:2019-02-14
申请号:US16079482
申请日:2016-04-22
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Alexander Govyadinov , Erik D. Torniainen , David P. Markel , Pavel Kornilovich
Abstract: In an example implementation, a method of cell lysis includes moving cell fluid from a first reservoir through a microfluidic channel toward a second reservoir, activating a lysing element multiple times as a cell from the cell fluid passes through the microfluidic channel, and moving lysate fluid that results from the activating through the microfluidic channel and into the second reservoir.
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公开(公告)号:US10197188B2
公开(公告)日:2019-02-05
申请号:US15503664
申请日:2014-08-15
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Alexander Govyadinov , Erik D Torniainen , David P Markel , Pavel Kornilovich
Abstract: In an example implementation, a method of controlling a microfluidic valve includes activating a first inertial pump at a first frequency, and a second inertial pump at a second frequency to create a first fluid flow pattern within a microfluidic valve. The method also includes adjusting at least one of the first frequency and the second frequency to change the first fluid flow pattern to a second fluid flow pattern.
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公开(公告)号:US20180272340A1
公开(公告)日:2018-09-27
申请号:US15763402
申请日:2015-09-25
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Alexander Govyadinov , Erik D. Torniainen , Pavel Kornilovich , David P. Markel
IPC: B01L3/00
CPC classification number: B01L3/50273 , B01L3/502707 , B01L2300/0816 , B01L2300/0861 , B01L2400/043 , B01L2400/0436 , B01L2400/0439 , B01L2400/0442 , B01L2400/0481 , B01L2400/06
Abstract: Example fluidic channels for microfluidic devices are disclosed. In examples disclosed herein, an example microfluidic device includes a body having a microfluidic network. The microfluidic network includes a main fluid channel to transport a biological fluid from a first cavity of the microfluidic network to a second cavity of the microfluidic network. An auxiliary fluid channel is in fluid communication with to the main fluid channel. The auxiliary fluid channel has a first end and a second end. The first end is in fluid communication with the main fluid channel and the second end is spaced from the main fluid channel. A fluid actuator is positioned in the auxiliary fluid channel to induce fluid flow in the main fluid channel.
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