摘要:
Provided herein are methods for identifying risk of melanoma in a subject and/or subjects at risk of melanoma, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating melanoma, therapeutic methods for treating melanoma in a subject and compositions comprising one or more melanoma cells and one or more NRP1, NID2 or ENDO180 directed agents. These embodiments are based upon an analysis of polymorphic variations in a NRP1, NID2 or ENDO180 nucleic acid, exemplified by nucleotide sequences of SEQ ID NO: 1, 2 or 3.
摘要翻译:本文提供用于鉴定受试者和/或患有黑素瘤风险的受试者的黑素瘤风险的方法,用于实施该方法的试剂和试剂盒的方法,用于鉴定治疗黑素瘤的候选治疗剂的方法,用于治疗受试者的黑素瘤的治疗方法和包含 一种或多种黑素瘤细胞和一种或多种NRP1,NID2或ENDO180定向试剂。 这些实施方案基于NRP1,NID2或ENDO180核酸的多态性变异的分析,例如SEQ ID NO:1,2或3的核苷酸序列。
摘要:
Implementations of a tennis ball pickup tube attachment bag are provided. In some implementations, the tennis ball pickup tube attachment bag comprises one or more pieces of material attached together and forming an enclosed interior and a corresponding exterior. In some implementations, the tennis ball pickup tube attachment bag also comprises a first opening and a second opening into the enclosed interior. In some implementations, the tennis ball pickup tube attachment bag also comprises a first securing loop and a second securing loop. In some implementations, the tennis ball pickup tube attachment bag also comprises a first securing strap, a second securing strap, and a third securing strap.In some implementations, a method for using the tennis ball pickup tube attachment bag comprises coupling the tennis ball pickup tube to the tennis ball pickup tube attachment bag, attaching the first securing loop and the second securing loop respectively to the first retainer wing and the second retainer wing of the tennis ball pickup tube, attaching the first securing strap to the carry strap loop of the tennis ball pickup tube, and attaching the second securing strap and the third securing strap respectively across the length of the tennis ball pickup tube.
摘要:
The present disclosure provides for a system and method for detecting explosives and other materials in a sample scene. First interacted photons are produced from a target area wherein the first interacted photons are generated via solar radiation. The first interacted photons are assessed to thereby generate a SWIR hyperspectral image. The SWIR hyperspectral image is analyzed to identify an area of interest likely of comprising an explosive material. The area of interest is illuminated using laser light illumination to generate second interacted photons from the area of interest. These second interacted photons are assessed to determine whether it not an explosive material is present in the area of interest. The system and method may be configured in standoff, OTM, static and UGV configurations.
摘要:
A display for a transport unit. The transport unit includes a trailer that defines a space with at least one zone, and a vehicle that is attachable to the trailer. The vehicle has a passenger compartment and a rear view mirror. A sensor is in communication with the transport unit and senses a parameter of the transport unit. The transport unit also includes a housing that is coupled to the trailer, and that has a display with a screen configured to display the parameter. A controller is attached to the trailer and is in communication with the space. The controller is in electrical communication with the sensor and the display, and the controller is programmed to selectively switch the display between a forward view mode and a mirror view mode based on a relationship between the vehicle and the trailer.
摘要:
A display for a transport unit. The transport unit includes a vehicle, a trailer that defines a space, and a sensor that is in communication with the transport unit and that senses a parameter of the transport unit. The display unit includes a housing that is attachable to the trailer, and a display portion coupled to the housing. The display portion includes a screen configured to display the parameter. A controller is in electrical communication with the display portion to display the parameter on the screen. The controller is programmed to selectively switch the screen between a forward view mode and a mirror view mode such that the parameter is readable on the screen from outside the vehicle and from inside the vehicle based on a relationship between the vehicle and the trailer.
摘要:
Some embodiments of a system for partitioning cargo spaces in a temperature-controlled cargo container can include one or more longitudinal panel assemblies with a user-selectable height feature. In such circumstances, a user can readily adjust the overall height of each longitudinal panel assembly while the longitudinal panel assembly is in the trailer so as to accommodate the interior height of the trailer (which might vary from trailer to trailer).
摘要:
A chemical imaging system is provided which uses a near infrared radiation microscope. The system includes an illumination source which illuminates an area of a sample using light in the near infrared radiation wavelength and light in the visible wavelength. A multitude of spatially resolved spectra of transmitted, reflected, or emitted or scattered near infrared wavelength radiation light from the illuminated area of the sample is collected and a collimated beam is produced therefrom. A near infrared imaging spectrometer is provided for selecting a near infrared radiation images of the collimated beam. The spectrometer comprises a liquid crystal tunable filter. The filtered selected images are collected by a detector for further processing. The visible wavelength light from the illuminated area of the sample is simultaneously detected providing for the simultaneous visible and near infrared chemical imaging analysis of the sample. Two efficient means for performing three dimensional near infrared chemical imaging microscopy are provided.
摘要翻译:提供使用近红外辐射显微镜的化学成像系统。 该系统包括使用近红外辐射波长的光和可见波长的光来照射样品的区域的照明源。 发送的反射的<?delete-start id =“DEL-S-00001”date =“20080101”?>,<?delete-end id =“DEL-S-00001”?> <? insert-start id =“INS-S-00001”date =“20080101”?>或<?insert-end id =“INS-S-00001”?>发出<?delete-start id =“DEL-S-00002 收集来自被照射区域的近红外波长的辐射光的“日期=”20080101“→>或分散的<?delete-end id =”DEL-S-00002“?>从其产生准直光束。 提供近红外成像光谱仪用于选择<?delete-start id =“DEL-S-00003”date =“20080101”?> a <?delete-end id =“DEL-S-00003”?>近红外辐射 准直光束的<?insert-start id =“INS-S-00002”date =“20080101”?> s <?insert-end id =“INS-S-00002”?> <?insert-start id =“INS-S-00003”date =“20080101”?>光谱仪包括液晶可调滤波器。 <?insert-end id =“INS-S-00003”?> <?delete-start id =“DEL-S-00004”date =“20080101”?> filters <?delete-end id =“DEL-S -00004“?> <?insert-start id =”INS-S-00004“date =”20080101“?>选择<?insert-end id =”INS-S-00004“?> 进一步处理。 同时检测来自样品的照射区域的可见波长的光,提供样品的同时可见和近红外化学成像分析。 提供了三维近红外化学成像显微镜的两种有效手段。
摘要:
Provided herein are methods for identifying risk of melanoma in a subject, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating melanoma, and therapeutic methods for treating melanoma in a subject. These embodiments are based upon an analysis of polymorphic variations in a BRAF nucleic acid, which has a nucleotide sequence exemplified by SEQ ID NO:1.
摘要翻译:本文提供用于鉴定受试者中黑素瘤风险的方法,用于实施该方法的试剂和试剂盒,用于鉴定治疗黑素瘤的候选治疗剂的方法,以及用于治疗受试者中黑素瘤的治疗方法。 这些实施方案基于具有SEQ ID NO:1示例的核苷酸序列的BRAF核酸中的多态性变异的分析。
摘要:
Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
摘要:
A method and a portable device for assessing the occurrence of an agent in a sample. A sample is illuminated with photons emanating from a portable device to produce photons reflected, emitted, or absorbed from a set of multiple points in the sample having a defined geometric relationship. The portable device is used to simultaneously illuminate the sample and analyze the photons reflected, emitted, or absorbed from the set of multiple points using spectroscopic methods, including infrared, fluorescence, and UV/visible. The agent assessed may include a hazardous agent, a chemical agent, a biological agent, a microorganism, a bacterium, a protozoan, a virus, and combinations thereof.