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公开(公告)号：US5716838A
公开(公告)日：1998-02-10
申请号：US487396
申请日：1995-06-07
IPC分类号： A23L1/236 , A21D2/18 , A23C9/13 , A23C9/152 , A23G3/00 , A23G3/34 , A23G3/42 , A23G3/48 , A23G4/00 , A23G4/10 , A23J3/16 , A23L1/09 , A23L1/31 , A23L1/314 , A23L1/32 , A23L2/60 , A61K8/00 , A61K8/60 , A61K8/66 , A61K8/73 , A61K9/36 , A61K31/00 , A61K31/02 , A61K38/21 , A61K47/26 , A61Q11/00 , A61Q17/04 , A61Q19/00 , C07H20060101 , C07H1/00 , C07H1/06 , C07H3/00 , C07H3/04 , C07H3/06 , C07K7/00 , C08B37/00 , C12N1/20 , C12N9/24 , C12N9/26 , C12N9/90 , C12P19/00 , C12P19/12 , C12P19/14 , C12P19/24 , C12R1/41 , C13K20060101 , C13K13/00
CPC分类号： C13K13/00 , A23G3/343 , A23G3/346 , A23G3/42 , A23G4/10 , A23L13/428 , A23L15/20 , A23L27/33 , A61K8/60 , A61K8/66 , A61Q11/00 , A61Q19/00 , C07H1/00 , C07H3/04 , C12N9/90 , C12P19/12 , A23G2200/06 , A61Q17/04 , A61Q19/02 , A61Q7/00
摘要： Disclosed are novel non-reducing saccharide-forming enzyme, and its preparation and uses. The enzyme is obtainable from the culture of microorganisms such as Rhizobium sp. M-11 (FERM BP 4130) and Arthrobacter sp. Q36 (FERM BP-4316), and capable of forming non-reducing saccharides having a trehalose structure when allowed to act-on reducing partial starch hydrolysates. Glucoamylase and .alpha.-glucosidase readily yield trehalose when allowed to act on the non-reducing saccharides. These non-reducing saccharides and trehalose are extensively useful in food products, cosmetics and pharmaceuticals.
摘要翻译： 公开了新型非还原性糖形成酶及其制备和用途。 该酶可从诸如根瘤菌属的微生物培养物获得。 M-11（FERM BP 4130）和节杆菌属 Q36（FERM BP-4316），并且能够形成具有海藻糖结构的非还原性糖，当它们用于还原部分淀粉水解产物时。 葡糖淀粉酶和α-葡萄糖苷酶当允许作用于非还原糖时容易产生海藻糖。 这些非还原性糖和海藻糖广泛用于食品，化妆品和药物。
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公开(公告)号：US5677442A
公开(公告)日：1997-10-14
申请号：US476505
申请日：1995-06-07
IPC分类号： A23G3/00 , A23G3/34 , A23G3/42 , A23G4/00 , A23G4/10 , A23L15/00 , A23L27/30 , A61K8/60 , A61K8/66 , A61Q11/00 , A61Q19/00 , C07H1/00 , C12N1/20 , C12N9/26 , C12N9/90 , C12P19/12 , C13K13/00
CPC分类号： C12N9/90 , A23G3/343 , A23G3/346 , A23G3/42 , A23G4/10 , A23L15/20 , A23L27/33 , A61K8/60 , A61K8/66 , A61Q11/00 , A61Q19/00 , C07H1/00 , C07H3/04 , C12P19/12 , C13K13/00 , A23G2200/06 , A61Q17/04 , A61Q19/02 , A61Q7/00
摘要： Disclosed are novel non-reducing saccharide-forming enzyme, and its preparation and uses. The enzyme is obtainable from the culture of microorganisms such as Rhizobium sp. M-11 (FERM BP 4130) and Arthrobacter sp. Q36 (FERM BP-4316), and capable of forming non-reducing saccharides having a trehalose structure when allowed to act on reducing partial starch hydrolysates. Glucoamylase and .alpha.-glucosidase readily yield trehalose when allowed to act on the non-reducing saccharides. These non-reducing saccharides and trehalose are extensively useful in food products, cosmetics and pharmaceuticals. Also disclosed is a method of crystallizing trehalose from a 65 to 90% aqueous solution in the absence of organic solvent.
摘要翻译： 公开了新型非还原性糖形成酶及其制备和用途。 该酶可从诸如根瘤菌属的微生物培养物获得。 M-11（FERM BP 4130）和节杆菌属 Q36（FERM BP-4316），并能够形成具有海藻糖结构的非还原性糖类，当其作用于还原部分淀粉水解产物时。 葡糖淀粉酶和α-葡萄糖苷酶当允许作用于非还原糖时容易产生海藻糖。 这些非还原性糖和海藻糖广泛用于食品，化妆品和药物。 还公开了一种在不存在有机溶剂的情况下从65％至90％的水溶液中结晶海藻糖的方法。
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73.发明授权Non-reducing oligosaccharide with neotrehalose structure, and its production and uses 失效非还原寡糖具有新海藻糖结构，其生产和用途
公开(公告)号：US5656308A
公开(公告)日：1997-08-12
申请号：US466440
申请日：1995-06-06
申请人： Hajime Aga , Takashi Shibuya , Toshiyuki Sugimoto , Toshio Miyake
发明人： Hajime Aga , Takashi Shibuya , Toshiyuki Sugimoto , Toshio Miyake
IPC分类号： A23C9/00 , A23C9/13 , A23G1/00 , A23G1/56 , A23G3/34 , A23K1/16 , A23L1/064 , A23L1/09 , A23L1/187 , A23L1/236 , A23L1/30 , A61K8/60 , A61K9/00 , A61K9/10 , A61K9/20 , A61K31/70 , A61K31/702 , A61K31/715 , A61K47/26 , A61P3/00 , A61Q7/00 , A61Q11/00 , A61Q19/00 , C07H3/06 , C08B37/00 , C12P19/04 , C12P19/16 , C12P19/18 , C13K1/06 , C13K13/00 , A23L1/00 , A61K7/42
CPC分类号： C13K13/00 , A23C9/005 , A23C9/1307 , A23G1/56 , A23G3/346 , A23K20/163 , A23L21/12 , A23L27/33 , A23L9/12 , A61K47/26 , A61K8/60 , A61K9/0014 , A61K9/0019 , A61Q19/00 , C07H3/06 , C13K1/06 , A23G2200/06 , A61Q11/00 , A61Q19/02 , A61Q7/00 , Y10S426/804
摘要： Disclosed is a novel non-reducing oligosaccharide with neotrehalose structure represented by the general formula as shown by: ##STR1## The oligosaccharide is obtainable by exposing an aqueous solution containing neotrehalose to a saccharide-transferring enzyme, and has a superior stability, reduced sweetness, appropriate viscosity, no susceptibility to crystallization and less fermentability. These features make it very useful in various compositions including foods, beverages, cosmetics and pharmaceuticals.
摘要翻译： 公开了一种新型非还原性寡糖，其具有由以下通式表示的新海藻糖结构：寡糖可通过将含有新糖海藻糖的水溶液暴露于糖转移酶而获得，并且具有优异的稳定性，降低的甜度， 适当的粘度，不易结晶和较少的发酵能力。 这些特征使其在包括食品，饮料，化妆品和药物在内的各种组合物中非常有用。
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公开(公告)号：US5627157A
公开(公告)日：1997-05-06
申请号：US348146
申请日：1994-11-28
申请人： Hiromi Hijiya , Toshio Miyake
发明人： Hiromi Hijiya , Toshio Miyake
IPC分类号： A23G3/00 , A23G3/34 , A23G3/36 , A23K1/16 , A23L1/03 , A23L1/22 , A23L1/275 , A23L1/30 , A23L1/302 , A23L3/3436 , A23L3/3544 , A24B15/30 , A61K8/00 , A61K8/60 , A61K8/67 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61P3/02 , A61P37/08 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/10 , C07H17/07 , C12N9/24 , C12P19/14 , C12P19/16 , C12P19/18 , C12P19/60
CPC分类号： A61K8/602 , A23G3/346 , A23G3/36 , A23K20/163 , A23L27/75 , A23L3/3544 , A23L33/15 , A23L5/43 , A24B15/30 , A61K8/67 , A61K8/676 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/10 , C07H17/07 , C12P19/14 , C12P19/16 , C12P19/18 , C12P19/60 , A23G2200/00 , A23G2200/04 , A23V2002/00
摘要： .alpha.-Glycosyl hesperidin, a novel hesperidin derivative wherein equimolar or more D-glucose residues are bound to hesperidin via the .alpha.-bond, is formed by a saccharide-transferring enzyme in a liquid containing hesperidin and .alpha.-glucosyl saccharide. The .alpha.-glycosyl hesperidin is easily recovered from the reaction mixture with a synthetic macroporous resin. .alpha.-Glycosyl hesperidin is superior in water-solubility, substantially tasteless and odorless, free of toxicity, and readily hydrolyzable in vivo into hesperidin and D-glucose to exhibit the physiological activity inherent to hesperidin. Thus, .alpha.-glycosyl hesperidin is favorably usable in vitamin P-enriching agents, foods, beverages, tobaccos, foods, pet foods, pharmaceuticals for susceptive diseases, cosmetics and plastics.
摘要翻译： 通过糖转移酶在含有橙皮苷和α-葡糖基糖的液体中形成α-甘氨酰橙皮苷，其中等摩尔或更多D-葡萄糖残基通过α键与橙皮苷结合的新型橙皮苷衍生物。 用合成的大孔树脂容易地从反应混合物中回收α-糖基橙皮苷。 α-糖基橙皮苷在水溶性方面优异，基本上无味无臭，无毒性，并且在体内易于水解成橙皮苷和D-葡萄糖以显示橙皮苷固有的生理活性。 因此，α-糖基橙皮苷有利地用于维生素P富集剂，食品，饮料，烟草，食品，宠物食品，用于感染性疾病的药物，化妆品和塑料。
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公开(公告)号：US5622859A
公开(公告)日：1997-04-22
申请号：US623007
申请日：1996-03-28
CPC分类号： C12R1/46 , A23K10/12 , A23K10/32 , C05F5/002 , C05F5/006 , C05F5/008 , C12P19/04 , A23Y2220/00 , A23Y2240/00 , A23Y2280/00 , Y02P20/145 , Y02P60/877 , Y10S435/822
摘要： Disclosed is an alkali-treated bagasse prepared by softening a bagasse with calcium oxide together with or without sodium hydroxide while preventing the substantial decomposition of cellulose and hemicellulose, a bagasse feed and a fermented bagasse feed prepared from the alkali-treated bagasse, and their preparations and uses as well as bacteria for fermenting the alkali-treated bagasse. These bagasse and bagasse feeds save sugar-refinery industries from the difficulties to treat bagasse deemed as an unutilized industrial waste, and livestock farming industries from the shortage of roughage, and further is extremely significant in agriculture, industries of sweetening products, feed industries and livestock product processors. A bacterium strain particularly useful for the fermentation is Enterococcus faecium FERM BP-4504.
摘要翻译： 公开了一种碱处理的甘蔗渣，其通过用氧化钙与或不与氢氧化钠一起软化甘蔗渣，同时防止纤维素和半纤维素，甘蔗渣饲料和由碱处理的甘蔗渣制备的发酵甘蔗渣饲料的基本分解及其制剂 并且使用以及细菌来发酵碱处理的甘蔗渣。 这些甘蔗渣和甘蔗渣饲料节省了炼糖工业的困难，将甘蔗渣视为未利用的工业废物，畜牧业从粗粮的缺乏，在农业，甜味产品，饲料工业和牲畜行业，尤为显着 产品处理器。 特别可用于发酵的细菌菌株是屎肠球菌FERM BP-4504。
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公开(公告)号：US4843156A
公开(公告)日：1989-06-27
申请号：US692066
申请日：1985-01-16
申请人： Toshio Miyake , Shuzo Sakai , Takashi Shibuya
发明人： Toshio Miyake , Shuzo Sakai , Takashi Shibuya
CPC分类号： C07H3/06 , C13K13/005
摘要： Oligoglucosylfructosides wherein an oligoglucosylfructoside having a polymerization degree of 2 or 3 glucose units are recovered in a high purity from a feed solution additionally containing substantial amounts of higher- and lower-oligosaccharides by sequentially admitting predetermined volumes of the feed solution and water to the column of a strongly-acidic cation exchange resin in alkaline-earth metal form; sequentially separating the effluents from the column into the first fraction rich in the higher oligosaccharide, the second fraction rich in the higher oligosaccharide but highly contaiminated with the oligoglucosylfructoside, the first fraction rich in the oligoglucosylfructoside, the fourth fraction rich in the oligoglucosylfructoside but highly contaminated with the lower oligosaccharide, and the fifth fraction rich in the lower oligosaccharide; and recovering the third fraction. The second- and fourth fractions can be admitted to the column so as to decrease the amount of elution water and also to recover the high-oligoglucosylfructoside fraction in a much higher concentration and recovery yield.
摘要翻译： 其中通过依次将预定体积的进料溶液和水顺序地加入到含有大量低聚糖的进料溶液的塔中，通过另外含有大量的高级和低级寡糖的进料溶液以高纯度从高纯度回收聚合度为2或3个葡萄糖单元的寡葡糖基果糖苷 碱土金属形式的强酸性阳离子交换树脂; 将从柱中排出的污水依次分离成富含较高寡糖的第一级分，第二级分富含高寡聚物，但与寡葡糖基果糖苷高度接触，第一级富含寡聚葡糖基果糖苷，第四级富含低聚葡糖基果糖苷但高度污染 低级寡糖，第五级富含低聚糖; 并回收第三部分。 可以将第二和第四级分进入柱，以减少洗脱水的量，并且还可以以更高的浓度和回收率获得高寡葡糖基果糖苷级分。
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公开(公告)号：US4824938A
公开(公告)日：1989-04-25
申请号：US093089
申请日：1987-08-31
申请人： Shunsaku Koyama , Toshio Miyake
发明人： Shunsaku Koyama , Toshio Miyake
IPC分类号： A61K38/16 , A61K9/00 , A61K9/08 , A61K38/00 , A61K38/21 , A61K38/22 , A61K38/27 , A61K47/36 , C07K14/485 , C07K14/505 , C07K14/525 , C07K14/555 , C07K14/59 , C07K14/61 , C07K15/00 , A61K37/02 , A61K37/24 , A61K37/48
CPC分类号： A61K9/0019 , A61K47/36 , C07K14/485 , C07K14/505 , C07K14/525 , C07K14/555 , C07K14/59 , C07K14/61
摘要： Proteinaceous bioactive substances (including lymphokine and peptide hormone) in dry solid are extremely stabilized by the presence of the specific polysaccharide mainly composed of repeating maltotriose units. Pullulan, elsinan, and their partial hydrolysates are feasible as the polysaccharide. The weight ratio of the polysaccharide to the substance which effectively stabilizes the latter substance is at least 0.5 on the basis of dry solids. The dry solid is advantageously usable as a test reagent, injection, granule, tablet, suppository or ointment.
摘要翻译： 通过主要由重复麦芽三糖单元组成的特定多糖的存在，干燥固体中的蛋白质生物活性物质（包括淋巴因子和肽激素）极度稳定。 支链淀粉，elsinan及其部分水解产物作为多糖是可行的。 基于干固体，多糖与有效稳定后者物质的物质的重量比至少为0.5。 干固体有利地用作试剂，注射剂，颗粒剂，片剂，栓剂或软膏剂。
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78.发明授权
公开(公告)号：US4816272A
公开(公告)日：1989-03-28
申请号：US133813
申请日：1987-12-16
申请人： Masakazu Mitsuhashi , Shuzo Sakai , Toshio Miyake
发明人： Masakazu Mitsuhashi , Shuzo Sakai , Toshio Miyake
CPC分类号： A23L7/109
摘要： Crystalline .alpha.-maltose extremely improves the stability, taste quality and shelf life of noodles and alimentary pastes, as well as decreases the addition of water in their preparation. Since crystalline .alpha.-maltose exerts an activity of binding flour, a satisfiable dough can be obtained with a reduced addition of water. In corporation of crystalline .alpha.-maltose into flour yields a premixed flour for preparing noodles and alimentary pastes, and the addition of water thereto attains an excellent dough products.
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79.发明授权Inclusion compound of eicosapentaenoic acid and food product containing the same 失效二十碳五烯酸的包合物和含有它们的食品
公开(公告)号：US4777162A
公开(公告)日：1988-10-11
申请号：US843645
申请日：1986-03-25
IPC分类号： A23L1/03 , A23G3/00 , A23G3/36 , A23L1/00 , A23L1/30 , A61K9/62 , A61K47/48 , C08B37/00 , C08B37/16 , A61K31/19 , A61K31/715
CPC分类号： A23G3/368 , A23L33/12 , A23P10/30 , A61K47/48969 , B82Y5/00 , C08B37/0015
摘要： A novel EPA/CD inclusion compound and a food product containing the same are disclosed. The undesirable odor of EPA is masked by including it into such EPA/CD inclusion compound. Gamma-CD is most favorable because it includes much more EPA, and highly stabilizes it. The EPA/CD inclusion compound is advantageously usable in perorally- or parenterally-usable products directed to the promotion or maintenance of health.
摘要翻译： 公开了一种新型EPA / CD包合物和含有该化合物的食品。 通过将EPA包含在这种EPA / CD包合物中来掩盖EPA的不良气味。 Gamma-CD是最有利的，因为它包含更多的EPA，并且高度稳定。 EPA / CD包合物有利地用于旨在促进或维持健康的经口或肠胃外可用的产品。
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公开(公告)号：US4623394A
公开(公告)日：1986-11-18
申请号：US719434
申请日：1985-04-03
申请人： Satoshi Nakamura , Hiromi Hijiya , Toshio Miyake
发明人： Satoshi Nakamura , Hiromi Hijiya , Toshio Miyake
摘要： A novel molded article exhibiting a gradual disintegration effect is prepared with pullulan. The effect is imparted by incorporating heteromannan into a pullulan molded article in an amount not exceeding the weight of the pullulan used. Galactomannans (e.g. guar gum, tara gum, and locust bean gum) and glucomannans (e.g. konjak mannan) are feasible as the heteromannan. The molded article is advantageously usable for industrial materials, pharmaceuticals, consumers' products, etc.
摘要翻译： 用支链淀粉制备展现出逐渐崩解效果的新型成型品。 通过将异甘露聚糖以不超过所使用的支链淀粉的重量的量引入支链淀粉模制品中来赋予该效果。 半乳甘露聚糖（例如瓜尔胶，塔拉胶和刺槐豆胶）和葡甘聚糖（例如魔芋甘露聚糖）作为异甘露聚糖是可行的。 成型品有利地用于工业材料，药品，消费者的产品等。
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