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102 条记录 (耗时 0.039 秒)

    Analyte Monitoring Device and Methods
    72.
    发明申请
    Analyte Monitoring Device and Methods 有权
    分析物监测装置及方法

    公开(公告)号：US20110257495A1

    公开(公告)日：2011-10-20

    申请号：US13087190

    申请日：2011-04-14

    申请人： Udo Hoss ,  Benjamin J. Feldman ,  Zenghe Liu ,  Hyun Cho ,  Benjamin M. Rush

    发明人： Udo Hoss ,  Benjamin J. Feldman ,  Zenghe Liu ,  Hyun Cho ,  Benjamin M. Rush

    IPC分类号： A61B5/1468

    CPC分类号： A61B5/1473 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/1468 ,  A61B5/7275 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/7455 ,  A61B2560/0252 ,  A61B2560/0443

    摘要： Method and system for determining real time analyte concentration including an analyte sensor having a portion in fluid contact with an interstitial fluid under a skin layer, an on-body electronics including a housing coupled to the analyte sensor and configured for positioning on the skin layer, the on-body electronics housing including a plurality of electrical contacts , on the housing; and a data analysis unit having a data analysis unit housing and a plurality of probes , on the housing. Each of the probes configured to electrically couple to a respective electrical contact when the data analysis unit is positioned in physical contact with the on-body electronics. The one or more signals on the probes correspond to one or more of a substantially real time monitored analyte concentration level (MACL), MACL over a predetermined time period, or a rate of change of the MACL, or combinations thereof, are provided.

    摘要翻译： 用于确定实时分析物浓度的方法和系统，包括分析物传感器，所述分析物传感器具有与皮肤层下面的间质液体流体接触的部分;体内电子器件，包括耦合到分析物传感器并被配置用于定位在皮肤层上的壳体， 在壳体上包括多个电触头的体内电子壳体; 以及数据分析单元，具有在壳体上的数据分析单元外壳和多个探针。 每个探针被配置为当数据分析单元与体内电子器件物理接触地定位时电耦合到相应的电接触。 探针上的一个或多个信号对应于基本上实时监测的分析物浓度水平（MACL），预定时间段内的MACL或MACL的变化率或其组合中的一个或多个。

    Analyte Sensors and Methods of Use
    76.
    发明申请
    Analyte Sensors and Methods of Use 有权
    分析物传感器和使用方法

    公开(公告)号：US20090292188A1

    公开(公告)日：2009-11-26

    申请号：US12533742

    申请日：2009-07-31

    申请人： Udo Hoss ,  Zenghe Liu ,  Benjamin J. Feldman

    发明人： Udo Hoss ,  Zenghe Liu ,  Benjamin J. Feldman

    IPC分类号： A61B5/1473

    CPC分类号： A61B5/1477 ,  A61B5/0002 ,  A61B5/0008 ,  A61B5/01 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/6843 ,  A61B2560/0276 ,  G01N27/327 ,  G01N27/4035

    摘要： An analyte sensor system including a substrate, a first electrode disposed on a first surface of the substrate, a second electrode disposed on a second surface of the substrate, a third electrode provided in electrical contact with at least one of the first or second electrodes, where at least a portion of the first electrode and the second electrode are subcutaneously positioned in a patient, and where the third electrode is substantially entirely positioned external to the patient, and corresponding methods are provided.

    摘要翻译： 一种分析物传感器系统，包括衬底，设置在衬底的第一表面上的第一电极，设置在衬底的第二表面上的第二电极，与第一或第二电极中的至少一个电接触地设置的第三电极， 其中第一电极和第二电极的至少一部分皮下定位在患者体内，并且其中第三电极基本上完全位于患者外部，并且提供相应的方法。

    Device for determining a glucose concentration in a tissue fluid
    77.
    发明授权
    Device for determining a glucose concentration in a tissue fluid 失效
    用于测定组织液中葡萄糖浓度的装置

    公开(公告)号：US07169600B2

    公开(公告)日：2007-01-30

    申请号：US10782290

    申请日：2004-02-19

    申请人： Udo Hoss ,  Hans-Joerg Pfleiderer ,  Ralf Gessler ,  Hans-Ulrich Zieten ,  Rolf Fussgaenger

    发明人： Udo Hoss ,  Hans-Joerg Pfleiderer ,  Ralf Gessler ,  Hans-Ulrich Zieten ,  Rolf Fussgaenger

    IPC分类号： C12M1/34

    CPC分类号： A61B5/14865 ,  A61B5/14528 ,  A61B5/14532

    摘要： The invention concerns an arrangement for determining the concentration of glucose in a tissue fluid. In the microdialysis technology used for this purpose, perfusate-containing glucose is transported in intermittent delivery pulses through a microdialysis probe inserted into the tissue fluid and dialysate obtained in this process is passed to a measuring cell to record the glucose content. In order to achieve an exact determination of glucose even with a reduced dialysis period, it is proposed that the starting content of glucose in the perfusate is adapted to the glucose content of the tissue fluid by means of a control device in accordance with a command variable derived from the measurement signals of the measuring cell. When the control deviation is negligible the momentary starting content of glucose in the perfusate can be determined as a measure for the glucose content of the tissue fluid.

    摘要翻译： 本发明涉及一种用于确定组织液中葡萄糖浓度的装置。 在用于此目的的微透析技术中，含有灌注液的葡萄糖通过插入组织液中的微量透析探针在间歇递送脉冲中运输，并将在该过程中获得的透析液送至测量池以记录葡萄糖含量。 为了即使在透析时间缩短的情况下也可以精确测定葡萄糖，建议根据命令变量，通过控制装置使灌注液中的葡萄糖的起始含量适应于组织液的葡萄糖含量 源自测量单元的测量信号。 当控制偏差可忽略时，灌注液中葡萄糖的瞬时起始含量可以被确定为组织液的葡萄糖含量的量度。

    Method for determining the concentration of glucose in a body fluid with glucose-containing perfusate
    78.
    发明授权
    Method for determining the concentration of glucose in a body fluid with glucose-containing perfusate 失效
    用含葡萄糖的灌注液测定体液中葡萄糖浓度的方法

    公开(公告)号：US06852500B1

    公开(公告)日：2005-02-08

    申请号：US09620038

    申请日：2000-07-20

    申请人： Udo Hoss ,  Hans-Joerg Pfleiderer ,  Ralf Gessler ,  Hans-Ulrich Zieten ,  Rolf Fussgaenger

    发明人： Udo Hoss ,  Hans-Joerg Pfleiderer ,  Ralf Gessler ,  Hans-Ulrich Zieten ,  Rolf Fussgaenger

    IPC分类号： G01N33/66 ,  A61B5/00 ,  G01N33/487 ,  C12Q1/54

    CPC分类号： A61B5/14865 ,  A61B5/14528 ,  A61B5/14532

    摘要： The invention concerns a method and an arrangement for determining the concentration of glucose in a body fluid. In the microdialysis technology used for this purpose, perfusate containing glucose is transported in intermittent delivery pulses through a microdialysis probe (10) inserted into the body fluid and dialysate obtained in this process is passed to a measuring cell (16) to record the glucose content. In order to achieve an exact determination of glucose even with a reduced dialysis period, it is proposed that the starting content of glucose in the perfusate is adapted to the glucose content of the body fluid by means of a control device (18, 20) in accordance with a command variable derived from the measurement signals of the measuring cell (16). When the control deviation is negligible the momentary starting content of glucose in the perfusate can be determined as a measure for the glucose content of the body fluid.

    摘要翻译： 本发明涉及一种用于确定体液中葡萄糖浓度的方法和装置。 在用于此目的的微透析技术中，含有葡萄糖的灌注液通过插入到体液中的微量透析探针（10）以间歇递送脉冲的形式输送，并将在该过程中获得的透析液送至测量池（16）以记录葡萄糖含量 。 为了即使在透析时间缩短的情况下也能够精确地确定葡萄糖，建议通过控制装置（18,20）将灌注液中葡萄糖的起始含量与体液的葡萄糖含量相适应 根据从测量单元（16）的测量信号导出的命令变量。 当控制偏差可忽略时，可以将灌注液中葡萄糖的瞬时起始含量确定为体液葡萄糖含量的量度。