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    Material for Treatment of Cerebral Infarction
    76.
    发明申请
    Material for Treatment of Cerebral Infarction 审中-公开
    用于治疗脑梗死的材料

    公开(公告)号：US20160166615A1

    公开(公告)日：2016-06-16

    申请号：US15050106

    申请日：2016-02-22

    申请人： National Center for Geriatrics and Gerontology

    发明人： Misako Nakashima ,  Masahiko Sugiyama

    IPC分类号： A61K35/32

    CPC分类号： A61K35/32 ,  A61L27/3834 ,  A61L27/3878

    摘要： A material for treatment of cerebral infarction ameliorates angiopathy at a cerebral infarction region and improves brain function. The material for treatment of cerebral infarction according to the present invention comprises a dental pulp stem cell including at least one of a CD105-positive cell, an SP cell, a CD24-positive cell, a CD271-positive cell, and a CD150-positive cell. The material for treatment of cerebral infarction according to the present invention may contain a secretory protein of the dental pulp stem cell. Transplanted dental pulp stem cells do not directly differentiate into neural progenitor cells or neural cells and indirectly participate in the promotion of differentiation to restore and cure a cerebral infarction region such that the region becomes normal.

    摘要翻译： 用于治疗脑梗塞的材料可改善脑梗死区域的血管病变，改善脑功能。 根据本发明的用于治疗脑梗死的材料包括牙髓干细胞，其包括CD105阳性细胞，SP细胞，CD24阳性细胞，CD271阳性细胞和CD150阳性中的至少一种 细胞。 根据本发明的用于治疗脑梗死的材料可以含有牙髓干细胞的分泌蛋白质。 移植的牙髓干细胞不直接分化为神经祖细胞或神经细胞，并间接参与促进分化以恢复和治愈脑梗死区域，使得该区域变得正常。

    Method for making nerve graft
    77.
    发明授权
    Method for making nerve graft 有权
    神经移植方法

    公开(公告)号：US09309494B2

    公开(公告)日：2016-04-12

    申请号：US12981581

    申请日：2010-12-30

    申请人： Li Fan ,  Chen Feng ,  Wen-Mei Zhao

    发明人： Li Fan ,  Chen Feng ,  Wen-Mei Zhao

    IPC分类号： C12N5/079 ,  C12N5/0793 ,  A61L27/34 ,  A61L27/38

    CPC分类号： C12N5/0619 ,  A61L27/34 ,  A61L27/383 ,  A61L27/3878 ,  A61L2400/12 ,  A61L2430/32 ,  C12N2533/20 ,  C12N2533/32 ,  C12N2533/50 ,  C12N2535/00 ,  C08L89/00

    摘要： A method for making a nerve graft includes the following steps. A culture layer including a carbon nanotube film structure and a protein layer is provided. The protein layer is located on a surface of the carbon nanotube film structure. A number of nerve cells are seeded on a surface of the protein layer away from the carbon nanotube film structure. The nerve cells are cultured until a number of neurites branch from the nerve cells and are connected between the nerve cells.

    摘要翻译： 制造神经移植物的方法包括以下步骤。 提供了包括碳纳米管膜结构和蛋白质层的培养层。 蛋白质层位于碳纳米管膜结构的表面上。 将多个神经细胞接种在远离碳纳米管膜结构的蛋白质层的表面上。 将神经细胞培养直到许多神经突从神经细胞分支并连接在神经细胞之间。

    DEVICES AND METHODS FOR THE PREVENTION AND TREATMENT OF NEUROMAS
    78.
    发明申请
    DEVICES AND METHODS FOR THE PREVENTION AND TREATMENT OF NEUROMAS 有权
    用于预防和治疗神经瘤的装置和方法

    公开(公告)号：US20150374887A1

    公开(公告)日：2015-12-31

    申请号：US14768826

    申请日：2014-02-18

    申请人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

    发明人： Mario I. ROMERO-ORTEGA ,  Rafael GRANJA-VAZQUEZ

    IPC分类号： A61L31/16 ,  A61B17/11 ,  A61L31/04

    CPC分类号： A61L31/16 ,  A61B17/1128 ,  A61B17/12 ,  A61B2017/00893 ,  A61L27/3878 ,  A61L31/041 ,  A61L2300/432

    摘要： In one aspect, nerve growth inhibition devices are described herein. In some embodiments, a nerve growth inhibition device described herein comprises a tube having a proximal end and a distal end. A matrix material is disposed in the tube, and the matrix material comprises one or more microchannels. The proximal end of the tube comprises an opening operable to receive nerve tissue, the distal end of the tube is sealed, and the microchannels of the matrix material extend from the proximal end of the tube toward the distal end of the tube.

    摘要翻译： 在一个方面，本文描述了神经生长抑制装置。 在一些实施方案中，本文所述的神经生长抑制装置包括具有近端和远端的管。 基质材料设置在管中，基体材料包括一个或多个微通道。 管的近端包括可操作以接收神经组织的开口，管的远端被密封，并且基质材料的微通道从管的近端延伸到管的远端。