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83 条记录 (耗时 0.061 秒)

    Peptide sequences and compositions
    74.
    发明授权
    Peptide sequences and compositions 有权
    肽序列和组成

    公开(公告)号：US08475802B2

    公开(公告)日：2013-07-02

    申请号：US12278728

    申请日：2007-02-05

    申请人： Gregory Alan Stoloff ,  Wilson Romero Caparros-Wanderley

    发明人： Gregory Alan Stoloff ,  Wilson Romero Caparros-Wanderley

    IPC分类号： A61K39/00 ,  A61K39/12 ,  A61K38/00 ,  C07K14/00

    CPC分类号： A61K39/145 ,  A61K39/12 ,  A61K2039/55566 ,  A61K2039/57 ,  A61K2039/572 ,  A61K2039/70 ,  C07K7/08 ,  C07K14/005 ,  C07K14/11 ,  C12N2760/16122 ,  C12N2760/16134 ,  C12N2760/16171 ,  C12N2760/16222 ,  C12N2760/16234 ,  C12N2760/16271

    摘要： Provided is a polypeptide having no more than 100 amino acids, which polypeptide has one or more sequences having at least 60% homology with any of SEQ ID 1-6, or has two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-6 that has the same length as the epitope: SEQ ID 1DLEALMEWLKTRPILSPLTKGILGFVFTLTVP SEQ ID 2LLYCLMVMYLNPGNYSMQVKLGTLCALCEKQASHS SEQ ID 3DLIFLARSALILRGSVAHKSC SEQ ID 4PGIADIEDLTLLARSMVVVRP SEQ ID 5LLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQ SEQ ID 6IIGILHLILWILDRLFFKCIYRLF wherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete influenza virus protein.

    摘要翻译： 提供的多肽具有不超过100个氨基酸，该多肽具有与SEQ ID 1-6中任一个具有至少60％同源性的一个或多个序列，或具有两个或多个具有7个氨基酸或更多个表位的表位，每个表位具有 与SEQ ID 1-6中任一个具有与表位相同长度的亚序列至少60％的同源性：SEQ ID 1 DLEALMEWLKTRPILSPLTKGILGFVFTLTVP SEQ ID 2 LLYCLMVMYLNPGNYSMQVKLGTLCALCEKQASHS SEQ ID 3 DLIFLARSALILRGSVAHKSC SEQ ID 4 PGIADIEDLTLLARSMVVVRP SEQ ID 5 LLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQ SEQ ID 6 IIGILHLILWILDRLFFKCIYRLF其中，所述多肽在表达主要组织相容性复合体（MHC）等位基因的脊椎动物中是免疫原性的，并且其中所述多肽不是完整的流感病毒蛋白质。

    Peptide Sequences and Compositions
    78.
    发明申请
    Peptide Sequences and Compositions 有权
    肽序列和组合物

    公开(公告)号：US20120219575A1

    公开(公告)日：2012-08-30

    申请号：US13465940

    申请日：2012-05-07

    申请人： Gregory Alan Stoloff ,  Wilson Romero Capparros-Wanderley

    发明人： Gregory Alan Stoloff ,  Wilson Romero Capparros-Wanderley

    IPC分类号： A61K39/145 ,  C07K14/11 ,  A61P37/02 ,  C07K14/00

    CPC分类号： A61K39/145 ,  A61K39/12 ,  A61K2039/55566 ,  A61K2039/57 ,  A61K2039/572 ,  A61K2039/70 ,  C07K7/08 ,  C07K14/005 ,  C07K14/11 ,  C12N2760/16122 ,  C12N2760/16134 ,  C12N2760/16171 ,  C12N2760/16222 ,  C12N2760/16234 ,  C12N2760/16271

    摘要： Provided is a polypeptide having no more than 100 amino acids, which polypeptide comprises one or more sequences having at least 60% homology with any of SEQ ID 1-6, or comprises two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-6 that has the same length as the epitope: SEQ ID 1 DLEALMEWLKTRPILSPLTKGILGFVFTLTVP SEQ ID 2 LLYCLMVMYLNPGNYSMQVKLGTLCALCEKQASHS SEQ ID 3 DLIFLARSALILRGSVAHKSC SEQ ID 4 PGIADIEDLTLLARSMVVVRP SEQ ID 5 LLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQ SEQ ID 6 IIGILHLILWILDRLFFKCIYRLF wherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete influenza virus protein.

    摘要翻译： 提供的多肽具有不超过100个氨基酸，该多肽包含与SEQ ID 1-6中任一个具有至少60％同源性的一个或多个序列，或包含具有7个或更多个氨基酸的两个或多个表位，每个表位具有 与SEQ ID 1-6中任一个具有与表位相同长度的亚序列至少60％的同源性：SEQ ID 1 DLEALMEWLKTRPILSPLTKGILGFVFTLTVP SEQ ID 2 LLYCLMVMYLNPGNYSMQVKLGTLCALCEKQASHS SEQ ID 3 DLIFLARSALILRGSVAHKSC SEQ ID 4 PGIADIEDLTLLARSMVVVRP SEQ ID 5 LLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQ SEQ ID 6 IIGILHLILWILDRLFFKCIYRLF其中，所述多肽在表达主要组织相容性复合体（MHC）等位基因的脊椎动物中是免疫原性的，并且其中所述多肽不是完整的流感病毒蛋白质。