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公开(公告)号：US4298570A
公开(公告)日：1981-11-03
申请号：US141455
申请日：1980-04-18
申请人： John E. Lillig , Richard C. Meyer
发明人： John E. Lillig , Richard C. Meyer
CPC分类号： G01N35/1083 , B01L9/06 , G01N21/253 , G01N2035/00455 , G01N2035/00534 , G01N35/1004
摘要： A containment apparatus for liquids. The device may be used with nephelometric instruments to contain sample liquids for serial dilution. The containment apparatus includes a tray section having a plurality of wells formed as an integral part of the tray section. The wells include well portions extending from the tray section such that the well portions are insertible into holes in the turntable rim to secure the tray section to the rim.
摘要翻译： 液体容纳装置。 该装置可与比浊法仪器一起使用以包含用于连续稀释的样品液体。 容纳装置包括具有形成为托盘部分的一体部分的多个孔的托盘部分。 井包括从托盘部分延伸的井部分，使得井口部分可插入转盘轮缘中的孔中，以将托盘部分固定到轮辋上。
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公开(公告)号：US10168344B2
公开(公告)日：2019-01-01
申请号：US13334619
申请日：2011-12-22
摘要： A storage and retrieval system is provided. The storage and retrieval system having a frame and a shuttle movable within the frame, the shuttle having a carriage extending at least partially between a top and bottom of the frame. At least one tension member extends between a first and second ends of the frame and is coupled to the shuttle. At least one drive member extends between the first and second ends of the frame and is coupled to the shuttle. The at least one drive member and the at least one tension member project from opposite sides of the shuttle towards respective first and second ends of the frame and effect stabilization of the carriage against at least rotation relative to the frame. The at least one tension member crosses the at least one drive member and the at least one drive member effects movement of the shuttle.
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公开(公告)号：US20120321419A1
公开(公告)日：2012-12-20
申请号：US13595817
申请日：2012-08-27
IPC分类号： B65G1/137
CPC分类号： G01N35/0099 , G01N35/00732 , G01N2035/00752 , Y10T436/11 , Y10T436/113332 , Y10T436/114165
摘要： An automated storage system for storing large quantities of samples in trays includes a storage compartment, a tray shuttle compartment abutting the storage compartment on one side and a plurality of independent modules on the other side. The modules perform processing of samples that are retrieved from the storage compartment by a tray shuttle, including extraction of selected samples from retrieved source trays and transfer of the selected samples into a separate, destination tray that can be further processed or removed from the system for use. The independent operation of the modules permits handling and processing to be performed simultaneously by different modules while the tray shuttle accesses additional samples within the storage compartment. In one embodiment, a vertical carousel is used to vertically align a desired tray with the tray shuttle, while the tray shuttle operates within a horizontal plane.
摘要翻译： 用于将大量样品储存在托盘中的自动存储系统包括储存室，在一侧邻接储藏室的托盘穿梭隔室和另一侧上的多个独立模块。 模块执行通过托盘穿梭从储存室取出的样品的处理，包括从检索的源托盘提取所选样品并将所选样品转移到单独的目的地托盘中，所述目的托盘可以进一步处理或从系统中移除 使用。 模块的独立操作允许不同模块同时执行处理和处理，而托盘穿梭器访问存储隔间内的附加样品。 在一个实施例中，垂直转盘用于将期望的托盘垂直地对准托盘梭，而托盘梭在水平面内运行。
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公开(公告)号：US08252232B2
公开(公告)日：2012-08-28
申请号：US11626359
申请日：2007-01-23
CPC分类号： G01N35/0099 , G01N35/00732 , G01N2035/00752 , Y10T436/11 , Y10T436/113332 , Y10T436/114165
摘要： An automated storage system for storing large quantities of samples in trays includes a storage compartment, a tray shuttle compartment abutting the storage compartment on one side and a plurality of independent modules on the other side. The modules perform processing of samples that are retrieved from the storage compartment by a tray shuttle, including extraction of selected samples from retrieved source trays and transfer of the selected samples into a separate, destination tray that can be further processed or removed from the system for use. The independent operation of the modules permits handling and processing to be performed simultaneously by different modules while the tray shuttle accesses additional samples within the storage compartment. In one embodiment, a vertical carousel is used to vertically align a desired tray with the tray shuttle, while the tray shuttle operates within a horizontal plane.
摘要翻译： 用于将大量样品储存在托盘中的自动存储系统包括储存室，在一侧邻接储藏室的托盘穿梭隔室和另一侧上的多个独立模块。 模块执行通过托盘穿梭从储存室取出的样品的处理，包括从检索的源托盘提取所选样品并将所选样品转移到单独的目的地托盘中，所述目的托盘可以进一步处理或从系统中移除 使用。 模块的独立操作允许不同模块同时执行处理和处理，而托盘穿梭器访问存储隔间内的附加样品。 在一个实施例中，垂直转盘用于将期望的托盘垂直地对准托盘梭，而托盘梭在水平面内运行。
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公开(公告)号：US20120163945A1
公开(公告)日：2012-06-28
申请号：US13334619
申请日：2011-12-22
IPC分类号： B65G1/06
CPC分类号： G01N35/0099 , G01N35/00732 , G01N2035/00752 , Y10T436/11 , Y10T436/113332 , Y10T436/114165
摘要： A storage and retrieval system is provided. The storage and retrieval system having a frame and a shuttle movable within the frame, the shuttle having a carriage extending at least partially between a top and bottom of the frame. At least one tension member extends between a first and second ends of the frame and is coupled to the shuttle. At least one drive member extends between the first and second ends of the frame and is coupled to the shuttle. The at least one drive member and the at least one tension member project from opposite sides of the shuttle towards respective first and second ends of the frame and effect stabilization of the carriage against at least rotation relative to the frame. The at least one tension member crosses the at least one drive member and the at least one drive member effects movement of the shuttle.
摘要翻译： 提供存储和检索系统。 存储和取回系统具有框架和可在框架内移动的梭子，梭子具有至少部分地在框架的顶部和底部之间延伸的托架。 至少一个张紧构件在框架的第一和第二端之间延伸并且联接到梭子。 至少一个驱动构件在框架的第一和第二端之间延伸并且联接到梭子。 所述至少一个驱动构件和所述至少一个张紧构件从所述梭子的相对侧朝向所述框架的相应的第一和第二端突出，并且相对于所述框架至少使所述托架抵抗至少旋转。 所述至少一个张紧构件穿过所述至少一个驱动构件，并且所述至少一个驱动构件影响所述梭的运动。
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公开(公告)号：USD480815S1
公开(公告)日：2003-10-14
申请号：US29165712
申请日：2002-08-13
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公开(公告)号：US06329139B1
公开(公告)日：2001-12-11
申请号：US08912998
申请日：1997-08-11
申请人： Michael P. Nova , John E. Lillig , Kanchana Sanjaya Gunesekera Karunaratne , William Ewing , Yozo Satoda , Hanan Potash
发明人： Michael P. Nova , John E. Lillig , Kanchana Sanjaya Gunesekera Karunaratne , William Ewing , Yozo Satoda , Hanan Potash
IPC分类号： C12Q168
CPC分类号： G11C13/0019 , B01J19/0046 , B01J2219/00283 , B01J2219/00295 , B01J2219/00299 , B01J2219/00308 , B01J2219/0031 , B01J2219/00313 , B01J2219/00319 , B01J2219/00333 , B01J2219/00344 , B01J2219/00454 , B01J2219/00461 , B01J2219/00463 , B01J2219/005 , B01J2219/00502 , B01J2219/0054 , B01J2219/00542 , B01J2219/00547 , B01J2219/00549 , B01J2219/00551 , B01J2219/00554 , B01J2219/0056 , B01J2219/00563 , B01J2219/00567 , B01J2219/00569 , B01J2219/00585 , B01J2219/0059 , B01J2219/00592 , B01J2219/00596 , B01J2219/00689 , B01J2219/00691 , B01J2219/00695 , B01J2219/0072 , B01J2219/00722 , B01J2219/00725 , B01L3/50255 , B01L3/50825 , B01L3/5453 , B01L2300/022 , B01L2300/0609 , B01L2400/0655 , B82Y10/00 , C07H21/00 , C07K1/00 , C07K1/04 , C07K1/047 , C08J7/16 , C08J2327/12 , C40B40/06 , C40B40/10 , C40B50/14 , C40B60/14 , C40B70/00 , G01N33/542 , G01N33/54353 , G01N33/54393 , G01N35/00732 , G01N35/00871 , G01N2015/149 , G01N2035/00782 , G01N2333/9121 , G01N2500/00 , G11C13/0014 , G11C13/025 , G11C2213/81
摘要： Automated drug discovery protocols, or partially automated protocols, in which matrices with memories serve as the platform on which all manipulations are performed or serve as the repository of information that is transferred to other memories as the synthesized compounds are processed and screened. Also provided are automated drug discovery units for use in the protocols. The units provide a means for seamless data tracking and include instrumentation and vials with memories for information transfer to other memories in a unit. The units, which are provided herein, include some or all of the following: an automated or manual sorter, microvessels, which contain memories, an automated or semi-automated synthesizer, a microvessel washer/dryer, a manual or automated cleaver for removing compounds from the matrix with memory microvessels, and associated software. The memories may be any of any type, including electromagnetically encodable memories and optical memories, or combinations thereof. The memories may be pre-encoded or may be encodabie during, after or before processing. Also provided are manual and automated methods for sorting matrices with memories.
摘要翻译： 自动药物发现协议或部分自动化协议，其中具有记忆的矩阵作为执行所有操作的平台，或者当作为合成化合物被处理和筛选时被传送到其他存储器的信息库。 还提供了用于协议的自动化药物发现单元。 这些单元为无缝数据跟踪提供了一种手段，其中包括仪器和样品瓶，用于将信息传输到单元中的其他存储器。 这里提供的单元包括以下部分或全部：自动或手动分拣机，包含记忆的微血管，自动或半自动合成器，微血清洗涤器/干燥器，用于去除化合物的手动或自动切割器 从具有记忆微血管的矩阵和相关联的软件。 存储器可以是任何类型的存储器，包括电磁编码存储器和光存储器，或其组合。 存储器可以被预编码，或者可以在处理期间，之后或之前编码。 还提供了用于使用存储器排序矩阵的手动和自动化方法。
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8.发明授权
公开(公告)号：US4322216A
公开(公告)日：1982-03-30
申请号：US238306
申请日：1981-02-26
申请人： John E. Lillig , Robert K. Neeper , Paul J. Ashton
发明人： John E. Lillig , Robert K. Neeper , Paul J. Ashton
CPC分类号： G01N35/1011 , G01N2035/00534 , G01N2035/0444 , G01N2035/0451 , G01N2035/1076 , G01N35/1004 , G01N35/1083 , Y10T436/113332
摘要： A method and apparatus for conveying liquids to and from a reaction cell in an automated sample handling apparatus. The conveyance apparatus includes a track and car system. A method and apparatus is disclosed which precisely positions the cars on the track. This positioning method and apparatus includes a plurality of apertures and spaces on the track of a size and spacing to allow the cars to accurately position themselves.
摘要翻译： 一种用于在自动化样品处理装置中将液体输送到反应池的方法和装置。 输送装置包括轨道和汽车系统。 公开了一种将车辆精确地定位在轨道上的方法和装置。 该定位方法和装置包括在轨道上的多个孔和空间，其尺寸和间距允许轿厢准确地自己定位。
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9.发明授权Measuring system incorporating self-testing probe circuit and method for checking signal levels at test points within the system 失效包含自检探针电路的测量系统和用于检查系统内测试点信号电平的方法
公开(公告)号：US4270178A
公开(公告)日：1981-05-26
申请号：US94267
申请日：1979-11-14
申请人： John E. Lillig
发明人： John E. Lillig
CPC分类号： G01R31/2834 , G01R31/00
摘要： In a system which measures a parameter of a sample and displays information relating thereto, a circuit including the component elements of the system for testing signal levels at test points within the system and for displaying the test signal levels. Switching means places the system in either a transducing mode for measuring the parameter or in a combined transducing/self-testing mode for simultaneous testing during transducing operation. The testing circuit includes an operator manipulated probe for contacting any of the test points and an analog multiplexer input of the system for multiplexing the probe test signal and the transducing signal. The multiplexed signals are converted to digital form and processed by the system's computer for display. In the combined transducing/self-testing mode, the probe test signal information is outputted to the system display while the transducing output thereto is inhibited. The transducing output information derived during testing is processed and stored by the computer for subsequent display.
摘要翻译： 在测量样本的参数并显示与其相关的信息的系统中，包括用于测试系统内的测试点处的信号电平并用于显示测试信号电平的系统的组成元件的电路。 切换装置将系统置于用于测量参数的转换模式中，或者在组合式转换/自检模式下进行转换操作期间的同时测试。 测试电路包括用于接触任何测试点的操作者操纵探针和用于多路复用探针测试信号和转换信号的系统的模拟多路复用器输入。 复用的信号被转换为数字形式，并由系统的计算机进行处理以进行显示。 在组合式转换/自检模式中，将探头测试信号信息输出到系统显示器，同时抑制其转换输出。 在测试期间导出的转换输出信息由计算机处理和存储以供后续显示。
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公开(公告)号：US4007105A
公开(公告)日：1977-02-08
申请号：US595207
申请日：1975-07-11
申请人： Edmund E. Buzza , John E. Lillig
发明人： Edmund E. Buzza , John E. Lillig
CPC分类号： G01N31/164 , G01N27/44
摘要： Titration apparatus for measuring chloride electrolyte in blood samples including a pair of coulometric generator electrodes for titrating the chloride with silver ions to precipitate silver chloride and a pair of amperometric detector electrodes for detecting completion of the silver chloride precipitation. The amperometric electrodes and one of the coulometric electrodes (cathode) are contained in a unitary electrode module which is mounted separately from the remaining coulometric electrode (anode) and which is readily removable for cleaning.
摘要翻译： 用于测量血液样品中的氯化物电解质的滴定装置，包括一对用银离子滴定氯化物以沉淀氯化银的电量发生器电极，以及一对电流检测器电极，用于检测氯化银沉淀的完成。 电流电极和库仑电极（阴极）中的一个包含在与剩余的库仑电极（阳极）分开安装并且易于移除以进行清洁的单一电极模块中。
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