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1.发明授权公开(公告)号：US11045300B2
公开(公告)日：2021-06-29
申请号：US15943036
申请日：2018-04-02
IPC分类号： A61M1/36 , A61F2/06 , A61B17/12 , A61B5/0215 , A61B5/00 , A61B5/027 , A61B5/01 , A61B5/107 , A61F7/12 , A61B17/11 , A61M25/10 , A61B17/00 , A61M27/00 , A61F7/00 , A61B18/02
摘要： Systems, devices, and methods for organ Retroperfusion along with regional mild hypothermia. One such system includes a hypothermia system including a hypothermia system outlet and a hypothermia system inlet; and a connector comprising a coolant inlet, a coolant outlet, a coolant reservoir, and a blood lumen, whereby the coolant inlet is configured to couple to the hypothermia system outlet and whereby the coolant outlet is configured to couple to the hypothermia system inlet; whereby a cooling product, when the hypothermia system is connected to the connector, can flow from the hypothermia system, through the hypothermia system outlet, into the coolant inlet, through the coolant reservoir, into the coolant outlet, and into the hypothermia system inlet, so that the cooling product can cool blood flowing through the blood lumen.
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2.发明授权公开(公告)号：US09675458B2
公开(公告)日：2017-06-13
申请号：US13965548
申请日：2013-08-13
CPC分类号： A61F2/2493 , A61B17/12036 , A61B17/1204 , A61B17/12109 , A61F2/06 , A61F2/07 , A61F7/12 , A61F2007/0056 , A61F2210/0004 , A61F2250/0003 , A61M1/3613 , A61M25/0075 , A61M25/04 , A61M2025/1052 , A61M2025/1095
摘要： Methods and devices for controlling blood perfusion pressure along with regional mild hypothermia. In at least one embodiment of a device for controlling blood perfusion pressure within a vessel of the present disclosure, the device comprises an elongated body having a lumen, a proximal end configured for placement in a first area having a first blood pressure, and a distal end configured for placement in a second area having a second blood pressure, a partial occluder positioned within the lumen of the elongated body between the proximal end and the distal end, the partial occluder configured so not to fully occlude a blood vessel and to equalize the first blood pressure at the first area with the second blood pressure at the second area, and a regional hypothermia system operably coupled thereto, the regional hypothermia system operable to reduce and/or regulate a temperature of a bodily fluid flowing therethrough.
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公开(公告)号：US09504781B2
公开(公告)日：2016-11-29
申请号：US14093300
申请日：2013-11-29
IPC分类号： A61M1/36 , A61B5/0215 , A61F2/06 , A61B17/12 , A61M27/00 , A61B17/00 , A61B17/11 , A61M25/10
CPC分类号： A61F2/06 , A61B5/02152 , A61B17/11 , A61B17/12036 , A61B17/1204 , A61B17/12109 , A61B17/12136 , A61B17/1214 , A61B2017/00026 , A61B2017/00199 , A61B2017/00212 , A61B2017/00221 , A61B2017/00252 , A61B2017/1107 , A61B2017/1135 , A61B2017/1205 , A61F2002/065 , A61M1/3653 , A61M1/3655 , A61M1/3659 , A61M27/00 , A61M2025/1052 , A61M2025/1097 , A61M2205/3523 , A61M2205/3561
摘要： Peripheral arterialization devices and methods of using the same. In an exemplary embodiment of a catheter for facilitating venous arterialization of the present disclosure, the catheter comprises an elongated body extending from a proximal end to a distal end and having a lumen defined therethrough along a longitudinal length of the elongated body, the elongated body configured to attach to a graft at or near the proximal end of the elongated body and further configured to permit fluid to flow through the graft, through the lumen, and out of one or more apertures defined within the elongated body at or near the distal end to facilitate venous arterialization upon at least partial implantation of the catheter into a vein of a patient.
摘要翻译： 外周动脉化装置及其使用方法。 在用于促进本公开的静脉动脉化的导管的示例性实施例中，导管包括从近端延伸到远端的细长体，并且具有沿着细长体的纵向长度限定穿过的内腔，细长体构造 以在细长体的近端处或附近附接到移植物，并进一步构造成允许流体通过内腔流过移植物，并且从远端处或附近限定在细长体内的一个或多个孔中， 在将导管至少部分植入患者的静脉中时促进静脉动脉化。
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公开(公告)号：US09198706B2
公开(公告)日：2015-12-01
申请号：US13470452
申请日：2012-05-14
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00267 , A61B2018/00285 , A61B2018/00375 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262 , A61B2090/3966
摘要： Systems and methods for cryoablation of a tissue. In at least one embodiment of a cryoablation system of the present disclosure, the cryoablation system comprises an expandable stent comprising a proximal end and a distal end, a sidewall defining a lumen extending between the proximal end and the distal end, and a cryoablation chamber at the distal end, the expandable stent configured to permit blood flow therethrough, and a cryoablation device comprising at least one coolant tube at least partially positioned within the cryoablation chamber, wherein the at least one coolant tube is operable to produce a cryogenic environment sufficient to ablate at least a portion of a tissue engaged within the cryoablation chamber.
摘要翻译： 用于组织冷冻消融的系统和方法。 在本公开的冷冻消融系统的至少一个实施例中，冷冻消融系统包括可扩张支架，其包括近端和远端，限定在近端和远端之间延伸的内腔的侧壁，以及冷冻消融腔 所述远端，所述可扩张支架构造成允许血液流过其中;以及冷冻消融装置，其包括至少部分地定位在所述冷冻消融室内的至少一个冷却剂管，其中所述至少一个冷却剂管可操作以产生足以消融的低温环境 至少部分组织接合在冷冻消融室内。
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公开(公告)号：US09089391B2
公开(公告)日：2015-07-28
申请号：US12861251
申请日：2010-08-23
IPC分类号： A61F5/00 , A61B17/122
CPC分类号： A61F5/0013 , A61B17/122 , A61B17/1227 , A61F5/0086
摘要： Tissue restoration devices, systems, and methods. In at least one embodiment, an implantable restraining device of the present disclosure comprises a first engaging component and a second engaging component, each component configured for laparoscopic insertion into a body cavity, a first swivel arm defining a first bend and a second swivel arm defining a second bend, the first swivel arm coupled to the first engaging component at a first pivot point and coupled to the second engaging component at a second pivot point, and the second swivel arm coupled to the first engaging component at a third pivot point and coupled to the second engaging component at a fourth pivot point, and a first interconnection arm and a second interconnection arm, the first interconnection arm connected to the first swivel arm relative to the first bend, and the second interconnection arm connected to the second swivel arm relative to the second bend.
摘要翻译： 组织修复装置，系统和方法。 在至少一个实施例中，本公开的可植入约束装置包括第一接合部件和第二接合部件，每个部件被构造用于腹腔镜插入体腔中，第一旋转臂限定第一弯曲部和第二旋转臂，所述第一旋转臂限定 第二弯曲部，所述第一旋转臂在第一枢转点处联接到所述第一接合部件并且在第二枢转点处联接到所述第二接合部件，并且所述第二旋转臂在第三枢转点处联接到所述第一接合部件并且 在第四枢转点处到第二接合部件，以及第一互连臂和第二互连臂，第一互连臂相对于第一弯曲部连接到第一旋转臂，并且第二互连臂连接到第二旋转臂相对 到第二弯。
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公开(公告)号：US09050064B2
公开(公告)日：2015-06-09
申请号：US12881953
申请日：2010-09-14
CPC分类号： A61B17/0057 , A61B17/3417 , A61B17/3478 , A61B2017/00247 , A61B2017/00592 , A61B2017/00601 , A61B2017/00606 , A61B2017/00876 , A61B2017/306 , A61B2017/308 , A61B2017/3419 , A61B2017/3454 , A61B2017/3488 , A61B2018/00392 , A61M25/007
摘要： Systems for engaging a bodily tissue and methods of using the same. In at least one embodiment of an exemplary system for use with a vacuum source for engaging a tissue of the present disclosure, the system comprises an engagement catheter comprising a proximal end, a distal end, first and second lumens extending between the proximal end and the distal end, and a skirt operatively connected to the distal end, an inducer sheath having a proximal portion, a distal portion, and a lumen extending therethrough, the inducer sheath configured so that it is capable of insertion into the second lumen of the engagement catheter, a dilator comprising a tapered tip at a distal end and a hollow channel extending therethrough, the dilator sized and shaped for insertion into the lumen of the inducer sheath, and a vacuum port located at the proximal end of the engagement catheter, the vacuum port being operatively connected to the first lumen of the engagement catheter and capable of operative connection to a vacuum source. In various embodiments, the systems further comprise an inflatable balloon at or near the distal portion of the inducer sheath.
摘要翻译： 用于接合身体组织的系统及其使用方法。 在与用于接合本公开的组织的真空源一起使用的示例性系统的至少一个实施例中，该系统包括接合导管，其包括近端，远端，第一和第二腔，其在近端和 远端和可操作地连接到远端的裙部，具有近端部分，远侧部分和延伸穿过其中的内腔的诱导器护套，所述诱导器护套构造成使得其能够插入到接合导管的第二内腔中 ，包括在远端处的锥形尖端和延伸穿过其中的中空通道的扩张器，所述扩张器的尺寸和形状用于插入到所述诱导器鞘的内腔中，以及真空口，位于所述接合导管的近端，所述真空端口 可操作地连接到接合导管的第一内腔并能够与真空源连接。 在各种实施例中，系统还包括位于诱导器鞘的远端部分处或附近的可充气气囊。
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公开(公告)号：US08876776B2
公开(公告)日：2014-11-04
申请号：US13323174
申请日：2011-12-12
CPC分类号： A61N1/0592 , A61B17/00234 , A61B17/00491 , A61B17/0057 , A61B17/30 , A61B2017/00243 , A61B2017/00292 , A61B2017/00575 , A61B2017/00606 , A61B2017/0065 , A61B2017/306 , A61M5/14 , A61M25/0084 , A61M25/04 , A61M25/0662 , A61M2025/0004 , A61M2025/0039 , A61M2210/125
摘要： An engagement catheter for use with a vacuum source for engaging a tissue. An embodiment of the engagement catheter includes a first lumen extending between a proximal end and a distal end, a skirt operatively connected to the distal end, the skirt having a distal end with a circumference larger than the outer circumference of the engagement catheter, a suction port located at or near the distal end of the engagement catheter, the suction port configured to allow the distal end of the skirt to removably engage a surface of a bodily tissue, and a vacuum port located at the proximal end of the engagement catheter and capable of operative connection to a vacuum source, wherein when a vacuum source is operatively attached to the vacuum port, the skirt is capable of forming a reversible seal with the surface of the bodily tissue.
摘要翻译： 一种与用于接合组织的真空源一起使用的接合导管。 接合导管的一个实施例包括在近端和远端之间延伸的第一腔，可操作地连接到远端的裙部，裙部的远端具有比接合导管的外圆周更大的圆周， 位于所述接合导管的远端或靠近所述接合导管的远端的吸入口，所述吸入口被配置为允许所述裙部的远端可移除地接合身体组织的表面，以及位于所述接合导管的近端处的真空端口， 可操作地连接到真空源，其中当真空源可操作地附接到真空端口时，裙部能够与身体组织的表面形成可逆密封。
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公开(公告)号：US08702789B2
公开(公告)日：2014-04-22
申请号：US13151774
申请日：2011-06-02
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61B17/00491 , A61B17/12022 , A61B17/12113 , A61B17/12118 , A61B17/12186 , A61B17/12195 , A61B2017/00561 , A61B2017/00876 , A61B2017/00898 , A61B2090/064 , A61F2/82 , A61F2/88 , A61F2/89 , A61F2002/061 , A61F2002/075 , A61F2002/077 , A61F2002/823 , A61F2250/0013
摘要： Endoprosthesis assemblies and methods for using the same. In at least one embodiment of an endoprosthesis assembly of the present disclosure, the endoprosthesis assembly comprises an endoprosthesis comprising an impermeable inner wall defining an endoprosthesis lumen sized and shaped to permit fluid to flow therethrough, a distal balloon positioned at or near a distal end of the endoprosthesis, the distal balloon capable of inflation to anchor the distal end of the endoprosthesis within a luminal organ, and a proximal balloon positioned at or near a proximal end of the endoprosthesis, the proximal balloon capable of inflation to anchor the proximal end of the endoprosthesis within the luminal organ, wherein when the endoprosthesis assembly is positioned within the luminal organ at or near an aneurysm sac, inflation of the distal balloon and the proximal balloon effectively isolates the aneurysm sac and prevents fluid within the aneurysm sac from flowing past the distal balloon and the proximal balloon and into other areas of vasculature adjacent to the aneurysm sac.
摘要翻译： 内假体装配及其使用方法。 在本公开的内置假体组件的至少一个实施例中，内假体组件包括内置假体，其包括不透水的内壁，其限定尺寸和形状以允许流体流过其中的内置假腔，定位在或 内部假体，能够充气的远端球囊将内置假体的远端锚固在腔内器官内，以及定位在内假体近端处或附近的近端球囊，所述近端球囊能够充气以锚定内部假体的近端 腔内器官内的假体，其中当内假体组件位于动脉瘤囊或动脉瘤囊附近的腔内器官内时，远端球囊和近端球囊的充气有效地隔离动脉瘤囊并防止动脉瘤囊内的流体流过远端 气球和近端气球，进入其他脉管系统相邻区域 进入动脉瘤囊。
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公开(公告)号：US20130237743A1
公开(公告)日：2013-09-12
申请号：US13778020
申请日：2013-02-26
IPC分类号： A61M1/10
CPC分类号： A61M25/0147 , A61B17/0057 , A61B90/37 , A61B2017/00247 , A61B2017/003 , A61B2017/00584 , A61B2017/00592 , A61B2017/00601 , A61B2017/00606 , A61B2017/00628 , A61B2017/306 , A61B2017/308 , A61B2018/00392 , A61M1/1008 , A61M1/106 , A61M1/1068 , A61M1/107 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M1/127 , A61M25/00 , A61M25/003 , A61M25/0054 , A61M25/0074 , A61M25/0084 , A61M25/0136 , A61M25/0141 , A61M25/06 , A61M2025/0036 , A61M2025/0039 , A61M2025/004 , A61M2025/0089 , A61M2025/0096 , A61M2025/0681 , A61M2205/32 , A61M2205/33 , A61M2205/3303 , A61M2205/3331 , A61M2210/122 , A61M2210/125 , A61M2230/005 , A61N1/0587
摘要： Devices and methods for assisting cardiac function. In an exemplary embodiment of a device for assisting heart function of the present disclosure, the device comprises a first plate and an opposing second plate, each plate having an inner surface, a cardiac processor coupled to at least one of the first plate and the second plate, a bladder having an inner chamber and disposed between the inner surfaces, and a first catheter having a proximal end in communication with the inner chamber of the bladder and a distal end having a first pericardial balloon coupled thereto, wherein a gas and/or a liquid within the inner chamber of the bladder can be injected into the first pericardial balloon upon compression of the first plate relative to the second plate, and wherein the gas and/or the liquid can be removed from the first pericardial balloon upon retraction of the first plate relative to the second plate.
摘要翻译： 用于辅助心脏功能的装置和方法。 在用于辅助本公开的心脏功能的装置的示例性实施例中，该装置包括第一板和相对的第二板，每个板具有内表面，心脏处理器耦合到第一板和第二板中的至少一个 板，具有内室并设置在内表面之间的囊，以及第一导管，其具有与膀胱的内室连通的近端和具有与其结合的第一心包囊的远端，其中气体和/或 当第一板相对于第二板压缩时，囊内腔内的液体可以被注入到第一心包囊中，并且其中气体和/或液体可以在收回第一心包球时被从第一心包球囊移除 第一板相对于第二板。
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10.发明授权Devices, systems, and methods for percutaneous trans-septal left atrial appendage occlusion 有权用于经皮跨隔隔左心耳闭塞的装置，系统和方法公开(公告)号：US08480708B2
公开(公告)日：2013-07-09
申请号：US12863540
申请日：2009-01-06
IPC分类号： A61D1/00
CPC分类号： A61B17/12022 , A61B17/00491 , A61B17/0057 , A61B17/12013 , A61B17/12122 , A61B17/12181 , A61B17/12186 , A61B17/1227 , A61B17/1285 , A61B2017/00243 , A61B2017/00632 , A61B2017/0065 , A61B2017/00867 , A61B2017/22067 , A61B2017/306 , A61M25/007 , A61M25/10 , A61M2025/0086 , A61M2025/1052
摘要： Methods for occluding an atrial appendage. The steps of an exemplary method include introducing at least a portion of the first device in a heart, introducing at least a portion of a second device into a pericardial space surrounding the heart, positioning the balloon of the first device at least partially within an atrial appendage cavity, inflating the balloon to displace blood present within the atrial appendage cavity, positioning the loop of the second device around the atrial appendage, tightening the loop around the atrial appendage, deflating the balloon to allow for ultimate removal of the first device from the atrial appendage cavity, and separating the loop from the second device so that the loop remains positioned and tightened around the atrial appendage.
摘要翻译： 堵塞心房的方法 示例性方法的步骤包括在心脏中引入第一装置的至少一部分，将至少一部分第二装置引入围绕心脏的心包空间，将第一装置的气囊至少部分地置于心房内 附着腔，充气气球以置换存在于心耳腔内的血液，将第二装置的环定位在心耳附近，收紧围绕心耳的环，使气囊放气，以允许从第一装置 心房腔，并将环与第二装置分离，使得环保持定位并紧固在心耳附近。
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