公开(公告)号：US12232845B2

公开(公告)日：2025-02-25

申请号：US17294257

申请日：2019-11-14

Applicant: NUTECH VENTURES

Inventor： Steven M. Barlow ,  Jacob L. Greenwood

IPC: A61B5/00

Abstract: The present disclosure is directed to a tactile stimulation device. The tactile stimulation device can include at least one pneumatic switch, an applicator connected to the at least one pneumatic switch, and a controller operatively connected to the at least one pneumatic switch. The controller is configured to control the at least one pneumatic switch to connect the applicator to at least one of high pressure, vacuum pressure, and atmospheric pressure to stimulate a nerve ending of a user.

公开(公告)号：US20250043468A1

公开(公告)日：2025-02-06

申请号：US18790224

申请日：2024-07-31

Applicant: NUtech Ventures

Inventor： Mona Bavarian ,  Alyssa Grube

IPC: D02G3/44 ,  D02G3/02 ,  D02G3/36 ,  D04B1/16 ,  D04B1/22 ,  D06M11/73 ,  D06M15/61 ,  D06M23/08 ,  D06M101/12 ,  H01G11/26 ,  H01G11/52 ,  H01G11/58

Abstract: Systems and methods are presented for fabricating conductive protein-based yarns to produce textile-based supercapacitors (TSCs). Conductive wool yarns are created by coating wool yarn with Ti3C2Tx MXene flakes, or by coating wool yarn in MXene@conductive-polymer composite material, such as MXene@polypyrrole (PPY) or MXene@polyaniline (PANI). In some examples, the conductive polymer (e.g., polypyrrole (PPY) or polyaniline (PANI)) is polymerized in the presence of MXene flakes to yield conductive-polymer-coated MXene flakes (MXene@conductive-polymer), and then this material is then used to coat wool yarn to yield a conductive protein-based yarn. MXene materials offer a high conductivity, but tend to oxidize quickly, while conductive polymers have a lower conductivity, but are more chemically stable and less likely to oxidize. As such, it is presently recognized that, by combining these materials, a chemically stable and highly conductive composite material is formed that can be used to coat yarns to make TSCs.

公开(公告)号：US12076128B2

公开(公告)日：2024-09-03

申请号：US16819140

申请日：2020-03-15

Applicant: NUtech Ventures

Inventor： Mohammed Alwatban ,  Gregory R. Bashford

IPC: A61B5/0285 ,  A61B5/00 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/08 ,  A61B5/087 ,  C07K16/28 ,  A61K38/00

CPC classification number: A61B5/0285 ,  A61B5/0205 ,  A61B5/02133 ,  A61B5/082 ,  A61B5/087 ,  A61B5/4088 ,  A61B5/4836 ,  C07K16/28 ,  A61K38/00

Abstract: Provided here are methods of detecting compromised cerebrovascular reactivity in a subject and treating such subject. The method includes acquiring transcranial Doppler signals and cardiac measurements from the subject following a breath-hold maneuver and recording a test set of CBFV measurements. A breath-hold acceleration index is calculated based on a linear regression correlation of temporal variations of the mean velocity across all cardiac cycles during the breath-hold maneuver. The presence of compromised cerebrovascular reactivity in the subject is detected in response to variations in the breath-hold acceleration index of the subject as compared to a healthy individual performing breath-hold maneuver under similar conditions. If the subject has compromised cerebrovascular reactivity, a therapeutically effective compound is administered to the subject along with provision of behavioral modification regimen.

公开(公告)号：US12064759B2

公开(公告)日：2024-08-20

申请号：US17245381

申请日：2021-04-30

Applicant: NUtech Ventures ,  UNIVERSITY OF CONNECTICUT

Inventor： Ruiguo Yang ,  Arian Jaberi ,  Amir Monemian Esfahani ,  Ali Tamayol

IPC: B01L3/00 ,  C12M1/34 ,  C12N1/34

CPC classification number: B01L3/5025 ,  C12M41/46 ,  C12N1/34 ,  B01L2300/087 ,  B01L2300/0877 ,  B01L2300/0883 ,  C12N2513/00

Abstract: Microfluidic gradient generators that can create robust platforms that can not only be used for creating co-cultures of cells with various ratios, but also can simultaneously generate gradients of mechanical and chemical stresses. A chip utilizes microchambers embedded within channels to provide space for 3D cell culture and exposes these cells to gradients of mechanical shear stress and a chemical treatment.

公开(公告)号：US20240197819A1

公开(公告)日：2024-06-20

申请号：US18417206

申请日：2024-01-19

Applicant: NUtech Ventures

Inventor： Luwen Zhang ,  Chi Zhang

IPC: A61K38/16 ,  A61P25/28

CPC classification number: A61K38/162 ,  A61P25/28

Abstract: This document provides methods and materials for treating a mammal having Alzheimer's disease (AD). For example, one or more Zika virus (ZIKV) polypeptides can be administered to a mammal having, or at risk of developing, AD to treat the mammal.

公开(公告)号：US20240139865A1

公开(公告)日：2024-05-02

申请号：US18364942

申请日：2023-08-03

Applicant: NUtech Ventures, Inc.

Inventor： Craig Zuhlke ,  Andrew Reicks ,  Christos Argyropoulos ,  Andrew Butler ,  George Gogos ,  Dennis R. Alexander

IPC: B23K26/0622 ,  B23K26/12 ,  B23K26/352 ,  C23C24/08

CPC classification number: B23K26/0624 ,  B23K26/123 ,  B23K26/352 ,  C23C24/082

Abstract: A method for laser-processing a metallic surface to produce a functionalized metallic surface comprises: providing a material substrate having the surface; and applying a pulsed laser beam to a region of the surface, the pulsed laser beam being applied at a non-normal angle to the surface, wherein material in the region of the surface ablates due to the applied pulsed laser beam and wherein at least a portion of the ablated material redeposits on the surface to produce one or more material-coated structures angled at the non-normal angle with respect to the surface, wherein the surface having the one or more material-coated structures is the functionalized surface. The functionalized metallic surface has broadband directional emissivity independent of polarization.

公开(公告)号：US20240070838A1

公开(公告)日：2024-02-29

申请号：US18240879

申请日：2023-08-31

Applicant: NUtech Ventures

Inventor： Ziyad Smoqi ,  Prahalada Rao ,  Benjamin Bevans ,  Aniruddha Gaikwad

IPC: G06T7/00 ,  B22F12/90 ,  B33Y50/02

CPC classification number: G06T7/0004 ,  B22F12/90 ,  B33Y50/02 ,  G06T2207/20081

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer-storage media, for detection of defects in additive manufacturing. In some implementations, a method includes obtaining an image representing a volume of molten material; extracting one or more features from the image; providing the one or more features to a trained machine learning model; obtaining output from the trained machine learning model; and determining, using the output, a defect in a part.

公开(公告)号：US20240047144A1

公开(公告)日：2024-02-08

申请号：US18485556

申请日：2023-10-12

Applicant: Nutech Ventures ,  The University of North Carolina at Chapel Hill

Inventor： Jinsong Huang ,  Shuang Yang

IPC: H01G9/20 ,  C07F7/24 ,  H10K85/30

CPC classification number: H01G9/2027 ,  C07F7/24 ,  H01G9/2059 ,  H10K85/30 ,  H10K30/15

Abstract: Electronic devices comprising a first layer, said first layer comprising a perovskite material; and a coating layer disposed on a surface of said first layer; wherein said coating layer comprises a coating oxysalt. Also provided herein are perovskite materials comprising: a coating layer on at least a portion of a surface of said perovskite material; wherein said coating layer comprises a coating oxysalt. Further provided herein are methods for forming a coating layer on a surface of a perovskite material comprising steps of: exposing said surface to a fluid having a precursor oxysalt dissolved therein such that said coating layer forms on said surface via a chemical reaction between said perovskite material and said precursor oxysalt; wherein said coating layer comprises a coating oxysalt.

公开(公告)号：US20240030675A1

公开(公告)日：2024-01-25

申请号：US18356756

申请日：2023-07-21

Applicant: NUtech Ventures, Inc.

Inventor： Matthias Fuchs ,  Grayson Minnick

IPC: H01S4/00 ,  H01S3/0959 ,  H01S3/10 ,  H05H7/04

CPC classification number: H01S4/00 ,  H01S3/0959 ,  H01S3/10061 ,  H05H7/04 ,  H05H2007/041

Abstract: Systems and methods for generating longitudinally modulated (micro-bunched) electron bunches and for generating coherent radiation by the emission from relativistic electrons with a density that is longitudinally modulated (micro-bunched) with a spatial dimension that is significantly below the wavelength of the emitted radiation. The light source includes a high-brightness relativistic electron beam that interacts in a magnetic structure (linear or helical undulator or wiggler) or an electromagnetic structure with a pulse of high-power electro-magnetic wave (modulation laser pulse). The interaction leads to a large energy-modulation of the electron bunch which is transformed into a spatial modulation by an energy-dispersive element that can be the same undulator.

公开(公告)号：US20230410977A1

公开(公告)日：2023-12-21

申请号：US18268721

申请日：2021-12-22

Applicant: NUtech Ventures

Inventor： Alexandra Crook ,  Aline De Lima Leite ,  Thomas Payne ,  Fatema Bhinderwala ,  Robert Powers

IPC: G16H20/40 ,  A61N5/10 ,  G01N33/574 ,  G01N33/68 ,  G16H10/40

CPC classification number: G16H20/40 ,  A61N5/103 ,  G01N33/57488 ,  G01N33/6848 ,  G16H10/40

Abstract: This document relates to methods and materials for assessing radiation exposure. For example, methods and materials that can be used to determine whether a mammal (e.g., a human) has been exposed to radiation and/or whether a mammal (e.g., a human) is at risk of developing one or more radiation injuries (e.g., cutaneous radiation injury (CRI) and/or acute radiation syndrome (ARS)) following radiation exposure (e.g., radiation therapy) are provided.