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公开(公告)号:US08622991B2
公开(公告)日:2014-01-07
申请号:US12450246
申请日:2008-03-19
申请人: Benny Pesach , Gabriel Bitton , Ram Weiss , Ron Nagar
发明人: Benny Pesach , Gabriel Bitton , Ram Weiss , Ron Nagar
CPC分类号: A61M5/1723 , A61B18/14 , A61B18/1492 , A61B18/18 , A61F7/007 , A61F7/10 , A61H9/0057 , A61H23/00 , A61M5/14244 , A61M5/158 , A61M5/16831 , A61M37/0092 , A61M2005/1581 , A61M2005/1726 , A61M2205/05 , A61M2205/051 , A61M2205/052 , A61M2205/058 , A61N1/30 , A61N1/406 , A61N2/002 , A61N5/062 , A61N7/00 , A61N2005/0645 , G06F19/00
摘要: Systems, devices and methods for delivery of a chemical substance to the body of the patient are provided. Such embodiments may include an infusion catheter configured to be inserted into tissue, a catheter securing element configured to be adhered to the skin of the patient and further configured to secure the infusion catheter to the skin, a drug delivery pump configured to infuse a drug into the infusion catheter for delivery to a drug infused region on the body of the patient, and a treatment element configured to apply a treatment to the drug infused region to improve pharmacodynamics of the drug during a period of delivery of the drug to the patient.
摘要翻译: 提供了将化学物质递送到患者体内的系统,装置和方法。 这样的实施例可以包括构造成插入组织中的输注导管,导管固定元件,其构造成粘附到患者的皮肤上,并进一步被配置成将输注导管固定到皮肤上;药物输送泵,被配置为将药物注入 用于输送到患者身体上的药物输注区域的输注导管,以及配置成对药物输注区域施加治疗以改善药物递送到患者期间药物的药效学的治疗元件。
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公开(公告)号:US20110288527A1
公开(公告)日:2011-11-24
申请号:US13127823
申请日:2009-11-06
申请人: Benny Pesach , Gabriel Bitton , Ron Nagar , Ram Weiss
发明人: Benny Pesach , Gabriel Bitton , Ron Nagar , Ram Weiss
IPC分类号: A61M37/00
CPC分类号: A61M5/44 , A61B2018/00005 , A61B2090/0803 , A61F7/007 , A61F7/02 , A61F2007/0093 , A61F2007/0096 , A61F2007/0226 , A61M5/003 , A61M5/20 , A61M5/427 , A61M2205/273 , A61M2205/3368 , A61M2205/3653 , A61M2209/00
摘要: A therapeutic treatment device, system and method for improving administration of a temperature sensitive drug into a tissue on the body of a patient at a drug injection site are disclosed. The device includes a treatment element with a controllable heating element in temperature communicative contact with the tissue adjacent to the drug injection site. The controllable heating element is configured to heat the tissue adjacent to the drug injection site to a controllable temperature but does not heat the injected drug above a predetermined limiting temperature, above which degradation of the injected drug may occur.
摘要翻译: 公开了一种治疗装置,系统和方法,用于在药物注射部位改善对患者体内的组织中的感温药物的给药。 该装置包括具有可控加热元件的处理元件,其与邻近药物注射部位的组织温度交互接触。 可控制加热元件被配置为将邻近药物注射部位的组织加热到可控温度,但是不将注射的药物加热到预定的极限温度以上,在该极限温度以上可能发生注射药物的降解。
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公开(公告)号:US20110184342A1
公开(公告)日:2011-07-28
申请号:US12809425
申请日:2008-12-18
申请人: Benny Pesach , Gabriel Bitton , Ron Nagar , Ram Weiss
发明人: Benny Pesach , Gabriel Bitton , Ron Nagar , Ram Weiss
IPC分类号: A61M5/00
CPC分类号: A61M5/1723 , A61M5/14248 , A61M2005/14296 , A61M2005/1726 , A61M2205/3368 , A61M2205/50 , A61M2205/60 , A61M2230/201 , A61M2230/50 , A61M2230/63
摘要: An apparatus and a system for controlling and/or managing administration of a drug to a body of a patient. The apparatus includes a drug infusion device configured to deliver drug at a predetermined location in the body of the patient, at least one sensor disposed in the drug infusion device and configured to measure a. corresponding property related to the patient and selected from the group consisting of physiological properties, biochemical properties, environmental properties and drug-related properties, a controller disposed in the drug infusion device and configured to receive from the at least one sensor data representative of the measured corresponding property and based on the received data, determine a drug delivery rate. The drug delivery device is configured to deliver the drug to the body of the patient based on the determined drug delivery rate.
摘要翻译: 一种用于控制和/或管理药物对患者体内的药物的装置和系统。 该装置包括药物输注装置,其配置成在患者体内的预定位置输送药物,至少一个传感器设置在药物输注装置中并且被配置为测量a。 与患者相关的并且选自生理特性,生物化学性质,环境特性和药物相关性质的对应性质,设置在药物输注装置中并被配置为从所述至少一个传感器接收表示所测量的数据的数据 相应的财产,并根据收到的数据,确定药物递送率。 药物递送装置被配置为基于确定的药物递送速率将药物递送到患者的身体。
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公开(公告)号:US20100292557A1
公开(公告)日:2010-11-18
申请号:US12450250
申请日:2008-03-19
申请人: Benny Pesach , Gabriel Bitton , Ram Weiss , Ron Nagar
发明人: Benny Pesach , Gabriel Bitton , Ram Weiss , Ron Nagar
IPC分类号: A61B5/00
CPC分类号: A61B5/1495 , A61B5/14532 , A61B5/14865 , A61B5/1491
摘要: Embodiments of the present disclosure present systems, devices and methods for ISF glucose monitoring that more accurately reflects the blood glucose levels by introducing a treatment element allowing stable and accurate prediction of blood glucose levels based measured glucose levels from interstitial fluid.
摘要翻译: 本公开的实施例提供了用于ISF葡萄糖监测的系统,装置和方法,其通过引入治疗元件更准确地反映血糖水平,所述治疗元件允许基于来自间质液的测量的葡萄糖水平来稳定和准确地预测血糖水平。
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公开(公告)号:US09220837B2
公开(公告)日:2015-12-29
申请号:US11821230
申请日:2007-06-21
申请人: Benny Pesach , Ron Nagar , Gabriel Bitton , Ram Weiss
发明人: Benny Pesach , Ron Nagar , Gabriel Bitton , Ram Weiss
IPC分类号: A61M5/142 , A61M5/158 , A61M5/168 , A61M5/172 , A61M5/20 , A61B18/14 , A61B18/18 , A61F7/00 , A61M5/14 , A61M39/10 , A61N1/30 , A61N7/00 , A61N5/06 , A61M5/42 , A61B18/08 , A61B18/20
CPC分类号: A61M5/14244 , A61B18/08 , A61B18/14 , A61B18/1477 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2018/1425 , A61F7/007 , A61M5/1413 , A61M5/158 , A61M5/16831 , A61M5/1723 , A61M5/20 , A61M5/422 , A61M2005/1581 , A61M2005/1726 , A61M2039/1022 , A61M2205/05 , A61M2205/051 , A61M2205/052 , A61M2205/058 , A61M2205/8206 , A61N1/30 , A61N7/00 , A61N2005/0645
摘要: A method and a device for a delivery of a chemical substance to the body of the patient are provided. The device includes an infusion catheter configured to be inserted into a tissue, a catheter securing element configured to be adhered to the skin of the patient and further configured to secure the infusion catheter to the skin, a drug delivery pump configured to infuse a drug into the infusion catheter for delivery to a drug infused region on the body of the patient, and a treatment element configured to apply a treatment to the drug infused region to improve pharmacodynamics of the drug during a period of delivery of the drug to the patient.
摘要翻译: 提供了一种将化学物质输送到患者体内的方法和装置。 该装置包括构造成插入到组织中的输注导管,导管固定元件,其构造成粘附到患者的皮肤上,并进一步构造成将输注导管固定到皮肤上;药物输送泵,被配置为将药物注入 用于输送到患者身体上的药物输注区域的输注导管,以及配置成对药物输注区域施加治疗以改善药物递送到患者期间药物的药效学的治疗元件。
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公开(公告)号:US20130268089A1
公开(公告)日:2013-10-10
申请号:US13816117
申请日:2011-08-09
申请人: Ram Weiss , Menachem P. Weiss
发明人: Ram Weiss , Menachem P. Weiss
IPC分类号: A61F2/04
CPC分类号: A61F2/04 , A61F5/0079 , A61F2002/044 , A61F2002/045
摘要: An inert adapter for supporting gastric devices. The adapter is connected to the inner lining of the stomach to encircle the esophageal sphincter and supports a treatment element. The treatment element is operated only after at least the healing period of the connection has passed. The adapter and the treatment element may be endoscopically inserted in a single action, and the activation of the treatment element may be carried out externally or internally by the dissolution of a dissolvable element. The adapter may support various treatment elements, such as an intake limiting pouch or an anti GERD device, and may additionally deliver drugs. Allowing a late activation of the device without additional intervention or even supervision simplifies gastric device applications and enhances their safety.
摘要翻译: 用于支持胃装置的惰性适配器。 适配器连接到胃的内衬以包围食管括约肌并支撑治疗元件。 处理元件仅在至少连接的愈合时间过去后才能运行。 适配器和处理元件可以内窥镜插入单一动作中,并且处理元件的激活可以通过溶解元素的溶解在外部或内部进行。 适配器可以支持各种治疗元件,例如进气限制袋或抗GERD装置,并且还可以递送药物。 允许晚期启动设备,无需额外的干预或甚至监督,简化了胃装置应用并增强了其安全性。
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公开(公告)号:US08409133B2
公开(公告)日:2013-04-02
申请号:US12809425
申请日:2008-12-18
申请人: Benny Pesach , Gabriel Bitton , Ron Nagar , Ram Weiss
发明人: Benny Pesach , Gabriel Bitton , Ron Nagar , Ram Weiss
IPC分类号: A61N1/08
CPC分类号: A61M5/1723 , A61M5/14248 , A61M2005/14296 , A61M2005/1726 , A61M2205/3368 , A61M2205/50 , A61M2205/60 , A61M2230/201 , A61M2230/50 , A61M2230/63
摘要: An apparatus and a system for controlling and/or managing administration of a drug to a body of a patient. The apparatus includes a drug infusion device configured to deliver drug at a predetermined location in the body of the patient, at least one sensor disposed in the drug infusion device and configured to measure a. corresponding property related to the patient and selected from the group consisting of physiological properties, biochemical properties, environmental properties and drug-related properties, a controller disposed in the drug infusion device and configured to receive from the at least one sensor data representative of the measured corresponding property and based on the received data, determine a drug delivery rate. The drug delivery device is configured to deliver the drug to the body of the patient based on the determined drug delivery rate.
摘要翻译: 一种用于控制和/或管理药物对患者体内的药物的装置和系统。 该装置包括药物输注装置,其配置成在患者体内的预定位置输送药物,至少一个传感器设置在药物输注装置中并且被配置为测量a。 与患者相关的并且选自生理特性,生物化学性质,环境特性和药物相关性质的对应性质,设置在药物输注装置中并被配置为从所述至少一个传感器接收表示所测量的数据的数据 相应的财产,并根据收到的数据,确定药物递送率。 药物递送装置被配置为基于确定的药物递送速率将药物递送到患者的身体。
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公开(公告)号:US08961458B2
公开(公告)日:2015-02-24
申请号:US13127823
申请日:2009-11-06
申请人: Benny Pesach , Gabriel Bitton , Ron Nagar , Ram Weiss
发明人: Benny Pesach , Gabriel Bitton , Ron Nagar , Ram Weiss
IPC分类号: A61F7/12 , A61M31/00 , A61F7/02 , A61M5/00 , A61M5/42 , A61B18/00 , A61B19/00 , A61F7/00 , A61M5/20
CPC分类号: A61M5/44 , A61B2018/00005 , A61B2090/0803 , A61F7/007 , A61F7/02 , A61F2007/0093 , A61F2007/0096 , A61F2007/0226 , A61M5/003 , A61M5/20 , A61M5/427 , A61M2205/273 , A61M2205/3368 , A61M2205/3653 , A61M2209/00
摘要: A therapeutic treatment device, system and method for improving administration of a temperature sensitive drug into a tissue on the body of a patient at a drug injection site are disclosed. The device includes a treatment element with a controllable heating element in temperature communicative contact with the tissue adjacent to the drug injection site. The controllable heating element is configured to heat the tissue adjacent to the drug injection site to a controllable temperature but does not heat the injected drug above a predetermined limiting temperature, above which degradation of the injected drug may occur.
摘要翻译: 公开了一种治疗装置,系统和方法,用于在药物注射部位改善对患者体内的组织中的感温药物的给药。 该装置包括具有可控加热元件的处理元件,其与邻近药物注射部位的组织温度交互接触。 可控制加热元件被配置为将邻近药物注射部位的组织加热到可控温度,但是不将注射的药物加热到预定的极限温度以上,在该极限温度以上可能发生注射药物的降解。
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公开(公告)号:US20100152644A1
公开(公告)日:2010-06-17
申请号:US12450246
申请日:2008-03-19
申请人: Benny Pesach , Gabriel Bitton , Ram Weiss , Ron Nagar
发明人: Benny Pesach , Gabriel Bitton , Ram Weiss , Ron Nagar
CPC分类号: A61M5/1723 , A61B18/14 , A61B18/1492 , A61B18/18 , A61F7/007 , A61F7/10 , A61H9/0057 , A61H23/00 , A61M5/14244 , A61M5/158 , A61M5/16831 , A61M37/0092 , A61M2005/1581 , A61M2005/1726 , A61M2205/05 , A61M2205/051 , A61M2205/052 , A61M2205/058 , A61N1/30 , A61N1/406 , A61N2/002 , A61N5/062 , A61N7/00 , A61N2005/0645 , G06F19/00
摘要: Systems, devices and methods for delivery of a chemical substance to the body of the patient are provided. Such embodiments may include an infusion catheter configured to be inserted into tissue, a catheter securing element configured to be adhered to the skin of the patient and further configured to secure the infusion catheter to the skin, a drug delivery pump configured to infuse a drug into the infusion catheter for delivery to a drug infused region on the body of the patient, and a treatment element configured to apply a treatment to the drug infused region to improve pharmacodynamics of the drug during a period of delivery of the drug to the patient.
摘要翻译: 提供了将化学物质递送到患者体内的系统,装置和方法。 这样的实施例可以包括构造成插入组织中的输注导管,导管固定元件,其构造成粘附到患者的皮肤上,并进一步被配置成将输注导管固定到皮肤上;药物输送泵,被配置为将药物注入 用于输送到患者身体上的药物输注区域的输注导管,以及配置成对药物输注区域施加治疗以改善药物递送到患者期间药物的药效学的治疗元件。
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公开(公告)号:US20070123809A1
公开(公告)日:2007-05-31
申请号:US11627189
申请日:2007-01-25
申请人: Ram Weiss , Menachem Weiss
发明人: Ram Weiss , Menachem Weiss
IPC分类号: A61H7/00
CPC分类号: A61H21/00 , A61H23/0218
摘要: A medical device includes a device body for insertion into an organ of a patient and one or more arms, which are attached to the device body and are arranged to extend outward from the device body within the organ so as to contact respective points-of-contact on an inner surface of the organ, and to apply a repetitive motion at one or more of the points-of-contact.
摘要翻译: 医疗装置包括用于插入到患者器官中的装置主体和一个或多个臂,所述手臂附接到装置主体并被布置成从器官体内的器官内部延伸出来, 在器官的内表面上接触,并且在一个或多个接触点处施加重复运动。
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