公开(公告)号：US09299655B2

公开(公告)日：2016-03-29

申请号：US13988327

申请日：2011-11-18

申请人： Yashodhan Vijay Moghe ,  Andrew Terry ,  Andrew James Read ,  Steven Grant Duvall

发明人： Yashodhan Vijay Moghe ,  Andrew Terry ,  Andrew James Read ,  Steven Grant Duvall

IPC分类号： H01L29/00 ,  H01L23/522 ,  H01L23/60 ,  H01L27/06 ,  H01L23/48 ,  H01L27/02 ,  H01L49/02

CPC分类号： H01L27/0292 ,  H01L23/48 ,  H01L23/5222 ,  H01L23/5223 ,  H01L23/60 ,  H01L27/0207 ,  H01L27/0248 ,  H01L27/0255 ,  H01L27/0629 ,  H01L28/40 ,  H01L29/0607 ,  H01L2224/32245 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2224/49171 ,  H01L2224/73265 ,  H01L2924/181 ,  H01L2924/00014 ,  H01L2924/00 ,  H01L2924/00012

摘要： An integrated circuit, including at least two integrated circuit portions mutually spaced on a single electrically insulating die and at least one coupling region on the die to provide capacitive coupling between the otherwise mutually isolated integrated circuit portions, the integrated circuit portions being formed by a plurality of layers on the single die, the layers including metal and dielectric layers and at least one semiconductor layer; wherein at least one of the dielectric layers extends from the integrated circuit portions across the coupling region and at least a corresponding one of the metal layers and/or at least one semiconductor layer extends from each of the integrated circuit portions and partially across the coupling region to form capacitors therein and thereby provide the capacitive coupling between the integrated circuit portions.

摘要翻译： 一种集成电路，包括在单个电绝缘管芯上相互间隔开的至少两个集成电路部分和管芯上的至少一个耦合区域，以在另外相互隔离的集成电路部分之间提供电容耦合，所述集成电路部分由多个 层，包括金属和介电层以及至少一个半导体层; 其中所述电介质层中的至少一个从所述集成电路部分延伸穿过所述耦合区域，并且所述金属层中的至少一个和/或至少一个半导体层从所述集成电路部分中的每一个延伸并部分地跨过所述耦合区域 以在其中形成电容器，从而提供集成电路部分之间的电容耦合。

公开(公告)号：US09127059B2

公开(公告)日：2015-09-08

申请号：US13391619

申请日：2010-08-20

申请人： Julian Alexander Barden ,  Neil Brewis ,  Philip Jones ,  Steven Grant

发明人： Julian Alexander Barden ,  Neil Brewis ,  Philip Jones ,  Steven Grant

IPC分类号： C07K16/28

CPC分类号： C07K16/28 ,  C07K16/30 ,  C07K2317/34 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/569 ,  C07K2317/74 ,  C07K2317/76 ,  C07K2317/92

摘要： The invention relates to an antigen binding site for binding to a P2X7 receptor, the antigen binding site being defined by general formula 1: FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4

摘要翻译： 本发明涉及用于结合P2X7受体的抗原结合位点，抗原结合位点由通式1定义：FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4

公开(公告)号：US09044000B1

公开(公告)日：2015-06-02

申请号：US13567048

申请日：2012-08-04

申请人： Steven Grant Lumsden

发明人： Steven Grant Lumsden

IPC分类号： A01K83/06

CPC分类号： A01K83/06

摘要： A spinning device for covering and maintaining the front face of a bait fish resulting in greater utility, ease of use and bait durability. The device comprises a cup having a planar face and cylindrical wall adapted to extend rearward along the sides of the bait fish when the inside surface mates a “plug-cut” bait fish frontal face. The device has compound angled surfaces, a planar surface between multiple apertures enabling secure spin options and stability due to deep cup depth seating as well as enlarged flange apertures capable of accepting a standard toothpick. A trio of spaced apart apertures are formed in the device's frontal face allowing for a fishing leader terminating in one or more hooks extending through the device into the bait fish's body. The rotational spin rate of the device is determined by which of the three apertures the leader passes.

摘要翻译： 一种用于覆盖和保持诱饵鱼的前脸的旋转装置，其具有更大的实用性，易于使用和诱饵耐久性。 该装置包括具有平面的杯和圆柱形壁，当内表面配合“插塞式”诱饵鱼的正面时，适于沿着饵鱼的侧面向后延伸。 该装置具有复合的倾斜表面，多个孔之间的平坦表面，使得能够确保旋转选项和由于深杯深度座位而具有的稳定性以及能够接受标准牙签的扩大的凸缘孔。 在装置的正面中形成三分之一的间隔开的孔，从而允许钓鱼导向​​器终止在延伸穿过装置的诱饵鱼体内的一个或多个钩中。 设备的旋转旋转速率由引导者通过的三个孔中的哪一个确定。

公开(公告)号：US08962376B2

公开(公告)日：2015-02-24

申请号：US13265850

申请日：2010-04-21

申请人： Petar Branko Atanackovic ,  Steven Grant Duvall

发明人： Petar Branko Atanackovic ,  Steven Grant Duvall

IPC分类号： H01L21/00 ,  H01L31/0224 ,  H01L31/042 ,  H01L31/028 ,  H01L27/142 ,  H01L31/052 ,  H01L31/068 ,  H01L31/075 ,  H01L31/18

CPC分类号： H01L31/068 ,  H01L31/022441 ,  H01L31/028 ,  H01L31/03921 ,  H01L31/042 ,  H01L31/047 ,  H01L31/0475 ,  H01L31/0508 ,  H01L31/056 ,  H01L31/0682 ,  H01L31/075 ,  H01L31/1804 ,  H01L31/202 ,  H01L31/208 ,  Y02E10/52 ,  Y02E10/547 ,  Y02E10/548 ,  Y02P70/521

摘要： An optoelectronic device, including a semiconductor body having a surface to receive photons and a plurality of doped regions of opposite doping polarities, the doped regions extending substantially from the surface of the semiconductor body and into the semiconductor body, and being arranged in one or more pairs of opposite doping polarities such that each pair of doped regions forms a corresponding space charge region having a corresponding electric field therein, the space charge region extending substantially from the surface of the semiconductor body and into the semiconductor body such that photons entering the semiconductor body through the surface and travelling along paths within the space charge region generate electron-hole pairs in the space charge region that are separated in opposing directions substantially orthogonal to the photon paths by the electric field and collected by the corresponding pair of doped regions, thereby providing an electrical current to be conducted from the device.

摘要翻译： 一种光电器件，包括具有接收光子的表面和具有相反掺杂极性的多个掺杂区域的半导体本体，所述掺杂区域基本上从半导体本体的表面延伸并进入半导体本体，并被布置在一个或多个 成对的相反的掺杂极性，使得每对掺杂区域在其中形成具有相应电场的相应的空间电荷区域，空间电荷区域基本上从半导体本体的表面延伸并进入半导体本体，使得进入半导体体的光子 通过该表面并且沿着空间电荷区域内的路径行进，在空间电荷区域中产生电子 - 空穴对，该空间电荷区域通过电场在与光子路径基本正交的相反方向上分离并由相应的一对掺杂区域收集，从而提供 要进行的电流 从设备。

公开(公告)号：US08092800B2

公开(公告)日：2012-01-10

申请号：US11886492

申请日：2006-03-10

申请人： Antonio Cassone ,  Flavia de Bernardis ,  Steven Grant ,  Haiqun Liu

发明人： Antonio Cassone ,  Flavia de Bernardis ,  Steven Grant ,  Haiqun Liu

IPC分类号： A61K39/00 ,  A61K39/395 ,  A61K39/38

CPC分类号： C07K16/14 ,  A61K2039/505 ,  A61K2039/54 ,  C07K16/40 ,  C07K2317/21 ,  C07K2317/31 ,  C07K2317/569 ,  C07K2317/76

摘要： This invention relates to domain antibodies. In particular, it relates to domain antibodies (dAbs) that recognize virulence traits of Candida spp. and confer passive protection against candidiasis.

摘要翻译： 本发明涉及结构域抗体。 特别涉及识别假丝酵母属的毒力特征的结构域抗体（dAb）。 并给予针对念珠菌病的被动保护。

公开(公告)号：US20110172400A1

公开(公告)日：2011-07-14

申请号：US12941870

申请日：2010-11-08

申请人： Steven Grant ,  Haiqun Liu ,  Kevin Moulder

发明人： Steven Grant ,  Haiqun Liu ,  Kevin Moulder

IPC分类号： C07K16/18

CPC分类号： C07K16/2875 ,  C07K2317/565 ,  C07K2317/569 ,  C07K2317/76

摘要： The invention relates to antibody polypeptides that monovalently bind CD4OL. Antibody polypeptides that are monovalent for binding of CD4OL can inhibit CD4OL activity while avoiding potential undesirable effects that can occur with antibodies capable of divalent or multivalent binding of DC4OL. in one aspect, a monovalent anti-CD4OL antibody polypeptide consists of or comprises a single immunoglobulin variable domain that specifically binds and antagonizes the activity of DC4OL, preferably without substantially agonizing CD40 activity. In another aspect, the monovalent anti-CD4OL antibody polypeptide is a human antibody polypeptide. The invention further encompasses methods of antagonizing CD40/CD4OL interactions in an individual and methods of treating diseases or disorders involving CD40/DC4OL interactions, the methods involving administering a monovalent anti-CD4OL antibody polypeptide to the individual.

摘要翻译： 本发明涉及单价结合CD4OL的抗体多肽。 用于结合CD4OL的单价抗体多肽可以抑制CD4OL活性，同时避免可能与能够进行DC4OL的二价或多价结合的抗体发生的不良反应。 在一个方面，单价抗-T1OL抗体多肽由特异性结合并拮抗DC4OL的活性的单个免疫球蛋白可变区组成或包含，优选不具有实质上激动的CD40活性。 另一方面，单价抗-TOLOL抗体多肽是人抗体多肽。 本发明还包括拮抗个体中CD40 / CD4OL相互作用的拮抗作用的方法以及治疗涉及CD40 / DC4OL相互作用的疾病或病症的方法，所述方法包括对个体施用单价抗-TOLOL抗体多肽。

公开(公告)号：US07928304B2

公开(公告)日：2011-04-19

申请号：US10586144

申请日：2005-01-14

申请人： Donald H. Eason ,  Steven Grant Fisher

发明人： Donald H. Eason ,  Steven Grant Fisher

IPC分类号： G10D13/02

CPC分类号： G10D13/00 ,  F16B7/0486 ,  Y10T403/32426 ,  Y10T403/32467 ,  Y10T403/32532 ,  Y10T403/535 ,  Y10T403/66 ,  Y10T403/69 ,  Y10T403/7062 ,  Y10T403/7071

摘要： At least one embodiment of the inventive technology may be a support apparatus that includes at least two item support rails supported by support legs coupled thereto by pivot coupler apparatus that enable rotatable motion of a coupled support rail about a substantially vertical axis, where at least one of the item support rails is a non-horizontal item support rail, and where a cable passes through at least a portion of one or more of the support rails. In certain embodiments, the couplers may be height adjust couplers that enable substantially purely vertical, translatory height adjustment of coupled support rails and/or the couplers may couple item support rails to rail support legs at an angle other than ninety degrees. Items that may be supported include but are not limited to electronic percussion instruments.

摘要翻译： 本发明技术的至少一个实施例可以是一种支撑装置，其包括至少两个物品支撑轨道，所述至少两个物品支撑轨道由支撑腿支撑，所述支撑腿通过枢转耦合器装置连接到支撑腿，所述枢转耦合器装置使耦合的支撑轨道围绕基本上垂直的轴线可旋转 物品支撑轨道是非水平物品支撑轨道，并且其中电缆穿过一个或多个支撑轨道的至少一部分。 在某些实施例中，耦合器可以是高度调节耦合器，其使得能够实现基本上纯耦合的支撑轨道的垂直，平移高度调节和/或耦合器可以以不同于九十度的角度将物品支撑轨道连接到轨道支撑腿。 可能支持的项目包括但不限于电子打击乐器。

公开(公告)号：US20090291081A1

公开(公告)日：2009-11-26

申请号：US12006068

申请日：2007-12-28

申请人： Chung-Ming Hsieh ,  Bradford L. McRae ,  Yuliya Kutskova ,  John E. Memmott ,  Michael Roguska ,  Ian Tomlinson ,  Carrie Enever ,  Steven Grant ,  Mihriban Tuna

发明人： Chung-Ming Hsieh ,  Bradford L. McRae ,  Yuliya Kutskova ,  John E. Memmott ,  Michael Roguska ,  Ian Tomlinson ,  Carrie Enever ,  Steven Grant ,  Mihriban Tuna

IPC分类号： A61K39/395 ,  C07K16/18 ,  C12N15/11 ,  C12N15/00 ,  C12N5/06 ,  C12P21/04 ,  A61P37/00

CPC分类号： C07K16/468 ,  A61K39/3955 ,  A61K45/06 ,  C07K16/245 ,  C07K2317/569 ,  C07K2317/92

摘要： The invention provides an isolated, dual-specific antibody, or an antigen-binding portion thereof, which is specific for human IL-1α and human IL-1β. The dual specific antibodies of the invention also neutralize both human IL-1α and human IL-1β. The invention also provides domain antibodies (dAbs) specific for human IL-1α and human IL-1β.

摘要翻译： 本发明提供了对人IL-1α和人IL-1β特异的分离的双重特异性抗体或其抗原结合部分。 本发明的双重特异性抗体也中和人IL-1α和人IL-1beta。 本发明还提供了对人IL-1α和人IL-1β特异性的结构域抗体（dAb）。

公开(公告)号：US20090258012A1

公开(公告)日：2009-10-15

申请号：US12409617

申请日：2009-03-24

申请人： Olga Ignatovich ,  Rudolf Maria Theodora de Wildt ,  Benjamin Woolven ,  Steven Grant ,  Philip C. Jones ,  Amrik Basran ,  Neil Brewis

发明人： Olga Ignatovich ,  Rudolf Maria Theodora de Wildt ,  Benjamin Woolven ,  Steven Grant ,  Philip C. Jones ,  Amrik Basran ,  Neil Brewis

IPC分类号： A61K39/395 ,  A61P19/02

CPC分类号： C07K16/468 ,  A61K47/6879 ,  C07K16/005 ,  C07K16/18 ,  C07K16/22 ,  C07K16/241 ,  C07K16/30 ,  C07K16/40 ,  C07K2317/21 ,  C07K2317/31 ,  C07K2317/34 ,  C07K2317/55 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2319/00

摘要： The invention relates to compositions and methods for treating inflammatory disorders. More specifically, the invention relates to antibody compositions and their use in the treatment of inflammatory disorders.

摘要翻译： 本发明涉及用于治疗炎症性疾病的组合物和方法。 更具体地，本发明涉及抗体组合物及其在治疗炎症性疾病中的用途。

公开(公告)号：US07146445B2

公开(公告)日：2006-12-05

申请号：US10763784

申请日：2004-01-23

申请人： Robert Scott Appleton ,  Patrick Steven Grant ,  David Etzkorn

发明人： Robert Scott Appleton ,  Patrick Steven Grant ,  David Etzkorn

IPC分类号： G06F13/00 ,  G06F13/20

CPC分类号： G06F13/4081

摘要： A test apparatus for telecommunication equipment includes motherboard that executes a resident operation control mechanism, so that the test apparatus exhibits default hardware functionality. However, if a daughtercard has been plugged into the motherboard, the motherboard ignores the default firmware and executes whatever replacement operation control software is provided on the daughtercard—causing the test apparatus to acquire a hardware functionality exclusive of the motherboard default.

摘要翻译： 用于电信设备的测试设备包括执行驻留操作控制机构的主板，使得测试设备呈现出默认的硬件功能。 然而，如果子卡已插入主板，则主板将忽略默认固件，并执行子卡上提供的任何替换操作控制软件，导致测试设备获取独占于主板默认值的硬件功能。