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    DEVICES AND METHODS FOR OPTOELECTRONIC MANIPULATION OF SMALL PARTICLES
    1.
    发明申请
    DEVICES AND METHODS FOR OPTOELECTRONIC MANIPULATION OF SMALL PARTICLES 有权
    用于光电子操作小颗粒的装置和方法

    公开(公告)号：US20100206731A1

    公开(公告)日：2010-08-19

    申请号：US12702137

    申请日：2010-02-08

    申请人： Aldrich N.K. Lau ,  Joon Mo Yang ,  Huan L. Phan ,  Steven W. Sherwood ,  Hans A. Fuernkranz

    发明人： Aldrich N.K. Lau ,  Joon Mo Yang ,  Huan L. Phan ,  Steven W. Sherwood ,  Hans A. Fuernkranz

    IPC分类号： B03C11/00

    CPC分类号： B03C5/026 ,  B03C5/005 ,  B03C5/028 ,  C07K1/26 ,  G01N27/305

    摘要： A method for sorting cells in a biological sample comprising a first type of cells and a second type of cells may comprise introducing the biological sample into a chamber comprising a first surface and a second surface, wherein the first surface is associated with a transparent electrode and the second surface is associated with a photoconductive portion of an electrode. The method may further comprise moving incident light and the photoconductive portion relative to one another so as to illuminate regions of the photoconductive portion and modulate an electric field in the chamber in proximity to the illuminated regions. The method may further comprise separating the first type of cells from the second type of cells in the chamber via dielectrophoretic movement of the first type of cells and the second type of cells caused by the modulated electric field, wherein a dielectrophoretic characteristic of at least one of the first type of cells and the second type of cells has been modified.

    摘要翻译： 用于分选生物样品中包含第一类型细胞和第二类型细胞的细胞的方法可以包括将生物样品引入包含第一表面和第二表面的室中，其中第一表面与透明电极相关联， 第二表面与电极的光电导部分相关联。 该方法还可以包括相对于彼此移动入射光和光电导部分，以照射光电导部分的区域并且调制在邻近照明区域的室中的电场。 该方法还可以包括通过由调制电场引起的第一类型的细胞和第二类型的细胞的介电电泳运动，将第一类型的细胞与腔室中的第二类型的细胞分离，其中至少一种的介电电泳特性 的第一类型的细胞和第二类型的细胞已被修改。

    Surface Modification in a Manipulation Chamber
    2.
    发明申请
    Surface Modification in a Manipulation Chamber 审中-公开
    操纵室中的表面改性

    公开(公告)号：US20090233327A1

    公开(公告)日：2009-09-17

    申请号：US12398140

    申请日：2009-03-04

    申请人： Aldrich N.K. Lau ,  Huan L. Phan

    发明人： Aldrich N.K. Lau ,  Huan L. Phan

    IPC分类号： C12Q1/02 ,  B05D5/12 ,  B05D3/00

    CPC分类号： G01N27/305 ,  B03C11/00 ,  C07K1/26

    摘要： A device for manipulating biological material, the device including at least one electrode and a photoconductive material configured to receive the biological material; and a light source configured to illuminate the photoconductive material so as to modulate an electric field, wherein the electric field is configured to manipulate the biological material; wherein a surface of the at least one electrode and/or the photoconductive material is modified with at least one of a carboxylic moiety, an amino moiety, a poly(ethylene glycol) moiety, a polymer of (poly(ethylene oxide) methyl ether) acrylate, a poly(2-hydroxyethyl (meth)acrylate), a poly(N-vinylpyrrolidone), a poly(N-vinylformamide), a poly(N-vinylformamide) derivative, a poly((meth)acrylamide), and a poly((meth)acrylamide) derivative. Methods for manipulating biological material are also disclosed.

    摘要翻译： 一种用于操纵生物材料的装置，该装置包括至少一个电极和被配置为容纳生物材料的光导材料; 以及光源，被配置为照亮所述光电导材料以调制电场，其中所述电场被配置为操纵所述生物材料; 其中所述至少一个电极和/或光电导材料的表面用羧基部分，氨基部分，聚（乙二醇）部分，（聚（环氧乙烷）甲基醚）的聚合物， 丙烯酸酯，聚（甲基）丙烯酸2-羟乙酯），聚（N-乙烯基吡咯烷酮），聚（N-乙烯基甲酰胺），聚（N-乙烯基甲酰胺）衍生物，聚（（甲基）丙烯酰胺） 聚（（甲基）丙烯酰胺）衍生物。 还公开了用于操作生物材料的方法。

    Porous Polymer Electrodes
    10.
    发明申请
    Porous Polymer Electrodes 审中-公开
    多孔聚合物电极

    公开(公告)号：US20100092867A1

    公开(公告)日：2010-04-15

    申请号：US12504488

    申请日：2009-07-16

    申请人： Aldrich N.K. Lau ,  Konrad Faulstich ,  Kristian M. Scaboo

    发明人： Aldrich N.K. Lau ,  Konrad Faulstich ,  Kristian M. Scaboo

    IPC分类号： H01M4/58 ,  H01M4/02

    CPC分类号： G01N27/3335

    摘要： Porous polymer electrode assemblies are useful in the detection or quantification of a variety of analytes. By preparing a porous monolith, and applying a conductive polymer to the monolith, a porous matrix is prepared that combines favorable conductive properties, by virtue of the presence of the conductive polymer, with the porous character of the underlying monolith. The resulting porous electrode can be used for qualitative or quantitative analysis, and the capture and/or release of selected charged materials, such as nucleic acids. The pores of the electrode matrix may also be filled with nonconductive material, yielding electrodes having a plurality of discrete conductive surfaces.

    摘要翻译： 多孔聚合物电极组件可用于检测或定量各种分析物。 通过制备多孔整料并将导电聚合物施加到整料上，制备出多孔基质，其通过导电聚合物的存在与下面的整料的多孔特征结合有利的导电性能。 所得的多孔电极可用于定性或定量分析，以及所选择的带电材料（例如核酸）的捕获和/或释放。 电极基体的孔也可以用非导电材料填充，产生具有多个离散导电表面的电极。