摘要:
A method to render a medical article antithrombogenic and/or anti-infective includes coextruding a base polymer with a hydrophilic laminating polymer having dispersed therein a quarternary salt complexing agent and steeping the extruded article in an aqueous solution of an antithrombogenic and/or anti-infective reagent whereby the reagent is absorbed along with water by the hydrophilic polymer and reacts with the complexing agent.
摘要:
An obturator is provided which allows for placing and withdrawing of a single catheter obturator over an extended period of time so as to allow spaced intervals of use, and non-use of a catheter while in place in the patient's skin, while at the same time doing away with cumbersome, costly and time consuming administration and maintenance of saline and heparin locks. The device feeds the obturator in place for occluding the catheter lumen, when no fluids are being administered to the patient, and then may be retracted to a position allowing fluid feed through a supply tube connection to the catheter. The device includes a coating on the obturator rod which swells in contact with aqueous fluids to seal completely the catheter lumen which coating includes heparin to prevent clotting. Moreover, the entire internal functioning arrangement remains sterile during the entire period of use, thus avoiding infection.
摘要:
Melt processable polyurethaneureas are prepared from a diisocyanate, a macroglycol, a diol chain extender and a diamine chain extender. Water may be included as a reactant, and the polymer may contain an additive such as a radiopaque material. The invention includes a one-pot bulk polymerization method for preparation of the polymers.
摘要:
An obturator is provided which allows for placing and withdrawing of a single catheter obturator over an extended period of time so as to allow speed intervals of use, and non-use of a catheter while in place in the patient's skin, while at the same time doing away with cumbersome, costly and time consuming administration and maintenance of saline and heparin locks. The device feeds the obturator in place for occluding the catheter lumen, when no fluids are being administered to the patient, and then may be retracted to a position allowing fluid feed through a supply tube connection to the catheter. The device includes a coating on the obturator rod which swells in contact with aqueous fluids to seal completely the catheter lumen which coating includes heparin to prevent clotting. Moreover, the entire internal functioning arrangement remains sterile during the entire period of use, thus avoiding infection.
摘要:
A medical needle shield apparatus is provided that includes a needle hub (104) having an outer needle cannula (103) extending therefrom. An inner needle (106) is disposed for slidable movement with the outer needle cannula (103). At least one shield (101) is extensible from a retracted position to an extended position to enclose a distal end of the inner needle (101). The shield (101) includes a binding member (105) disposed within the shield (101) and defines binding surfaces (122) that form an aperture (138) configured for slidable receipt of the inner needle (106). The binding member (105) includes a binding member reset surface (107) aligned with a reset surface (108) for engagement therewith to allow reuse of a shielded needle apparatus.
摘要:
Caps can be used to cover and disinfect a male protrusion portion of a medical connector. Some caps can create a seal with the male protrusion to prevent antiseptic from entering a lumen the protrusion. A biasing element can aid in creating or maintaining the seal.
摘要:
The invention generally relates to a needle assembly of the kind having a needle, an elongate blunting device, a shifting member, and a flash chamber. The needle is of the kind that has a needle proximal end, a sharp needle distal end and a needle cannula extending therethrough. The elongate blunting device is at least partially located within the needle cannula. The elongate blunting device is of the kind that has a blunting device proximal end, a blunting device distal end, and a blunting device blood flow passage therethrough through which blood can flow from the blunting device distal end to the blunting device proximal end. The shifting member can be actuated to move relative to the needle and, upon movement relative to the needle, causes movement to the elongate blunting device from a retracted position wherein the blunting device distal end is retracted into the needle cannula so that the sharp needle distal end can penetrate the body, to an extended position wherein the blunting device distal end extends out of the needle cannula so as to prevent the sharp needle distal end from penetrating the body.
摘要:
Melt processable polyurethaneureas are prepared from a diisocyanate, a polyglycol, a diol chain extender and an amine terminated polyether. Water may be included as a reactant, and the polymer may contain an additive such as a radiopaque material and a coating of an antithrombogenic agent or an antimicrobial agent. The invention includes a one-pot bulk polymerization method for preparation of the polymers.
摘要:
A catheter of a thermoplastic elastomeric hydrophilic polyurethane is coated on at least the outside surface with a hydrophobic polymer and expands to a larger lumen size in about 3 to 15 minutes when contacted with an aqueous liquid. The hydrophilic polyurethane may be synthesized by one-shot bulk polymerization, and may be melt extruded into a base tubing and dip coated with the hydrophobic polymer, or the hydrophilic polyurethane and hydrophobic polymer may be coextruded. The catheter may have multiple lumens and may include an antithrombogenic agent, antiinfective agent and radiopaque agent.
摘要:
A leach resistant composition includes a quaternary ammonium complex of heparin and a silicone. A method for applying a coating of the composition to a surface of a medical article is within the purview of the present invention. Medical articles having surfaces which are both lubricious and antithrombogenic, are produced in accordance with the method hereof.