公开(公告)号：US08364231B2

公开(公告)日：2013-01-29

申请号：US12055114

申请日：2008-03-25

申请人： Apurv Ullas Kamath ,  Jacob S. Leach ,  Ying Li ,  Daiting Rong ,  Sean Saint ,  Peter C. Simpson ,  Mark Brister

发明人： Apurv Ullas Kamath ,  Jacob S. Leach ,  Ying Li ,  Daiting Rong ,  Sean Saint ,  Peter C. Simpson ,  Mark Brister

IPC分类号： A61B5/05

CPC分类号： A61B5/14532 ,  A61B5/145 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/412 ,  A61B5/6848 ,  A61B5/6849 ,  A61B5/6852 ,  A61B5/7235 ,  A61B2560/0223 ,  A61M5/14 ,  A61M5/16804 ,  A61M25/007 ,  A61M2230/201 ,  C12Q1/001 ,  C12Q1/006 ,  G06F19/3468 ,  G16H40/40 ,  Y02A90/26

摘要： Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

公开(公告)号：US20090018424A1

公开(公告)日：2009-01-15

申请号：US12055114

申请日：2008-03-25

申请人： Apurv Ullas Kamath ,  Jacob S. Leach ,  Ying Li ,  Daiting Rong ,  Sean Saint ,  Peter C. Simpson ,  Mark Brister

发明人： Apurv Ullas Kamath ,  Jacob S. Leach ,  Ying Li ,  Daiting Rong ,  Sean Saint ,  Peter C. Simpson ,  Mark Brister

IPC分类号： A61B5/1473

CPC分类号： A61B5/14532 ,  A61B5/145 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/412 ,  A61B5/6848 ,  A61B5/6849 ,  A61B5/6852 ,  A61B5/7235 ,  A61B2560/0223 ,  A61M5/14 ,  A61M5/16804 ,  A61M25/007 ,  A61M2230/201 ,  C12Q1/001 ,  C12Q1/006 ,  G06F19/3468 ,  G16H40/40 ,  Y02A90/26

摘要： Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

公开(公告)号：US20120078071A1

公开(公告)日：2012-03-29

申请号：US13247856

申请日：2011-09-28

申请人： Sebastian Bohm ,  Mark Dervaes ,  Eric Johnson ,  Apurv Ullas Kamath ,  Shawn Larvenz ,  Jacob S. Leach ,  Phong Lieu ,  Aarthi Mahalingam ,  Tom Miller ,  Paul V. Neale ,  Jack Pryor ,  Thomas A. Peyser ,  Daiting Rong ,  Kenneth San Vicente ,  Mohammad Ali Shariati ,  Peter C. Simpson ,  Matthew Wightlin

发明人： Sebastian Bohm ,  Mark Dervaes ,  Eric Johnson ,  Apurv Ullas Kamath ,  Shawn Larvenz ,  Jacob S. Leach ,  Phong Lieu ,  Aarthi Mahalingam ,  Tom Miller ,  Paul V. Neale ,  Jack Pryor ,  Thomas A. Peyser ,  Daiting Rong ,  Kenneth San Vicente ,  Mohammad Ali Shariati ,  Peter C. Simpson ,  Matthew Wightlin

IPC分类号： A61B5/145

CPC分类号： A61B5/14532 ,  A61B5/14507 ,  A61B5/1451 ,  A61B2560/0209 ,  A61B2560/0214 ,  A61B2562/02 ,  G06F1/3203

摘要： Systems and methods for processing, transmitting, and displaying data received from a continuous analyte (e.g., glucose) sensor are provided. A sensor system can comprise a sensor electronics module that includes power saving features, e.g., a low power measurement circuit that can be switched between a measurement mode and a low power mode, wherein charging circuitry continues to apply power to electrodes of a sensor during the low power mode. The sensor electronics module can be switched between a low power storage mode and a higher power operational mode via a switch, e.g., a reed switch or optical switch. A validation routine can be implemented to ensure an interrupt signal sent from the switch is valid. The sensor can be physically connected to the sensor electronics module in direct wireless communication with a plurality of different display devices.

摘要翻译： 提供了用于处理，传输和显示从连续分析物（例如，葡萄糖）传感器接收的数据的系统和方法。 传感器系统可以包括传感器电子模块，其包括省电功能，例如可以在测量模式和低功率模式之间切换的低功率测量电路，其中充电电路在该期间继续向传感器的电极施加功率 低功耗模式。 传感器电子模块可以通过诸如簧片开关或光开关的开关在低功率存储模式和较高功率操作模式之间切换。 可以实现验证程序，以确保从交换机发送的中断信号有效。 传感器可以与多个不同的显示设备直接无线通信，物理地连接到传感器电子模块。

公开(公告)号：US10231653B2

公开(公告)日：2019-03-19

申请号：US13247856

申请日：2011-09-28

申请人： Sebastian Bohm ,  Mark Dervaes ,  Eric Johnson ,  Apurv Ullas Kamath ,  Shawn Larvenz ,  Jacob S. Leach ,  Phong Lieu ,  Aarthi Mahalingam ,  Tom Miller ,  Paul V. Neale ,  Jack Pryor ,  Thomas A. Peyser ,  Daiting Rong ,  Kenneth San Vicente ,  Mohammad Ali Shariati ,  Peter C. Simpson ,  Matthew Wightlin

发明人： Sebastian Bohm ,  Mark Dervaes ,  Eric Johnson ,  Apurv Ullas Kamath ,  Shawn Larvenz ,  Jacob S. Leach ,  Phong Lieu ,  Aarthi Mahalingam ,  Tom Miller ,  Paul V. Neale ,  Jack Pryor ,  Thomas A. Peyser ,  Daiting Rong ,  Kenneth San Vicente ,  Mohammad Ali Shariati ,  Peter C. Simpson ,  Matthew Wightlin

IPC分类号： G06F1/32 ,  A61B5/145 ,  G06F1/3203

摘要： Systems and methods for processing, transmitting, and displaying data received from a continuous analyte (e.g., glucose) sensor are provided. A sensor system can comprise a sensor electronics module that includes power saving features, e.g., a low power measurement circuit that can be switched between a measurement mode and a low power mode, wherein charging circuitry continues to apply power to electrodes of a sensor during the low power mode. The sensor electronics module can be switched between a low power storage mode and a higher power operational mode via a switch, e.g., a reed switch or optical switch. A validation routine can be implemented to ensure an interrupt signal sent from the switch is valid. The sensor can be physically connected to the sensor electronics module in direct wireless communication with a plurality of different display devices.

公开(公告)号：US09801575B2

公开(公告)日：2017-10-31

申请号：US13446848

申请日：2012-04-13

申请人： Sebastian Bohm ,  Daiting Rong ,  Peter C. Simpson

发明人： Sebastian Bohm ,  Daiting Rong ,  Peter C. Simpson

IPC分类号： A61B5/1495 ,  G01N37/00 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

CPC分类号： A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7257 ,  A61B5/7267 ,  A61B2560/0276 ,  G01D18/00 ,  G01N27/026 ,  G01N27/3274 ,  G01N33/49

摘要： Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20120265035A1

公开(公告)日：2012-10-18

申请号：US13446848

申请日：2012-04-13

申请人： Sebastian Bohm ,  Daiting Rong ,  Peter C. Simpson

发明人： Sebastian Bohm ,  Daiting Rong ,  Peter C. Simpson

IPC分类号： A61B5/1495 ,  G01N37/00

CPC分类号： A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7257 ,  A61B5/7267 ,  A61B2560/0276 ,  G01D18/00 ,  G01N27/026 ,  G01N27/3274 ,  G01N33/49

摘要： Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20120265037A1

公开(公告)日：2012-10-18

申请号：US13446983

申请日：2012-04-13

申请人： Sebastian Bohm ,  Daiting Rong ,  Peter C. Simpson

发明人： Sebastian Bohm ,  Daiting Rong ,  Peter C. Simpson

IPC分类号： A61B5/145

CPC分类号： A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7257 ,  A61B5/7267 ,  A61B2560/0276 ,  G01D18/00 ,  G01N27/026 ,  G01N27/3274 ,  G01N33/49

摘要： Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20120262298A1

公开(公告)日：2012-10-18

申请号：US13446977

申请日：2012-04-13

申请人： Sebastian Bohm ,  Daiting Rong ,  Peter C. Simpson

发明人： Sebastian Bohm ,  Daiting Rong ,  Peter C. Simpson

IPC分类号： G01R27/02 ,  G08B21/18 ,  G01N25/00 ,  G08B21/20 ,  G01R31/00 ,  G06F19/00

CPC分类号： A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7257 ,  A61B5/7267 ,  A61B2560/0276 ,  G01D18/00 ,  G01N27/026 ,  G01N27/3274 ,  G01N33/49

摘要： Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US09848809B2

公开(公告)日：2017-12-26

申请号：US13446983

申请日：2012-04-13

申请人： Sebastian Bohm ,  Daiting Rong ,  Peter C. Simpson

发明人： Sebastian Bohm ,  Daiting Rong ,  Peter C. Simpson

IPC分类号： A61B5/1495 ,  A61B5/1486 ,  A61B5/1473 ,  G01D18/00 ,  G01N33/49 ,  G01N27/327 ,  A61B5/145 ,  A61B5/00 ,  G01N27/02

CPC分类号： A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7257 ,  A61B5/7267 ,  A61B2560/0276 ,  G01D18/00 ,  G01N27/026 ,  G01N27/3274 ,  G01N33/49

摘要： Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US09149220B2

公开(公告)日：2015-10-06

申请号：US13446977

申请日：2012-04-13

申请人： Sebastian Bohm ,  Daiting Rong ,  Peter C. Simpson

发明人： Sebastian Bohm ,  Daiting Rong ,  Peter C. Simpson

IPC分类号： G08B21/00 ,  A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00

CPC分类号： A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7257 ,  A61B5/7267 ,  A61B2560/0276 ,  G01D18/00 ,  G01N27/026 ,  G01N27/3274 ,  G01N33/49

摘要： Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

摘要翻译： 提供了用于处理传感器数据和自校准的系统和方法。 在一些实施例中，提供了能够基于初始灵敏度来校准连续分析物传感器，然后在不使用或减少使用参考测量的情况下连续执行自校准的系统和方法。 在某些实施例中，通过应用作为某些参数的函数的估计算法来确定分析物传感器的灵敏度。 本文还描述了使用刺激信号来确定分析物传感器的性质的系统和方法。 传感器属性可用于补偿传感器数据的灵敏度漂移，或确定与传感器相关的其他属性，如温度，传感器膜损坏，传感器电子设备中的水分进入以及缩放因子。