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公开(公告)号：US5513169A
公开(公告)日：1996-04-30
申请号：US346423
申请日：1994-11-29
IPC分类号： G06F1/00 , G06F21/00 , G06K1/12 , G06K19/14 , G11B7/0037 , G11B7/005 , G11B7/24 , G11B7/26 , G11B20/00 , G11B23/28 , G11B23/36 , G11B23/38 , G11B27/10 , G11B27/24 , G11B7/00
CPC分类号： G11B20/00326 , G06F21/00 , G06K1/126 , G06K19/14 , G11B20/00086 , G11B20/00115 , G11B20/00123 , G11B20/0021 , G11B20/00246 , G11B20/0026 , G11B20/00557 , G11B20/00695 , G11B20/00876 , G11B20/00927 , G11B23/281 , G11B23/284 , G11B23/36 , G11B23/38 , G11B27/105 , G11B27/24 , G11B7/005 , G11B7/24 , G11B7/26 , G11B7/0037
摘要： A machine-readable serial number is formed on a CD-ROM by using a laser to selectively remove a reflective layer from the CD-ROM, Removal of the reflective layer creates defects in addressable information storage locations on the CD-ROM, The serial number is read by detecting the defects, The serial number is used in a software distribution system in which many different software programs are distributed on a single CD-ROM and an access code based on the desired software program and the serial number of a particular CD-ROM is used to "unlock" the desired program on the particular CD-ROM,
摘要翻译： 通过使用激光器从CD-ROM中选择性地去除反射层，在CD-ROM上形成机器可读序列号，去除反射层在CD-ROM上的可寻址信息存储位置中产生缺陷。序列号 通过检测缺陷进行读取。序列号用于软件分发系统中，其中许多不同的软件程序分布在单个CD-ROM上，并且基于所需软件程序的访问代码和特定CD- ROM用于“解锁”特定CD-ROM上所需的程序，
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公开(公告)号：US5400319A
公开(公告)日：1995-03-21
申请号：US132709
申请日：1993-10-06
IPC分类号： G06F1/00 , G06F21/00 , G06K1/12 , G06K19/14 , G11B7/0037 , G11B7/005 , G11B7/24 , G11B7/26 , G11B20/00 , G11B23/28 , G11B23/36 , G11B23/38 , G11B27/10 , G11B27/24 , G11B23/30
CPC分类号： G11B20/00326 , G06F21/00 , G06K1/126 , G06K19/14 , G11B20/00086 , G11B20/00115 , G11B20/00123 , G11B20/0021 , G11B20/00246 , G11B20/0026 , G11B20/00557 , G11B20/00695 , G11B20/00876 , G11B20/00927 , G11B23/281 , G11B23/284 , G11B23/36 , G11B23/38 , G11B27/105 , G11B27/24 , G11B7/005 , G11B7/24 , G11B7/26 , G11B7/0037
摘要： A machine-readable serial number is formed on a CD-ROM by using a laser to selectively remove a reflective layer from the CD-ROM. Removal of the reflective layer creates defects in addressable information storage locations on the CD-ROM. The serial number is read by detecting the defects. The serial number is used in a software distribution system in which many different software programs are distributed on a single CD-ROM and an access code based on the desired software program and the serial number of a particular CD-ROM is used to "unlock" the desired program on the particular CD-ROM.
摘要翻译： 在CD-ROM上通过使用激光器从CD-ROM中选择性地去除反射层形成机器可读序列号。 去除反射层在CD-ROM上的可寻址信息存储位置产生缺陷。 通过检测缺陷读取序列号。 该序列号用于软件分发系统中，其中许多不同的软件程序分布在单个CD-ROM上，并且基于所需的软件程序的访问代码，并且使用特定CD-ROM的序列号来“解锁” 在特定CD-ROM上的所需程序。
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公开(公告)号：US5930215A
公开(公告)日：1999-07-27
申请号：US21673
申请日：1998-02-10
IPC分类号： G06F1/00 , G06F21/00 , G06K1/12 , G06K19/14 , G11B7/0037 , G11B7/005 , G11B7/24 , G11B7/26 , G11B20/00 , G11B23/28 , G11B23/36 , G11B23/38 , G11B27/10 , G11B27/24 , G11B7/00
CPC分类号： G11B20/00326 , G06F21/00 , G06K1/126 , G06K19/14 , G11B20/00086 , G11B20/00115 , G11B20/00123 , G11B20/0021 , G11B20/00246 , G11B20/0026 , G11B20/00557 , G11B20/00695 , G11B20/00876 , G11B20/00927 , G11B23/281 , G11B23/284 , G11B23/36 , G11B23/38 , G11B27/105 , G11B27/24 , G11B7/005 , G11B7/24 , G11B7/26 , G11B7/0037
摘要： A machine-readable serial number is formed on a CD-ROM by using a laser to selectively remove a reflective layer from the CD-ROM. Removal of the reflective layer creates defects in addressable information storage locations on the CD-ROM. The serial number is read by detecting the defects. The serial number is used in a software distribution system in which many different software programs are distributed on a single CD-ROM and an access code based on the desired software program and the serial number of a particular CD-ROM is used to "unlock" the desired program on the particular CD-ROM.
摘要翻译： 在CD-ROM上通过使用激光器从CD-ROM中选择性地去除反射层形成机器可读序列号。 去除反射层在CD-ROM上的可寻址信息存储位置产生缺陷。 通过检测缺陷读取序列号。 该序列号用于软件分发系统中，其中许多不同的软件程序分布在单个CD-ROM上，并且基于所需的软件程序的访问代码，并且使用特定CD-ROM的序列号来“解锁” 在特定CD-ROM上的所需程序。
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公开(公告)号：US5541904A
公开(公告)日：1996-07-30
申请号：US458476
申请日：1995-06-02
IPC分类号： G06F1/00 , G06F21/00 , G06K1/12 , G06K19/14 , G11B7/0037 , G11B7/005 , G11B7/24 , G11B7/26 , G11B20/00 , G11B23/28 , G11B23/36 , G11B23/38 , G11B27/10 , G11B27/24 , G11B7/00
CPC分类号： G11B20/00326 , G06F21/00 , G06K1/126 , G06K19/14 , G11B20/00086 , G11B20/00115 , G11B20/00123 , G11B20/0021 , G11B20/00246 , G11B20/0026 , G11B20/00557 , G11B20/00695 , G11B20/00876 , G11B20/00927 , G11B23/281 , G11B23/284 , G11B23/36 , G11B23/38 , G11B27/105 , G11B27/24 , G11B7/005 , G11B7/24 , G11B7/26 , G11B7/0037
摘要： A machine-readable serial number is formed on a CD-ROM by using a laser to selectively remove a reflective layer from the CD-ROM. Removal of the reflective layer creates defects in addressable information storage locations on the CD-ROM. The serial number is read by detecting the defects. The serial number is used in a software distribution system in which many different software programs are distributed on a single CD-ROM and an access code based on the desired software program and the serial number of a particular CD-ROM is used to "unlock" the desired program on the particular CD-ROM.
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公开(公告)号：US5805549A
公开(公告)日：1998-09-08
申请号：US626359
申请日：1996-04-02
IPC分类号： G06F1/00 , G06F21/00 , G06K1/12 , G06K19/14 , G11B7/0037 , G11B7/005 , G11B7/24 , G11B7/26 , G11B20/00 , G11B23/28 , G11B23/36 , G11B23/38 , G11B27/10 , G11B27/24 , G11B27/19
CPC分类号： G11B20/00326 , G06F21/00 , G06K1/126 , G06K19/14 , G11B20/00086 , G11B20/00115 , G11B20/00123 , G11B20/0021 , G11B20/00246 , G11B20/0026 , G11B20/00557 , G11B20/00695 , G11B20/00876 , G11B20/00927 , G11B23/281 , G11B23/284 , G11B23/36 , G11B23/38 , G11B27/105 , G11B27/24 , G11B7/005 , G11B7/24 , G11B7/26 , G11B7/0037
摘要： A machine-readable serial number is formed on a CD-ROM by using a laser to selectively remove a reflective layer from the CD-ROM. Removal of the reflective layer creates defects in addressable information storage locations on the CD-ROM. The serial number is read by detecting the defects. The serial number is used in a software distribution system in which many different software programs are distributed on a single CD-ROM and an access code based on the desired software program and the serial number of a particular CD-ROM is used to "unlock" the desired program on the particular CD-ROM.
摘要翻译： 在CD-ROM上通过使用激光器从CD-ROM中选择性地去除反射层形成机器可读序列号。 去除反射层在CD-ROM上的可寻址信息存储位置产生缺陷。 通过检测缺陷读取序列号。 该序列号用于软件分发系统中，其中许多不同的软件程序分布在单个CD-ROM上，并且基于所需的软件程序的访问代码，并且使用特定CD-ROM的序列号来“解锁” 在特定CD-ROM上的所需程序。
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公开(公告)号：US09102614B2
公开(公告)日：2015-08-11
申请号：US13806067
申请日：2011-07-01
申请人： Kerim Babaoglu , Elizabeth Bacon , Kyla Bjornson , Hongyan Guo , Randall L. Halcomb , Paul Hrvatin , John O. Link , Hongtao Liu , Ryan Mcfadden , Michael L. Mitchell , Paul Roethle , James Taylor , James D. Trenkle , Randall W. Vivian , Lianhong Xu
发明人： Kerim Babaoglu , Elizabeth Bacon , Kyla Bjornson , Hongyan Guo , Randall L. Halcomb , Paul Hrvatin , John O. Link , Hongtao Liu , Ryan Mcfadden , Michael L. Mitchell , Paul Roethle , James Taylor , James D. Trenkle , Randall W. Vivian , Lianhong Xu
IPC分类号： C07D295/073 , C07D295/155 , C07D493/04 , C07D311/20 , C07D311/58 , C07D239/34 , C07D239/36 , C07D231/12 , C07D213/64 , C07D213/73 , C07D213/65 , C07D205/04 , C07D215/14 , C07C59/64 , C07D211/48 , C07D215/04 , C07D233/58 , C07D241/12 , C07D309/10 , C07D491/06 , C07C229/34 , C07C233/47 , C07C255/57 , C07C271/22 , C07C311/16 , C07D239/26 , C07D239/42 , C07D487/04
CPC分类号： C07C59/64 , C07C229/34 , C07C233/47 , C07C255/57 , C07C271/22 , C07C311/16 , C07D205/04 , C07D211/48 , C07D213/64 , C07D213/65 , C07D213/73 , C07D215/04 , C07D215/14 , C07D231/12 , C07D233/58 , C07D239/26 , C07D239/34 , C07D239/36 , C07D239/42 , C07D241/12 , C07D295/073 , C07D295/155 , C07D309/10 , C07D311/20 , C07D311/58 , C07D487/04 , C07D491/06 , C07D493/04
摘要： The invention provides compounds of formula (I): or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula I and therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal using compounds of formula (I).
摘要翻译： 本发明提供了本文所述的式（I）化合物或其盐。 本发明还提供了包含式I化合物的药物组合物，制备式（I）化合物的方法，用于制备式I化合物的中间体和治疗HIV病毒增殖的治疗方法，治疗AIDS或延迟 使用式（I）化合物的哺乳动物中的AIDS或ARC症状。
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公开(公告)号：US20140249074A1
公开(公告)日：2014-09-04
申请号：US14280478
申请日：2014-05-16
申请人： Elizabeth M. Bacon , Eda Canales , Aesop Cho , Jeromy J. Cottell , Manoj C. Desai , Michael Graupe , Hongyan Guo , Randall L. Halcomb , Darryl Kato , Choung U. Kim , Thorsten A. Kirschberg , Evan S. Krygowski , Scott E. Lazerwith , John O. Link , Hongtao Liu , Qi Liu , Richard L. Mackman , Michael L. Mitchell , Jay P. Parrish , Hyung-Jung Pyun , Joseph H. Saugier , Scott D. Schroeder , Jianyu Sun , James G. Taylor , James D. Trenkle , Winston C. Tse , Randall W. Vivian , William J. Watkins , Lianhong Xu
发明人： Elizabeth M. Bacon , Eda Canales , Aesop Cho , Jeromy J. Cottell , Manoj C. Desai , Michael Graupe , Hongyan Guo , Randall L. Halcomb , Darryl Kato , Choung U. Kim , Thorsten A. Kirschberg , Evan S. Krygowski , Scott E. Lazerwith , John O. Link , Hongtao Liu , Qi Liu , Richard L. Mackman , Michael L. Mitchell , Jay P. Parrish , Hyung-Jung Pyun , Joseph H. Saugier , Scott D. Schroeder , Jianyu Sun , James G. Taylor , James D. Trenkle , Winston C. Tse , Randall W. Vivian , William J. Watkins , Lianhong Xu
IPC分类号： A61K31/4184 , A61K45/06
CPC分类号： C07D403/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/427 , A61K31/435 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K31/5415 , A61K31/55 , A61K45/06 , A61P31/12 , C07D207/16 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D491/113 , C07D495/04 , C07F5/025
摘要： The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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公开(公告)号：US20140045818A1
公开(公告)日：2014-02-13
申请号：US14112473
申请日：2012-04-20
申请人： Michael L. Mitchell , Paul A. Roethle , Lianhong Xu , Hong Yang , Ryan McFadden , Kerim Babaoglu
发明人： Michael L. Mitchell , Paul A. Roethle , Lianhong Xu , Hong Yang , Ryan McFadden , Kerim Babaoglu
IPC分类号： C07D491/052 , A61K45/06 , C07D277/82 , A61K31/4741 , C07D277/64 , A61K31/428
CPC分类号： C07D491/06 , A61K9/0019 , A61K9/12 , A61K9/20 , A61K9/48 , A61K31/428 , A61K31/4741 , A61K45/06 , C07D277/62 , C07D277/64 , C07D277/82 , C07D417/04 , C07D417/10 , C07D491/052
摘要： The invention provides compounds of formula I: or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal using compounds of formula I.
摘要翻译： 本发明提供了本文所述的式I化合物或其盐。 本发明还提供了包含式I化合物的药物组合物，制备式I化合物的方法，可用于制备式I化合物的中间体和用于治疗HIV病毒增殖，治疗AIDS或延迟AIDS发作的治疗方法或 哺乳动物使用式I化合物的ARC症状。
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9.发明授权2,4,6-trisubstituted pyrido(3,2-d)pyrimidines useful for treating viral infections 有权2,4,6-三取代吡啶并（3,2-d）嘧啶可用于治疗病毒感染公开(公告)号：US08536187B2
公开(公告)日：2013-09-17
申请号：US12996110
申请日：2009-07-01
申请人： Eda Canales , Lee S. Chong , Michael O' Neil Hanrahan Clarke , Scott E. Lazerwith , Willard Lew , Qi Liu , Michael L. Mitchell , William J. Watkins , Jennifer R. Zhang
发明人： Eda Canales , Lee S. Chong , Michael O' Neil Hanrahan Clarke , Scott E. Lazerwith , Willard Lew , Qi Liu , Michael L. Mitchell , William J. Watkins , Jennifer R. Zhang
IPC分类号： A01N43/90 , A61K31/519 , C07D487/00
CPC分类号： C07D471/04
摘要： Pyrido(3,2-d)pyrimidine derivatives represented by the structural formula (Ia): wherein, R1, R2 and R3 are defined herein, pharmaceutical acceptable addition salts, stereochemical isomeric forms, N-oxides, solvates and pro-drugs thereof, for use in the treatment of hepatitis C.
摘要翻译： 由结构式（Ia）表示的吡啶并（3,2-d）嘧啶衍生物：其中R1，R2和R3如本文所定义，药学上可接受的加成盐，立体化学异构形式，N-氧化物，溶剂化物和其前体药物， 用于治疗丙型肝炎。
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公开(公告)号：US08354421B2
公开(公告)日：2013-01-15
申请号：US12215264
申请日：2008-06-26
申请人： Gong-Xin He , Choung U. Kim , Michael L. Mitchell , Lianhong Xu
发明人： Gong-Xin He , Choung U. Kim , Michael L. Mitchell , Lianhong Xu
IPC分类号： A61K31/505 , C07F9/09 , C07D239/08
CPC分类号： C07D239/54
摘要： The invention is related to compounds of Formula (I): or a pharmaceutically acceptable salt, solvate, ester, and/or phosphonate thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.
摘要翻译： 本发明涉及式（I）化合物或其药学上可接受的盐，溶剂合物，酯和/或膦酸盐，含有这些化合物的组合物，以及包括施用这些化合物的治疗方法。
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