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公开(公告)号：US20240287474A1
公开(公告)日：2024-08-29
申请号：US18657101
申请日：2024-05-07
Applicant: Codexis, Inc.
Inventor： Christopher Micklitsch , Oscar Alvizo , Jovana Nazor , Harvinder Chagger Maniar , Mikayla Jianghongxia Krawczyk , Margie Tabuga Borra-Garske , Nandhitha Subramanian , Anna Fryszkowska , Nicholas M. Marshall , Agustina Rodriguez-Granillo , Deeptak Verma , Dewan Andrews
CPC classification number: C12N9/0006 , C12N15/52 , C12N9/001 , C12P21/02 , C12Y101/03009
Abstract: The present invention provides engineered galactose oxidase (GOase) enzymes, polypeptides having GOase activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing GOase enzymes are also provided. The present invention further provides compositions comprising the GOase enzymes and methods of using the engineered GOase enzymes. The present invention finds particular use in the production of pharmaceutical and other compounds.
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公开(公告)号：US12012620B2
公开(公告)日：2024-06-18
申请号：US17635163
申请日：2020-09-03
Applicant: Codexis, Inc.
Inventor： Da Duan , Auric Anthony Sowell-Kantz , Aksiniya Lyubenova Petkova , Jovana Nazor , Nandhitha Subramanian , Oscar Alvizo
IPC: C12N9/08
CPC classification number: C12N9/0065
Abstract: The present invention provides engineered peroxidase enzymes, polypeptides having peroxidase activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing peroxidase enzymes are also provided. The present invention further provides compositions comprising the peroxidase enzymes and methods of using the engineered peroxidase enzymes. The present invention finds particular use in the production of pharmaceutical and other compounds.
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公开(公告)号：US20230183790A1
公开(公告)日：2023-06-15
申请号：US18046893
申请日：2022-10-14
Applicant: Codexis, Inc.
Inventor： Ericka Bermudez , David Elgart , Mathew G. Miller , Jovana Nazor , Zhe Rui , Nandhitha Subramanian
IPC: C12Q1/6848 , C12N9/12 , C12Q1/6851
CPC classification number: C12Q1/6848 , C12N9/1276 , C12Y207/07049 , C12Q1/6851
Abstract: The present disclosure relates to recombinant reverse transcriptase polypeptides and compositions thereof, as well as polynucleotides encoding the recombinant reverse transcriptase polypeptides. The disclosure also provides methods for using the recombinant reverse transcriptase polypeptides and compositions thereof for diagnostic and as molecular biological tools.
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公开(公告)号：US11034948B2
公开(公告)日：2021-06-15
申请号：US16460062
申请日：2019-07-02
Applicant: Codexis, Inc.
Inventor： Scott J. Novick , Xiang Yi , Nikki Dellas , Oscar Alvizo , Jovana Nazor , Da Duan , Vesna Mitchell , Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian , Jeffrey C. Moore , Mark Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Grant Murphy , Nicholas M. Marshall , Jay Russell , Keith A. Canada
Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US10889806B2
公开(公告)日：2021-01-12
申请号：US16460147
申请日：2019-07-02
Applicant: Codexis, Inc.
Inventor： Margie Tabuga Borra-Garske , Oscar Alvizo , Lillian Jasmine Miller , Jesse B. Slaton , Aksiniya Lyubenova Petkova , Nandhitha Subramanian , Joshua Kolev , Anna Fryszkowska , Agustina Rodriguez-Granillo , Grant Murphy
IPC: C12N9/12
Abstract: The present invention provides engineered pantothenate kinase (PanK) enzymes, polypeptides having PanK activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PanK enzymes are also provided. The present invention further provides compositions comprising the PanK enzymes and methods of using the engineered PanK enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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Patent Agency Ranking
公开(公告)号：US20240301367A1
公开(公告)日：2024-09-12
申请号：US18655701
申请日：2024-05-06
Applicant: Codexis, Inc.
Inventor： Da Duan , Auric Anthony Sowell-Kantz , Aksiniya Lyubenova Petkova , Jovana Nazor , Nandhitha Subramanian , Oscar Alvizo
IPC: C12N9/08
CPC classification number: C12N9/0065
Abstract: The present invention provides engineered peroxidase enzymes, polypeptides having peroxidase activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing peroxidase enzymes are also provided. The present invention further provides compositions comprising the peroxidase enzymes and methods of using the engineered peroxidase enzymes. The present invention finds particular use in the production of pharmaceutical and other compounds.
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公开(公告)号：US20230374470A1
公开(公告)日：2023-11-23
申请号：US18247863
申请日：2021-10-01
Applicant: Codexis, Inc.
Inventor： Margie Tabuga Borra-Garske , Jovana Nazor , Nandhitha Subramanian , Oscar Alvizo , Anna Fryszkowska
CPC classification number: C12N9/0006 , C12N15/70 , C12Y101/03009
Abstract: The present invention provides engineered galactose oxidase (GOase) enzymes, polypeptides having GOase activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing GOase enzymes are also provided. The present invention further provides compositions comprising the GOase enzymes and methods of using the engineered GOase enzymes. The present invention finds particular use in the production of pharmaceutical and other compounds.
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公开(公告)号：US11795445B2
公开(公告)日：2023-10-24
申请号：US17316165
申请日：2021-05-10
Applicant: Codexis, Inc.
Inventor： Scott J. Novick , Xiang Yi , Nikki Dellas , Oscar Alvizo , Jovana Nazor , Da Duan , Vesna Mitchell , Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian , Jeffrey C. Moore , Mark Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Grant S. Murphy , Nicholas Marshall , Jay Russell , Keith A. Canada
CPC classification number: C12N9/90 , C12N15/52 , C12N15/74 , C12N15/815 , C12Y504/02007
Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US20220243183A1
公开(公告)日：2022-08-04
申请号：US17617533
申请日：2020-06-30
Applicant: Codexis, Inc.
Inventor： Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian
Abstract: The present invention provides engineered sucrose phosphorylase (SP) enzymes, polypeptides having SP activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing SP enzymes are also provided. The present invention further provides compositions comprising the SP enzymes and methods of using the engineered SP enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US20210309977A1
公开(公告)日：2021-10-07
申请号：US17345404
申请日：2021-06-11
Applicant: Codexis, Inc.
Inventor： Mathew G. Miller , Vesna Mitchell , Jovana Nazor , Donald S. Baskerville , Nikki Dellas , David Elgart , Jonathan Vroom , Sandy M. Gomes , Nandhitha Subramanian , Ericka Bermudez
IPC: C12N9/12
Abstract: The present invention provides engineered DNA polymerase polypeptides and compositions thereof, as well as polynucleotides encoding the engineered DNA polymerase polypeptides. The invention also provides methods for use of the compositions comprising the engineered DNA polymerase polypeptides for diagnostic and other purposes.
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