摘要:
A method for making a microstructure includes: providing a film (100) on a release liner (110); feeding the film through a cutting plotter (10); cutting the film with a knife blade (34) of the cutting plotter to form a microstructure pattern; peeling the microstructure pattern from the release liner; and transferring the microstructure pattern to a substrate (170). The cutting plotter for making microstructures includes a knife head with a knife blade disposed adjacent a feed mechanism (20), a motor (42) and control system coupled to the knife head for selectively moving the knife head in relation to the film, and the control system and the knife head having an addressable positioning resolution less than approximately 10 μm.
摘要:
In at least one embodiment, a pair of components includes a tooth and adaptor for an earth-moving apparatus. The adaptor is for mounting the tooth on an earth-moving bucket, this mounting being releasable to allow replacement of the tooth when worn. The components define aligned passages through which a locking pin extends to retain the components together. The locking pin has formations for engaging formations on the first component when the pin is rotated from a free position into a locked position. The pin has an insertion recess which is aligned with the formations allowing the pin, in the free position, to be inserted into, or removed from, the aligned passages. The formations are resiliently movable to stably engage the pin when in the locked position.
摘要:
In at least one embodiment, a pair of components includes a tooth and adaptor for an earth-moving apparatus. The adaptor is for mounting the tooth on an earth-moving bucket, this mounting being releasable to allow replacement of the tooth when worn. The components define aligned passages through which a locking pin extends to retain the components together. The locking pin has formations for engaging formations on the first component when the pin is rotated from a free position into a locked position. The pin has an insertion recess which is aligned with the formations allowing the pin, in the free position, to be inserted into, or removed from, the aligned passages. The formations are resiliently movable to stably engage the pin when in the locked position.
摘要:
Disclosed is a spotter device and methods for the formation of microassays, biochips, biosensors, and cell cultures. The spotter may be used to deposit highly concentrated spots of protein or other materials on a microarray a slide, wafer, or other substrate. The spotter uses microfluidic conduits and orifices to deposit proteins, other biomolecules, or chemicals on a spot on a substrate. Each orifice is part of a fluid pathways that includes an inlet and outlet conduit. When the spotter contacts a substrate a seal is formed between the orifices and the substrate.
摘要:
Disclosed is a spotter device and methods for the formation of microassays, biochips, biosensors, and cell cultures. The spotter may be used to deposit highly concentrated spots of protein or other materials on a microarray a slide, wafer, or other substrate. The spotter uses microfluidic conduits and orifices to deposit proteins, other biomolecules, or chemicals on a spot on a substrate. Each orifice is part of a fluid pathways that includes an inlet and outlet conduit. When the spotter contacts a substrate a seal is formed between the orifices and the substrate.
摘要:
Disclosed is a spotter device and methods for the formation of microassays, biochips, biosensors, and cell cultures. The spotter may be used to deposit highly concentrated spots of protein or other materials on a microarray slide, wafer, or other surface. It may also be used to perform various chemistry steps on the same spots. The spotter increases the surface density of substances at each spot by directing a flow the desired substance (or a solution thereof) over the spot area until surface saturation is accomplished. The spotter may be loaded by well plate handling equipment. The spotter uses wells, microfluidic conduits, and orifices to deposit proteins, other biomolecules, or chemicals on a spot on a separate surface. Each orifice is connected to two wells via microconduits. When the spotter contacts a surface, a seal is formed between the orifices and the surface. The same or different substances may be flowed across each orifice. Any number of orifices may be incorporated into a spotter. The spotter is particularly useful for depositing proteins in high concentrations on a surface, since the spotter may be placed on a surface for an extended period of time.
摘要:
There is disclosed a pair of components which, in the embodiment described, are a tooth (2) and adaptor (3) for earth-moving apparatus (1). The adaptor is for mounting the tooth on an earth-moving bucket, this mounting being releasable to allow replacement of the tooth when worn. The components define aligned passages (11) through which a locking pin (12) extends to retain the components together. The locking pin has formations (22) for engaging formations (20) on the first component when the pin is rotated from a free position into a locked position. The pin has an insertion recess (27) which is aligned with the formations (20) allowing the pin, in the free position, to be inserted into, or removed from, the aligned passages. The formations (20) are resiliently movable to stably engage the pin when in the locked position.
摘要:
A pump device (10a, 10b, 10c) includes means for both transferring rotational momentum to the fluid by viscous forces, and imparting centrifugal forces to the fluid. The pump (10a, 10b) can include a wiper (44) extending partially across at least one rotatable disc surface (48, 48b, 48c) of at least one rotatable disc (52, 52b, 52c). The pump (10c) can include a rotatable shaft (150) with a hollow cavity (154) extending from one end to at least one slot (158) extending radially from the hollow cavity.