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公开(公告)号：US06021354A
公开(公告)日：2000-02-01
申请号：US224739
申请日：1998-12-31
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： A cardiac pacing lead for pacing the atria and a method of its use. The lead is provided with a mechanism for maintaining an atrial pacing electrode adjacent stimulable tissue in a patient's superior vena cava and an additional electrode locatable in the right ventricle or elsewhere when the atrial electrode is so located. One such mechanism for maintaining the atrial electrode's position may be a lead body displaying pre-formed laterally extending curves sized to span a patient's superior vena cava, with the atrial electrode located thereon.
摘要翻译： 用于起搏心房的心脏起搏线及其使用方法。 该引线设置有用于将心房起搏电极维持在患者上腔静脉中的可刺激组织旁边的机构，以及当心房电极如此定位时位于右心室或别处的附加电极。 用于维持心房电极的位置的一种这样的机构可以是引导体，其显示预先形成的横向延伸的曲线，其尺寸跨越患者的上腔静脉，心房电极位于其上。
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2.发明申请TECHNIQUES FOR PLACING MEDICAL LEADS FOR ELECTRICAL STIMULATION OF NERVE TISSUE 审中-公开用于放置用于电刺激神经组织的医用引线的技术公开(公告)号：US20090275996A1
公开(公告)日：2009-11-05
申请号：US12433770
申请日：2009-04-30
申请人： John E. Burnes , Eduardo N. Warman , Matthew D. Bonner , Avram Scheiner , Shailesh Kumar V. Musley
发明人： John E. Burnes , Eduardo N. Warman , Matthew D. Bonner , Avram Scheiner , Shailesh Kumar V. Musley
IPC分类号： A61N1/36
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.
摘要翻译： 本公开涉及用于在患者体内靠近神经组织布置医疗引线和电刺激和/或感测电极的额外的，内部的和经血管内的医疗引线放置技术。
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公开(公告)号：US5922014A
公开(公告)日：1999-07-13
申请号：US922693
申请日：1997-09-02
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： A cardiac pacing lead for pacing the atria and a method of its use. The lead is provided with a mechanism for maintaining an atrial pacing electrode adjacent stimulable tissue in a patient's superior vena cava and an additional electrode locatable in the right ventricle or elsewhere when the atrial electrode is so located. One such mechanism for maintaing the atrial electrode's position may be a lead body displaying pre-formed laterally extending curves sized to span a patient's superior vena cava, with the atrial electrode located thereon.
摘要翻译： 用于起搏心房的心脏起搏线及其使用方法。 该引线设置有用于将心房起搏电极维持在患者上腔静脉中的可刺激组织旁边的机构，以及当心房电极如此定位时位于右心室或别处的附加电极。 用于维持心房电极位置的一种这样的机构可以是引导体，其显示预先形成的横向延伸的曲线，其大小可跨过患者的上腔静脉，心房电极位于其上。
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公开(公告)号：US06201994B1
公开(公告)日：2001-03-13
申请号：US09449648
申请日：1999-11-30
IPC分类号： A61N105
CPC分类号： A61N1/056
摘要： A cardiac pacing lead for pacing the atria and a method of its use. The lead is provided with a mechanism for maintaining an atrial pacing electrode adjacent stimulable tissue in a patient's superior vena cava and an additional electrode locatable in the right ventricle or elsewhere when the atrial electrode is so located One such mechanism for maintaing the atrial electrode's position may be a lead body displaying pre-formed laterally extending curves sized to span a patient's superior vena cava, with the atrial electrode located thereon.
摘要翻译： 用于起搏心房的心脏起搏线及其使用方法。 引线设置有用于将心房起搏电极维持在邻近患者上腔静脉中的可刺激组织的位置，以及当心房电极位于其中时位于右心室或其他地方的附加电极。一种用于维持心房电极位置的机构 作为引导体，显示预先形成的横向延伸的曲线，其大小适于跨过患者的上腔静脉，心房电极位于其上。
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公开(公告)号：US07191016B2
公开(公告)日：2007-03-13
申请号：US10439201
申请日：2003-05-15
申请人： Mark T. Marshall , Teresa A. Whitman , Eduardo N. Warman , Jeffrey M. Gillberg , Matthew D. Bonner , Mark L. Brown
发明人： Mark T. Marshall , Teresa A. Whitman , Eduardo N. Warman , Jeffrey M. Gillberg , Matthew D. Bonner , Mark L. Brown
IPC分类号： A61N1/05
CPC分类号： A61N1/0573 , A61N1/0568 , A61N1/057 , A61N1/368 , A61N1/3702 , A61N2001/0585
摘要： A medical electrical lead includes a first low voltage electrode adapted for intimate contact with tissue at an implant site, in order to provide pacing stimulation, and a second low voltage electrode positioned in proximity to the first electrode, isolated from the first electrode and adapted to function in conjunction with the first electrode to provide bipolar sensing of near-field signals. A porous layer is formed over the second electrode; the porous layer allows conduction therethrough while preventing contact between the second electrode and tissue in proximity to the implant site.
摘要翻译： 医疗电引线包括适于在植入部位处与组织紧密接触的第一低电压电极，以便提供起搏刺激，以及位于第一电极附近的第二低电压电极，与第一电极隔离并且适于 与第一电极结合起来提供近场信号的双极感测。 在第二电极上形成多孔层; 多孔层允许穿过其中，同时防止在植入部位附近的第二电极和组织之间的接触。
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公开(公告)号：US08903512B2
公开(公告)日：2014-12-02
申请号：US10630547
申请日：2003-07-29
申请人： Mark T. Marshall , Teresa A. Whitman , Eduardo N. Warman , Jeffrey M. Gillberg , Matthew D. Bonner , Mark L. Brown
发明人： Mark T. Marshall , Teresa A. Whitman , Eduardo N. Warman , Jeffrey M. Gillberg , Matthew D. Bonner , Mark L. Brown
CPC分类号： A61N1/057 , A61N1/0568 , A61N1/0573 , A61N1/368 , A61N1/3702 , A61N2001/0585
摘要： An implantable electrical medical system comprises a low voltage cathode electrode assembly, including a cathode surface adapted for, intimate contact with electrically active tissue, and a low voltage anode electrode assembly, including an anode surface and a porous layer extending over the anode surface. The cathode surface and the anode surface function as a bipolar pair for pacing and the porous layer extending over the anode surface allows conduction therethrough and prevents the anode surface from contacting the electrically active tissue in order to prevent anodal stimulation.
摘要翻译： 可植入电气医疗系统包括低电压阴极电极组件，其包括适于与电活性组织紧密接触的阴极表面，以及包括在阳极表面上延伸的阳极表面和多孔层的低压阳极电极组件。 阴极表面和阳极表面用作用于起搏的双极对，并且在阳极表面上延伸的多孔层允许通过其传导，并且防止阳极表面接触电活性组织以防止阳极刺激。
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公开(公告)号：US10542887B2
公开(公告)日：2020-01-28
申请号：US13436408
申请日：2012-03-30
申请人： Shantanu Sarkar , Jodi L. Redemske , Eduardo N. Warman , Douglas A. Hettrick , Kevin T. Ousdigian
发明人： Shantanu Sarkar , Jodi L. Redemske , Eduardo N. Warman , Douglas A. Hettrick , Kevin T. Ousdigian
摘要： Techniques for transmitting diagnostic information stored in an implantable medical device (IMD) based on patient hospitalization are described. For example, the IMD may transmit higher resolution diagnostic information to a clinician and/or an external device during a hospitalization period to aid the clinician in evaluating heart failure treatment and when discharge is proper. This higher resolution diagnostic information may include one or more patient metrics automatically generated and transmitted by the IMD at least once every two hours. During a post-hospitalization period, the IMD may transmit lower resolution diagnostic information to a clinician that indicates a risk level of re-hospitalization. The lower resolution diagnostic information may include the risk level and/or patient metrics once a day, for example. In this manner, the IMD transmitted diagnostic information may be tailored to the specific heart failure monitoring needed by the patient.
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公开(公告)号：US08843189B2
公开(公告)日：2014-09-23
申请号：US12423487
申请日：2009-04-14
申请人： H. Toby Markowitz , Mustafa Karamanoglu , Pooja Mehta , Ioana Fleming , David A. Scanlon , Michael Kryger , Sean Campbell-Massa , Chad Giese , Steven L. Waldhauser , Shangqian Peter Zhang , Jeff Jannicke , Phillip Falkner , Don Hefner , Eduardo N. Warman , James Steeves , Rogier Receveur , Koen Michels , Olaf Eick , Vincent Larik
发明人： H. Toby Markowitz , Mustafa Karamanoglu , Pooja Mehta , Ioana Fleming , David A. Scanlon , Michael Kryger , Sean Campbell-Massa , Chad Giese , Steven L. Waldhauser , Shangqian Peter Zhang , Jeff Jannicke , Phillip Falkner , Don Hefner , Eduardo N. Warman , James Steeves , Rogier Receveur , Koen Michels , Olaf Eick , Vincent Larik
IPC分类号： A61B5/04 , A61B19/00 , A61B5/042 , A61B5/053 , A61B17/00 , A61B5/06 , A61B8/00 , A61B5/05 , A61B8/06
CPC分类号： A61B5/061 , A61B5/0422 , A61B5/04288 , A61B5/0432 , A61B5/044 , A61B5/05 , A61B5/053 , A61B5/0538 , A61B5/06 , A61B5/062 , A61B5/063 , A61B5/066 , A61B5/4836 , A61B5/742 , A61B8/06 , A61B8/4472 , A61B34/20 , A61B34/25 , A61B2017/00022 , A61B2017/00026 , A61B2017/00053 , A61B2017/00084 , A61B2017/00243 , A61B2017/00336 , A61B2017/22051 , A61B2034/105 , A61B2090/376 , A61B2090/378 , A61B2090/3983
摘要： A volume of a patient can be mapped with a system operable to identify a plurality of locations and save a plurality of locations of a mapping instrument. The mapping instrument can include one or more electrodes that can sense a voltage that can be correlated to a three dimensional location of the electrode at the time of the sensing or measurement. Therefore, a map of a volume can be determined based upon the sensing of the plurality of points without the use of other imaging devices. An implantable medical device can then be navigated relative to the mapping data.
摘要翻译： 可以利用可操作以识别多个位置并且存储映射仪器的多个位置的系统来映射患者体积。 映射仪器可以包括一个或多个电极，其可以感测在感测或测量时可以与电极的三维位置相关联的电压。 因此，可以基于多个点的感测而不使用其它成像装置来确定体积的映射。 然后可以相对于映射数据导航可植入医疗装置。
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9.发明授权Method and apparatus for determining tracking a virtual point defined relative to a tracked member 有权用于确定跟踪相对于被跟踪的成员定义的虚拟点的方法和装置公开(公告)号：US08340751B2
公开(公告)日：2012-12-25
申请号：US12422689
申请日：2009-04-13
申请人： H. Toby Markowitz , Mustafa Karamanoglu , Pooja Mehta , Ioana Fleming , David A. Scanlon , Michael Kryger , Sean Campbell-Massa , Chad Giese , Steven L. Waldhauser , Shangqian Peter Zhang , Jeff Jannicke , Phillip Falkner , Don Hefner , Eduardo N. Warman , James Steeves , Rogier Receveur , Koen Michels , Olaf Eick , Vincent Larik
发明人： H. Toby Markowitz , Mustafa Karamanoglu , Pooja Mehta , Ioana Fleming , David A. Scanlon , Michael Kryger , Sean Campbell-Massa , Chad Giese , Steven L. Waldhauser , Shangqian Peter Zhang , Jeff Jannicke , Phillip Falkner , Don Hefner , Eduardo N. Warman , James Steeves , Rogier Receveur , Koen Michels , Olaf Eick , Vincent Larik
IPC分类号： A61B5/042
CPC分类号： A61B5/0422 , A61B5/0215 , A61B5/053 , A61B5/06 , A61B5/062 , A61B5/066 , A61B5/068 , A61B6/12 , A61B34/20 , A61B2034/2046 , A61B2034/2051 , A61B2034/2072 , G06K9/00201 , G06K2209/057
摘要： An volume of a patient can be mapped with a system operable to identify a plurality of locations and save a plurality of locations of a mapping instrument. The mapping instrument can include one or more electrodes that can sense a voltage that can be correlated to a three dimensional location of the electrode at the time of the sensing or measurement. Therefore, a map of a volume can be determined based upon the sensing of the plurality of points without the use of other imaging devices. An implantable medical device can then be navigated relative to the mapping data.
摘要翻译： 可以用可操作以识别多个位置并且存储映射仪器的多个位置的系统来映射患者体积。 映射仪器可以包括一个或多个电极，其可以感测在感测或测量时可以与电极的三维位置相关联的电压。 因此，可以基于多个点的感测而不使用其它成像装置来确定体积的映射。 然后可以相对于映射数据导航可植入医疗装置。
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10.发明授权Device and method for providing atrial-synchronized ventricular pacing with selective atrial tracking 有权用于提供心房同步心室起搏和选择性心房跟踪的装置和方法公开(公告)号：US08332030B2
公开(公告)日：2012-12-11
申请号：US11115597
申请日：2005-04-27
申请人： Michael F. Hess , Eduardo N. Warman
发明人： Michael F. Hess , Eduardo N. Warman
IPC分类号： A61N1/00
CPC分类号： A61N1/3622 , A61N1/3627 , A61N1/3684
摘要： A device for delivering pacing therapy includes an atrial and ventricular leads, sensing circuitry connected to the leads for detecting depolarizations, and pulse generation circuitry for delivering ventricular pacing pulses based on sensed atrial depolarizations. The device includes control circuitry for controlling the pulse generation circuitry in a first mode in which the pulse generation circuitry delivers atrial synchronized pulses to both the right and left ventricular leads in response to each atrial depolarization sensed. In response to a detected atrial arrhythmia, the control circuitry causes the pulse generation circuitry to deliver atrial synchronized ventricular pacing pulses in response only to selected atrial depolarizations.
摘要翻译： 用于输送起搏治疗的装置包括心房和心室引线，连接到用于检测去极化的引线的感测电路以及用于基于感测的心房去极化来输送心室起搏脉冲的脉冲产生电路。 该装置包括用于在第一模式中控制脉冲发生电路的控制电路，其中脉冲发生电路响应于感测到的每个心房去极化而将心房同步脉冲输送到右心室和左心室引线。 响应于检测到的心房心律失常，控制电路使得脉冲发生电路仅响应于所选择的心房去极化来递送心房同步心室起搏脉冲。
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