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1.发明授权Fluid transport in microfluidic applications with sensors for detecting fluid presence and pressure 有权微流体应用中的流体传输，用于检测流体存在和压力的传感器公开(公告)号：US09399216B2
公开(公告)日：2016-07-26
申请号：US14144066
申请日：2013-12-30
发明人： Victor Donald Samper , Christian Friedrich Peter Rensch , Christoph Boeld , Ruben Julian Salvamoser
CPC分类号： B01L3/502746 , B01J19/004 , B01J19/0093 , B01J2219/00783 , B01J2219/0084 , B01J2219/00891 , B01J2219/00903 , B01J2219/00959 , B01J2219/00963 , B01J2219/0097 , B01J2219/00986 , B01L3/0293 , B01L2400/08 , G01F22/02 , Y10T137/0318
摘要： A method includes flowing a liquid into a channel of a microfluidic cassette filled with a gas. The channel includes an inlet section and an outlet section. The method also includes detecting the liquid, the gas, or a combination thereof at a measuring location within the inlet section. The measuring location has a first sensor that may detect a signal indicative of a presence of the liquid, the gas, or a combination thereof. The method also includes compressing the gas, determining a pressure change of the gas within the channel, and determining a volume of the liquid within the channel based on the pressure change of the gas.
摘要翻译： 一种方法包括将液体流入填充有气体的微流控盒的通道中。 通道包括入口部分和出口部分。 该方法还包括在入口部分内的测量位置检测液体，气体或其组合。 测量位置具有可以检测指示液体，气体或其组合的存在的信号的第一传感器。 该方法还包括压缩气体，确定通道内的气体的压力变化，以及基于气体的压力变化来确定通道内的液体的体积。
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公开(公告)号：US20150182963A1
公开(公告)日：2015-07-02
申请号：US14144047
申请日：2013-12-30
发明人： Victor Donald Samper , Christian Friedrich Peter Rensch , Christoph Boeld , Ruben Julian Horvath-Klein
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01J19/0093 , B01J2219/00783 , B01J2219/00873 , B01J2219/00889 , B01J2219/00894 , B01J2219/00961 , B01J2219/00963 , B01J2219/00966 , B01J2219/00986 , B01L3/523 , B01L2200/028 , B01L2200/04 , B01L2200/12 , B01L2200/16 , B01L2300/0887 , B01L2300/16 , B01L2400/0638 , B01L2400/0683 , F16K99/0015 , F16K99/003 , F16K2099/0084 , Y10T156/10
摘要： A microfluidic device for storing a reagent includes a single unit includes a first portion having a reagent storage chamber configured to hold a reagent. The device also includes a second portion having a reaction chamber configured to support the reagent during a reaction process to form a product. The device also includes a valve configured to isolate the reagent storage compartment from the reaction chamber when the valve is in a closed state.
摘要翻译： 用于存储试剂的微流体装置包括单个单元，其包括具有被配置为保持试剂的试剂储存室的第一部分。 该装置还包括具有反应室的第二部分，反应室被配置为在反应过程中支持试剂以形成产物。 该装置还包括阀，其构造成当阀处于关闭状态时将试剂储存室与反应室隔离。
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公开(公告)号：US11486773B2
公开(公告)日：2022-11-01
申请号：US16516240
申请日：2019-07-18
摘要： A sensor for sensing stress in a ferromagnetic material includes a non-magnetic substrate. The substrate has a first surface and a second surface opposite the first surface. A first coil is attached to or formed on the first surface of the substrate. The first coil is configured to induce a magnetic flux in the ferromagnetic material being driven by an alternating current (AC) signal. At least one second coil is attached to or formed on the first surface of the substrate. The at least one second coil is spaced from the first coil. In addition, the second coil is configured to detect changes in the magnetic flux induced in the ferromagnetic material.
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公开(公告)号：US20190339140A1
公开(公告)日：2019-11-07
申请号：US16516240
申请日：2019-07-18
摘要： A sensor for sensing stress in a ferromagnetic material includes a non-magnetic substrate. The substrate has a first surface and a second surface opposite the first surface. A first coil is attached to or formed on the first surface of the substrate. The first coil is configured to induce a magnetic flux in the ferromagnetic material being driven by an alternating current (AC) signal. At least one second coil is attached to or formed on the first surface of the substrate. The at least one second coil is spaced from the first coil. In addition, the second coil is configured to detect changes in the magnetic flux induced in the ferromagnetic material.
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公开(公告)号：US20140170758A1
公开(公告)日：2014-06-19
申请号：US13718252
申请日：2012-12-18
IPC分类号： G01N23/00
CPC分类号： G21G1/0005 , A61B6/037 , B01J19/004 , B01J19/0093 , B01J2219/00132 , B01J2219/00783 , B01J2219/00831 , B01J2219/00873 , B01J2219/00889 , B01L3/5027
摘要： A system and method for controlling a microfluidic handling device is presented. One embodiment of the system includes a microfluidic synthesis cassette. Further, the system includes a synthesizer unit to receive the microfluidic synthesis cassette and execute one or more synthesis runs on the received microfluidic synthesis cassette to generate one or more radioactive doses. Also, the system includes an electronic dose tracker coupled to the microfluidic synthesis cassette to indicate a level of dose activity processed in the microfluidic synthesis cassette.
摘要翻译： 提出了一种用于控制微流控处理装置的系统和方法。 该系统的一个实施例包括微流体合成盒。 此外，该系统包括用于接收微流体合成盒并在所接收的微流体合成盒上执行一个或多个合成运行以产生一个或多个放射性剂量的合成器单元。 此外，该系统包括耦合到微流体合成盒的电子剂量跟踪器，以指示在微流体合成盒中处理的剂量活性水平。
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公开(公告)号：US20140120010A1
公开(公告)日：2014-05-01
申请号：US13731347
申请日：2012-12-31
发明人： Christian Friedrich Peter Rensch , Victor Donald Samper , Christoph Boeld , Ruben Julian Horvath-Klein
IPC分类号： B01L3/00
CPC分类号： B01L3/502707 , B01L3/502715 , B01L2200/027 , B01L2200/0631 , B01L2300/0681 , B01L2300/0816 , B01L2300/0887 , B01L2300/12 , G01N27/44791 , G01N30/6095 , Y10T29/49826 , Y10T156/10
摘要： Techniques and devices are provided related to insert assemblies that may be used in conjunction with microfluidic devices. In one embodiment, the insert assemblies include a functional material, such as a solid stationary phase, that may be coupled to a microfluidic pathway via the insert assembly. In this manner, solid stationary phase materials that may be challenging to directly apply to a microfluidic device may be separately enclosed inside the insert element prior to assembly into a microfluidic device, such as a microfluidic chip.
摘要翻译： 提供了与可与微流体装置结合使用的插入组件相关的技术和装置。 在一个实施例中，插入组件包括可经由插入组件耦合到微流体通路的功能材料，例如固体固定相。 以这种方式，在组装成微流体装置（例如微流体芯片）之前，可能难以直接应用于微流体装置的固体固相材料可以单独包封在插入元件内部。
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公开(公告)号：US20180078937A1
公开(公告)日：2018-03-22
申请号：US15267479
申请日：2016-09-16
CPC分类号： B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L2200/025 , B01L2200/027 , B01L2200/0689 , B01L2200/12 , B01L2300/0829 , B01L2300/0887 , B01L2300/123 , B01L2300/14 , B01L2400/0478 , B01L2400/0622 , B01L2400/0638 , B01L2400/0655 , F16K99/0015 , F16K99/0055 , G01N35/10 , G01N2035/00247 , G01N2035/1044
摘要： Described herein is a system for on-demand synthesis/analysis of compounds and/or diagnostic applications. In general, any application that requires a low-cost binary switch valve array for fast (
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公开(公告)号：US10525466B2
公开(公告)日：2020-01-07
申请号：US15267479
申请日：2016-09-16
摘要： Described herein is a system for on-demand synthesis/analysis of compounds and/or diagnostic applications. In general, any application that requires a low-cost binary switch valve array for fast (
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公开(公告)号：US10363543B2
公开(公告)日：2019-07-30
申请号：US15132751
申请日：2016-04-19
发明人： Philipp Lang , Ruben Julian Salvamoser , Victor Donald Samper , Christian Friedrich Peter Rensch
摘要： Fluid transport approaches are described that operate without the need for precise displacement of an actuator and with little or no sensing in the flow path. In certain implementations, a gas phase in a fluid reservoir is compressed by a pressure source such that releasing the pressure, such as by opening a valve to an intermediary conduit, displaces fluid to the intermediary chamber. Closing that fluid path and opening a different fluid path to a chamber at ambient temperature causes the fluid to be displaced to the chamber.
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公开(公告)号：US20180052065A1
公开(公告)日：2018-02-22
申请号：US15240772
申请日：2016-08-18
CPC分类号： G01L1/127 , G01L1/12 , G01L3/101 , G01L3/102 , H01F27/2804 , H01F38/20 , H01L41/125 , H05K1/18 , H05K2201/1003
摘要： A sensor for sensing stress in a ferromagnetic material includes a non-magnetic substrate. The substrate has a first surface and a second surface opposite the first surface. A first coil is attached to or formed on the first surface of the substrate. The first coil is configured to induce a magnetic flux in the ferromagnetic material being driven by an alternating current (AC) signal. At least one second coil is attached to or formed on the first surface of the substrate. The at least one second coil is spaced from the first coil. In addition, the second coil is configured to detect changes in the magnetic flux induced in the ferromagnetic material.
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