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25 条记录 (耗时 0.023 秒)

    Chip for performing an electrophoretic separation of molecules and method using same
    1.
    发明授权
    Chip for performing an electrophoretic separation of molecules and method using same 失效
    用于进行分子的电泳分离的芯片和使用其的方法

    公开(公告)号：US06254754B1

    公开(公告)日：2001-07-03

    申请号：US09361063

    申请日：1999-07-26

    申请人： Gordon Ross ,  Patrick Kaltenbach

    发明人： Gordon Ross ,  Patrick Kaltenbach

    IPC分类号： G01N2726

    CPC分类号： G01N27/44791 ,  G01N27/44704 ,  G01N27/44773

    摘要： A chip for performing an electrophoretic separation of micromolecular or macromolecular structures in two dimensions comprises a base substrate comprising a main surface. A channel is formed in the main surface of said base substrate in a first direction, wherein a first voltage is applicable across the channel in order to allow a separation of micromolecular structures or macromolecular structures in the first direction on the basis of a first separation mechanism. In addition, a two-dimensional separation matrix is formed in the main surface of the base substrate, wherein the separation matrix comprises a shallow recess and an array of stand-alone posts arranged in the recess. The recess extends perpendicular from the channel in a second direction, wherein a second voltage is applicable across the separation matrix in order to allow a separation of the structures on the basis of a second separation mechanism.

    摘要翻译： 用于在二维中进行小分子或大分子结构的电泳分离的芯片包括包括主表面的基底。 在所述基底基板的主表面上沿第一方向形成通道，其中第一电压跨过通道应用，以便允许基于第一分离机构在第一方向上分离微分子结构或大分子结构 。 此外，在基底基板的主表面上形成二维分离基体，其中分离基体包括浅凹槽和布置在凹槽中的独立柱阵列。 所述凹部沿着第二方向从所述通道垂直延伸，其中第二电压跨越所述分离矩阵适用，以允许基于第二分离机构分离所述结构。

    Apparatus for the operation of a microfluidic device
    2.
    发明授权
    Apparatus for the operation of a microfluidic device 有权
    用于操作微流体装置的装置

    公开(公告)号：US06811668B1

    公开(公告)日：2004-11-02

    申请号：US09595420

    申请日：2000-06-15

    申请人： Manfred Berndt ,  Patrick Kaltenbach ,  Colin B. Kennedy

    发明人： Manfred Berndt ,  Patrick Kaltenbach ,  Colin B. Kennedy

    IPC分类号： C02F140

    CPC分类号： B01L3/502715 ,  B01L2200/027 ,  B01L2200/10 ,  B01L2300/0819 ,  B01L2400/0421

    摘要： In a system for operation or handling of a laboratory microchip (41) for chemical processing or analysis, the microchip (41) is mounted in a first physical unit (42). The microchip (41) is arranged on a mounting plate, such that it is readily accessible from the top and thus the fitting and removal of the microchip is considerably simplified. Furthermore, the first physical unit (42) comprises an optical device (43) for contactless detection of the results of the chemical processes conducted on the microchip. The supply systems necessary for the operation of the microchip are arranged in a module unit that has a separable connection with a second physical unit. The proposed modular layout enables ease of interchangeability of the required supply systems and thus, overall, ease of adaptability of the proposed system for various types of microchips.

    摘要翻译： 在用于操作或处理用于化学处理或分析的实验室微芯片（41）的系统中，微芯片（41）安装在第一物理单元（42）中。 微芯片（41）布置在安装板上，使得其从顶部容易接近，因此微芯片的装配和移除被大大简化。 此外，第一物理单元（42）包括用于非接触式检测在微芯片上进行的化学处理结果的光学装置（43）。 微芯片操作所需的供电系统被布置在与第二物理单元具有可分离连接的模块单元中。 所提出的模块化布局使得所需供应系统的可互换性变得容易，并且因此总体而言，所提出的系统适用于各种类型的微芯片。

    Low voltage miniaturized column analytical apparatus and method
    7.
    发明授权
    Low voltage miniaturized column analytical apparatus and method 失效
    低压小型化柱分析仪和方法

    公开(公告)号：US5645702A

    公开(公告)日：1997-07-08

    申请号：US483217

    申请日：1995-06-07

    申请人： Klaus E. Witt ,  Patrick Kaltenbach ,  Fritz Bek ,  Sally A. Swedberg ,  Laurie S. Mittelstadt

    发明人： Klaus E. Witt ,  Patrick Kaltenbach ,  Fritz Bek ,  Sally A. Swedberg ,  Laurie S. Mittelstadt

    IPC分类号： G01N27/447 ,  G01N30/02 ,  G01N30/60 ,  G01N27/26

    CPC分类号： G01N27/44773 ,  G01N30/02 ,  G01N30/60

    摘要： A miniaturized column analytical apparatus having a miniaturized column device containing a body with an elongate separation compartment is provided. Two or more sets of spaced apart antennas are positioned along the elongate separation compartment. The elongate separation compartment has first and second opposing sides along its elongate dimension. Each set of antenna contains a plurality of antennas. One antenna from each set is associated with at least one antenna from each of the other sets to form repeating sequences of antennas along the separation compartment on the opposing sides of the separation compartment. Each set of the antennas is associated with a different oscillating electrical potential to provide a plurality of oscillating electric fields along the elongate separation compartment to draw a target substance along the elongate separation compartment toward an exit end of the separation compartment. The detector can detect a target substance passing out of the elongate separation compartment.

    摘要翻译： 提供了一种小型化的柱分析装置，其具有包含具有细长隔离室的主体的小型化柱装置。 两个或更多组间隔开的天线沿着细长分隔室定位。 细长分离隔室具有沿其细长尺寸的第一和第二相对侧。 每组天线包含多个天线。 每组中的一个天线与至少一个其他组中的一个天线相关联，以在分隔室的相对侧上沿分隔室形成重复的天线序列。 每组天线与不同的振荡电势相关联，以沿着细长分隔室提供多个振荡电场，以沿着细长隔离室将目标物质拉向分离室的出口端。 检测器可以检测出从细长隔离室流出的目标物质。

    Contactless detection cell with reduced detection channel cross-section
    8.
    发明申请
    Contactless detection cell with reduced detection channel cross-section 审中-公开
    非接触检测单元具有减少的检测通道横截面

    公开(公告)号：US20090201035A1

    公开(公告)日：2009-08-13

    申请号：US10591646

    申请日：2004-06-07

    申请人： Patrick Kaltenbach ,  Klaus Witt ,  Bohuslav Gas ,  Tom Van De Goor

    发明人： Patrick Kaltenbach ,  Klaus Witt ,  Bohuslav Gas ,  Tom Van De Goor

    IPC分类号： G01R27/08 ,  G01N30/64

    CPC分类号： G01N27/4473 ,  G01N27/08 ,  G01N30/6095 ,  G01N30/64

    摘要： A contactless detection cell (1) for detecting an electrical property of one or more sample compounds in a flow path is described. The contactless detection cell (1) comprises a transmitter electrode (3) adapted for capacitively coupling an AC current into a detection channel (4) of the flow path, and a receiver electrode (5) adapted for receiving the AC current that has been coupled into the detection channel (4). An inner cross-section (IDDET) in at least a section of the detection channel is different than an inner cross-section (IDSEP) of the flow path (2) towards the detection channel (4).

    摘要翻译： 描述了用于检测流路中的一种或多种样品化合物的电特性的非接触检测电池（1）。 非接触式检测单元（1）包括适于将AC电流电容耦合到流路的检测通道（4）中的发射器电极（3）和适于接收已耦合的AC电流的接收器电极（5） 进入检测通道（4）。 检测通道的至少一部分中的内横截面（IDDET）不同于朝向检测通道（4）的流动路径（2）的内横截面（IDSEP）。

    Apparatus for the operation of a microfluidic device
    9.
    发明授权
    Apparatus for the operation of a microfluidic device 有权
    用于操作微流体装置的装置

    公开(公告)号：US07449096B2

    公开(公告)日：2008-11-11

    申请号：US10915744

    申请日：2004-08-11

    申请人： Manfred Berndt ,  Patrick Kaltenbach ,  Colin B. Kennedy

    发明人： Manfred Berndt ,  Patrick Kaltenbach ,  Colin B. Kennedy

    IPC分类号： G01N27/453 ,  B01L3/00

    CPC分类号： B01L3/502715 ,  B01L2200/027 ,  B01L2200/10 ,  B01L2300/0819 ,  B01L2400/0421

    摘要： In a system for operation or handling of a laboratory microchip (41) for chemical processing or analysis, the microchip (41) is mounted in a first physical unit (42). The microchip (41) is arranged on a mounting plate, such that it is readily accessible from the top and thus the fitting and removal of the microchip is considerably simplified. Furthermore, the first physical unit (42) comprises an optical device (43) for contactless detection of the results of the chemical processes conducted on the microchip. The supply systems necessary for the operation of the microchip are arranged in a module unit that has a separable connection with a second physical unit. The proposed modular layout enables ease of interchangeability of the required supply systems and thus, overall, ease of adaptability of the proposed system for various types of microchips.

    摘要翻译： 在用于操作或处理用于化学处理或分析的实验室微芯片（41）的系统中，微芯片（41）安装在第一物理单元（42）中。 微芯片（41）布置在安装板上，使得其从顶部容易接近，因此微芯片的装配和移除被大大简化。 此外，第一物理单元（42）包括用于非接触式检测在微芯片上进行的化学处理结果的光学装置（43）。 微芯片操作所需的供电系统被布置在与第二物理单元具有可分离连接的模块单元中。 所提出的模块化布局使得所需供应系统的可互换性变得容易，并且因此总体而言，所提出的系统适用于各种类型的微芯片。