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    Chromatographic two-layer particles
    1.
    发明授权
    Chromatographic two-layer particles 有权
    色谱双层颗粒

    公开(公告)号：US07208093B2

    公开(公告)日：2007-04-24

    申请号：US10526088

    申请日：2003-08-18

    申请人： Hans Berg ,  Philippe Busson ,  Mats Carlsson

    发明人： Hans Berg ,  Philippe Busson ,  Mats Carlsson

    IPC分类号： B01D15/08

    CPC分类号： B01D15/363 ,  B01D15/1807 ,  B01J20/285 ,  B01J20/286 ,  B01J20/3285 ,  B01J20/3293 ,  B01J39/26 ,  B01J41/20

    摘要： The present invention is a method of producing a chromatographic separation matrix, wherein porous polymeric particles comprised of two layers with different properties are prepared in a two-phase system by (a) providing porous polymeric particles with reactive groups on their surfaces; (b) washing said particles with a first solvent and draining the particles to enclose a first phase; (c) wetting the outer layer of the particles by adding a second solvent, which is essentially insoluble in the first solvent; (d) reacting the reactive groups in the outer layer by adding a reagent, which is essentially non-reactive in the first solvent; and (e) coupling of chromatographic binding groups to the reactive groups in the inner layer. The invention also encompasses a porous polymer particle suitable for use as a chromatographic separation matrix and a process of separation, wherein a matrix according to the invention is used.

    摘要翻译： 本发明是一种制备色谱分离基质的方法，其中通过（a）在其表面上提供具有反应性基团的多孔聚合物颗粒，在两相体系中制备由具有不同性质的两层组成的多孔聚合物颗粒。 （b）用第一溶剂洗涤所述颗粒并排出颗粒以包围第一相; （c）通过加入基本不溶于第一溶剂的第二溶剂润湿颗粒外层; （d）通过添加在第一溶剂中基本上不反应的试剂使外层中的反应性基团反应; 和（e）色谱结合基团与内层中的反应性基团的偶合。 本发明还包括适合用作色谱分离基质的多孔聚合物颗粒和分离方法，其中使用根据本发明的基质。

    Chromatographic two-layer particles
    2.
    发明申请
    Chromatographic two-layer particles 有权
    色谱双层颗粒

    公开(公告)号：US20050242037A1

    公开(公告)日：2005-11-03

    申请号：US10526088

    申请日：2003-08-18

    申请人： Hans Berg ,  Philippe Busson ,  Mats Carlsson

    发明人： Hans Berg ,  Philippe Busson ,  Mats Carlsson

    IPC分类号： B01J20/281 ,  B01D15/18 ,  B01J20/28 ,  B01J20/285 ,  B01J20/286 ,  G01N30/00 ,  G01N30/88 ,  B01D15/08

    CPC分类号： B01D15/363 ,  B01D15/1807 ,  B01J20/285 ,  B01J20/286 ,  B01J20/3285 ,  B01J20/3293 ,  B01J39/26 ,  B01J41/20

    摘要： The present invention is a method of producing a chromatographic separation matrix, wherein porous polymeric particles comprised of two layers with different properties are prepared in a two-phase system by (a) providing porous polymeric particles with reactive groups on their surfaces; (b) washing said particles with a first solvent and draining the particles to enclose a first phase; (c) wetting the outer layer of the particles by adding a second solvent, which is essentially insoluble in the first solvent; (d) reacting the reactive groups in the outer layer by adding a reagent, which is essentially non-reactive in the first solvent; and (e) coupling of chromatographic binding groups to the reactive groups in the inner layer. The invention also encompasses a porous polymer particle suitable for use as a chromatographic separation matrix and a process of separation, wherein a matrix according to the invention is used.

    摘要翻译： 本发明是一种制备色谱分离基质的方法，其中通过（a）在其表面上提供具有反应性基团的多孔聚合物颗粒，在两相体系中制备由具有不同性质的两层组成的多孔聚合物颗粒。 （b）用第一溶剂洗涤所述颗粒并排出颗粒以包围第一相; （c）通过加入基本不溶于第一溶剂的第二溶剂润湿颗粒外层; （d）通过添加在第一溶剂中基本上不反应的试剂使外层中的反应性基团反应; 和（e）色谱结合基团与内层中的反应性基团的偶合。 本发明还包括适合用作色谱分离基质的多孔聚合物颗粒和分离方法，其中使用根据本发明的基质。

    Fairlead for guiding an anchoring chain and intended to be provided to anchoring equipment on the floor of a floating platform
    5.
    发明授权
    Fairlead for guiding an anchoring chain and intended to be provided to anchoring equipment on the floor of a floating platform 有权
    导轨用于引导锚链，并且旨在提供给浮动平台地板上的锚固设备

    公开(公告)号：US09567039B2

    公开(公告)日：2017-02-14

    申请号：US14362653

    申请日：2012-12-13

    申请人： Philippe Busson

    发明人： Philippe Busson

    IPC分类号： B63B21/10 ,  B63B21/18 ,  B63B21/50

    CPC分类号： B63B21/10 ,  B63B21/18 ,  B63B21/50

    摘要： A fairlead for guiding an anchor chain, intended to equip a ground anchor system for a floating platform, includes a bending structure for guiding a direction change of the associated anchor chain, and a locking structure that includes a grip jaw consisting of two jaws associated with operating elements for rotatably moving the jaws in opposite directions. The operating elements include: (a) an inert mass, referred to as “counterweight”, which is movably coupled to the jaws and which is height-adjustable between a low position and a high position corresponding to an active position and an inactive position of the jaws, respectively, so as to operate and tend to maintain the jaws in the active position, and (b) an actuator driven by control elements, for operating the jaws from the active position to the inactive position and for operating the counterweight from the low position to the high position.

    摘要翻译： 用于引导锚链的导轨，用于装备用于浮动平台的地面锚固系统，包括用于引导相关锚链的方向改变的弯曲结构，以及锁定结构，该锁定结构包括由两个相关联的两个钳口 用于沿相反方向可旋转地移动钳口的操作元件。 操作元件包括：（a）被称为“配重”的惰性物质，其可移动地联接到钳口，并且在对应于活动位置的低位置和高位置之间是高度可调节的， 颚爪分别操作并且倾向于将夹爪保持在主动位置，以及（b）由控制元件驱动的致动器，用于将夹爪从主动位置操作到非活动位置，并且用于将配重从 低位到高位。

    FAIRLEAD FOR GUIDING AN ANCHORING CHAIN AND INTENDED TO BE PROVIDED TO ANCHORING EQUIPMENT ON THE FLOOR OF A FLOATING PLATFORM
    6.
    发明申请
    FAIRLEAD FOR GUIDING AN ANCHORING CHAIN AND INTENDED TO BE PROVIDED TO ANCHORING EQUIPMENT ON THE FLOOR OF A FLOATING PLATFORM 有权
    用于指导锚链的意图和意图提供给浮动平台地板上的设备的锚固装置

    公开(公告)号：US20140339485A1

    公开(公告)日：2014-11-20

    申请号：US14362653

    申请日：2012-12-13

    申请人： Philippe Busson

    发明人： Philippe Busson

    IPC分类号： B63B21/10 ,  B63B21/50

    CPC分类号： B63B21/10 ,  B63B21/18 ,  B63B21/50

    摘要： A fairlead for guiding an anchor chain, intended to equip a ground anchor system for a floating platform, includes a bending structure for guiding a direction change of the associated anchor chain, and a locking structure that includes a grip jaw consisting of two jaws associated with operating elements for rotatably moving the jaws in opposite directions. The operating elements include: (a) an inert mass, referred to as “counterweight”, which is movably coupled to the jaws and which is height-adjustable between a low position and a high position corresponding to an active position and an inactive position of the jaws, respectively, so as to operate and tend to maintain the jaws in the active position, and (b) an actuator driven by control elements, for operating the jaws from the active position to the inactive position and for operating the counterweight from the low position to the high position.

    摘要翻译： 用于引导锚链的导轨，用于装备用于浮动平台的地面锚固系统，包括用于引导相关锚链的方向改变的弯曲结构，以及锁定结构，该锁定结构包括由两个相关联的两个钳口 用于沿相反方向可旋转地移动钳口的操作元件。 操作元件包括：（a）被称为“配重”的惰性物质，其可移动地联接到钳口，并且在对应于活动位置的低位置和高位置之间是高度可调节的， 颚爪分别操作并且倾向于将夹爪保持在主动位置，以及（b）由控制元件驱动的致动器，用于将夹爪从主动位置操作到非活动位置，并且用于将配重从 低位到高位。

    Polymeric support having novel pore structures
    7.
    发明授权
    Polymeric support having novel pore structures 失效
    具有新颖孔结构的聚合物载体

    公开(公告)号：US07662866B2

    公开(公告)日：2010-02-16

    申请号：US10517226

    申请日：2003-06-17

    申请人： Philippe Busson ,  Ronnie Palmgren ,  Michael Morrison

    发明人： Philippe Busson ,  Ronnie Palmgren ,  Michael Morrison

    IPC分类号： C08J9/26

    CPC分类号： B01J20/28092 ,  B01J20/26 ,  B01J20/267 ,  B01J20/28004 ,  B01J20/28019 ,  B01J20/28042 ,  B01J20/28057 ,  B01J20/28061 ,  B01J20/28097 ,  B01J20/285 ,  B01J20/3064 ,  B01J2220/82 ,  C08F2/18 ,  C08J9/26

    摘要： The invention is a method of producing a cross-linked polymeric support having a multimodal pore structure, which comprises providing a degradable initiator molecule; providing an organic phase comprising said initiator molecule, radically polymerizable monomers and a porogen in a solvent; providing an aqueous phase comprising a transition metal catalyst; suspension polymerization of the organic phase by adding a ligand, co-ordinating to the transition metal in the aqueous phase to produce a cross-linked polymeric support having a primary pore structure and comprising initiator molecule; and subjecting the support obtained to degrading conditions to remove the initiator molecule from within the support to produce a cross-linked polymeric support having a secondary pore structure in addition to the primary pore structure.

    摘要翻译： 本发明是一种生产具有多峰孔结构的交联聚合物载体的方法，其包括提供可降解的引发剂分子; 提供包含所述引发剂分子，可自由基聚合的单体和在溶剂中的致孔剂的有机相; 提供包含过渡金属催化剂的水相; 通过添加配体来悬浮聚合有机相，与水相中的过渡金属配位以产生具有一次孔结构并包含引发剂分子的交联聚合物载体; 并使获得的载体降解条件从支持体内除去引发剂分子，以产生除主孔结构之外具有二次孔结构的交联聚合物载体。

    Method for synthesis of acrylamide derivatives
    10.
    发明申请
    Method for synthesis of acrylamide derivatives 有权
    合成丙烯酰胺衍生物的方法

    公开(公告)号：US20070106090A1

    公开(公告)日：2007-05-10

    申请号：US10572294

    申请日：2004-10-18

    申请人： Mattias Algotsson ,  Philippe Busson ,  Nicolas Thevenin

    发明人： Mattias Algotsson ,  Philippe Busson ,  Nicolas Thevenin

    IPC分类号： C07C309/00

    CPC分类号： C07C277/08 ,  C07C279/12

    摘要： The present invention relates to a method for synthesis of an acrylamide derivative, starting with dissolving a salt of a nucleophilic amine in water to form an aqueous solution and desalting said solution with a base, comprising the following steps: a) addition of dissolved activated acrylic acid derivative to said solution; b) acidification of aqueous phase; and c) extraction of said aqueous phase. In a preferred embodiment the acryl amide derivative is an immobiline, preferably acrylamido agmatine. The preferred use of the immobilines is for production of 2D gels.

    摘要翻译： 本发明涉及一种合成丙烯酰胺衍生物的方法，首先将亲核胺的盐溶解在水中形成水溶液，并用碱脱盐所述溶液，包括以下步骤：a）加入溶解的活化丙烯酸 酸衍生物至所述溶液; b）水相酸化; 和c）提取所述水相。 在优选的实施方案中，丙烯酰胺衍生物是固定化物，优选丙烯酰胺基丁胺。 固定装置的优选用途是生产2D凝胶。