Linear motion apparatus
    1.
    发明授权
    Linear motion apparatus 失效
    直线运动装置

    公开(公告)号:US5806369A

    公开(公告)日:1998-09-15

    申请号:US730690

    申请日:1996-10-11

    摘要: A linear motion apparatus is comprised of: a toothed rail (40); a linearly driving mechanism section (50) having a plurality of swinging plates (53), crankshafts (54, 55), and a casing (51); and guiding means for guiding the casing (51) relatively movably with respect to the toothed rail (40). The casing (51) includes: a pair of side portions (61, 62) which are guided by the guiding means on both sides, in a tooth width direction, of the rail (40); a pair of end plate portions (63, 64) which are located on opposite sides, as viewed in a longitudinal direction of the rail (40), of the swinging plates (53) and connect opposite end portions of the pair of side plate portions (61, 62); and a coupling member (521) which is located between the plurality of crankshafts (54, 55) as viewed in the longitudinal direction of the rail and couple intermediate portions of the pair of side plate portions (61, 62). The coupling member (521) is preferably passed through the swinging plates (53). The linear motion apparatus is compact and low-cost, and capable of maintaining a stable state of meshing between swinging plates and a toothed rail even if a compact casing is adopted.

    摘要翻译: 线性运动装置包括:齿条(40); 具有多个摆动板(53),曲轴(54,55)和壳体(51)的直线驱动机构部(50)。 以及用于相对于所述齿条(40)相对可移动地引导所述壳体(51)的引导装置。 所述壳体(51)包括:一对侧部(61,62),其在所述导轨(40)的齿宽方向的两侧被所述引导装置引导; 一对端板部分(63,64),其位于相对侧的轨道(40)的纵向方向上的摆动板(53)中,并且连接该对侧板部分的相对端部 (61,62); 以及耦合构件(521),其位于所述多个曲轴(54,55)之间,并且在所述一对侧板部(61,62)的中心部分相连接。 联接构件(521)优选地通过摆动板(53)。 直线运动装置紧凑且成本低,并且即使采用紧凑的壳体,也能够保持摆动板和齿条之间的啮合的稳定状态。

    Intervertebral Disc Nucleus Pulposus Stem Cell/Progenitor Cell, The Cultivation Method And Intended Use Thereof
    7.
    发明申请
    Intervertebral Disc Nucleus Pulposus Stem Cell/Progenitor Cell, The Cultivation Method And Intended Use Thereof 审中-公开
    椎间盘髓核干细胞/祖细胞,培养方法及其用途

    公开(公告)号:US20130078222A1

    公开(公告)日:2013-03-28

    申请号:US13637470

    申请日:2011-03-29

    IPC分类号: C12N5/071

    摘要: Provided are intervertebral disk nucleus pulposus stem cells or progenitor cells that may be used for treatment of intervertebral disk disorders. An intervertebral disk nucleus pulposus cell is characterized by being isolated from the intervertebral disk nucleus pulposus of a vertebrate and is positive for at least one surface marker from among Tie2 and GD2. That is, the intervertebral disk nucleus pulposus stem cell is characterized by being at least Tie2-positive for the surface marker and) possesses a self-renewal ability as well as multipotency capable of differentiating into adipocytes, osteocytes, chondrocytes and neurons. Also provided is an intervertebral disk nucleus pulposus progenitor cell characterized by being at least Tie2-negative and GD2-positive for the surface marker and capable of differentiating into any of adipocytes, osteocytes, chondrocytes and neurons.

    摘要翻译: 提供可用于治疗椎间盘疾病的椎间盘髓核干细胞或祖细胞。 椎间盘髓核细胞的特征在于从脊椎动物的椎间盘髓核中分离,并且对于Tie2和GD2中的至少一个表面标记是阳性的。 也就是说,椎间盘髓核干细胞的特征在于对于表面标志物至少为Tie2阳性,并且具有能够分化成脂肪细胞,骨细胞,软骨细胞和神经元的自我更新能力以及多能性。 还提供了一种椎间盘髓核祖细胞,其特征在于对于表面标记至少具有Tie2阴性和GD2阳性,并且能够分化成任何脂肪细胞,骨细胞,软骨细胞和神经元。

    Hydrophilic film and process for producing the same
    8.
    发明授权
    Hydrophilic film and process for producing the same 失效
    亲水膜及其制造方法

    公开(公告)号:US06214382B1

    公开(公告)日:2001-04-10

    申请号:US08836049

    申请日:1997-12-23

    IPC分类号: A61K914

    CPC分类号: B01D67/0088

    摘要: This invention provides a hydrophilic membrane wherein a hydrophilic cellulose derivative of a number average molecular weight of 2000˜8000 is adsorbed irreversibly to a hydrophobic membrane of an aromatic polymer. Since an amount of leaching substances is extremely small, the membrane can be used suitably in such fields as medical applications, electronics, etc. where even a quite small quantity of leaching substances from the membranes is limited especially small.

    摘要翻译: 本发明提供一种亲水性膜,其中数均分子量为2000〜8000的亲水性纤维素衍生物不可逆地吸附在芳香族聚合物的疏水性膜上。由于浸出物质的量极少,因此可以适当地使用 诸如医疗应用,电子等领域,甚至来自膜的相当少量的浸出物质被限制得特别小。

    Mutual exclusion control apparatus for mutual exclusion control based on
locking and unlocking requests
    9.
    发明授权
    Mutual exclusion control apparatus for mutual exclusion control based on locking and unlocking requests 失效
    基于锁定和解锁请求的互斥控制互斥控制装置

    公开(公告)号:US5623671A

    公开(公告)日:1997-04-22

    申请号:US403107

    申请日:1995-03-13

    摘要: A mutual exclusion control is performed with dynamically, allocated lock variables. A lock request circuit issues a lock acquisition request or an unlock request. A lock identifying information holding circuit holds an identifying information related to a currently valid lock. A lock identifying information comparing circuit judges whether or not a lock identifying information from the lock request circuit is included in the lock identifying information holding circuit. A lock identifying information updating circuit updates the lock identifying information holding circuit on the basis of the request from the lock request circuit.

    摘要翻译: 使用动态分配的锁定变量执行互斥控制。 锁定请求电路发出锁定获取请求或解锁请求。 锁识别信息保持电路保存与当前有效锁相关的识别信息。 锁定识别信息比较电路判断锁定识别信息保持电路中是否包含来自锁定请求电路的锁定识别信息。 锁识别信息更新电路根据来自锁定请求电路的请求更新锁定识别信息保持电路。

    Method of constructing spinal injury model monkey and utilization thereof
    10.
    发明授权
    Method of constructing spinal injury model monkey and utilization thereof 有权
    构建脊髓损伤模型猴的方法及其应用

    公开(公告)号:US07753054B2

    公开(公告)日:2010-07-13

    申请号:US10496993

    申请日:2002-11-26

    IPC分类号: A61B19/00

    摘要: A method for creating a monkey model of spinal cord injury, which includes exposing the dura mater of the cervical cord of a monkey and applying a load on the dura mater; the thus-created monkey model of spinal cord injury; and a method for evaluating a therapeutic drug for spinal cord injury by use of this model.According to the present invention, it is possible to create a monkey which is close to the human and thus useful as a model of human spinal cord injury. This model enables proper evaluation of therapeutic effects of various drugs on spinal cord injury. Through use of this model, it has been confirmed for the first time that transplantation therapy of human neural stem cells is efficacious against spinal cord injury.

    摘要翻译: 一种创建脊髓损伤猴模型的方法,其包括暴露猴子的颈椎硬脑膜并在硬脑膜上施加负荷; 由此造成的脊髓损伤猴模型; 以及使用该模型评价脊髓损伤治疗药物的方法。 根据本发明,可以产生靠近人类的猴,因此可用作人脊髓损伤的模型。 该模型能够适当评估各种药物对脊髓损伤的治疗效果。 通过使用该模型,人类神经干细胞的移植治疗首次对脊髓损伤有效。