Detection system and method for high sensitivity fluorescent assays
    1.
    发明授权
    Detection system and method for high sensitivity fluorescent assays 有权
    用于高灵敏度荧光测定的检测系统和方法

    公开(公告)号:US08309369B2

    公开(公告)日:2012-11-13

    申请号:US13224174

    申请日:2011-09-01

    IPC分类号: G01N33/543

    摘要: This invention relates to a detection system for measuring a fluorescent signal in a fluorescent assay. The system comprises a probe having a small sensing surface bound with a fluorescent label, and a light source and a detector both mounted at the proximal side of the sensing surface of the substrate. The invention also relates to a method for detecting an analyte in a liquid sample using a probe tip having a small surface area (≦5 mm) and a high molecular weight polymer (≧1 MD) having multiple binding molecules and multiple fluorescent labels. The binding reaction is accelerated by flowing the reaction solutions laterally and moving the probe tip up and down in the reaction vessels. The invention furthers relates to a fluorescent labeling composition comprising a cross-linked Ficoll molecule having a plurality of binding molecules and a plurality of fluorescent labels.

    摘要翻译: 本发明涉及一种用于在荧光测定中测量荧光信号的检测系统。 该系统包括具有与荧光标签结合的小感测表面的探针,以及安装在基底的感测表面的近侧的光源和检测器。 本发明还涉及一种使用具有小表面积(&NlE; 5mm)的探针尖端和具有多个结合分子和多个荧光标记的高分子量聚合物(≥1MD)来检测液体样品中的分析物的方法。 通过横向流动反应溶液并在反应容器中上下移动探针尖端来加速结合反应。 本发明还涉及包含具有多个结合分子和多个荧光标记的交联Ficoll分子的荧光标记组合物。

    DETECTION SYSTEM AND METHOD FOR HIGH SENSITIVITY FLUORESCENT ASSAYS
    2.
    发明申请
    DETECTION SYSTEM AND METHOD FOR HIGH SENSITIVITY FLUORESCENT ASSAYS 有权
    检测系统和高灵敏度荧光测定方法

    公开(公告)号:US20110312105A1

    公开(公告)日:2011-12-22

    申请号:US13224174

    申请日:2011-09-01

    IPC分类号: G01N21/64 C07K14/36 C07K16/00

    摘要: This invention relates to a detection system for measuring a fluorescent signal in a fluorescent assay. The system comprises a probe having a small sensing surface bound with a fluorescent label, and a light source and a detector both mounted at the proximal side of the sensing surface of the substrate. The invention also relates to a method for detecting an analyte in a liquid sample using a probe tip having a small surface area (≦5 mm) and a high molecular weight polymer (≧1 MD) having multiple binding molecules and multiple fluorescent labels. The binding reaction is accelerated by flowing the reaction solutions laterally and moving the probe tip up and down in the reaction vessels. The invention furthers relates to a fluorescent labeling composition comprising a cross-linked Ficoll molecule having a plurality of binding molecules and a plurality of fluorescent labels.

    摘要翻译: 本发明涉及一种用于在荧光测定中测量荧光信号的检测系统。 该系统包括具有与荧光标签结合的小感测表面的探针,以及安装在基底的感测表面的近侧的光源和检测器。 本发明还涉及一种使用具有小表面积(&NlE; 5mm)的探针尖端和具有多个结合分子和多个荧光标记的高分子量聚合物(≥1MD)来检测液体样品中的分析物的方法。 通过横向流动反应溶液并在反应容器中上下移动探针尖端来加速结合反应。 本发明还涉及包含具有多个结合分子和多个荧光标记的交联Ficoll分子的荧光标记组合物。

    Bottle cap
    3.
    外观设计

    公开(公告)号:USD1019259S1

    公开(公告)日:2024-03-26

    申请号:US29911297

    申请日:2023-08-31

    申请人: Jun Chen

    设计人: Jun Chen

    摘要: FIG. 1 is a top perspective view of a bottle cap, showing my new design;
    FIG. 2 is a bottom perspective view thereof;
    FIG. 3 is a front view thereof;
    FIG. 4 is a rear view thereof;
    FIG. 5 is a left side view thereof;
    FIG. 6 is a right side view thereof;
    FIG. 7 is a top view thereof; and,
    FIG. 8 is a bottom view thereof.
    The dashed broken lines depict portions of the bottle cap that form no part of the claim design.

    Making a memoristic array with an implanted hard mask

    公开(公告)号:US11569440B2

    公开(公告)日:2023-01-31

    申请号:US15412076

    申请日:2017-01-23

    摘要: The invention disclosed a method to make an implanted hard mask with ultra-small dimensions for fabricating integrated nonvolatile random access memory. Instead of directly depositing hard mask material on top of the memory film stack element, we first make ultra-small VIA holes on a pattern transfer molding (PTM) layer using a reverse memory mask, then fill in the hard mask material into the VIA holes within the PTM material. Ultra-small hard mask pillars are formed after removing the PTM material. To improve the adhesion of the hard mask pillars with the underneath memory stack element, a hard mask sustaining element (HMSE) is added below PTM. Due to a better materials adhesion between HMSE and the hard mask, a stronger hard mask array can be formed.

    COMPOSITE MULTI-STACK SEED LAYER TO IMPROVE PMA FOR PERPENDICULAR MAGNETIC PINNING

    公开(公告)号:US20210343934A1

    公开(公告)日:2021-11-04

    申请号:US16865810

    申请日:2020-05-04

    摘要: The invention comprises a novel composite multi-stack seed layer (CMSL) having lattice constant matched crystalline structure with the Co layer in above perpendicular magnetic pinning layer (pMPL) so that an excellent epitaxial growth of magnetic super lattice pinning layer [Co/(Pt, Pd or Ni)]n along its FCC (111) orientation can be achieved, resulting in a significant enhancement of perpendicular magnetic anisotropy (PMA) for perpendicular spin-transfer-torque magnetic-random-access memory (pSTT-MRAM) using perpendicular magnetoresistive elements as basic memory cells which potentially replace the conventional semiconductor memory used in electronic chips, especially mobile chips for power saving and non-volatility.

    BOTTOM-PINNED MAGNETIC RANDOM ACCESS MEMORY HAVING A COMPOSITE SOT STRUCTURE

    公开(公告)号:US20210327960A1

    公开(公告)日:2021-10-21

    申请号:US16849571

    申请日:2020-04-15

    摘要: An ultra-fast magnetic random access memory (MRAM) comprises a three terminal bottom-pinned composite SOT magnetic tunneling junction (bCSOT-MTJ) element including (counting from top to bottom) a magnetic flux guide (MFG) having a very high magnetic permeability, a spin Hall channel (SHC) having a large positive spin Hall angle, an in-plane magnetic memory (MM) layer, a tunnel barrier (TB) layer, and a magnetic pinning stack (MPS) having a synthetic antiparallel coupling pinned by an antiferromagnetic material. The magnetic writing is significantly boosted by a combined effort of enhanced spin orbit torque (SOT) and Lorentz force generated by current-flowing wire (CFW) in the SHC layer and spin transfer torque (STT) by a current flowing through the MTJ stack, and further enhanced by a magnetic close loop formed at the cross section of MFG/SHC/MM tri-layer. Such bCSOT-MTJ element will have a very fast (down to picoseconds) switching speed and consume much less power suitable level 1 or 2 cache application for SMRAM, CPU, GPU and TPU.

    Synthetic magnetic pinning element having strong antiferromagnetic coupling

    公开(公告)号:US11081154B1

    公开(公告)日:2021-08-03

    申请号:US16773283

    申请日:2020-01-27

    摘要: The present invention discloses an enhanced synthetic antiferromagnetic (eSAF) element with a very strong RKKY coupling comprising a magnetic pinning layer having a face-center-cubic (fcc) crystalline structure and a magnetic reference layer having a body-center-cubic (bcc) crystalline structure which are antiferromagnetically coupled by a composite non-magnetic spacer (CnmS) containing a bi-layer of (Ru, Rh or Ir)/Cr or tri-layer of (Ru, Rh, or Ir)/(W, Mo, or V)/Cr. With such eSAF, a strong magnetic pinning element is formed which can be used to make various thin STT-MRAM film stacks with good thermal and magnetic stability while maintaining high TMR value.

    Display for embedded intelligence
    9.
    发明授权
    Display for embedded intelligence 有权
    显示嵌入式智能

    公开(公告)号:US09262035B1

    公开(公告)日:2016-02-16

    申请号:US13443200

    申请日:2012-04-10

    IPC分类号: G06F3/048 G06F17/25

    摘要: A system for displaying an embedded intelligence applet comprises a processor and a memory. The processor is configured to provide display information to display in the embedded intelligence applet window and to provide an indication to display the embedded intelligence applet window in an opaque mode. The processor is configured to determine whether an indication to activate a window other than the embedded intelligence applet window is received. The processor is configured to provide an indication to display the embedded intelligence applet window in a partially transparent mode in the event that an indication to activate a window other than the embedded intelligence applet window is received. The memory is coupled to the processor and is configured to provide the processor with instructions.

    摘要翻译: 用于显示嵌入式智能小应用程序的系统包括处理器和存储器。 处理器被配置为提供显示信息以在嵌入式智能小应用程序窗口中显示并且提供以不透明模式显示嵌入式智能小应用程序窗口的指示。 处理器被配置为确定是否接收到激活除嵌入式智能小程序窗口之外的窗口的指示。 处理器被配置为在接收到激活不同于嵌入式智能小应用程序窗口的窗口的指示的情况下,提供在部分透明模式下显示嵌入式智能小应用程序窗口的指示。 存储器耦合到处理器并且被配置为向处理器提供指令。

    System for Harvesting Water Wave Energy
    10.
    发明申请
    System for Harvesting Water Wave Energy 有权
    水波能量收获系统

    公开(公告)号:US20160040648A1

    公开(公告)日:2016-02-11

    申请号:US14819142

    申请日:2015-08-05

    IPC分类号: F03B13/18 F03B13/10

    摘要: A generator for harvesting energy from water in motion includes a sheet of a hydrophobic material, having a first side and an opposite second side, that is triboelectrically more negative than water. A first electrode sheet is disposed on the second side of the sheet of a hydrophobic material. A second electrode sheet is disposed on the second side of the sheet of a hydrophobic material and is spaced apart from the first electrode sheet. Movement of the water across the first side induces an electrical potential imbalance between the first electrode sheet and the second electrode sheet.

    摘要翻译: 用于从运动中的水中收集能量的发生器包括具有第一侧和相对的第二侧的疏水材料片,其比水更摩擦地更负。 第一电极片设置在疏水材料片的第二面上。 第二电极片设置在疏水材料的片材的第二侧上并与第一电极片间隔开。 水的移动通过第一侧引起第一电极片和第二电极片之间的电势不平衡。