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    Apparatus and methods for preparing an emulsion
    6.
    发明授权
    Apparatus and methods for preparing an emulsion 有权

    公开(公告)号：US10258941B2

    公开(公告)日：2019-04-16

    申请号：US13334154

    申请日：2011-12-22

    申请人： Bruce W. Hudson ,  Gary W. Opperman ,  Adrian T. Raiche

    发明人： Bruce W. Hudson ,  Gary W. Opperman ,  Adrian T. Raiche

    IPC分类号： A01N25/04 ,  B01F3/08 ,  B01F5/06 ,  B01J19/00

    摘要： Disclosed herein are apparatus and methods for producing emulsions, and, in particular, for maintaining laminar flow during production of emulsions containing microsuspensions. Disclosed herein are columns for receiving a packing material that permits fluid flow through the column. The columns have a periphery that defines an interior cavity in fluid communication with inlets and outlets of the column. Disclosed herein is a method of preparing an emulsion that includes (1) forming a first phase typically containing an organic solvent, a polymer, and one or more biologically active agents and/or chemicals; (2) forming a second phase typically containing water as the second solvent, an emulsion stabilizer and optionally a solvent; and (3) passing the first and the second phases through the column to form a “water in oil” type emulsion.

    Implant devices that differ by release profile and methods of making and using same
    9.
    发明授权
    Implant devices that differ by release profile and methods of making and using same 有权
    种植体装置根据发行情况和制作和使用方法不同而不同

    公开(公告)号：US09399018B2

    公开(公告)日：2016-07-26

    申请号：US12883415

    申请日：2010-09-16

    申请人： Bruce W. Hudson ,  Peter Markland

    发明人： Bruce W. Hudson ,  Peter Markland

    IPC分类号： A61K9/14 ,  A61K9/50 ,  A61K9/00 ,  A61K38/09

    CPC分类号： A61K9/146 ,  A61K9/0024 ,  A61K9/5084 ,  A61K38/09

    摘要： Described herein are implant devices, kits comprising the implant devices, and methods of making and using the devices and kits. In one aspect, a plurality of implant devices comprises at least two implants that exhibit a different release profile of a bioactive agent. In another aspect, an implant device comprises one or more adjoined polymer bodies, wherein at least two of the polymer bodies provide a different release profile of a bioactive agent. In another aspect, a kit comprises one or more disclosed implant devices. In another aspect, methods of delivering a bioactive agent to a subject comprise administering to the subject one or more disclosed implant devices.

    摘要翻译： 本文描述的是植入装置，包括植入装置的套件以及制造和使用装置和试剂盒的方法。 在一个方面，多个植入装置包括表现出生物活性剂的不同释放曲线的至少两个植入物。 在另一方面，植入装置包括一个或多个邻接的聚合物体，其中至少两个聚合物体提供生物活性剂的不同释放曲线。 在另一方面，试剂盒包括一个或多个公开的植入装置。 在另一方面，将生物活性剂递送到受试者的方法包括向受试者施用一个或多个公开的植入装置。

    Implant Devices that Differ by Release Profile and Methods of Making and Using Same
    10.
    发明申请
    Implant Devices that Differ by Release Profile and Methods of Making and Using Same 有权
    种植体设备不同于释放轮廓和使用相同的方法

    公开(公告)号：US20110142906A1

    公开(公告)日：2011-06-16

    申请号：US12883415

    申请日：2010-09-16

    申请人： Bruce W. Hudson ,  Peter Markland

    发明人： Bruce W. Hudson ,  Peter Markland

    IPC分类号： A61K9/00 ,  A61K38/09

    CPC分类号： A61K9/146 ,  A61K9/0024 ,  A61K9/5084 ,  A61K38/09

    摘要： Described herein are implant devices, kits comprising the implant devices, and methods of making and using the devices and kits. In one aspect, a plurality implant devices comprises at least two implants that exhibit a different release profile of a bioactive agent. In another aspect, an implant device comprises one or more adjoined polymer bodies, wherein at least two of the polymer bodies provide a different release profile of a bioactive agent. In another aspect, a kit comprises one or more disclosed implant devices. In another aspect, methods of delivering a bioactive agent to a subject comprise administering to the subject one or more disclosed implant devices.

    摘要翻译： 本文描述的是植入装置，包括植入装置的套件以及制造和使用装置和试剂盒的方法。 在一个方面，多个植入装置包括表现出生物活性剂的不同释放曲线的至少两个植入物。 在另一方面，植入装置包括一个或多个邻接的聚合物体，其中至少两个聚合物体提供生物活性剂的不同释放曲线。 在另一方面，试剂盒包括一个或多个公开的植入装置。 在另一方面，将生物活性剂递送到受试者的方法包括向受试者施用一个或多个公开的植入装置。