-
公开(公告)号：US20060156744A1
公开(公告)日：2006-07-20
申请号：US11268383
申请日：2005-11-07
申请人： James Cusiter , David Carpenter , Rene Spaarman , Andrew Stephens , Steven Bowring , Eveline Otten , Harke Meek
发明人： James Cusiter , David Carpenter , Rene Spaarman , Andrew Stephens , Steven Bowring , Eveline Otten , Harke Meek
CPC分类号： B63B25/16 , B63B35/44 , B63B38/00 , F17C5/06 , F17C7/04 , F17C9/02 , F17C2201/052 , F17C2205/0107 , F17C2205/0126 , F17C2205/0157 , F17C2221/033 , F17C2221/035 , F17C2223/0153 , F17C2223/0161 , F17C2223/033 , F17C2225/0123 , F17C2225/035 , F17C2227/0393 , F17C2265/05 , F17C2270/0102 , F17C2270/0105 , F17C2270/0113 , F17C2270/0126
摘要： An offshore liquefied natural gas floating storage regasification unit that may receive, store, and process liquefied natural gas from carriers. A floating storage regasification unit may include transfer equipment to offload liquefied natural gas from a carrier, a first mooring system to provide for mooring of a floating storage regasification unit at a location in a body of water, a second mooring system to provide for mooring a carrier to the floating storage regasification unit, and combinations thereof. A portion of the floating storage regasification unit may be composed of a double-hull containment structure.
摘要翻译： 离岸液化天然气浮选储存再生单元，可以从运输船接收，储存和处理液化天然气。 浮动储存再气化单元可以包括从载体卸载液化天然气的转运设备，第一系泊系统，用于在水体中的位置提供浮动储存再气化单元的系泊;第二系泊系统，用于系泊系泊 载体到浮选存储再气化单元，以及它们的组合。 浮动储存再气化单元的一部分可以由双壳体容纳结构构成。
-
公开(公告)号：US20050172645A1
公开(公告)日：2005-08-11
申请号：US10498339
申请日：2002-12-12
申请人： Alan Bliault , James Cusiter , Andrew Stephens
发明人： Alan Bliault , James Cusiter , Andrew Stephens
CPC分类号： B63B15/00 , B63B35/44 , B63B43/00 , B63B2035/448 , F25J1/0022 , F25J1/0278 , F25J3/0209 , F25J3/0233 , F25J3/0238 , F25J3/0295 , F25J2290/40 , F25J2290/42 , F25J2290/72
摘要： A floating hydrocarbon treating plant containing a vessel having a hull and a deck and having tanks located below the deck for storing hydrocarbons, and a plant for treating hydrocarbons located at the deck of the vessel is provided. The plant for treating hydrocarbons includes spaced-apart modules, wherein each module has related plant equipment mounted on a module floor, and the modules rest on closed support girders that extend under the module in a direction perpendicular to the edge of the deck, and wherein the module floor is secured to one of the closed support girders.
摘要翻译： 一种含有船体和甲板并且具有位于甲板下面用于储存烃的罐的浮动烃处理装置，以及用于处理位于船舶甲板处的烃的设备。 用于处理碳氢化合物的设备包括间隔开的模块，其中每个模块具有安装在模块地板上的相关工厂设备，并且模块搁置在在垂直于甲板边缘的方向上在模块下方延伸的封闭的支撑梁上，并且其中 模块底板固定在一个封闭的支撑梁上。
-
公开(公告)号：US20070010473A1
公开(公告)日：2007-01-11
申请号：US11508024
申请日：2006-08-22
申请人： Judy Ruckman , Larry Gold , Andrew Stephens , Nebojsa Janjic
发明人： Judy Ruckman , Larry Gold , Andrew Stephens , Nebojsa Janjic
IPC分类号： A61K48/00
CPC分类号： C07H21/00 , A61K38/00 , C12N15/115 , C12N2310/16 , C12N2310/322 , G01N33/5308 , G01N33/74 , G01N2333/4753 , C12N2310/3533 , C12N2310/321 , C12N2310/3521
摘要： Methods are described for the isolation of nucleic acid ligands to integrins using the SELEX process. SELEX is an acronym for Systematic Evolution of Ligands by EXponential enrichment. The nucleic acid ligands of the present invention are useful as therapeutic and diagnostic agents.
摘要翻译： 描述了使用SELEX方法将核酸配体分离为整联蛋白的方法。 SELEX是指数浓缩的配体的系统演化的缩写。 本发明的核酸配体可用作治疗和诊断剂。
-
公开(公告)号：US6127119A
公开(公告)日：2000-10-03
申请号：US976413
申请日：1997-11-21
申请人： Andrew Stephens , Larry Gold , Ulrich Speck
发明人： Andrew Stephens , Larry Gold , Ulrich Speck
IPC分类号： C12N15/09 , A61K38/00 , C07B61/00 , C07H19/06 , C07H19/10 , C07H21/00 , C07H23/00 , C07K7/22 , C07K14/00 , C07K14/16 , C07K14/72 , C12N9/12 , C12N15/10 , C12N15/115 , C12Q1/37 , C12Q1/68 , C12Q1/70 , F02B75/02 , G01N33/53 , G01N33/531 , G01N33/532 , G01N33/535 , G01N33/569 , G01N33/68 , G01N33/76 , C07H21/02 , C07H21/04 , C12P19/34
CPC分类号： A61K47/48076 , A61K47/48092 , B82Y5/00 , C07H19/06 , C07H19/10 , C07H21/00 , C07K14/001 , C07K14/005 , C07K14/72 , C07K7/22 , C12N15/1048 , C12N15/115 , C12N9/1276 , C12Q1/37 , G01N33/53 , G01N33/531 , G01N33/532 , G01N33/535 , G01N33/56988 , G01N33/68 , G01N33/76 , A61K38/00 , C12N2310/13 , C12N2310/16 , C12N2310/321 , C12N2310/322 , C12N2310/344 , C12N2310/53 , C12N2740/16222 , C40B40/00 , F02B2075/027 , G01N2333/16 , G01N2333/163 , G01N2333/4724 , G01N2333/503 , G01N2333/575 , G01N2333/62 , G01N2333/7056 , G01N2333/8125 , G01N2333/96433 , G01N2333/96436 , G01N2333/96455 , G01N2333/96486 , G01N2333/966 , G01N2333/9726 , G01N2333/974 , G01N2333/976
摘要： This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to blood vessels are described.
摘要翻译： 本发明公开了复合组织靶的高亲和力寡核苷酸配体，特别是具有结合复合组织靶的能力的核酸配体，以及获得这种配体的方法。 组织靶包括细胞，亚细胞组分，聚集体或细胞，细胞集合和更有序结构。 具体地，描述了对血管的核酸配体。
-
公开(公告)号：US06737236B1
公开(公告)日：2004-05-18
申请号：US09341337
申请日：1999-07-08
申请人： Wolfgang Pieken , Ken Hill , Bruce Eaton , Danny McGee , Kurt Vagle , Larry Gold , Andrew Stephens
发明人： Wolfgang Pieken , Ken Hill , Bruce Eaton , Danny McGee , Kurt Vagle , Larry Gold , Andrew Stephens
IPC分类号： C12Q168
CPC分类号： C12N15/113 , B01J2219/00423 , B01J2219/00452 , B01J2219/00497 , B01J2219/00527 , B01J2219/00599 , B01J2219/00686 , B01J2219/00707 , B01J2219/00722 , B01J2219/00725 , C07B2200/11 , C07C271/22 , C07C2603/18 , C07H19/04 , C07H19/10 , C07H21/00 , C07K1/023 , C07K1/063 , C12N2310/351 , C40B40/06 , C40B40/10 , C40B50/08 , C40B60/14
摘要： This invention discloses a novel method for conjugating macromolecules to other molecular entities. Specifically, this invention discloses a method for conjugating or derivatizing macromolecules, such as oligonucleotides and proteins, using cycloaddition reactions, such as the Diels-Alder reaction or 1,3-dipolar cycloadditions. Included in the invention are the novel bioconjugated macromolecules that can be prepared according to the method of the invention.
摘要翻译： 本发明公开了一种将大分子与其他分子实体结合的新方法。 具体地说，本发明公开了一种使用环加成反应如Diels-Alder反应或1,3-偶极环加成来共轭或衍生大分子如寡核苷酸和蛋白质的方法。 本发明包括可根据本发明方法制备的新型生物共轭大分子。
-
公开(公告)号：US5750342A
公开(公告)日：1998-05-12
申请号：US433124
申请日：1995-05-03
申请人： Andrew Stephens , Dan Schneider , Larry Gold , Ulrich Speck
发明人： Andrew Stephens , Dan Schneider , Larry Gold , Ulrich Speck
IPC分类号： A61K38/00 , C07B61/00 , C07H19/06 , C07H19/10 , C07H21/00 , C07K7/22 , C07K14/00 , C07K14/16 , C07K14/72 , C12N9/12 , C12N15/10 , C12N15/115 , C12Q1/37 , C12Q1/68 , C12Q1/70 , F02B75/02 , G01N33/53 , G01N33/531 , G01N33/532 , G01N33/535 , G01N33/569 , G01N33/68 , G01N33/76 , C07H21/02 , C07H21/04
CPC分类号： A61K47/48092 , A61K47/48076 , B82Y5/00 , C07H19/06 , C07H19/10 , C07H21/00 , C07K14/001 , C07K14/005 , C07K14/72 , C07K7/22 , C12N15/1048 , C12N15/115 , C12N9/1276 , C12Q1/37 , C12Q1/6811 , G01N33/53 , G01N33/531 , G01N33/532 , G01N33/535 , G01N33/56988 , G01N33/68 , G01N33/6842 , G01N33/76 , A61K38/00 , C12N2310/13 , C12N2310/322 , C12N2310/53 , C12N2740/16222 , C40B40/00 , F02B2075/027 , G01N2333/16 , G01N2333/163 , G01N2333/4724 , G01N2333/503 , G01N2333/575 , G01N2333/62 , G01N2333/7056 , G01N2333/8125 , G01N2333/96433 , G01N2333/96436 , G01N2333/96455 , G01N2333/96486 , G01N2333/966 , G01N2333/9726 , G01N2333/974 , G01N2333/976
摘要： This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to peripheral blood mononuclear cells (PBMC), fibrin clots, and carotid arteries are described.
摘要翻译： 本发明公开了复合组织靶的高亲和力寡核苷酸配体，特别是具有结合复合组织靶的能力的核酸配体以及获得这种配体的方法。 组织靶包括细胞，亚细胞组分，聚集体或细胞，细胞集合和更有序结构。 具体地，描述了外周血单核细胞（PBMC），纤维蛋白凝块和颈动脉的核酸配体。
-
公开(公告)号：US07519806B2
公开(公告)日：2009-04-14
申请号：US11356906
申请日：2006-02-16
申请人： Robert Stutton , Abraham Dowd , Charles Warner , Aaron Koolen , Andrew Stephens , Charles Truell , Sean Connolly
发明人： Robert Stutton , Abraham Dowd , Charles Warner , Aaron Koolen , Andrew Stephens , Charles Truell , Sean Connolly
IPC分类号： G06F9/00
CPC分类号： G06F9/4406
摘要： Some computer operating systems do not permit application programs to perform certain tasks. If there is a desire to perform a forbidden task, a virtual partition (228) is created (610) in a storage device (108), such as a hard disk drive, associated with the computer system (100). The virtual partition (228) is stored as a file within the file system of the storage device (108). Operating system files (414) are installed in the virtual partition (228), and the storage device (108) is configured (616) to boot the computer system (100) using the operating system in the virtual partition. When the task is complete, the computer system (100) is configured to boot using the operating system other than the one in the virtual partition.
摘要翻译： 某些计算机操作系统不允许应用程序执行某些任务。 如果希望执行禁止的任务，则在与计算机系统（100）相关联的存储设备（108）（诸如硬盘驱动器）中创建虚拟分区（610）（610）。 虚拟分区（228）作为文件存储在存储设备（108）的文件系统内。 操作系统文件（414）安装在虚拟分区（228）中，并且存储设备（108）被配置（616）以使用虚拟分区中的操作系统引导计算机系统（100）。 当任务完成时，计算机系统（100）被配置为使用除虚拟分区中的操作系统之外的操作系统进行引导。
-
公开(公告)号：US20060143433A1
公开(公告)日：2006-06-29
申请号：US11356906
申请日：2006-02-16
申请人： Robert Stutton , Abraham Dowd , Charles Warner , Aaron Koolen , Andrew Stephens , Charles Truell , Sean Connolly
发明人： Robert Stutton , Abraham Dowd , Charles Warner , Aaron Koolen , Andrew Stephens , Charles Truell , Sean Connolly
IPC分类号： G06F15/177
CPC分类号： G06F9/4406
摘要： Some computer operating systems do not permit application programs to perform certain tasks. If there is a desire to perform a forbidden task, a virtual partition (228) is created (610) in a storage device (108), such as a hard disk drive, associated with the computer system (100). The virtual partition (228) is stored as a file within the file system of the storage device (108). Operating system files (414) are installed in the virtual partition (228), and the storage device (108) is configured (616) to boot the computer system (100) using the operating system in the virtual partition. When the task is complete, the computer system (100) is configured to boot using the operating system other than the one in the virtual partition.
摘要翻译： 某些计算机操作系统不允许应用程序执行某些任务。 如果希望执行禁止的任务，则在与计算机系统（100）相关联的存储设备（108）（诸如硬盘驱动器）中创建虚拟分区（610）（610）。 虚拟分区（228）作为文件存储在存储设备（108）的文件系统内。 操作系统文件（414）安装在虚拟分区（228）中，并且存储设备（108）被配置（616）以使用虚拟分区中的操作系统引导计算机系统（100）。 当任务完成时，计算机系统（100）被配置为使用除虚拟分区中的操作系统之外的操作系统进行引导。
-
公开(公告)号：US06331394B1
公开(公告)日：2001-12-18
申请号：US09364543
申请日：1999-07-29
申请人： Judy Ruckman , Larry Gold , Andrew Stephens , Nebojsa Janjic
发明人： Judy Ruckman , Larry Gold , Andrew Stephens , Nebojsa Janjic
IPC分类号： C12Q168
CPC分类号： C12N15/115 , C12N2310/16 , C12N2310/322 , C12N2310/3533
摘要： Methods are described for the isolation of nucleic acid ligands to integrins using the SELEX process. SELEX is an acronym for Systematic Evolution of Ligands by EXponential enrichment. The nucleic acid ligands of the present invention are useful as therapeutic and diagnostic agents.
摘要翻译： 描述了使用SELEX方法将核酸配体分离为整联蛋白的方法。 SELEX是指数浓缩的配体的系统演化的缩写。 本发明的核酸配体可用作治疗和诊断剂。
-
10.发明授权
公开(公告)号：US6114120A
公开(公告)日：2000-09-05
申请号：US945909
申请日：1997-10-28
申请人： Kirk B Jensen , Hang Chen , Kevin N. Morris , Andrew Stephens , Larry Gold
发明人： Kirk B Jensen , Hang Chen , Kevin N. Morris , Andrew Stephens , Larry Gold
CPC分类号： A61K47/48092 , A61K47/48076 , C12N15/1048 , C12Q1/6811 , G01N2333/96433
摘要： A new class of nucleic acid compounds, referred to as nucleic acid ligands, have been shown to exist that have a specific binding affinity for three dimensional molecular targets, including cell surface macromolecules. The nucleic acid ligands are identified by the method of the invention referred to as the Systematic Evolution of Ligands by EXponential enrichment (SELEX), wherein a candidate mixture of nucleic acids are iteratively enriched and the high affinity nucleic acids are amplified for further partitioning. The high affinity nucleic acid ligands are useful in capturing target cells.
摘要翻译： PCT No.PCT / US96 / 06060 Sec。 371日期1997年10月28日第 102（e）日期1997年10月28日PCT提交1996年5月1日PCT公布。 公开号WO96 / 34875 日期1996年11月7日已经显示存在一类新的核酸化合物，称为核酸配体，其对三维分子靶标（包括细胞表面大分子）具有特异性结合亲和力。 核酸配体通过本发明的方法鉴定，称为通过扩增富集（SELEX）的配体的系统演化，其中核酸的候选混合物被迭代地富集，并且高亲和力核酸被扩增用于进一步分配。 高亲和力核酸配体可用于捕获靶细胞。
-
-
-
-
-
-
-
-
-
搜索结果
18 条记录 (耗时 0.029 秒)
