利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

39 条记录 (耗时 0.069 秒)

    Polynucleotides and polypeptides encoding a novel metalloprotease, Protease-40b
    1.
    发明申请
    Polynucleotides and polypeptides encoding a novel metalloprotease, Protease-40b 审中-公开
    编码新的金属蛋白酶的多核苷酸和多肽，蛋白酶-40b

    公开(公告)号：US20050118632A1

    公开(公告)日：2005-06-02

    申请号：US10980669

    申请日：2004-11-03

    申请人： Jian Chen ,  Stanley Krystek ,  John Feder ,  Thomas Nelson

    发明人： Jian Chen ,  Stanley Krystek ,  John Feder ,  Thomas Nelson

    IPC分类号： C12N9/64 ,  C12Q1/68 ,  C07H21/04

    CPC分类号： C12N9/6489

    摘要： The present invention provides novel polynucleotides encoding Protease-40b polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel Protease-40b polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供编码蛋白酶-40b多肽的新型多核苷酸，其片段及其同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型蛋白酶-40b多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    POLYNUCLEOTIDE ENCODING A NOVEL ACYL COENZYME A, MONOACYLGLYCEROL ACYLTRANSFERASE-3 (MGAT3), AND USES THEREOF
    7.
    发明申请
    POLYNUCLEOTIDE ENCODING A NOVEL ACYL COENZYME A, MONOACYLGLYCEROL ACYLTRANSFERASE-3 (MGAT3), AND USES THEREOF 审中-公开
    多核苷酸编码新型ACYL COENZYME A，单乙酰胆碱酯酶3（MGAT3）及其用途

    公开(公告)号：US20080019958A1

    公开(公告)日：2008-01-24

    申请号：US11779308

    申请日：2007-07-18

    申请人： John Feder ,  Thomas Nelson ,  Jian Chen ,  Rupalie Meegalla ,  Michael Ramaker ,  Dong Cheng

    发明人： John Feder ,  Thomas Nelson ,  Jian Chen ,  Rupalie Meegalla ,  Michael Ramaker ,  Dong Cheng

    IPC分类号： C07K16/18 ,  A61K38/45 ,  C12N1/00 ,  C12P21/02 ,  C12Q1/48 ,  C12N9/10 ,  A61P1/00

    CPC分类号： C12N9/1029

    摘要： The present invention provides novel polynucleotides encoding MGAT3 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MGAT3 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, such as obesity. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码MGAT3多肽的新型多核苷酸，其片段及其同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型MGAT3多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症如肥胖症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Polynucelotides encoding novel variants of the TRP channel family member, LTRPC3
    9.
    发明申请
    Polynucelotides encoding novel variants of the TRP channel family member, LTRPC3 有权
    Polynucelotides编码TRP通道家族成员LTRPC3的新型变体

    公开(公告)号：US20080118952A1

    公开(公告)日：2008-05-22

    申请号：US11985981

    申请日：2007-11-19

    申请人： Ning Lee ,  Jian Chen ,  John Feder ,  Shujian Wu ,  Michael Blanar ,  David Bol ,  Paul Levesque ,  Lucy Sun

    发明人： Ning Lee ,  Jian Chen ,  John Feder ,  Shujian Wu ,  Michael Blanar ,  David Bol ,  Paul Levesque ,  Lucy Sun

    IPC分类号： C12P21/04 ,  C07K16/00

    CPC分类号： C07K14/705 ,  C07H21/04 ,  C07K16/28 ,  C07K2317/21 ,  C07K2317/56 ,  C07K2317/622

    摘要： The present invention provides novel polynucleotides encoding LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供编码LTRPC3g，LTRPC3h，LTRPC3i，LTRPC3j，LTRPC3k或LTRPC3l多肽的新型多核苷酸，其片段及其同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型LTRPC3g，LTRPC3h，LTRPC3i，LTRPC3j，LTRPC3k或LTRPC3l多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。