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公开(公告)号：US07033827B2
公开(公告)日：2006-04-25
申请号：US10144678
申请日：2002-05-09
申请人： Jiangchun Xu , Davin C. Dillon , Jennifer L. Mitcham , Susan L. Harlocker , Yuqiu Jiang , Robert A. Henderson , Michael D. Kalos , Gary R. Fanger , Marc W. Retter , John A. Stolk , Craig H. Day , Thomas S. Vedvick , Darrick Carter , Samuel X. Li , Aijun Wang , Yasir A. W. Skeiky , William T. Hepler , John Hural , Patricia D. McNeill , Raymond L. Houghton , Carlota Vinals y de Bassols , Teresa M. Foy , Yoshihiro Watanabe , Madeleine Joy Meagher , Ta Deng
发明人： Jiangchun Xu , Davin C. Dillon , Jennifer L. Mitcham , Susan L. Harlocker , Yuqiu Jiang , Robert A. Henderson , Michael D. Kalos , Gary R. Fanger , Marc W. Retter , John A. Stolk , Craig H. Day , Thomas S. Vedvick , Darrick Carter , Samuel X. Li , Aijun Wang , Yasir A. W. Skeiky , William T. Hepler , John Hural , Patricia D. McNeill , Raymond L. Houghton , Carlota Vinals y de Bassols , Teresa M. Foy , Yoshihiro Watanabe , Madeleine Joy Meagher , Ta Deng
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2035/124 , A61K2039/505 , A61K2039/5156 , A61K2039/53 , C07K14/47 , C07K14/4748 , C07K14/705 , C07K16/3069 , C07K2317/34 , C07K2319/00 , C12N9/6424 , C12N2710/14143 , C12N2760/16022
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
摘要翻译： 公开了用于治疗和诊断癌症，特别是前列腺癌的组合物和方法。 说明性组合物包含一种或多种前列腺特异性多肽，其免疫原性部分，编码此类多肽的多核苷酸，表达此类多肽的抗原呈递细胞，以及对表达此类多肽的细胞特异的T细胞。 所公开的组合物可用于例如疾病，特别是前列腺癌的诊断，预防和/或治疗。
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公开(公告)号：US06943236B2
公开(公告)日：2005-09-13
申请号：US10012896
申请日：2001-12-10
申请人： Jiangchun Xu , Davin C. Dillon , Jennifer L. Mitcham , Susan L. Harlocker , Yuqiu Jiang , Michael D. Kalos , Gary R. Fanger , Marc W. Retter , John A. Stolk , Craig H. Day , Thomas S. Vedvick , Darrick Carter , Samuel X. Li , Aijun Wang , Yasir A. W. Skeiky , William T. Hepler , Robert A. Henderson , John Hural , Patricia D. McNeill , Raymond L. Houghton , Carlota Vinals y de Bassols , Teresa M. Foy , Yoshihiro Watanabe , Madeleine Joy Meagher
发明人： Jiangchun Xu , Davin C. Dillon , Jennifer L. Mitcham , Susan L. Harlocker , Yuqiu Jiang , Michael D. Kalos , Gary R. Fanger , Marc W. Retter , John A. Stolk , Craig H. Day , Thomas S. Vedvick , Darrick Carter , Samuel X. Li , Aijun Wang , Yasir A. W. Skeiky , William T. Hepler , Robert A. Henderson , John Hural , Patricia D. McNeill , Raymond L. Houghton , Carlota Vinals y de Bassols , Teresa M. Foy , Yoshihiro Watanabe , Madeleine Joy Meagher
IPC分类号： A61K35/12 , A61K38/00 , A61K39/00 , A61K48/00 , C07K14/11 , C07K14/47 , C07K14/705 , C07K16/30 , C12N9/64 , C07K14/00 , C07H21/02 , C12Q1/68 , C12N1/20
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2035/124 , A61K2039/505 , A61K2039/5156 , A61K2039/53 , C07K14/47 , C07K14/4748 , C07K14/705 , C07K16/3069 , C07K2317/34 , C07K2317/73 , C07K2319/00 , C12N9/6424 , C12N2760/16022
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
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公开(公告)号：US20060269532A1
公开(公告)日：2006-11-30
申请号：US11344932
申请日：2006-02-01
申请人： Jiangchun Xu , Davin Dillon , Jennifer Mitcham , Susan Harlocker , Yuqiu Jiang , Robert Henderson , Michael Kalos , Gary Fanger , Marc Retter , John Stolk , Craig Day , Thomas Vedvick , Darrick Carter , Samuel Li , Aijun Wang , Yasir Skeiky , William Hepler , John Hural , Patricia McNeill , Raymond Houghton , Carlota Vinals y de Bassols , Teresa Foy , Yoshihiro Watanabe , Madeleine Meagher , Ta Deng
发明人： Jiangchun Xu , Davin Dillon , Jennifer Mitcham , Susan Harlocker , Yuqiu Jiang , Robert Henderson , Michael Kalos , Gary Fanger , Marc Retter , John Stolk , Craig Day , Thomas Vedvick , Darrick Carter , Samuel Li , Aijun Wang , Yasir Skeiky , William Hepler , John Hural , Patricia McNeill , Raymond Houghton , Carlota Vinals y de Bassols , Teresa Foy , Yoshihiro Watanabe , Madeleine Meagher , Ta Deng
CPC分类号： C07K14/4748 , A61K2039/505 , C07K16/3069 , C07K2317/34 , C12Q1/68 , C12Q1/6886 , G01N33/57434
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
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公开(公告)号：US07425607B2
公开(公告)日：2008-09-16
申请号：US11301554
申请日：2005-12-13
申请人： Robert A Henderson , Tongtong Wang , Yoshihiro Watanabe , Michael D Kalos , Paul R Sleath , Jeffrey C Johnson , Marc W Retter , Margarita Durham , Darrick Carter , Gary R Fanger , Thomas S Vedvick , Chaitanya S Bangur , Andria McNabb
发明人： Robert A Henderson , Tongtong Wang , Yoshihiro Watanabe , Michael D Kalos , Paul R Sleath , Jeffrey C Johnson , Marc W Retter , Margarita Durham , Darrick Carter , Gary R Fanger , Thomas S Vedvick , Chaitanya S Bangur , Andria McNabb
CPC分类号： C07K14/4748 , A61K38/00 , A61K2039/5154 , A61K2039/5156 , C07K14/47 , C07K16/3023 , C07K2317/34 , C07K2319/00 , C07K2319/02 , C07K2319/21 , C12Q1/6886 , C12Q2600/158 , G01N33/57423
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
摘要翻译： 公开了用于治疗和诊断癌症，特别是肺癌的组合物和方法。 说明性组合物包含一种或多种肺肿瘤多肽，其免疫原性部分，编码这种多肽的多核苷酸，表达此类多肽的抗原呈递细胞，以及对表达该多肽的细胞特异的T细胞。 所公开的组合物可用于例如疾病，特别是肺癌的诊断，预防和/或治疗。
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公开(公告)号：US20080171690A1
公开(公告)日：2008-07-17
申请号：US11929579
申请日：2007-10-30
申请人： Robert A. Henderson , Tongtong Wang , Yoshihiro Watanabe , Michael D. Kalos , Paul R. Sleath , Jeffrey C. Johnson , Marc W. Retter , Margarita Durham , Darrick Carter , Gary R. Fanger , Thomas S. Vedvick , Chaitanya S. Bangur , Andria McNabb
发明人： Robert A. Henderson , Tongtong Wang , Yoshihiro Watanabe , Michael D. Kalos , Paul R. Sleath , Jeffrey C. Johnson , Marc W. Retter , Margarita Durham , Darrick Carter , Gary R. Fanger , Thomas S. Vedvick , Chaitanya S. Bangur , Andria McNabb
CPC分类号： C07K14/4748 , A61K38/00 , A61K2039/5154 , A61K2039/5156 , C07K14/47 , C07K16/3023 , C07K2317/34 , C07K2319/00 , C07K2319/02 , C07K2319/21 , C12Q1/6886 , C12Q2600/158 , G01N33/57423
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
摘要翻译： 公开了用于治疗和诊断癌症，特别是肺癌的组合物和方法。 说明性组合物包含一种或多种肺肿瘤多肽，其免疫原性部分，编码这种多肽的多核苷酸，表达此类多肽的抗原呈递细胞，以及对表达该多肽的细胞特异的T细胞。 所公开的组合物可用于例如疾病，特别是肺癌的诊断，预防和/或治疗。
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公开(公告)号：US20080292633A1
公开(公告)日：2008-11-27
申请号：US11929565
申请日：2007-10-30
申请人： Robert A. Henderson , Tongtong Wang , Yoshihiro Watanabe , Michael D. Kalos , Paul R. Sleath , Jeffrey C. Johnson , Marc W. Retter , Margarita Durham , Darrick Carter , Gary R. Fanger , Thomas S. Vedvick , Chaitanya S. Bangur , Andria McNabb
发明人： Robert A. Henderson , Tongtong Wang , Yoshihiro Watanabe , Michael D. Kalos , Paul R. Sleath , Jeffrey C. Johnson , Marc W. Retter , Margarita Durham , Darrick Carter , Gary R. Fanger , Thomas S. Vedvick , Chaitanya S. Bangur , Andria McNabb
IPC分类号： A61K39/395 , C07H21/00 , C07K14/00 , C12N15/00 , C12N5/00 , A61K35/12 , C07K16/00 , G01N33/574 , C12N5/02
CPC分类号： C07K14/4748 , A61K38/00 , A61K2039/5154 , A61K2039/5156 , C07K14/47 , C07K16/3023 , C07K2317/34 , C07K2319/00 , C07K2319/02 , C07K2319/21 , C12Q1/6886 , C12Q2600/158 , G01N33/57423
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
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公开(公告)号：US20080171048A1
公开(公告)日：2008-07-17
申请号：US11929572
申请日：2007-10-30
申请人： Robert A. Henderson , Tongtong Wang , Yoshihiro Watanabe , Michael D. Kalos , Paul R. Sleath , Jeffrey C. Johnson , Marc W. Retter , Margarita Durham , Darrick Carter , Gary R. Fanger , Thomas S. Vedvick , Chaitanya S. Bangur , Andria McNabb
发明人： Robert A. Henderson , Tongtong Wang , Yoshihiro Watanabe , Michael D. Kalos , Paul R. Sleath , Jeffrey C. Johnson , Marc W. Retter , Margarita Durham , Darrick Carter , Gary R. Fanger , Thomas S. Vedvick , Chaitanya S. Bangur , Andria McNabb
IPC分类号： A61K39/395 , A61K39/00
CPC分类号： C07K14/4748 , A61K38/00 , A61K2039/5154 , A61K2039/5156 , C07K14/47 , C07K16/3023 , C07K2317/34 , C07K2319/00 , C07K2319/02 , C07K2319/21 , C12Q1/6886 , C12Q2600/158 , G01N33/57423
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
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公开(公告)号：US20090062194A1
公开(公告)日：2009-03-05
申请号：US11929772
申请日：2007-10-30
申请人： Tongtong Wang , Robert A. Henderson , Teresa M. Foy , Patricia D. McNeill , Yoshihiro Watanabe , Michael D. Kalos , Gary R. Fanger , Chaitanya S. Bangur
发明人： Tongtong Wang , Robert A. Henderson , Teresa M. Foy , Patricia D. McNeill , Yoshihiro Watanabe , Michael D. Kalos , Gary R. Fanger , Chaitanya S. Bangur
CPC分类号： G01N33/57411 , A61K39/00 , A61K39/0011 , A61K2039/5154 , A61K2039/5158 , A61K2039/53 , A61K2039/545 , C07K14/47 , C07K14/4748 , C07K16/3023 , C07K2317/21 , C07K2317/34 , C07K2317/73 , C07K2319/00 , C07K2319/21 , C07K2319/40 , C12N15/86 , C12N2710/10343 , C12N2710/10371 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/5088 , G01N33/57423
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
摘要翻译： 公开了用于治疗和诊断癌症，特别是肺癌的组合物和方法。 说明性组合物包含一种或多种肺肿瘤多肽，其免疫原性部分，编码这种多肽的多核苷酸，表达此类多肽的抗原呈递细胞，以及对表达该多肽的细胞特异的T细胞。 所公开的组合物可用于例如疾病，特别是肺癌的诊断，预防和/或治疗。
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公开(公告)号：US06858204B2
公开(公告)日：2005-02-22
申请号：US10017754
申请日：2001-10-29
申请人： Robert A. Henderson , Tongtong Wang , Yoshihiro Watanabe , Jeffrey C. Johnson , Marc W. Retter , Margarita Durham , Darrick Carter , Gary R. Fanger , Thomas S. Vedvick , Chaitanya S. Bangur , Andria McNabb
发明人： Robert A. Henderson , Tongtong Wang , Yoshihiro Watanabe , Jeffrey C. Johnson , Marc W. Retter , Margarita Durham , Darrick Carter , Gary R. Fanger , Thomas S. Vedvick , Chaitanya S. Bangur , Andria McNabb
CPC分类号： C07K14/47 , A61K38/00 , A61K2039/5154 , A61K2039/5156 , C07K2319/00 , C12Q1/6886 , C12Q2600/158
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
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公开(公告)号：US20060088527A1
公开(公告)日：2006-04-27
申请号：US11301554
申请日：2005-12-13
申请人： Robert Henderson , Tongtong Wang , Yoshihiro Watanabe , Michael Kalos , Paul Sleath , Jeffrey Johnson , Marc Retter , Margarita Durham , Darrick Carter , Gary Fanger , Thomas Vedvick , Chaitanya Bangur , Andria McNabb
发明人： Robert Henderson , Tongtong Wang , Yoshihiro Watanabe , Michael Kalos , Paul Sleath , Jeffrey Johnson , Marc Retter , Margarita Durham , Darrick Carter , Gary Fanger , Thomas Vedvick , Chaitanya Bangur , Andria McNabb
IPC分类号： A61K39/395 , C07H21/04 , C12N5/06 , C07K16/30
CPC分类号： C07K14/4748 , A61K38/00 , A61K2039/5154 , A61K2039/5156 , C07K14/47 , C07K16/3023 , C07K2317/34 , C07K2319/00 , C07K2319/02 , C07K2319/21 , C12Q1/6886 , C12Q2600/158 , G01N33/57423
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
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