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    Stereoselective synthesis of certain trifluoromethyl-substituted alcohols
    3.
    发明申请
    Stereoselective synthesis of certain trifluoromethyl-substituted alcohols 有权
    某些三氟甲基取代的醇的立体选择性合成

    公开(公告)号：US20050234250A1

    公开(公告)日：2005-10-20

    申请号：US11081063

    申请日：2005-03-15

    申请人： Thomas Lee ,  John Proudfoot

    发明人： Thomas Lee ,  John Proudfoot

    IPC分类号： C07D301/02 ,  C07D303/08 ,  C07D303/22 ,  C07D407/06 ,  C07D33/02

    CPC分类号： C07D303/22 ,  C07D301/02 ,  C07D303/08 ,  C07D407/06

    摘要： A process for stereoselective synthesis of a compound of Formula (X) or Formula (X′) wherein R1, R2, and R3 are as defined herein, the process comprising: (a) reacting the starting material of formula A with a chiral sulfoxide anion source in a suitable solvent to prepare a compound of formula C or C′; (b) reducing the sulfoxide of formula C or C′ in a suitable solvent to obtain the compound of formula D or D1; and (c) cyclizing the compound of formula D or D′ in a suitable solvent to form the epoxide compound of Formula (X) or Formula (X′), or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.

    摘要翻译： 用于立体选择性合成式（X）或式（X'）的化合物的方法，其中R 1，R 2和R 3， 所述方法包括：（a）使式A的原料与手性亚砜阴离子源在合适的溶剂中反应以制备式C或C'的化合物; （b）在合适的溶剂中还原式C或C'的亚砜，得到式D或D 1的化合物; 和（c）在合适的溶剂中使式D或D'化合物环化以形成式（X）或式（X'）的环氧化合物或其互变异构体，前药，溶剂合物或盐; 含有这些化合物的药物组合物，以及调节糖皮质激素受体功能的方法和治疗由糖皮质激素受体功能介导的疾病状态或病症的方法，或其特征在于使用这些化合物的患者的炎症，过敏或增殖过程。

    Liquid Extraction For Trash Compactor
    7.
    发明申请
    Liquid Extraction For Trash Compactor 有权
    垃圾压实机液体提取

    公开(公告)号：US20110259210A1

    公开(公告)日：2011-10-27

    申请号：US13094277

    申请日：2011-04-26

    申请人： Fred Reed ,  Thomas Lee

    发明人： Fred Reed ,  Thomas Lee

    IPC分类号： B30B9/04

    CPC分类号： B30B9/06 ,  B30B9/26 ,  B30B9/3039

    摘要： Embodiments of the present relate generally to devices and methods for separating and removing liquid waste from mixed waste. One embodiment relates to a trash compactor having a suction line for removing collected liquid. A further embodiment relates to a trash compactor having a sloped platen for allowing liquid to collect for subsequent removal or drainage.

    摘要翻译： 本发明的实施例一般涉及从混合废物中分离和除去液体废物的装置和方法。 一个实施例涉及具有用于去除收集的液体的吸入管线的垃圾压实机。 另一实施例涉及一种具有倾斜台板的垃圾压实机，用于允许液体收集以用于随后的去除或排水。

    BEVERAGE PRODUCTS AND FLAVOR SYSTEMS HAVING A NON-SWEETENING AMOUNT OF MONATIN
    10.
    发明申请
    BEVERAGE PRODUCTS AND FLAVOR SYSTEMS HAVING A NON-SWEETENING AMOUNT OF MONATIN 审中-公开
    饮料产品和具有不间断金属含量的花生系统

    公开(公告)号：US20090162488A1

    公开(公告)日：2009-06-25

    申请号：US12334937

    申请日：2008-12-15

    申请人： Zena Bell ,  Thomas Lee ,  Larissa Goble

    发明人： Zena Bell ,  Thomas Lee ,  Larissa Goble

    IPC分类号： A23L2/56 ,  A23L2/00 ,  A23L2/60 ,  A23L2/68

    CPC分类号： A23L2/68 ,  A23L2/52 ,  A23L2/56 ,  A23L2/58 ,  A23L2/60 ,  A23L27/31 ,  A23L33/15 ,  A23L33/16

    摘要： Beverage products and flavor systems including a non-sweetening amount of monatin are provided. Beverage concentrate compositions including a non-sweetening amount of monatin are also provided. In addition, methods for making beverages are provided comprising the steps of providing said flavor system, providing at least one additional beverage ingredient, and mixing the flavor system in an amount of 0.01% to 5.0% by weight of the full strength beverage with the at least one additional beverage ingredient to form a full strength beverage.

    摘要翻译： 提供了包含非甜度的莫纳甜的饮料产品和风味系统。 还提供了包含不甜度的莫纳甜的饮料浓缩组合物。 此外，提供了制造饮料的方法，包括以下步骤：提供所述风味剂系统，提供至少一种另外的饮料成分，并将所述风味剂系统的混合量为所述全部强度饮料的0.01重量％至5.0重量％ 至少一种额外的饮料成分以形成全强度饮料。