Method and apparatus for peak compensation in an optical filter
    1.
    发明授权
    Method and apparatus for peak compensation in an optical filter 有权
    光学滤波器中峰值补偿的方法和装置

    公开(公告)号:US07286231B2

    公开(公告)日:2007-10-23

    申请号:US10879630

    申请日:2004-06-30

    IPC分类号: G01J3/51 G01N21/65

    摘要: In one embodiment the disclosure relates to a method and a system for determining the corrected wavelength of a photon scattered by a sample. The method includes the steps of determining a wavelength of a photon scattered from a sample exposed to illuminating photons and passed through a tunable filter and correcting the determined wavelength of the photon as a function of the temperature of the tunable filter and as a function of the bandpass set point of the tunable filter. The step of correcting the determined wavelength can further include determining an offset and adding the offset to the determined wavelength of the photon.

    摘要翻译: 在一个实施例中,本公开涉及一种用于确定由样本散射的光子的校正波长的方法和系统。 该方法包括以下步骤:确定从暴露于照射光子的样品散射的光子的波长,并且通过可调谐滤光器并校正所确定的光子波长作为可调滤光器的温度的函数,并且作为 可调谐滤波器的带通设定点。 校正所确定的波长的步骤还可以包括确定偏移并将偏移量加到所确定的光子的波长上。

    METHOD AND APPARATUS FOR SUPER MONTAGE LARGE AREA SPECTROSCOPIC IMAGING
    3.
    发明申请
    METHOD AND APPARATUS FOR SUPER MONTAGE LARGE AREA SPECTROSCOPIC IMAGING 有权
    超大型区域光谱成像方法与装置

    公开(公告)号:US20090021730A1

    公开(公告)日:2009-01-22

    申请号:US12180344

    申请日:2008-07-25

    IPC分类号: G01J3/44

    摘要: The disclosure relates to Method and Apparatus for Super Montage Large area Spectroscopic Imaging. In one embodiment of the disclosure, a method for producing a spectroscopic image of an object includes the steps of (a) irradiating the object with light to thereby produce from the object scattered and/or emitted (interchangeably “scattered”) light for each of a plurality of wavelengths; (b) producing separately for each of the plurality of wavelengths a plurality of substantially contiguous sub-images of the object; (c) compensating for spatial aberrations in ones of the sub-images for a select one of the plurality of wavelengths; (d) compensating for intensity aberrations between ones of the substantially contiguous sub-images for one of the plurality of wavelengths; and (e) combining the sub-images for the select one wavelength to thereby produce said spectroscopic image of the object.

    摘要翻译: 本公开涉及超级蒙太奇大面积光谱成像方法和装置。 在本公开的一个实施例中,用于产生物体的分光图像的方法包括以下步骤:(a)用光照射物体,从而由物体散射和/或发射(互换地“散射”)的光 多个波长; (b)为所述多个波长中的每一个分别产生所述物体的多个基本相邻的子图像; (c)补偿所述多个波长中的选择一个的子图像中的空间像差; (d)补偿所述多个波长中的一个波长的所述基本连续的子图像中的一个的强度像差; 以及(e)组合所选择的一个波长的子图像,从而产生该对象的所述分光图像。

    Method and apparatus for super montage large area spectroscopic imaging
    4.
    发明授权
    Method and apparatus for super montage large area spectroscopic imaging 有权
    超级蒙太奇大面积光谱成像方法与装置

    公开(公告)号:US07479966B2

    公开(公告)日:2009-01-20

    申请号:US11228382

    申请日:2005-09-19

    摘要: The disclosure relates to Method and Apparatus for Super Montage Large area Spectroscopic Imaging. In one embodiment of the disclosure, a method for producing a spectroscopic image of an object includes the steps of (a) irradiating the object with light to thereby produce from the object scattered and/or emitted light for each of a plurality of wavelengths; (b) producing separately for each of the plurality of wavelengths a plurality of substantially contiguous sub-images of the object; (c) compensating for spatial aberrations in ones of the sub-images for a select one of the plurality of wavelengths; (d) compensating for intensity aberrations between ones of the substantially contiguous sub-images for one of the plurality of wavelengths; and (e) combining the sub-images for the select one wavelength to thereby produce said spectroscopic image of the object.

    摘要翻译: 本公开涉及超级蒙太奇大面积光谱成像方法和装置。 在本公开的一个实施例中,一种用于产生物体的分光图像的方法包括以下步骤:(a)用光照射物体,从而从多个波长中的每一个的物体散射和/或发射光产生; (b)为所述多个波长中的每一个分别产生所述物体的多个基本相邻的子图像; (c)补偿所述多个波长中的选择一个的子图像中的空间像差; (d)补偿所述多个波长中的一个波长的所述基本连续的子图像中的一个的强度像差; 以及(e)组合所选择的一个波长的子图像,从而产生该对象的所述分光图像。

    Method and apparatus for super montage large area spectroscopic imaging
    7.
    发明授权
    Method and apparatus for super montage large area spectroscopic imaging 有权
    超级蒙太奇大面积光谱成像方法与装置

    公开(公告)号:US07705981B2

    公开(公告)日:2010-04-27

    申请号:US12180344

    申请日:2008-07-25

    IPC分类号: G01J3/44

    摘要: The disclosure relates to Method and Apparatus for Super Montage Large area Spectroscopic Imaging. In one embodiment of the disclosure, a method for producing a spectroscopic image of an object includes the steps of (a) irradiating the object with light to thereby produce from the object scattered and/or emitted (interchangeably “scattered”) light for each of a plurality of wavelengths; (b) producing separately for each of the plurality of wavelengths a plurality of substantially contiguous sub-images of the object; (c) compensating for spatial aberrations in ones of the sub-images for a select one of the plurality of wavelengths; (d) compensating for intensity aberrations between ones of the substantially contiguous sub-images for one of the plurality of wavelengths; and (e) combining the sub-images for the select one wavelength to thereby produce said spectroscopic image of the object.

    摘要翻译: 本公开涉及超级蒙太奇大面积光谱成像方法和装置。 在本公开的一个实施例中,用于产生物体的分光图像的方法包括以下步骤:(a)用光照射物体,从而从物体散射和/或发射(互换地“散射”)的光中产生 多个波长; (b)为所述多个波长中的每一个分别产生所述物体的多个基本相邻的子图像; (c)补偿所述多个波长中的选择一个的子图像中的空间像差; (d)补偿所述多个波长中的一个波长的所述基本连续的子图像中的一个的强度像差; 和(e)组合所选择的一个波长的子图像,从而产生该对象的所述分光图像。

    Raman Characterization of Transplant Tissue
    9.
    发明申请
    Raman Characterization of Transplant Tissue 有权
    移植组织的拉曼表征

    公开(公告)号:US20100034743A1

    公开(公告)日:2010-02-11

    申请号:US12537513

    申请日:2009-08-07

    摘要: A system and method for determining a disease state and clinical outcome of a sample. A sample is illuminated to produce Raman scattered photons, the Raman scattered photons are assessed to generate a Raman spectroscopic data set representative of the sample, wherein said Raman spectroscopic data set comprises at least one of: a Raman spectra of the sample and a spatially accurate wavelength resolved Raman image of the sample; the Raman spectroscopic data set is evaluated using a chemometric technique to classify the disease state of the sample as: acute, chronic, incipient, or none. In one embodiment, the chemontric technique is principle component analysis. In another embodiment, the sample is obtained prior to transplantation and analysis can determine the likelihood of rejection by a host.

    摘要翻译: 用于确定样品的疾病状态和临床结果的系统和方法。 照射样品以产生拉曼散射光子,评估拉曼散射光子以产生代表样品的拉曼光谱数据集,其中所述拉曼光谱数据集包括以下至少一个:样品的拉曼光谱和空间准确的 样品的波长分辨拉曼图像; 使用化学计量技术评估拉曼光谱数据集,以将样品的疾病状态分类为急性,慢性,初期或无。 在一个实施方案中,化学方法是主要成分分析。 在另一个实施方案中,在移植之前获得样品,并且分析可以确定宿主排斥的可能性。