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1.发明申请公开(公告)号：US20170321265A1
公开(公告)日：2017-11-09
申请号：US15499005
申请日：2017-04-27
Applicant: Korea Institute of Science and Technology
Inventor： Sang Kyung KIM , Seungwon JUNG
IPC: C12Q1/68
CPC classification number: C12Q1/6853 , B01J2219/00644 , B01J2219/00722 , C12Q1/6834 , C12Q1/686 , C12Q2537/143 , C12Q2563/157
Abstract: A porous matrix according to the present disclosure, wherein a nucleic acid primer-carbon material composite in which one or more nucleic acid primer of a forward primer and a reverse primer as a polymerase chain reaction (PCR) primer is bound to a carbon material is included in the pores of the matrix, provides improved amplification efficiency as compared to a matrix wherein the nucleic acid primer is present on the outer surface of the matrix or a porous matrix wherein the nucleic acid primer is directly fixed inside pores. The porous matrix of the present disclosure can effectively detect various kinds of target nucleic acids simultaneously and analyze them in real time by varying the kinds of the nucleic acid primers included in the matrix. Therefore, it is useful in amplifying multiple nucleic acids.
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公开(公告)号：US20160103108A1
公开(公告)日：2016-04-14
申请号：US14737648
申请日：2015-06-12
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Hyunjung YI , Sang Kyung KIM , Soomi JU , Ki Young LEE
CPC classification number: G01N33/0004 , C07K7/06 , C07K14/005 , C12N2795/14122 , G01N29/022 , G01N29/036 , G01N2291/0256
Abstract: Provided is a peptide selectively binding to a volatile organic compound, in which the peptide has excellent selectivity for the volatile organic compound and has stability at room temperature so as to effectively collect and detect or eliminate the volatile organic compound.
Abstract translation: 提供了选择性结合挥发性有机化合物的肽，其中肽对挥发性有机化合物具有优异的选择性，并且在室温下具有稳定性，从而有效收集和检测或消除挥发性有机化合物。
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公开(公告)号：US20160265028A1
公开(公告)日：2016-09-15
申请号：US15032541
申请日：2014-10-28
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Sang Kyung KIM , Nakwon CHOI , Dong Jin LEE , Seungwon JUNG
IPC: C12Q1/68
CPC classification number: C12Q1/686 , B01J2219/00317 , B01J2219/00644 , B01J2219/00648 , B01J2219/00722 , B01L3/50851 , B01L2200/16 , B01L2300/069 , B01L2300/0819 , C12Q2537/143 , C12Q2563/159 , C12Q2565/519
Abstract: A porous structure according to the present invention has a polymerase chain reaction (PCT) primer inside pores thereof, and hence, even an inner portion thereof can be used unlike general structures of which only surfaces are used for amplification and detection, thereby maximizing reactivity. In addition, the differentiating of the kinds of primers contained in respective structures leads to detection of several kinds of target nucleic acids at the same and real-time analysis thereof at the same time, and thus is useful for multiplex real-time PCR.
Abstract translation: 根据本发明的多孔结构在其孔内具有聚合酶链式反应（PCT）引物，因此，与其仅使用表面用于扩增和检测的一般结构相比，甚至可以使用其内部部分，从而使反应性最大化。 此外，各结构中所含的引物种类的差异导致同时检测多种目标核酸并进行实时分析，因此可用于多重实时PCR。
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4.发明公开公开(公告)号：US20240351220A1
公开(公告)日：2024-10-24
申请号：US18328094
申请日：2023-06-02
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Jeongryul KIM , Keri KIM , Hong Jun CHO , Sang Kyung KIM
CPC classification number: B25J15/0028 , B25J9/1045
Abstract: A gripper for gripping a target has a first support section, a second support section spaced apart from the first support section in a direction of a rotation center axis, and a plurality of elastic wires supported across the first support section and the second support section. A first grip area surrounded by the plurality of elastic wires is formed between the first support section and the second support section upon a relative rotation of the first support section and the second support section around the rotation center axis, and the first grip area becomes narrower until all the plurality of elastic wires come into contact with the target by the relative rotation of the first support section and the second support section, and the plurality of elastic wires is tightened to grip the target entering the first grip area.
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公开(公告)号：US20230358774A1
公开(公告)日：2023-11-09
申请号：US17846623
申请日：2022-06-22
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Keri KIM , Jeongryul KIM , Sang Kyung KIM , Suhun JUNG , Yonghwan MOON , Buchun SONG , Hong Jun CHO
CPC classification number: G01N35/0099 , G01N1/02 , G01N2001/028
Abstract: A specimen collection robot system for performing a specimen collection process having performing specimen collection of a subject with a swab and inserting the swab into a reagent tube has a robot including a gripper and a robot arm. The gripper is configured to grip objects with different diameters by using a same gripping portion. The robot is configured to perform the specimen collection process, by selectively gripping the swab and the reagent tube, without replacing the gripper.
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Patent Agency Ranking
6.发明申请PEPTIDE SELECTIVELY BINDING TO GRAPHITIC MATERIALS AND VOLATILE ORGANIC COMPOUNDS 有权肽选择性地结合成皮材料和挥发性有机化合物公开(公告)号：US20160031938A1
公开(公告)日：2016-02-04
申请号：US14793032
申请日：2015-07-07
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Hyunjung YI , Ki Young LEE , Chaun JANG , Joonyeon CHANG , Sang Kyung KIM , Soomi JU
IPC: C07K7/06
CPC classification number: C07K7/06
Abstract: Provided is a peptide including X2SX1AAX2X3P (SEQ ID NO. 1), X2X2PX3X2AX3P (SEQ ID NO. 2), SX1AAX2X3P (SEQ ID NO. 3), or X2PX3X2AX3P (SEQ ID NO. 4), which bind to graphitic materials or volatile organic compounds.
Abstract translation: 提供了结合石墨材料或挥发性有机物的X2SX1AAX2X3P（SEQ ID NO.1），X2X2PX3X2AX3P（SEQ ID NO.2），SX1AAX2X3P（SEQ ID NO.3）或X2PX3X2AX3P（SEQ ID NO.4）的肽， 化合物。
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公开(公告)号：US20210197201A1
公开(公告)日：2021-07-01
申请号：US17055167
申请日：2019-05-14
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Sang Kyung KIM , Bong Kyun KIM , Jung Min KIM
Abstract: The present invention relates to a porous particle composite for PCR, wherein the porous particle composite distributes photothermal nano-elements that generate heat by absorbing light in porous particles in which nucleic acid amplification occurs through temperature control so as not to adjust the temperature of the entire sample by using a hot plate or the like but to adjust the temperature inside the particles by irradiating light to the porous particles to allow nucleic acid amplification inside thereof, thereby reducing energy consumption and shortening diagnostic time.
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8.发明申请公开(公告)号：US20200239944A1
公开(公告)日：2020-07-30
申请号：US16628346
申请日：2018-07-03
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Sang Kyung KIM , Junsun KIM
IPC: C12Q1/6837 , C12Q1/686 , C12Q1/6853
Abstract: In the present invention, when amplifying a nucleic acid by incorporating at least one primer among a forward primer and reverse primer and/or a probe in an upper critical solution temperature (UCST) particle, or when amplifying a nucleic acid by incorporating at least one primer among the forward primer and reverse primer and/or a probe in a UCST particle and fixing to a hydrogel fine particle, same the primer or probe comprised in the UCST particle can be discharged within a certain temperature range. Accordingly, the formation of primer dimers can be prevented while also achieving excellent PCR amplification efficiency.
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公开(公告)号：US20180364194A1
公开(公告)日：2018-12-20
申请号：US15684939
申请日：2017-08-24
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Kwan Hyi LEE , Minhong JEUN , Seok LEE , Sang Kyung KIM , Sungwook PARK
IPC: G01N27/414 , H01L29/45
Abstract: Provided is a field-effect transistor that can reduce noise, be produced by a simplified manufacturing method, and also have a plurality of active patterns and gate patterns designed to be combinable according to a detection purpose. The field-effect transistor includes a lower silicon layer and a buried oxide layer disposed on the lower silicon layer; an active pattern disposed on the buried oxide layer and including a channel region, a source region, and a drain region; a gate pattern disposed on the active pattern to at least partially overlap the active pattern; a source electrode disposed in direct contact with the source region on the active pattern, and a drain electrode disposed in direct contact with the drain region on the active pattern; and a gate insulating film disposed between the active pattern and the gate pattern.
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10.发明申请公开(公告)号：US20180073972A1
公开(公告)日：2018-03-15
申请号：US15698646
申请日：2017-09-08
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Jaebin CHOI , Chulki KIM , Sang Kyung KIM , Seok LEE , Chaehyun LIM , Jae Hun KIM , Taikjin LEE , Minah SEO
IPC: G01N15/10 , G01N35/08 , G01N15/02 , G01N27/327
Abstract: An apparatus for sensing biomolecules includes: a storage in which a solution containing a target material is received; a sensor configured to sense the target material; and a flow controller connected between the storage and the sensor to supply the solution to the sensor, wherein the flow controller controls a solution flow to supply the solution containing the target material and the solution containing no target material in an alternating manner. According to the apparatus for sensing biomolecules, the sensing device always achieves a sensing offset, and consequently, long-term continuous measurement is enabled, leading to the maximized usage efficiency of the sensor, and the value of quantitative measurement can be obtained with high precision.
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