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9 条记录 (耗时 0.047 秒)

    Novel Glucitol Derivative, Prodrug Thereof And Salt Thereof, And Therapeutic Agent Containing The Same For Diabetes
    4.
    发明申请
    Novel Glucitol Derivative, Prodrug Thereof And Salt Thereof, And Therapeutic Agent Containing The Same For Diabetes 失效
    新型葡萄糖醇衍生物，其药物及其盐，以及含有糖尿病的治疗剂

    公开(公告)号：US20080319047A1

    公开(公告)日：2008-12-25

    申请号：US11658765

    申请日：2005-07-27

    申请人： Hiroharu Matsuoka ,  Tsutomu Sato ,  Masahiro Nishimoto ,  Yasuharu Kato ,  Masahiro Sakaitani ,  Sang-Hak Lee

    发明人： Hiroharu Matsuoka ,  Tsutomu Sato ,  Masahiro Nishimoto ,  Yasuharu Kato ,  Masahiro Sakaitani ,  Sang-Hak Lee

    IPC分类号： C07D409/10 ,  A61K31/381 ,  A61P3/10

    CPC分类号： C07D409/10

    摘要： The invention provides a glucitol derivative having the function of reducing a blood sugar level and having preferable properties required of medicines, such as long-lasting drug activity; and a medicinal composition for use in the prevention or treatment of diseases attributable to hyperglycemia, such as diabetes, complications of diabetes, and obesity. The derivative is a compound represented by the formula (I): wherein m is an integer selected among 1-3; R1 to R4 each independently is optionally substituted alkyl, etc.; Ar1 is optionally substituted naphthyl; and A is optionally substituted heteroaryl, a prodrug of the compound, or a pharmaceutically acceptable salt of either. Also provided are a medicine, a medicinal composition, and the like each containing the compound.

    摘要翻译： 本发明提供了具有降低血糖水平并且具有药物所需的优选性能如持久药物活性的功能的葡糖醇衍生物; 以及用于预防或治疗高血糖疾病如糖尿病，糖尿病并发症和肥胖症的药物组合物。 该衍生物是由式（I）表示的化合物：其中m是选自1-3的整数; R1至R4各自独立地为任选取代的烷基等; Ar1是任选取代的萘基; 和A是任选取代的杂芳基，该化合物的前药或其药学上可接受的盐。 还提供了含有化合物的药物，药物组合物等。

    Method for producing aromatic compound isomers
    6.
    发明授权
    Method for producing aromatic compound isomers 有权
    芳香族化合物异构体的制备方法

    公开(公告)号：US07091389B1

    公开(公告)日：2006-08-15

    申请号：US09648248

    申请日：2000-08-25

    申请人： Masashi Kato ,  Yasuharu Kato ,  Koichi Okada

    发明人： Masashi Kato ,  Yasuharu Kato ,  Koichi Okada

    IPC分类号： C07C17/389 ,  C07C17/38

    CPC分类号： C07C7/13 ,  B01D15/185 ,  B01D2215/023 ,  C07B63/00 ,  C07C17/389 ,  C07C15/067 ,  C07C25/08

    摘要： In a process of producing an aromatic compound isomer substituted with alkyl group(s) and/or halogen atom(s), through adsorptive separation by the use of a zeolite-containing adsorbent and a desorbent, the desorbent is, after having been processed for removing impurities from it, supplied to the adsorptive separation step. In the process, the absorbent used is prevented from being degraded, and its life is prolonged to efficiently separate an aromatic compound isomer mixture into individual isomers.

    摘要翻译： 在制备用烷基和/或卤素原子取代的芳族化合物异构体的方法中，通过使用含沸石的吸附剂和解吸剂进行吸附分离，解吸剂在被处理为 从其中除去杂质，提供给吸附分离步骤。 在此过程中，所使用的吸收剂被防止降解，其使用寿命延长，以有效地将芳族化合物异构体混合物分离为各异构体。

    Shower apparatus
    8.
    发明授权
    Shower apparatus 失效
    淋浴设备

    公开(公告)号：US5428850A

    公开(公告)日：1995-07-04

    申请号：US281651

    申请日：1994-07-28

    申请人： Kazuo Hiraishi ,  Masaru Zaitsu ,  Masanori Sakuragi ,  Yasuharu Kato

    发明人： Kazuo Hiraishi ,  Masaru Zaitsu ,  Masanori Sakuragi ,  Yasuharu Kato

    IPC分类号： E03C1/05 ,  G05D23/13 ,  A47K3/22 ,  E03C1/00

    CPC分类号： G05D23/1393 ,  E03C1/05

    摘要： A shower apparatus is provided with a plurality of shower discharge ports. More specifically, a shower apparatus is provided, in which hot water remains in a hot water line, that is communicated with the shower discharge ports, after the discharge has been completed. The hot water, which has a lower temperature, is drained through a drain valve for disposal of the water in the hot water line and a drain line. At the beginning of the next shower discharge, cold water is thus prevented from being discharged. The operation of an opening and closing valve for effecting discharge and stoppage of each shower discharge port is controlled according to control programs, so that the shower discharge is automatically controlled. The content of the shower discharge, carried out according to the programs, can be changed by a user through the operation of a control section. Moreover, upon the start of the shower discharge, a sudden jet of water is prevented.

    摘要翻译： 淋浴器具有多个喷淋口。 更具体地说，在放电完成之后，设置有淋浴装置，其中热水保持在与热水排放口连通的热水管线中。 具有较低温度的热水通过排水阀排出，用于处理热水管线和排水管线中的水。 在下一次淋浴排放开始时，防止冷水排出。 根据控制程序控制用于实现每个喷淋口的排放和停止的打开和关闭阀的操作，从而自动控制喷淋排放。 根据节目执行的淋浴放电的内容可以由用户通过控制部的操作来改变。 此外，在淋浴喷出开始时，防止了突然的水流。

    Shower apparatus
    9.
    发明授权
    Shower apparatus 失效
    淋浴设备

    公开(公告)号：US5414879A

    公开(公告)日：1995-05-16

    申请号：US164439

    申请日：1993-12-09

    申请人： Kazuo Hiraishi ,  Masaru Zaitsu ,  Masanori Sakuragi ,  Yasuharu Kato

    发明人： Kazuo Hiraishi ,  Masaru Zaitsu ,  Masanori Sakuragi ,  Yasuharu Kato

    IPC分类号： E03C1/05 ,  G05D23/13 ,  A47K3/22

    CPC分类号： G05D23/1393 ,  E03C1/05

    摘要： The present invention is related to a shower apparatus provided with a plurality of shower discharge ports. More specifically, a shower apparatus is disclosed in which hot water remains in a hot water line connected to several shower discharge ports, after a discharge has been completed. Hot water within the hot water line which has lowered in temperature is drained through a drain valve in order to dispose of the water. At the beginning of the next shower discharge, cold water is prevented from being discharged. The operation of an opening and closing valve for effecting discharge and stoppage of each shower discharge port is controlled according to control programs, whereby the shower discharge is substantially controlled. The content of the shower discharge, carried out according to the programs, can be changed by a user through the operation of a central section. Moreover, upon the start of a shower discharge, a sudden jet of water is prevented.

    摘要翻译： 本发明涉及一种具有多个喷淋口的淋浴装置。 更具体地，公开了在放电完成之后，热水保持在连接到多个喷淋口的热水管线中的淋浴设备。 热水管路中温度降低的热水通过排水阀排出，以便处理水。 在下次淋浴排放开始时，防止冷水排出。 根据控制程序控制用于实现每个喷淋口的排放和停止的开闭阀的操作，从而基本上控制喷淋排放。 根据节目进行的淋浴放电的内容可以由用户通过中央部的操作来改变。 此外，在淋浴喷出开始时，防止了突然的水流。